Meningeal carcinomatosis: CSF cytology, immunocytochemistry and biochemical tumor markers.

Abstract:

:CSF cytology, immunocytochemistry and biochemical tumor markers were compared in 12 patients with a meningeal carcinomatosis regarding diagnostic significance and therapy control; 50 samples were investigated. Cytology was tumor-positive in 39 samples and immunocytochemistry in 45 samples. Intrathecally produced tumor markers were found in 47 samples. On initial examination only immunocytochemical testing correctly classified all cases. Cytology and biochemical tumor markers revealed positive results in 10 respectively 11 of 12 patients, combined use of these two methods would increase the sensitivity to 100%. On follow-up examination tumor markers correlated best with symptoms and were early indicators for clinical relapse. These results could be achieved only if several monoclonal antibodies and biochemical tumor marker tests were combined. It is concluded that immunocytochemistry and biochemical tumor markers are of major help regarding the problems of false-negative cytology and reliable therapy control in meningeal carcinomatosis.

journal_name

Acta Neurol Scand

authors

Oschmann P,Kaps M,Völker J,Dorndorf W

doi

10.1111/j.1600-0404.1994.tb02653.x

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

395-9

issue

5

eissn

0001-6314

issn

1600-0404

journal_volume

89

pub_type

杂志文章
  • The cost utility of pitolisant as narcolepsy treatment.

    abstract:OBJECTIVES:The cost-effectiveness of available pharmacological treatments for narcolepsy is largely unknown. Available pharmacological treatments are associated with tolerability, abuse, and adherence issues. Pitolisant is the first inverse agonist of the histamine H3 receptor to be prescribed for the treatment of narc...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13202

    authors: Bolin K,Niska PÅ,Pirhonen L,Wasling P,Landtblom AM

    更新日期:2020-04-01 00:00:00

  • Descriptive epidemiology of physical activity rates in multiple sclerosis.

    abstract:BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12352

    authors: Motl RW,McAuley E,Sandroff BM,Hubbard EA

    更新日期:2015-06-01 00:00:00

  • Algorithm for lamotrigine dose adjustment before, during, and after pregnancy.

    abstract:BACKGROUND:Treatment with lamotrigine (LTG) during pregnancy is associated with a pronounced risk of seizure deterioration, because pregnancy accelerates LTG elimination. The extent to which pregnancy affects LTG pharmacokinetics is unpredictable and varies considerably among patients. AIM:We propose an algorithm for ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2011.01627.x

    authors: Sabers A

    更新日期:2012-07-01 00:00:00

  • Change of the melanocortin system caused by bilateral subthalamic nucleus stimulation in Parkinson's disease.

    abstract::OBJECTIVES - Determine whether bilateral subthalamic nucleus stimulation (STN-DBS) in Parkinson's disease (PD) is associated with an increase in neuropeptide Y (NPY) and/or resistance to inhibition by leptin in relation to post-surgery weight gain. MATERIALS AND METHODS - This prospective study included 20 patients wh...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2010.01469.x

    authors: Escamilla-Sevilla F,Pérez-Navarro MJ,Muñoz-Pasadas M,Sáez-Zea C,Jouma-Katati M,Piédrola-Maroto G,Ramírez-Navarro A,Mínguez-Castellanos A

    更新日期:2011-10-01 00:00:00

  • Incidence of the urological tumours in patients suffering from multiple sclerosis.

    abstract:OBJECTIVES:The goal of this study was to evaluate the incidence of urological malignancies in MS patients using active screening. MATERIAL AND METHODS:A total of 495 MS patients (141 men, 354 women, age of 42±13.4) were included in the study. The duration of disease was 12.3±11 years, and the EDSS score was 4.3 (±2.5)...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12264

    authors: Krhut J,Hradilek P,Nemec D,Tvrdik J,Zapletalova O,Zvara P

    更新日期:2014-09-01 00:00:00

  • Probabilistic ictal EEG sources and temporal lobe epilepsy surgical outcome.

