Blood pressure variability and leukoaraiosis amount in cerebral small-vessel disease.

Abstract:

OBJECTIVES:To analyze the correlation between blood pressure (BP) variability and leukoaraiosis (LA) amount in patients with symptomatic cerebral small-vessel disease. MATERIALS AND METHODS:We included 25 hypertensive patients: 13 with Binswanger's disease (BD) and 12 with a first-ever lacunar infarction (LI). Baseline office BP was obtained for 3 consecutive weeks. From a 24-h ambulatory BP monitoring performed 1 week later we obtained average systolic (SBP) and diastolic (DBP) BP for daytime, nighttime and 24-h periods. SBP and DBP variability was defined as the within-subject standard deviation of all readings. A standardized cerebral MR was performed in each patient and an LA score was calculated. RESULTS:No statistically significant correlation was obtained between the LA score and any of the following BP values: 1) Baseline SBP and DBP; 2) 24-h, daytime or nighttime SBP and DBP, and 3) 24-h, daytime or nighttime SBP and DBP variability. CONCLUSION:Increased BP variability is not associated with greater amounts of leukoaraiosis.

journal_name

Acta Neurol Scand

authors

Martí-Fàbregas J,Valencia C,Pujol J,García-Sánchez C,Roca-Cusachs A,López-Contreras J,Solé MJ,Martí-Vilalta JL

doi

10.1034/j.1600-0404.2001.00082.x

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

358-63

issue

6

eissn

0001-6314

issn

1600-0404

pii

082

journal_volume

104

pub_type

杂志文章
  • Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors.

    abstract::To investigate the blood-brain barrier (BBB function), serum and cerebrospinal fluid (CSF) from 118 patients with Alzheimer's disease (AD) and 50 healthy controls was analyzed with regard to albumin concentrations. For the AD group, clinical vascular factors were also recorded. The CSF/serum albumin ratio was used as ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb01563.x

    authors: Blennow K,Wallin A,Fredman P,Karlsson I,Gottfries CG,Svennerholm L

    更新日期:1990-04-01 00:00:00

  • Quantitative EEG in type 1 diabetic children with and without episodes of severe hypoglycemia: a controlled, blind study.

    abstract::We investigated the EEG frequency distribution by quantitative EEG (QEEG) in 28 children with type 1 diabetes and 28 age- and sex-matched control children. Among the diabetic children, 15 had experienced episodes of severe hypoglycemia (SH group) and 13 had not experienced such episodes (non-SH group). The EEG analysi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1996.tb00017.x

    authors: Bjørgaas M,Sand T,Gimse R

    更新日期:1996-06-01 00:00:00

  • Respiratory complications related to bulbar dysfunction in motor neuron disease.

    abstract::Bulbar dysfunction resulting from corticobulbar pathway or brainstem neuron degeneration is one of the most important clinical problems encountered in motor neuron disease (MND) and contributes to various respiratory complications which are major causes of morbidity and mortality. Chronic malnutrition as a consequence...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:

    authors: Hadjikoutis S,Wiles CM

    更新日期:2001-04-01 00:00:00

  • Experimental facial myokymia in cat.

    abstract:INTRODUCTION:The objective of this study was to describe facial myokymia in experimental animals accompanying kainic acid affects on facial motor neurons. MATERIAL & METHODS:Anesthetized cats were injected with kainic acid into the pons adjacent to the facial nucleus. Facial movements appeared shortly after the inject...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00062.x

    authors: Zaaroor M,Starr A

    更新日期:1997-01-01 00:00:00

  • 99mTc-TRODAT-1 SPECT study in early Parkinson's disease and essential tremor.

