Nasal spray desmopressin treatment of bladder dysfunction in patients with multiple sclerosis.

Abstract:

:Bladder dysfunction with increased voiding frequency and incontinence is a common problem in patients with multiple sclerosis (MS). In the present study, the effect of the synthetic vasopressin analogue, desmopressin, was evaluated on the voiding frequency in 26 patients with MS suffering from socially handicapping voidings and incontinence problems during daytime. A two-week run-in observation period to establish normal voiding patterns was followed by a double-blind, placebo-controlled cross-over study with 20 micrograms intranasal desmopressin during daily activities. There was a significant decrease in the number of voidings during the 6-h period after intranasal intake of desmopressin. Side effects were well tolerated and there was no hyponatremia or hypertension registered. Intranasal desmopressin is an efficient and well-tolerated treatment of voiding problems in patients with MS during daily activities.

journal_name

Acta Neurol Scand

authors

Fredrikson S

doi

10.1111/j.1600-0404.1996.tb00035.x

subject

Has Abstract

pub_date

1996-07-01 00:00:00

pages

31-4

issue

1

eissn

0001-6314

issn

1600-0404

journal_volume

94

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:1989-05-01 00:00:00

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    更新日期:2012-02-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2009-04-01 00:00:00

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    更新日期:1998-09-01 00:00:00

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    doi:10.1111/j.1600-0404.1986.tb03280.x

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  • "To hundred and twenty4our": a study of transcoding in dementia.

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    doi:

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  • Is there progressive cognitive dysfunction in Sjögren Syndrome? A preliminary study.

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    doi:10.1111/j.1600-0404.2009.01293.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb07016.x

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    更新日期:1995-05-01 00:00:00

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    pub_type: 杂志文章,撤回出版物

    doi:10.1111/ane.12940

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    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ane.12848

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    更新日期:2018-01-01 00:00:00

  • Thrombolytic treatment for stroke in the Scandinavian countries.

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    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1979.tb02923.x

    authors: Koch-Henriksen N,Sehested P

    更新日期:1979-03-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04073.x

    authors: Solari A,Amato MP,Bergamaschi R,Logroscino G,Citterio A,Bochicchio D,Filippini G

    更新日期:1993-01-01 00:00:00

  • Neuropsychological tests are useful for predicting comorbidities of idiopathic normal pressure hydrocephalus.

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    pub_type: 杂志文章

    doi:10.1111/ane.13306

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    pub_type: 杂志文章

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    更新日期:2005-08-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    pub_type: 杂志文章,评审

    doi:

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    更新日期:2001-04-01 00:00:00

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    pub_type: 杂志文章,收录出版

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    更新日期:2006-04-01 00:00:00

  • Effect of sympathetic denervation on chronic cold injuries in rabbit brain. A microangiographical and histological study.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1976.tb04801.x

    authors: West KA,Hassler O

    更新日期:1976-09-01 00:00:00

  • Efficacy of a soft hand brace and a wrist splint for carpal tunnel syndrome: a randomized controlled study.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

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    更新日期:2009-01-01 00:00:00

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    doi:10.1111/j.1600-0404.1996.tb00512.x

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    pub_type: 杂志文章

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