    abstract:OBJECTIVE:For patients with medication refractory medial temporal lobe epilepsy (MTLE), surgery offers the hope of a cure. However, up to 30% of patients with MTLE continue to experience disabling seizures after surgery. The reasons why some patients do not achieve seizure freedom are poorly understood. A promising the...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12253

    authors: Breedlove J,Nesland T,Vandergrift WA 3rd,Betting LE,Bonilha L

    更新日期:2014-08-01 00:00:00

  • Blepharoclonus and Arnold-Chiari malformation.

    abstract:OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.104002113.x

    authors: Jacome DE

    更新日期:2001-08-01 00:00:00

  • Myelin glycosphingolipid immunoreactivity and CSF levels in multiple sclerosis.

    abstract:OBJECTIVES:Patients with multiple sclerosis were reported to harbour antibodies not only against proteins and glycoproteins but also against glycolipids, including sulfatide and galactosylceramide (GalCer), the two major glycosphingolipids of myelin. However, previous results were inconsistent concerning glycosphingoli...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2011.01554.x

    authors: Haghighi S,Lekman A,Nilsson S,Blomqvist M,Andersen O

    更新日期:2012-01-01 00:00:00

  • EMG before and after cervical anterior discectomy.

    abstract:INTRODUCTION:In patients with cervical root syndromes, the relation between clinical findings and EMG results, the value of the registration of the H-reflex latency of the flexor carpi radial muscle (HFCR) and the rate of recovery of EMG abnormalities following surgery are unclear. METHODS:In 68 patients with cervical...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1995.tb00138.x

    authors: van den Bent MJ,Oosting J,Laman DM,van Duijn H

    更新日期:1995-10-01 00:00:00

  • Enzyme-linked immunosorbent assay for detection of antibodies to extractable muscle antigens in myasthenia gravis.

    abstract::A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb04606.x

    authors: Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

    更新日期:1986-06-01 00:00:00

  • Azathioprine reduces intrathecal IgG synthesis in multiple sclerosis.

    abstract::Intrathecal IgG synthesis and CSF oligoclonal bands were reexamined after 18-24 months in 66 patients with multiple sclerosis; 40 of them received azathioprine (AZA) 2.5 mg/Kg/die; all received a course of dexamethasone (DEXA) during clinical relapses. The IgG Index was significantly reduced in the group treated with ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb07899.x

    authors: Caputo D,Zaffaroni M,Ghezzi A,Cazzullo CL

    更新日期:1987-02-01 00:00:00

  • The enhancing effect of multiple sclerosis brain homogenates on the active E-rosette forming lymphocytes in neurological disorders.

    abstract::Peripheral blood lymphocytes from 23 out of 27 (85%) patients with multiple sclerosis responded to MS brain homogenates by increased formation of active E-rosettes. Lymphocytes from only six out of 78 (8%) patients with other neurological diseases responded to MS brain homogenates. The possible value of the test in th...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1979.tb02910.x

    authors: Offner H,Fog T,Rastogi SC,Konat G,Clausen J

    更新日期:1979-03-01 00:00:00

  • Lack of difference in the intimal medial thickness between the left and right carotid arteries in the young.

    abstract:BACKGROUND:Carotid intimal medial thickening (c-IMT) is an established surrogate marker for atherosclerosis. There have been sporadic reports about an increase of c-IMT on the left carotid artery among populations with a mean age of +/-50 years. OBJECTIVE:The purpose of this study was to evaluate whether there is a di...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2007.00828.x

    authors: Arbel Y,Maharshak N,Gal-Oz A,Shapira I,Berliner S,Bornstein NM

    更新日期:2007-06-01 00:00:00

  • Perampanel, an AMPA receptor antagonist: From clinical research to practice in clinical settings.

    abstract::Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/ane.12879

    authors: Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

    更新日期:2018-04-01 00:00:00

  • Body temperature and major neurological improvement in tPA-treated stroke patients.

