Comparison between agarose gel electrophoresis and isoelectric focusing of CSF for demonstration of oligoclonal immunoglobulin bands in neurological disorders.

abstract：:While the association of spinal cord tumor and high-pressure hydrocephalus is well known, only 5 cases of spinal cord tumor associated with normotensive hydrocephalus have been reported. Two further cases are described here, discussing the possible pathophysiological mechanism. It is suggested that these patients go t...

journal_title：Acta neurologica Scandinavica

authors： Yarnitsky D,Honigman S,Hemli JA,Bental E

更新日期：1987-10-01 00:00:00

abstract：:We describe the clinical details of 20 elderly patients with idiopathic small fiber neuropathy. This neuropathy is ubiquitous in practice but has not been well characterized. The clinical syndrome is relatively stereotyped and appears to be a frequent cause of burning feet in the elderly. The main features were burnin...

journal_title：Acta neurologica Scandinavica

authors： Gorson KC,Ropper AH

更新日期：1995-11-01 00:00:00

abstract：:Neurotropin was found to reduce brain oedema in an experimental model of brain infarction in the guinea-pig. A randomized double-blind controlled trial with Neurotropin was performed in 220 patients admitted within 24 h after an acute ischemic stroke. 35 of the neurotropin and 41 of the placebo-randomized patients had...

journal_title：Acta neurologica Scandinavica

authors： De Reuck J,Decoo D,Vanderdonckt P,Dallenga A,Ceusters W,Kalala JP,De Meulemeester K,Abdullah J,Santens P,Huybrechts J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

journal_title：Acta neurologica Scandinavica

authors： Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Sparse information on dose-response characteristics for initial antiepileptic drug monotherapy in children with idiopathic generalized epilepsy (IGE) is available. The aim of this study is to characterize the therapeutic dose of valproate in children with newly diagnosed IGE. MATERIALS AND METHODS:Effect of...

journal_title：Acta neurologica Scandinavica

authors： Holland KD,Monahan S,Morita D,Vartzelis G,Glauser TA

更新日期：2010-03-01 00:00:00

abstract：:IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system ...

journal_title：Acta neurologica Scandinavica

authors： Liedtke W,Weller M,Wiethölter H,Dichgans J

更新日期：1992-03-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) deletions have been noted in small quantities in a handful of atypical cases of myotonic dystrophy and there are clinical and pathological parallels between this autosomal dominant disease and certain mitochondrial myopathies where such deletions are well recognised. We studied 20 individuals...

journal_title：Acta neurologica Scandinavica

authors： Thyagarajan D,Byrne E,Noer S,Lertrit P,Utthanophol P,Kapsa R,Marzuki S

更新日期：1993-01-01 00:00:00

abstract：:In order to characterize the CSF (cerebrospinal fluid) lymphocytes in CNS (central nervous system) inflammation, we examined paired samples of CSF and PB (peripheral blood) of 19 patients with acute aseptic meningitis, performing the dual labelling method on flow cytometry. Significantly higher percentages of CD3+ (T ...

journal_title：Acta neurologica Scandinavica

authors： Uchihara T,Ikeda M,Takahashi H,Yoshida S,Tsukagoshi H

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:The quality-of-life (QoL) perception by Parkinson's disease (PD) patients and their caregivers (CG) has not been studied in depth. OBJECTIVE:To examine patient/proxy agreements on the PD QoL Questionnaire (PDQ-39), the Scale of Quality of Life of Care-Givers (SQLC) and the Multidimensional Caregiver Strain ...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Korczyn AD,Knaani J,Migirov AA,Gurevich T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to evaluate the incidence of urological malignancies in MS patients using active screening. MATERIAL AND METHODS:A total of 495 MS patients (141 men, 354 women, age of 42±13.4) were included in the study. The duration of disease was 12.3±11 years, and the EDSS score was 4.3 (±2.5)...

