The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA.

Abstract:

OBJECTIVE:To replicate the treatment study by Behan et al. (1990) using current research criteria for Chronic Fatigue Syndrome (CFS). METHOD:Fifty patients who fulfilled the Oxford Criteria for CFS were randomly allocated to treatment with either Efamol Marine or placebo for 3 months. They were seen monthly and completed a physical symptoms checklist and the Beck Inventory for Depression and reported if they were the same, better or worse at the end of the study. RESULTS:Symptoms generally improved with time but not significantly and there were no significant differences between the treatment and placebo groups. Pretreatment red-cell membrane (RBC) lipids of patients compared with age-and sex-matched normal controls showed no significant differences. DISCUSSION:The results of this study contrast sharply with the previous study where 85% of patients had a clinically significant improvement of symptoms with Efamol Marine over a 3-month treatment period.

journal_name

Acta Neurol Scand

authors

Warren G,McKendrick M,Peet M

doi

10.1111/j.1600-0404.1999.tb00667.x

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

112-6

issue

2

eissn

0001-6314

issn

1600-0404

journal_volume

99

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:2019-10-01 00:00:00

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    authors: Oschmann P,Kaps M,Völker J,Dorndorf W

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    更新日期:1995-06-01 00:00:00

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  • The effect of L-Deprenyl on on-off phenomena in Parkinson's disease.

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    pub_type: 临床试验,杂志文章

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    authors: Brodersen P,Philbert A,Gulliksen G,Stigård A

    更新日期:1985-06-01 00:00:00

  • Sarcoplasmic body myopathy--a rare hereditary myopathy with characteristic inclusions.

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    pub_type: 杂志文章

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    pub_type: 临床试验,杂志文章

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  • Intrathecal origin of CSF ribonuclease. Differences between infectious processes of the nervous system and multiple sclerosis.

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    doi:

    authors: Allinquant B,Musenger C,Schuller E

    更新日期:1984-07-01 00:00:00

  • Treatment of a patient with myasthenia gravis using antibodies against CD25.

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    doi:10.1111/j.1600-0404.2007.00919.x

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    更新日期:2008-03-01 00:00:00

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    pub_type: 杂志文章

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    authors: Claus D,Hilz MJ,Hummer I,Neundörfer B

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    pub_type: 杂志文章

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    doi:10.1111/j.1600-0404.1990.tb00983.x

    authors: Geminiani G,Cesana BM,Scigliano G,Soliveri P,Girotti F,Giovannini P,Caraceni T

    更新日期:1990-05-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2015-01-01 00:00:00

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    pub_type: 杂志文章,收录出版

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