    abstract:BACKGROUND:Major neurological improvement (MNI) at 24 hours represents a marker of early recanalization in ischaemic stroke. Although low body temperature is considered neuroprotective in cerebral ischaemia, some studies have suggested that higher body temperature may promote clot lysis in the acute phase of ischaemic ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12184

    authors: Kvistad CE,Thomassen L,Waje-Andreassen U,Logallo N,Naess H

    更新日期:2014-05-01 00:00:00

  • Comparative study of visual evoked potentials in spinocerebellar ataxias and multiple sclerosis.

    abstract::Visual evoked potentials (VEPs) were delayed in 11 out of 18 patients with Friedreich's ataxia, in 1 out of 8 patients with Strumpell's hereditary spastic ataxia, in 2 out of 5 cases with cerebellar atrophy and in 42 out of 50 patients with multiple sclerosis (MS). Responses were normal in 5 cases with Pierre Marie's ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb03197.x

    authors: Ghezzi A,Montanini R

    更新日期:1985-03-01 00:00:00

  • Urinary noradrenaline and serotonin metabolites in drug-free Parkinson patients and the effect of L-dopa treatment.

    abstract::3-methoxy-4-hydroxyphenylglycol (MHPG) and 5-hydroxyindoleacetic acid (5-HIAA) as well as homovanillic acid (HVA) and cyclic AMP were estimated in the morning urine of 41 drug-free parkinsonian patients and 25 hospitalized controls. In 29 patients, the estimations were repeated after 2 weeks treatment with L-dopa plus...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1982.tb04524.x

    authors: Markianos M,Hadjikonstantinou M,Bistolaki E

    更新日期:1982-08-01 00:00:00

  • Severe amphethamine-induced bruxism: treatment with botulinum toxin.

    abstract::While chewing and grinding movements have been observed in amphetamine addicts, recognition and management of this problem have rarely been highlighted. Botulinum toxin (BTX) has previously been demonstrated to be effective for bruxism associated with movement disorders, such as cranial-cervical dystonia. However, the...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.02086.x

    authors: See SJ,Tan EK

    更新日期:2003-02-01 00:00:00

  • Well-being in patients with amyotrophic lateral sclerosis and their next of kin over time.

    abstract:OBJECTIVES:The well-being and physical function among patients with ALS and their next of kin was studied over time. MATERIALS AND METHODS:Thirty-five patients with ALS and their next of kin were studied with respect to physical, general and psychological well-being by the visual analogue scale (VAS) every 4-6 months....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01191.x

    authors: Olsson AG,Markhede I,Strang S,Persson LI

    更新日期:2010-04-01 00:00:00

  • General convulsions and rhabdomyolysis. Case reports.

    abstract::Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03746.x

    authors: Os I,Lyngdal PT

    更新日期:1989-03-01 00:00:00

  • Cognitive function in stroke survivors: A 10-year follow-up study.

    abstract:OBJECTIVES:Post-stroke cognitive impairment (PSCI) has considerable impact on patients and society. However, long-term studies on PSCI are scarce and may be influenced by assessment methods and selection bias. We aimed to (i) assess the prevalence of long-term PSCI; (ii) compare two common cognitive assessment instrume...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12709

    authors: Delavaran H,Jönsson AC,Lövkvist H,Iwarsson S,Elmståhl S,Norrving B,Lindgren A

    更新日期:2017-09-01 00:00:00

  • Nerve conduction velocity and circulating immunocomplexes in type 1 diabetic children.

    abstract::There is evidence from several laboratories of an increased prevalence of circulating immuno-complexes (CIC) in diabetic patients. It has also been suggested that CIC are pathogenetically related to chronic diabetic complications. The aim of this study was to assess peripheral nerve function in children with Type 1 di...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb04672.x

    authors: Fierro B,Modica A,Cardella F,Raimondo D,Triolo G,Meli F

    更新日期:1991-03-01 00:00:00

  • Intrathecal interferon in subacute sclerosing panencephalitis.