journal_title：Acta neurologica Scandinavica

authors： Krhut J,Hradilek P,Nemec D,Tvrdik J,Zapletalova O,Zvara P

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Autoimmune encephalitis (AE) is a rare but debilitating neurological disease where the body develops antibodies against neuronal cell surface/synaptic proteins. Rituximab is an anti-CD20 chimeric monoclonal antibody which shows promise in AE treatment observational studies. To our knowledge, there has been n...

journal_title：Acta neurologica Scandinavica

authors： Nepal G,Shing YK,Yadav JK,Rehrig JH,Ojha R,Huang DY,Gajurel BP

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The reported sensitivity of transcranial Doppler ultrasonography (TCD) for confirming brain death (BD) ranges from 91% to 100%. We assessed the frequency and causes of false-negative results in TCD examination in a series of patients with BD and in the literature. METHODS:We carried out a prospective TCD exa...

journal_title：Acta neurologica Scandinavica

authors： de Freitas GR,André C

更新日期：2006-06-01 00:00:00

abstract：:The clinical features in 268 patients with diffuse cerebral atrophy of initially unknown origin have been analysed. Pneumoencephalography showed supratentorial ventricular atrophy in 87 per cent (cortical in 71 per cent), and brain stem and/or cerebellar atrophy in 17 per cent of the patients. Epileptic seizures, dizz...

journal_title：Acta neurologica Scandinavica

authors： Iivanainen M

更新日期：1975-04-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the psychometric properties of the General Self-Efficacy Scale (GSE) in people with Parkinson's disease (PD). More specifically, we investigated data completeness, scaling assumptions, targeting, reliability, and construct validity. MATERIALS AND METHODS:This study involves da...

journal_title：Acta neurologica Scandinavica

authors： Nilsson MH,Hagell P,Iwarsson S

更新日期：2015-08-01 00:00:00

abstract：:The dibenzazepines particularly carbamazepine are associated with known adverse effects (AEs) and drug to drug interactions. Eslicarbazepine acetate (ESL) is structurally distinct from other members of the dibenzazepine family and has the advantage of once daily dosing. Observational and trial data report successful s...

journal_title：Acta neurologica Scandinavica

authors： Watkins L,O'Dwyer M,Oak K,Lawthom C,Maguire M,Thomas R,Shankar R

更新日期：2020-08-01 00:00:00

abstract：:Prognosticating the outcome of an unconscious patient continues to pose a serious challenge to the clinicians. BAERs are the latest addition to neurological diagnostic aids for predicting the outcome of coma. The relative value of BAERs in predicting the outcome of 15 comatosed meningoencephalitis patients has been st...

journal_title：Acta neurologica Scandinavica

authors： Jain S,Maheshwari MC

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pain is common in post-stroke patients and has been shown to be associated with depression, fatigue, and decreased quality of life (QOL). However, studies examining different types of post-stroke pain are scarce. We investigated differences in the related factors and their QOL impacts between mus...

journal_title：Acta neurologica Scandinavica

authors： Choi-Kwon S,Choi SH,Suh M,Choi S,Cho KH,Nah HW,Song H,Kim JS

更新日期：2017-04-01 00:00:00

abstract：:In Sweden, the annual incidence of surgery for hydrocephalus was 3.4 per 100,000 adults between the years 1996 and 1998. The most common indication for surgery was normal pressure hydrocephalus (NPH; 47%), followed by high-pressure hydrocephalus (27%). Seventy-three percent of the patients had communicating hydrocepha...

journal_title：Acta neurologica Scandinavica

authors： Tisell M,Höglund M,Wikkelsø C

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:It was shown previously that low-Mg2+-induced epileptiform activity in rat entorhinal cortex slices changes with time from a pattern of serial seizure-like events (SLEs) to a state of continuously recurring epileptiform activity. Valproic acid blocked the early SLEs but not the late activity. It was proposed...

journal_title：Acta neurologica Scandinavica

authors： Dreier JP,Zhang CL,Heinemann U

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Cystatin C (CysC) is associated with many neurodegenerative disorders and autoimmune diseases, but its relationship with anti-N-Methyl-D-aspartate receptor (anti-NMDAR) encephalitis is unknown. METHODS:Serum levels of CysC were determined in 66 patients with anti-NMDAR encephalitis and 115 healthy controls....

