Amino acid incorporation into brain subcellular fractions in experimental allergic encephalomyelitis.

abstract：OBJECTIVES:To describe two patients with progressive external ophthalmoplegia (PEO) and mitochondrial myopathy associated with mutations in mitochondrial DNA, encoding the tRNAAsn gene (MT-TN), which have not previously been published with clinical descriptions. MATERIALS & METHODS:Two unrelated patients with PEO were...

journal_title：Acta neurologica Scandinavica

authors： Visuttijai K,Hedberg-Oldfors C,Lindgren U,Nordström S,Elíasdóttir Ó,Lindberg C,Oldfors A

更新日期：2020-08-31 00:00:00

abstract：:X-linked adrenoleukodystrophy/adrenomyeloneuropathy presents a wide variation of clinical manifestations and may mimic several diseases. A screening investigation by measuring plasma saturated very long-chain fatty acids was performed in two groups of patients. Among six patients with hereditary spastic paraparesis on...

journal_title：Acta neurologica Scandinavica

authors： Holmberg BH,Hägg E,Duchek M,Hagenfeldt L

更新日期：1992-02-01 00:00:00

abstract：:The concentrations of IgA, IgG and IgM were determined in sera of 16 patients, all of whom had partial epilepsy and had received CBZ as the only drug since the beginning of therapy. Fifty-three healthy subjects served as controls. Serum concentrations of IgA and IgG were significantly higher in patients than in contro...

journal_title：Acta neurologica Scandinavica

authors： Strandjord RE,Johannessen SI,Aarli JA

更新日期：1980-04-01 00:00:00

abstract：:Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3...

journal_title：Acta neurologica Scandinavica

authors： Nyström B,Stjernschantz J,Smedegård G

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the presence of the afterdischarge activity following M- and F-waves in patients with peripheral neuropathies with or without muscle cramps. MATERIAL AND METHODS:Ten patients with peripheral neuropathies complaining of frequent muscle leg cramps (Group 1) and 14 patients with peripheral neuropat...

journal_title：Acta neurologica Scandinavica

authors： Parisi L,Serrao M,Rossi P,Valente G,Fattapposta F,Pierelli F,Amabile G

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:Although the recovery from Guillain-Barré syndrome (GBS) is good in most patients, some develop permanent severe disability or even die. Early predictors would increase the likelihood to identify patients at risk for poor outcome at the acute stage, allowing them intensified therapeutic intervention. MATERI...

journal_title：Acta neurologica Scandinavica

authors： Axelsson M,Sjögren M,Andersen O,Blennow K,Zetterberg H,Lycke J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To report a peculiar observation of a patient who developed a psychomotor inhibition state after a rapid cessation of lamotrigine (LTG). RESULTS:This man was referred to us at the age of 26 years for presurgical evaluation. His treatment [valproate (VPA), 1200 mg/day and LTG, 200 mg/day] was quickly decreas...

journal_title：Acta neurologica Scandinavica

authors： Gelisse P,Kissani N,Crespel A,Jafari H,Baldy-Moulinier M

更新日期：2002-03-01 00:00:00

abstract：:For patients with Parkinson's disease (PD), excessive daytime sleepiness (PD-EDS) is a debilitating non-motor symptom and may be affected by mood symptoms, especially depression and anxiety. Few neuroimaging works have attempted to identify the neural features of PD-EDS, but various findings were reported. The purpose...

journal_title：Acta neurologica Scandinavica

authors： Wen MC,Chan LL,Tan LCS,Tan EK

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Focal brain ischemia induced in rodents by occlusion of the middle cerebral artery (MCA) is a widely used paradigm of human brain infarct. The objective of this study is to compare the effectiveness and reproducibility of MCA filament occlusion model in rats and mice. MATERIALS AND METHODS:A total of 140 ro...

