Effect of long-term L-threo-3,4-dihydroxyphenylserine administration on alpha 2-adrenergic receptors in platelet membranes in neurologic disorders.

abstract：:We compared orosomucoid levels in cerebrospinal fluid (CSF) in patients with aseptic meningitis, multiple sclerosis, ischemic and hemorrhagic stroke, CNS-affecting leukemia/lymphoma, and CNS-tumor with the levels in a reference group not having neurologic diseases. Because of possible blood brain barrier damage, we co...

journal_title：Acta neurologica Scandinavica

authors： Vrethem M,Ohman S,von Schenck H,Forsberg P,Olsson JE

更新日期：1987-05-01 00:00:00

abstract：:A total of 158 recordings of brain stem auditory evoked potentials (BAEPs) were obtained in 121 patients with multiple sclerosis. A statistically significant increased incidence of abnormality and diffusely abnormal recordings was found with increasing duration and severity of symptoms. Alterations in follow-up record...

journal_title：Acta neurologica Scandinavica

authors： Kjaer M

更新日期：1980-03-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to evaluate a psychological therapy program used in the treatment of multiple sclerosis (MS) and including cognitive/behavioral strategies, relaxation training and physical exercise. MATERIAL AND METHODS:The participants were 29 patients with MS recruited from an outpatient u...

journal_title：Acta neurologica Scandinavica

authors： Tesar N,Baumhackl U,Kopp M,Günther V

更新日期：2003-06-01 00:00:00

abstract：:During the period 1935-1976, 200 cases of brain abscess were treated in the University Clinic of Neurosurgery, Rigshospitalet, Copenhagen. 119 patients survived. Out of 40 deaths during the follow-up period, 37 were unrelated to the previous brain abscess. 12 patients emigrated and were lost to follow-up. History and ...

journal_title：Acta neurologica Scandinavica

authors： Nielsen H,Harmsen A,Gyldensted C

更新日期：1983-06-01 00:00:00

abstract：:In this study levels of neuron-specific enolase (NSE), S-100 protein (S-100) and myelin basic protein (MBP) in cerebrospinal fluid (CSF) of children and adults with distinct neurological disorders were examined. A previous study from our department demonstrated age related reference values for these brain-specific pro...

journal_title：Acta neurologica Scandinavica

authors： Lamers KJ,van Engelen BG,Gabreëls FJ,Hommes OR,Borm GF,Wevers RA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:One of recent interesting hypotheses of transient global amnesia (TGA) pathophysiology is the preexisting vulnerability of the memory network in patients with TGA. AIM OF THE STUDY:To verify the hypothesis that patients with recurrent amnestic attacks may have more disrupted structural connectivity than pat...

journal_title：Acta neurologica Scandinavica

authors： Moon Y,Moon WJ,Han SH

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:The LRRK2-G2019S mutation is the most common cause of Parkinson's disease (PD) in North Africa. G2019S-PD has been described as similar to idiopathic with minor clinical differences. The aim of this study was to determine the G2019S-related phenotype and to investigate gender and gene dosage effects on clini...

journal_title：Acta neurologica Scandinavica

authors： Ben Romdhan S,Farhat N,Nasri A,Lesage S,Hdiji O,Ben Djebara M,Landoulsi Z,Stevanin G,Brice A,Damak M,Gouider R,Mhiri C

更新日期：2018-11-01 00:00:00

abstract：:The composition of the free amino acid pools in various brain tumors and in normal brains obtained at surgery or at autopsy is determined with an automatic amino acid analyzer and the results statistically evaluated. The tumors have lower ratios of GABA in the pools than the normal brain; tumors with higher GABA ratio...

journal_title：Acta neurologica Scandinavica

authors： Shibasaki T,Uki J,Kanoh T,Kawafuchi J

更新日期：1979-01-01 00:00:00

abstract：:Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) an...

journal_title：Acta neurologica Scandinavica

authors： Salmaggi A,Baldetorp B,Milanese C,Nespolo A,Parma R,Sandberg-Wollheim M

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:To determine whether anti-GM1 antibodies are increased in Parkinson's disease (PD). METHODS:Serum immunoglobulin M (IgM) and IgG anti-GM1 antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in 147 patients with PD and in 186 age-matched normal control subjects. Sera were assayed at initial...