    abstract:OBJECTIVE:The clinical differentiation between early Parkinson's disease (PD) and essential tremor (ET) could be difficult, therefore, the aim of this study was to investigate 99mTc-TRODAT-1 SPECT as an applicable tool in this field. METHODS:99mTc-TRODAT-1 single photon emission computed tomography (SPECT) was perform...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2005.00517.x

    authors: Wang J,Jiang YP,Liu XD,Chen ZP,Yang LQ,Liu CJ,Xiang JD,Su HL

    更新日期:2005-12-01 00:00:00

  • Small vessel disease and clinical outcomes after IV rt-PA treatment.

    abstract:INTRODUCTION:Cerebral small vessel disease (SVD) contributes to dementia and disability in the elderly, and may negatively affect stroke outcomes. We aimed to evaluate to what extent single features and global burden of SVD detected with magnetic resonance (MR) are associated with worse outcomes in patients with ischae...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12745

    authors: Arba F,Inzitari D,Ali M,Warach SJ,Luby M,Lees KR,STIR\/VISTA Imaging Collaboration.

    更新日期:2017-07-01 00:00:00

  • Anxiety in multiple sclerosis is related to depressive symptoms and cognitive complaints.

    abstract:OBJECTIVES:Multiple sclerosis (MS) patients suffer from high levels of anxiety. However, it is unclear which factors are related to anxiety, since study results are inconsistent, and the associated factors have not been examined comprehensively. In this study, we investigated the demographic, disease-related and psycho...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13191

    authors: Wallis O,Bol Y,Köhler S,van Heugten C

    更新日期:2020-03-01 00:00:00

  • Paraplegia following epidural anesthesia. A case report and a literature review.

    abstract::This article reports the case of a man who developed a pure motor paraplegia following epidural anesthesia with a pattern of slow recovery over subsequent months. Reviewing the available literature on post-epidural paraplegia we noted a number of potential etiologies and analyzed their role in its causation. On the ba...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Skouen JS,Wainapel SF,Willock MM

    更新日期:1985-10-01 00:00:00

  • Effects of psychological group therapy in patients with multiple sclerosis.

    abstract:OBJECTIVES:The aim of this pilot study was to evaluate a psychological therapy program used in the treatment of multiple sclerosis (MS) and including cognitive/behavioral strategies, relaxation training and physical exercise. MATERIAL AND METHODS:The participants were 29 patients with MS recruited from an outpatient u...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00077.x

    authors: Tesar N,Baumhackl U,Kopp M,Günther V

    更新日期:2003-06-01 00:00:00

  • Regional cerebral blood flow in various types of brain tumor. Effect of the space-occupying lesion on blood flow in brain tissue close to and remote from tumor site.

    abstract::Regional cerebral blood flow (rCBF) was measured in 23 patients with brain tumors using the 133Xe intra-carotid injection method and a 254 channel gamma camera. The glioblastomas (4) and astrocytomas (4) all showed hyperemia in the tumor and tumor-near region. This was also seen in several meningiomas (4 of 7 cases) i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1982.tb04513.x

    authors: Kuroda K,Skyhøj Olsen T,Lassen NA

    更新日期:1982-08-01 00:00:00

  • Enteric-coated acetylsalicylic acid plus dipyridamole compared with anticoagulants in the prevention of ischemic events in patients with transient ischemic attacks.

    abstract::From December 1976 through March 1982, 188 patients entered an open non-random study carried out on hospitalized patients with a history of transient ischemic attacks or amaurosis fugax. Ninety-two patients received peroral anticoagulants usually combined with heparin treatment during the first days of treatment, and ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb03232.x

    authors: Eriksson SE

    更新日期:1985-06-01 00:00:00

  • Spinal epidural abscess following treatment with rituximab.

    abstract:OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12506

    authors: Avila JD,Živković S

    更新日期:2016-05-01 00:00:00

  • EEG in the differential diagnosis between Alzheimer's disease and vascular dementia.