    abstract::Three patients at Stage II of subacute sclerosing panencephalitis (SSPE) were treated with semipurified alpha-interferon (IFN) using different combinations of intrathecal and intravenous routes: 1 x 10(6) IU of alpha-IFN were given every other day up to a total of 15 x 10(6) IU. Transient improvement of neurological s...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1988.tb03639.x

    authors: Maimone D,Grimaldi LM,Incorpora G,Biondi R,Sofia V,Mancuso GR,Siciliano L,Ruscica M,Pavone L

    更新日期:1988-09-01 00:00:00

  • Oral choline in cerebellar ataxia.

    abstract::In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia. Neither subjectively nor objectively could any statistical significant difference be demonstrated. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb03012.x

    authors: Sehested P,Lund HI,Kristensen O

    更新日期:1980-08-01 00:00:00

  • The value of CT angiography in patients with acute severe headache.

    abstract::Patients with acute severe headache may have a secondary form of headache. Standard head computer tomography (CT) and cerebrospinal fluid (CSF) examination are often performed in the absence of neurological deficits to exclude subarachnoid hemorrhage (SAH). Increasingly, patients undergo subsequent CT angiography (CTA...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12302

    authors: Alons IM,van den Wijngaard IR,Verheul RJ,Lycklama à Nijeholt G,Wermer MJ,Algra A,Jellema K

    更新日期:2015-03-01 00:00:00

  • Isolated seizures in rats do not cause neuronal injury.

    abstract:BACKGROUND:Previous studies have shown that status epilepticus can lead to neuronal injury. However, the effect of a small number of isolated seizures is uncertain. METHODS:We used structural MRI and neuropathology to study the effects of isolated seizures induced by kainic acid (KA), (RS)-2-amino-3-(3-hydroxy-5-tert-...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2011.01521.x

    authors: Acosta MT,Munashinge J,Zhang L,Guerron DA,Vortmeyer A,Theodore WH

    更新日期:2012-01-01 00:00:00

  • A comprehensive electrophysiological evaluation of phrenic nerve injury related to open-heart surgery.

    abstract::A prospective electrophysiological study of phrenic nerve was performed in 59 subjects undergoing open-heart surgery. The nerve was stimulated percutaneously at the neck and the diaphragmatic response was recorded with surface electrodes placed over the 8th intercostal space. The latency, amplitude, duration and area ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb07000.x

    authors: Chroni E,Patel RL,Taub N,Venn GE,Howard RS,Panayiotopoulos CP

    更新日期:1995-04-01 00:00:00

  • Eslicarbazepine acetate in post-stroke epilepsy: Clinical practice evidence from Euro-Esli.

    abstract:OBJECTIVES:To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients included in the Euro-Esli study who had focal seizures associated with post-stroke epilepsy (PSE). MATERIALS AND METHODS:Euro-Esli was a pooled analysis of 14 European clinical practice studies. Effectiveness as...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13323

    authors: Sales F,Chaves J,McMurray R,Loureiro R,Fernandes H,Villanueva V

    更新日期:2020-12-01 00:00:00

  • The epidemiology of post-stroke epilepsy according to stroke subtypes.

    abstract:OBJECTIVES:Strokes represent the most common etiology of epilepsy in patients over the age of 60 years, with an incidence of 2-4% occurring in different studies. MATERIALS AND METHODS:In this observational study, 1,428 patients were included who had stroke and were admitted to our Stroke Unit between the years 1996 an...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00642.x

    authors: Benbir G,Ince B,Bozluolcay M

    更新日期:2006-07-01 00:00:00

  • Is there progressive cognitive dysfunction in Sjögren Syndrome? A preliminary study.

    abstract:OBJECTIVE:The aim of this study was to determine the progression of cognitive dysfunction in primary Sjögren Syndrome (SS). METHODS:Twelve subjects with SS were compared with ten subjects with migraine and ten healthy controls on neuropsychological, mood and fatigue tests at baseline and 8 years later. RESULTS:At fol...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01293.x

    authors: Martínez S,Cáceres C,Mataró M,Escudero D,Latorre P,Dávalos A

    更新日期:2010-09-01 00:00:00