journal_title：Acta neurologica Scandinavica

authors： Zappia M,Crescibene L,Bosco D,Arabia G,Nicoletti G,Bagalà A,Bastone L,Napoli ID,Caracciolo M,Bonavita S,Di Costanzo A,Gambardella A,Quattrone A

更新日期：2002-07-01 00:00:00

abstract：:Thermal tests were performed in 117 healthy subjects on the face, wrist and leg; 32 were tested on the legs with different rates of cooling and warming. Additionally 2 groups of diabetics (37 patients) were tested. Thermotesting was most sensitive on the legs using a rate of temperature change of 2.5-2.8 oC/s. Warm an...

journal_title：Acta neurologica Scandinavica

authors： Claus D,Hilz MJ,Hummer I,Neundörfer B

更新日期：1987-10-01 00:00:00

abstract：:IgG subgroups (IgG1, IgG2, IgG3, IgG4) were determined by radioimmunoassay (RIA) in cerebrospinal fluid (CSF) of controls, multiple sclerosis (MS), infectious diseases (ID) and other neurological diseases (OND). The proportion of IgG1 in the total IgG subgroup concentration was significantly higher in the MS group com...

journal_title：Acta neurologica Scandinavica

authors： Eickhoff K,Kaschka W,Skvaril F,Theilkaes L,Heipertz R

更新日期：1979-01-01 00:00:00

abstract：:In an attempt to establish the efficacy of the different diagnostic tests, 41 multiple sclerosis (MS) patients at different stages of the disease were studied by means of visual evoked potential (VEP) recording, T-lymphocyte subset determination cerebrospinal fluid (CSF) analysis and magnetic resonance (MR) imaging. M...

journal_title：Acta neurologica Scandinavica

authors： Sola P,Scarpa M,Faglioni P,Sorgato P,Merelli E

更新日期：1989-11-01 00:00:00

abstract：:Stroke although rare in children, is an important cause of morbidity in the paediatric age group. Over a period of 8 years, 43 children (17 boys and 26 girls) in the age groups of 1-16 years (mean 8.02 yrs) presented with stroke which constituted 10% of all strokes in the young and 0.7% of all paediatric admissions. T...

journal_title：Acta neurologica Scandinavica

authors： Nagaraja D,Verma A,Taly AB,Kumar MV,Jayakumar PN

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Major neurological improvement (MNI) at 24 hours represents a marker of early recanalization in ischaemic stroke. Although low body temperature is considered neuroprotective in cerebral ischaemia, some studies have suggested that higher body temperature may promote clot lysis in the acute phase of ischaemic ...

journal_title：Acta neurologica Scandinavica

authors： Kvistad CE,Thomassen L,Waje-Andreassen U,Logallo N,Naess H

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:This study aimed to illuminate adult's experienced quality of life in newly-debuted epilepsy and to test the American instrument Quality of Life Index (QLI) for the first time on an epilepsy population. A second aim was to find appropriate questions to measure patient perceptions in epilepsy. MATERIAL AND M...

journal_title：Acta neurologica Scandinavica

authors： Räty L,Hamrin E,Söderfeldt B

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:There is a paucity of regional cerebral blood flow studies in Japanese encephalitis (JE). In this communication we report clinical, radiological and single photon emission computed tomography findings in subacute and chronic JE patients. MATERIAL AND METHODS:Eight JE patients whose ages ranged between 10 and...

journal_title：Acta neurologica Scandinavica

authors： Kalita J,Das BK,Misra UK

更新日期：1999-04-01 00:00:00

abstract：:Out of a data pool of 1271 patients with Multiple Sclerosis (MS) a total of 109 cases are selected having a sole spinal symptomatology throughout the course of the disease. This group differs in three particular features from the non-spinal forms of MS: In this group there is a higher percentage of females, the age at...

journal_title：Acta neurologica Scandinavica

authors： Poser S,Herrmann-Gremmels I,Wikström J,Poser W

更新日期：1978-02-01 00:00:00

abstract：OBJECTIVE:To clarify the relationship between mitochondrial DNA (mtDNA) sequence variations and phenotypes in patients with A3243G mutation. MATERIALS AND METHODS:We studied whole mtDNA sequences in two families with A3243G mutation and characteristic clinical features. Two brothers in Family 1 had shown thiamine defi...