journal_title：Acta neurologica Scandinavica

authors： Ardehali MR,Rondouin G

更新日期：2003-04-01 00:00:00

abstract：:The catabolism of orally and subcutaneously administered 14C histamine was studied in myotonic dystrophy patients. No definite abnormalities were observed as for subcutaneously administered histamine. The catabolism of orally administered histamine followed two distinct patterns: In patients with a relatively low endo...

journal_title：Acta neurologica Scandinavica

authors： Sjaastad O,Sjaastad OV

更新日期：1977-11-01 00:00:00

abstract：OBJECTIVES:A previous epidemiological study of Parkinson's disease (PD) in the county of Tartu, Estonia, found an adjusted prevalence rate of 152/100 000 persons. We aimed to determine PD prevalence almost 20 years later, as well as evaluate any dynamic changes in disease frequency compared to the first study. METHODS...

journal_title：Acta neurologica Scandinavica

authors： Kadastik-Eerme L,Taba N,Asser T,Taba P

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Risk factors for aseptic intracranial venous occlusive disease are varied but only few epidemiologic studies were performed to verify the relative importance of particular factors. PATIENTS AND METHODS:A 2-year hospital-based prospective study was conducted in two hospitals to identify the clinical charac...

journal_title：Acta neurologica Scandinavica

authors： Najim al-Din AS,Mubaidin A,Wriekat AL,Alqam M

更新日期：1994-12-01 00:00:00

abstract：:Among industrial solvents in present use trichloroethylene belongs to those which have been the concern of most neurological and occupational investigations since the beginning of this century. Reports on a broad spectrum of neurotoxicity are however mostly based on case-studies and accidental circumstances. The objec...

journal_title：Acta neurologica Scandinavica

authors： Rasmussen K,Arlien-Søborg P,Sabroe S

更新日期：1993-03-01 00:00:00

abstract：:The authors tested the effects of 2-Br-ergocriptine (bromocriptine, CB-154), a drug which exerts a mixed agonist-antagonist activity on the dopaminergic receptors, in 12 patients with Huntington Chorea in a double-blind crossover trial. This treatment significantly reduced the abnormal involuntary movements and the di...

journal_title：Acta neurologica Scandinavica

authors： Frattola L,Albiazzati MG,Spano PF,Trabucchi M

更新日期：1977-07-01 00:00:00

abstract：:The etiological characteristics of cerebrovascular disease (CVD) before the age of 55 are reviewed in 399 patients admitted to the Department of Neurology, Karolinska Hospital, Stockholm, from 1973-77. The material was well-defined with regard to subtypes of stroke as well as to the diseased population. The control ma...

journal_title：Acta neurologica Scandinavica

authors： Mettinger KL,Söderström CE,Neiman J

更新日期：1984-12-01 00:00:00

abstract：:We prospectively investigated 131 consecutive cases (both in- and outpatients) of suspected dementia to evaluate the relative frequency of different types of dementia in Chinese patients. Dementia was confirmed in 110 cases (84.0%). In contrast to the Western series, vascular dementia (39.1%) was slightly more frequen...

journal_title：Acta neurologica Scandinavica

authors： Liu HC,Tsou HK,Lin KN,Yan SH,Guo NW,Wang CL,Chiang BN

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：:Bladder dysfunction with increased voiding frequency and incontinence is a common problem in patients with multiple sclerosis (MS). In the present study, the effect of the synthetic vasopressin analogue, desmopressin, was evaluated on the voiding frequency in 26 patients with MS suffering from socially handicapping vo...

journal_title：Acta neurologica Scandinavica

authors： Fredrikson S

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVES:Vascular endothelial growth factor (VEGF) acts in angiogenesis and neuroprotection, although the beneficial effects on experimental ischemic stroke (IS) have not been replicated in clinical studies. We investigated serum VEGF (s-VEGF) in the acute stage (baseline) and 3 months post-stroke in relation to stro...

journal_title：Acta neurologica Scandinavica

authors： Åberg ND,Wall A,Anger O,Jood K,Andreasson U,Blennow K,Zetterberg H,Isgaard J,Jern C,Svensson J