    abstract::Demented patients with Alzheimer's disease (AD) (n = 67), multi-infarct dementia (MID) (n = 77) and probable vascular dementia (PVD) (n = 45) were studied with electroencephalography (EEG). All patients underwent a routine EEG examination and quantitative EEG was recorded from 14 patients with AD, 20 with MID, and 12 ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1988.tb06971.x

    authors: Erkinjuntti T,Larsen T,Sulkava R,Ketonen L,Laaksonen R,Palo J

    更新日期:1988-01-01 00:00:00

  • Can we face the challenge of expanding use of intravenous immunoglobulin in neurology?

    abstract::The use of high-dose polyclonal intravenous immunoglobulin (IVIG) in the treatment of autoimmune neurological diseases has expanded over the last decade. Based on controlled clinical trials IVIG can be considered currently as the first-line treatment in Guillain-Barré syndrome, chronic inflammatory demyelinating polyn...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0404.2009.01317.x

    authors: Elovaara I,Hietaharju A

    更新日期:2010-11-01 00:00:00

  • Clinical and molecular events in patients with Machado-Joseph disease under lamotrigine therapy.

    abstract:OBJECTIVE:Machado-Joseph disease (MJD)/spinocerebellar ataxia type 3 is an autosomal dominant spinocerebellar degeneration, for which there is no effective treatment. PATIENTS AND METHODS:This study involved the clinical response of lamotrigine (LTG) on six MJD patients with early truncal ataxia and the effect of LTG ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.2005.00405.x

    authors: Liu CS,Hsu HM,Cheng WL,Hsieh M

    更新日期:2005-06-01 00:00:00

  • Is the modulatory effect of pregnancy in multiple sclerosis associated with changes in blood apoptotic molecules?

    abstract:OBJECTIVE:We examined whether the modulatory effect of pregnancy on multiple sclerosis (MS) is associated with changes in the apoptotic molecules in sera. SUBJECTS AND METHODS:The serum levels of tumor necrosis factor-related apoptosis-inducing ligand (sTRAIL), sFas, Fas ligand (sFasL) and macrophage migration inhibit...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01301.x

    authors: Rinta S,Airas L,Elovaara I

    更新日期:2010-09-01 00:00:00

  • Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy.

    abstract::Fifteen epileptic patients had their dose of anticonvulsant drugs changed twice, each time by 30-50 per cent of the initial medication. Before the dose change, the patients were given six especially adapted mental performance tests, which were designed to measure vigilance, reaction time and certain aspects of memory....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1975.tb05827.x

    authors: Dekaban AS,Lehman EJ

    更新日期:1975-10-01 00:00:00

  • Autosomal recessive paraparesis with amyotrophy of the hands and feet.

    abstract::We present 2 sibs with autosomal recessive spastic paraparesis and severe amyotrophy of the distal limb muscles. Elaborate neurophysiologic studies disclosed slight to moderate slowing of motor conduction, moderate to severe reduction of motor action potentials, denervation potentials, and increased distal motor laten...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04133.x

    authors: Bruyn RP,Scheltens P,Lycklama à Nijeholt J,de Jong JM

    更新日期:1993-06-01 00:00:00

  • CSF lymphocyte subsets in aseptic meningitis: dual-labelling analysis with flow cytometry.

    abstract::In order to characterize the CSF (cerebrospinal fluid) lymphocytes in CNS (central nervous system) inflammation, we examined paired samples of CSF and PB (peripheral blood) of 19 patients with acute aseptic meningitis, performing the dual labelling method on flow cytometry. Significantly higher percentages of CD3+ (T ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb00997.x

    authors: Uchihara T,Ikeda M,Takahashi H,Yoshida S,Tsukagoshi H

    更新日期:1990-05-01 00:00:00

  • Serum-soluble receptor for advanced glycation end product levels in patients with amyotrophic lateral sclerosis.

    abstract:OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. There is evidence that oxidative stress is implicated in the pathophysiology of the neurodegenerative disorders, including ALS. Data from the literature suggests that the receptor for advanced glycation end products (RAGE) partic...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2008.01133.x

    authors: Iłzecka J

    更新日期:2009-08-01 00:00:00

  • Experimental studies and controlled clinical testing of valproate and vigabatrin.

