Abstract:
:Only 15% of patients with severe epilepsy with frequent partial seizures achieve any improvement in their seizure frequency by further drug treatment. As we know that epileptic seizures result in neuron loss with early development of mental deterioration, that the mortality rate of patients with epilepsy is increased and that an exact localization of the epileptogenic area which can be resected offers the possibility of curative treatment, we have a moral obligation to make this treatment available to people disabled with epilepsy. Surgery for mesial temporal sclerosis and lesional cortical partial epilepsy offers freedom from seizures in 70-80% of the patients, whereas non-lesional, cortical, partial epilepsy is more problematic, as only 30-40% of the patients will be seizure-free. Volumetric MRI, MR spectroscopy, SPECT and PET reduce the need for invasive monitoring in patients with temporal lobe epilepsy. Invasive recordings should be used when scalp-EEG, MRI, SPECT and PET cannot identify the epileptic focus; 50% of the patients who cannot be diagnosed by non-invasive recordings, can be diagnosed by invasive methods. When operated on 70% become seizure free, and a further 10% achieve a significant improvement. As age at surgery influences vocational outcome, surgical therapy should be considered in children. This will prevent their development into chronically ill patients, with all the known accompanying psychic handicaps this involves.
journal_name
Acta Neurol Scandjournal_title
Acta neurologica Scandinavicaauthors
Dam Mdoi
10.1111/j.1600-0404.1996.tb07034.xsubject
Has Abstractpub_date
1996-08-01 00:00:00pages
81-7issue
2eissn
0001-6314issn
1600-0404journal_volume
94pub_type
杂志文章,评审abstract::Over last fifty years, intravenous (iv) phenytoin (PHT) loading dose has been the treatment of choice for patients with benzodiazepine-resistant convulsive status epilepticus and several guidelines recommended this treatment regimen with simultaneous iv diazepam. Clinical studies have never shown a better efficacy of ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/ane.12928
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:Post-stroke cognitive impairment (PSCI) has considerable impact on patients and society. However, long-term studies on PSCI are scarce and may be influenced by assessment methods and selection bias. We aimed to (i) assess the prevalence of long-term PSCI; (ii) compare two common cognitive assessment instrume...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.12709
更新日期:2017-09-01 00:00:00
abstract::Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1989.tb03746.x
更新日期:1989-03-01 00:00:00
abstract::The level of urinary taurine and 17-hydroxycorticosteroids were estimated in 19 cases of epilepsy. These levels were then compared with those of normal healthy subjects. The urinary taurine levels were significantly higher in epilepsy and have diagnostic as well as prognostic significance. ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1983.tb04853.x
更新日期:1983-12-01 00:00:00
abstract:INTRODUCTION:Cerebrospinal fluid (CSF) may provide markers of severity and outcome of optic neuritis. MATERIAL AND METHODS:We examined the CSF from 29 patients with acute monosymptomatic optic neuritis (AMON) for content of myelin basic protein-like material (MBPLM) and correlated the levels with results of cranial ma...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1996.tb07070.x
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:To investigate the frequency of ECG abnormalities suggestive of myocardial ischaemia in patients with severe drug resistant epilepsy and without any indication of previous cardiac disease, assuming that these changes may be of significance for the group of epileptic patients with sudden unexpected death. MA...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1997.tb00242.x
更新日期:1997-08-01 00:00:00
abstract::This study aimed to systematically review the literature on the epidemiology of epilepsy in Iran and to provide analytical estimates of the prevalence of various epilepsy syndromes. MEDLINE, Scopus, and Embase from inception to 30 July 2020 were systematically searched. These key words were used: "epilepsy" OR "seizur...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/ane.13381
更新日期:2020-11-22 00:00:00
abstract::The etiological characteristics of cerebrovascular disease (CVD) before the age of 55 are reviewed in 399 patients admitted to the Department of Neurology, Karolinska Hospital, Stockholm, from 1973-77. The material was well-defined with regard to subtypes of stroke as well as to the diseased population. The control ma...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1984.tb00846.x
更新日期:1984-12-01 00:00:00
abstract:OBJECTIVE:Guillain-Barre syndrome (GBS) is an acute disease of the peripheral nerves and their roots. Quality of life (QoL) in the first year after acute episode of GBS is still underresearched area. The aim of our study was to investigate QoL in GBS patients during a 6-month follow-up period. METHODS:Multicentric, pr...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/ane.13195
更新日期:2020-03-01 00:00:00
abstract::The spontaneous occurrence of blepharospasm and dystonic movements in face muscles, particularly those of the perioral and mandibular regions, has been named as Meige's disease which was first described by Henry Meige in 1910. We report the case of a woman with Meige's syndrome whose symptoms improved with the use of ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2006.00624.x
更新日期:2006-07-01 00:00:00
abstract::A young woman with firm evidence of early multiple sclerosis (MS), who had never had measles, developed a clinically and serologically evident measles infection. Follow-up 1 year later confirmed the MS diagnosis. Thus, if measles can have a causal role in MS, it is probably not the only agent with this ability. ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1979.tb02932.x
更新日期:1979-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.12417
更新日期:2016-01-01 00:00:00
abstract::Parkinson's disease (PD) surveys and death-record studies in European populations were reviewed. Particular attention was given to methodological aspects. Two sets of quality criteria were used. Four door-to-door surveys revealed underdiagnosis of prevalent idiopathic parkinsonism ranging from 30% to 71%. Quality surv...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,meta分析
doi:10.1111/j.1600-0404.1991.tb04969.x
更新日期:1991-10-01 00:00:00