journal_title：Acta neurologica Scandinavica

authors： Shu Y,Chang Y,Wu H,Li J,Cao B,Sun X,Wang J,Peng L,Hu X,Yu X,Qiu W

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

journal_title：Acta neurologica Scandinavica

authors： Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVE:LMNB1-related autosomal dominant leukodystrophy is caused by an overexpression of the protein lamin B1, usually due to a duplication of the LMNB1 gene. Symptoms start in 5th to 6th decade. This slowly progressive disease terminates with death. We studied brain glucose metabolism in this disease using 18 F-flu...

journal_title：Acta neurologica Scandinavica

authors： Finnsson J,Lubberink M,Savitcheva I,Fällmar D,Melberg A,Kumlien E,Raininko R

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that white matter lesions (WMLs) is an important risk factor for cognitive impairment, but the underlying mechanisms have not been clarified. OBJECTIVE:We tested the hypothesis that the cognitive impairments associated with periventricular white matter hyperintensities (PWMHs) on...

journal_title：Acta neurologica Scandinavica

authors： Zi W,Duan D,Zheng J

更新日期：2014-09-01 00:00:00

abstract：:Using the macrophage electrophoretic mobility (MEM) test, the in vitro effects of oleic, linoleic and arachidonic acid, as well as Naudicell oil and methyl gamma-linolenate, on lymphocyte response to various antigens (PPD, thyroid antigen and EF) were studied in patients with mutiple sclerosis, patients with other neu...

journal_title：Acta neurologica Scandinavica

authors： Field EJ,Shenton BK

更新日期：1975-08-01 00:00:00

abstract：:The data for 125 patients with Spielmeyer-Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combination of sodium selenite and vitamin E in 14 of the 27 patients. T...

journal_title：Acta neurologica Scandinavica

authors： Santavuori P,Westermarck T,Rapola J,Pohja P,Moren R,Lappi M,Vuonnala U

更新日期：1985-02-01 00:00:00

abstract：INTRODUCTION:Most studies revealing intellectual deficits in myotonic dystrophy (MyD) involved heterogeneous groups of patients with respect to intelligence and onset of disease. The present study was undertaken to investigate whether patients with early adult and adult MyD show subtle cognitive deficits despite a norm...

journal_title：Acta neurologica Scandinavica

authors： Van Spaendonck KP,Ter Bruggen JP,Weyn Banningh EW,Maassen BA,Van de Biezenbos JB,Gabreëls FJ

更新日期：1995-06-01 00:00:00

abstract：:In this study levels of neuron-specific enolase (NSE), S-100 protein (S-100) and myelin basic protein (MBP) in cerebrospinal fluid (CSF) of children and adults with distinct neurological disorders were examined. A previous study from our department demonstrated age related reference values for these brain-specific pro...

journal_title：Acta neurologica Scandinavica

authors： Lamers KJ,van Engelen BG,Gabreëls FJ,Hommes OR,Borm GF,Wevers RA

更新日期：1995-09-01 00:00:00

abstract：:Bladder dysfunction with increased voiding frequency and incontinence is a common problem in patients with multiple sclerosis (MS). In the present study, the effect of the synthetic vasopressin analogue, desmopressin, was evaluated on the voiding frequency in 26 patients with MS suffering from socially handicapping vo...

journal_title：Acta neurologica Scandinavica

authors： Fredrikson S

更新日期：1996-07-01 00:00:00

abstract：:We present 2 sibs with autosomal recessive spastic paraparesis and severe amyotrophy of the distal limb muscles. Elaborate neurophysiologic studies disclosed slight to moderate slowing of motor conduction, moderate to severe reduction of motor action potentials, denervation potentials, and increased distal motor laten...

journal_title：Acta neurologica Scandinavica

authors： Bruyn RP,Scheltens P,Lycklama à Nijeholt J,de Jong JM

更新日期：1993-06-01 00:00:00