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To determine headache characteristics in the obstructive sleep apnea syndrome (OSAS) and in insomnia. PATIENTS AND METHODS:Fifty-six OSAS patients and 50 insomnia patients were assessed in the same time period. Patients in both groups underwent an accurate interview to investigate headache occurrence and it...

journal_title：Acta neurologica Scandinavica

authors： Alberti A,Mazzotta G,Gallinella E,Sarchielli P

更新日期：2005-05-01 00:00:00

abstract：:The effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS), an unnatural norepinephrine precursor, on alpha 2-adrenergic receptors in platelet membranes were investigated in a patient with familial amyloidotic polyneuropathy, two patients with multiple system atrophy, and two patients with Parkinson's disease. Ea...

journal_title：Acta neurologica Scandinavica

authors： Azuma T,Suzuki T,Sakoda S,Mizuno R,Tsujino S,Kobayashi T,Kishimoto S,Hiraga T,Matsubara T,Yoshida S

更新日期：1991-07-01 00:00:00

abstract：:Serum lipids and the cholesterol concentration in the high density lipoprotein (HDL) fraction were measured in epileptic patients taking either carbamazepine or phenytoin as single drug treatment. There was a significant increase in HDL-cholesterol levels in patients taking both phenytoin and carbamazepine. Serum tota...

journal_title：Acta neurologica Scandinavica

authors： O'Neill B,Callaghan N,Stapleton M,Molloy W

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

journal_title：Acta neurologica Scandinavica

authors： Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVES:Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. MATERIALS AND METHODS:We...

journal_title：Acta neurologica Scandinavica

authors： Goldberg I,Neufeld MY,Auriel E,Gandelman-Marton R

更新日期：2013-07-01 00:00:00

abstract：:The clinical indications for temporal artery biopsy were explored using clinical decision analysis. The analysis indicated that biopsy is most useful in patients with a high likelihood of steroid side effects. It is nearly always useful when the pre-biopsy likelihood of temporal arteritis is low, but loses its value w...

journal_title：Acta neurologica Scandinavica

authors： Nadeau SE

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Mild malformation of cortical dysplasia (mMCD) with oligodendroglial hyperplasia (MOGHE) is an epilepsy-related pathologic entity highlighted in post-surgical specimens of frontal lobe epilepsy (FLE) patients. AIMS OF THE STUDY:We present two temporal lobe epilepsy (TLE) cases with MOGHE and discuss clinica...

journal_title：Acta neurologica Scandinavica

authors： Garganis K,Kokkinos V,Zountsas B,Dinopoulos A,Coras R,Blümcke I

更新日期：2019-10-01 00:00:00

abstract：:Neuroacanthocytosis is a progressive multisystem disease with a wide range of symptoms. The involuntary movements mainly include chorea and orofaciolingual dyskinesias. The descriptive name of the disease refers to the presence of abnormal erythrocytes in peripheral blood. Two siblings are presented. One young female ...

journal_title：Acta neurologica Scandinavica

authors： Aasly J,Skandsen T,Rø M

更新日期：1999-11-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:In this study the frequency of inherited thrombophilic risk factors in a population of German CVT patients and their influence on clinical outcome were evaluated. MATERIAL AND METHODS:Twenty-five patients (age 37.1 +/- 16.3 years) with CVT were screened for inherited coagulation disorders. All participants ...

journal_title：Acta neurologica Scandinavica

authors： Stolz E,Kemkes-Matthes B,Pötzsch B,Hahn M,Kraus J,Wirbartz A,Kaps M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral infarcts occur more frequently along the middle (MCA) than the anterior cerebral artery (ACA) territory. The reason(s) for this difference remains speculative. The objective of this study was to investigate the distribution of cerebral microemboli as detected by transcranial Doppler ultr...

journal_title：Acta neurologica Scandinavica

authors： Wijman CA,Babikian VL,Winter MR,Pochay VE

更新日期：2000-02-01 00:00:00