abstract::IgG subgroups (IgG1, IgG2, IgG3, IgG4) were determined by radioimmunoassay (RIA) in cerebrospinal fluid (CSF) of controls, multiple sclerosis (MS), infectious diseases (ID) and other neurological diseases (OND). The proportion of IgG1 in the total IgG subgroup concentration was significantly higher in the MS group com...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1979.tb02982.x
更新日期:1979-01-01 00:00:00
abstract::Treatment with intraventricular pentosan polysulphate (PPS) might be beneficial in patients with Creutzfeldt-Jakob disease. We report a 68-year-old woman with sporadic Creutzfeldt-Jakob disease who received continuous intraventricular PPS infusion (1-120 microg/kg/day) for 17 months starting 10 months after the onset ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2009.01272.x
更新日期:2010-02-01 00:00:00
abstract::The occurrence of cerebral infarction in patients with transient global amnesia (n = 43) was evaluated by CT scan and compared to that of patients with transient ischemic attacks (TIA) (n = 58) and with no neurological disease (n = 52). Significant differences were demonstrated between TGA and TIA patients in relation...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1986.tb03280.x
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVES:To present clinical features at diagnosis for a large nationwide incident cohort of multiple sclerosis (MS) among those serving in the US military during the Gulf War era (GWE). MATERIALS & METHODS:Medical records and databases from the Department of Veterans Affairs (VA) for cases of MS with onset in or af...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.12810
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:Sparse information on dose-response characteristics for initial antiepileptic drug monotherapy in children with idiopathic generalized epilepsy (IGE) is available. The aim of this study is to characterize the therapeutic dose of valproate in children with newly diagnosed IGE. MATERIALS AND METHODS:Effect of...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2009.01308.x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:Comorbidities of idiopathic normal pressure hydrocephalus (iNPH), such as Alzheimer's disease (AD) and Parkinson's spectrum (PS) disorder, can affect the long-term prognosis of cerebrospinal fluid (CSF) shunting. Therefore, it is important to be able to predict comorbidities in the early stage of the disease...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.13306
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the activity of cortico-cortical (intracortical) inhibitory circuits within the motor cortex in patients with progressive asymmetric limb-kinetic apraxia. MATERIALS AND METHODS:We studied 4 patients with progressive limb-kinetic apraxia whose clinical diagnosis was corticobasal degeneration (CBD...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0404.2000.102004244.x
更新日期:2000-10-01 00:00:00
abstract::Taurine content of 199 clinical muscle biopsies was determined and correlated to histometric data of 121 cases. Taurine concentration in muscles was markedly dependent on fiber type distribution, taurine being more abundant in the slow, oxidative type 1 fibers than in the type 2 fibers. Taurine concentration rose slig...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1990.tb00923.x
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVES:We aimed to study knee proprioception and somatosensory evoked potentials (SEPs) to stimulation of the common peroneal nerve (CPN) in 7 patients with lesion of the anterior cruciate ligament (ACL) before and after ACL reconstruction. MATERIALS AND METHODS:We recorded the spinal N14 and scalp P27 potentials ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1999.tb00680.x
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral infarcts occur more frequently along the middle (MCA) than the anterior cerebral artery (ACA) territory. The reason(s) for this difference remains speculative. The objective of this study was to investigate the distribution of cerebral microemboli as detected by transcranial Doppler ultr...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0404.2000.101002122.x
更新日期:2000-02-01 00:00:00
abstract::There is evidence from several laboratories of an increased prevalence of circulating immuno-complexes (CIC) in diabetic patients. It has also been suggested that CIC are pathogenetically related to chronic diabetic complications. The aim of this study was to assess peripheral nerve function in children with Type 1 di...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1991.tb04672.x
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVES:To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients included in the Euro-Esli study who had focal seizures associated with post-stroke epilepsy (PSE). MATERIALS AND METHODS:Euro-Esli was a pooled analysis of 14 European clinical practice studies. Effectiveness as...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.13323
更新日期:2020-12-01 00:00:00
abstract::The main metabolites of the neurotransmitters noradrenaline, dopamine, and serotonin, methoxy-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5HIAA) respectively, were estimated by HPLC with electrochemical detection in CSF samples from 24 patients in coma after head injury, 1 to 1...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1992.tb05064.x
更新日期:1992-08-01 00:00:00
abstract::The clinical findings and pathological changes of the visual pathway of vitamin B12 deficient monkeys have been described. The cellular morphology and counts of the peripheral blood and bone marrow remained normal during the study (nine deficient, three controls: one still alive in each group). Visual impairment was n...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1980.tb02991.x
更新日期:1980-01-01 00:00:00
abstract::Supernatants of peripheral blood lymphocytes (PBL), containing lymphokines, isolated from MS patients and healthy subjects were tested for demyelinating activity in organotypic culture of the rat cerebellum. PBL were isolated on Ficoll-paque gradient and cultures in RPMI 1640 medium for 72 h with or without phytohemag...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1986.tb07853.x
更新日期:1986-09-01 00:00:00
abstract::POEMS or Crow-Fukase syndrome is a multisystemic, clinically malignant disorder of obscure etiology. Peripheral neuropathy and plasma cell dyscrasia are central features. The authors now report 7 Chinese patients with this syndrome in which PCD or paraproteinemia were absent in 6, and 2 had a lymph node histology rese...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1989.tb03916.x
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0404.2002.0o348.x
更新日期:2002-01-01 00:00:00