journal_title：Acta neurologica Scandinavica

authors： Morovvati S,Nakagawa M,Sato Y,Hamada K,Higuchi I,Osame M

更新日期：2002-08-01 00:00:00

abstract：:Although intravenous (i.v.) heparin is widely used as the first line treatment for cerebral venous and sinus thrombosis (CVST), the most appropriate therapy for this disease is still controversial. We report 2 cases of CVST who were successfully treated by means of loco-regional thrombolysis with urokinase. In the fir...

journal_title：Acta neurologica Scandinavica

authors： Buccino G,Scoditti U,Pini M,Menozzi R,Piazza P,Zuccoli P,Mancia D

更新日期：2001-01-01 00:00:00

abstract：:Cerebral blood flow (CBF) was studied in 4 patients with acute reversible ischemia (RIND). To test the ischemic areas' vasoreactivity, CBF was measured by the Xenon-133 inhalation method, before and after acetazolamide injected intravenously. At the baseline CBF study, 3 patients presented hypoperfused areas while one...

journal_title：Acta neurologica Scandinavica

authors： Di Piero V,Pozzilli C,Pantano P,Grasso MG,Fieschi C

更新日期：1989-07-01 00:00:00

abstract：:Decompressive craniectomy is a neurosurgical technique in which a portion of the skull is removed to reduce intracranial pressure. The rationale for this procedure is based on the Monro-Kellie Doctrine; expanding the physical space confining edematous brain tissue after traumatic brain injury will reduce intracranial ...

journal_title：Acta neurologica Scandinavica

authors： Quinn TM,Taylor JJ,Magarik JA,Vought E,Kindy MS,Ellegala DB

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:To study the changes in the burden of informal caregivers of patients with disorders of consciousness (DOC) over time. MATERIALS AND METHODS:Short Form-12, Family Strain Questionnaire, Beck Depression Inventory and Coping Orientations to Problem Experiences were administered. RESULTS:Data collected on 216 ...

journal_title：Acta neurologica Scandinavica

authors： Covelli V,Sattin D,Giovannetti AM,Scaratti C,Willems M,Leonardi M

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：:Forty-eight patients with a clinical diagnosis of Alzheimer's disease, 30 patients with cerebrovascular dementia, and 48 normal controls were assessed with a battery of neuropsychological tests designed to measure the following cognitive processes: orientation to time and place, memory, visual-perceptual and construct...

journal_title：Acta neurologica Scandinavica

authors： Villardita C

更新日期：1993-04-01 00:00:00

abstract：:Rats with different levels of blood glucose concentration were exposed to 10 min of complete brain ischemia achieved by compression of neck vessels by a pneumatic cuff. All normoglycemic rats survived the ischemic period and made the best clinical recovery. Hyperglycemic rats died within 12 h. Seizure activity was obs...

journal_title：Acta neurologica Scandinavica

authors： Siemkowicz E,Hansen AJ

更新日期：1978-07-01 00:00:00

abstract：OBJECTIVES:To assess predictors of headache in patients who had sustained a head injury 22 years earlier. MATERIALS AND METHODS:A questionnaire about headache was sent to 361 subjects hospitalized for head injury in 1974-1975. RESULTS:A total of 249 patients (69%) responded to the questionnaire. The prevalence of hea...

journal_title：Acta neurologica Scandinavica

authors： Nestvold K,Lundar T,Mowinckel P,Stavem K

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...

journal_title：Acta neurologica Scandinavica

authors： Prasad K,Browman G,Srivastava A,Menon G

更新日期：1997-02-01 00:00:00

abstract：:The objective of this paper is to evaluate the accuracy of conventional diagnostic criteria for Parkinson's disease and give an overview of alternative causes to parkinsonian syndromes. We also propose a new approach to the clinical diagnosis of Parkinson's disease, which may improve the diagnostic accuracy. The avail...

journal_title：Acta neurologica Scandinavica

authors： Larsen JP,Dupont E,Tandberg E

更新日期：1994-04-01 00:00:00