    abstract::Gamma-aminobutyric acid (GABA) is the most important inhibitory transmitter, quantitatively, in the CNS. Evidence exists that decreased GABAergic neurotransmission may play a role in some forms of epilepsy. Consequently, manipulating the GABA system may be a therapeutic possibility in the treatment of this disease. In...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,评审

    doi:10.1111/j.1600-0404.1988.tb03655.x

    authors: Gram L

    更新日期:1988-10-01 00:00:00

  • The increasing prevalence of Parkinson's disease in Estonia.

    abstract:OBJECTIVES:A previous epidemiological study of Parkinson's disease (PD) in the county of Tartu, Estonia, found an adjusted prevalence rate of 152/100 000 persons. We aimed to determine PD prevalence almost 20 years later, as well as evaluate any dynamic changes in disease frequency compared to the first study. METHODS...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12948

    authors: Kadastik-Eerme L,Taba N,Asser T,Taba P

    更新日期:2018-09-01 00:00:00

  • Blepharoclonus and Arnold-Chiari malformation.

    abstract:OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.104002113.x

    authors: Jacome DE

    更新日期:2001-08-01 00:00:00

  • The excretion patterns of urinary glucosaminoglycans in a family with progressive familial myoclonus epilepsy.

    abstract::The urinary excretion of uronic acid and the electrophoretic composition of urinary glucosaminoglycans were studied in 10 members of a family, of which 3 had progressive familial myoclonus epilepsy. This seems to be the first detailed investigation of the excretion of urinary glucosaminoglycans in patients suffering f...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1975.tb05776.x

    authors: Poulsen JH

    更新日期:1975-09-01 00:00:00

  • Normal-pressure hydrocephalus associated with spinal cord tumor.

    abstract::While the association of spinal cord tumor and high-pressure hydrocephalus is well known, only 5 cases of spinal cord tumor associated with normotensive hydrocephalus have been reported. Two further cases are described here, discussing the possible pathophysiological mechanism. It is suggested that these patients go t...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0404.1987.tb03585.x

    authors: Yarnitsky D,Honigman S,Hemli JA,Bental E

    更新日期:1987-10-01 00:00:00

  • Surgery in primary supratentorial intracerebral hematoma: a meta-analysis of randomized trials.

    abstract:OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,meta分析

    doi:10.1111/j.1600-0404.1997.tb00078.x

    authors: Prasad K,Browman G,Srivastava A,Menon G

    更新日期:1997-02-01 00:00:00

  • Risk of multiple sclerosis inversely associated with birth order position.

    abstract::The aim of this study was to ascertain whether there is an association between risk of multiple sclerosis (MS) and birth order position. Our reference population was 198,000 persons born in the period 1930-50 and recorded in the register of school health records from the school health service of the Copenhagen council...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb01509.x

    authors: Isager H,Andersen E,Hyllested K

    更新日期:1980-06-01 00:00:00

  • Epidemiological and clinical characteristics of myasthenia gravis in Belgrade, Yugoslavia (1983-1992).

    abstract::This is the first epidemiological study of myasthenia gravis (MG) in the area of Belgrade. During the survey period (1983 1992), 124 incidental cases of MG were observed, producing an average annual incidence rate of 7.1 per million population (women, 8.3; men, 5.8). Age and sex specific incidence rates for females de...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb00733.x

    authors: Lavrnić D,Jarebinski M,Rakocević-Stojanović V,Stević Z,Lavrnić S,Pavlović S,Trikić R,Tripković I,Nesković V,Apostolski S

    更新日期:1999-09-01 00:00:00

  • Effect of CB 154 (2-bromo-alpha-ergocryptine) on paralysis agitans compared with Madopar in a double-blind, cross-over trial.

    abstract::Twenty patients with paralysis agitans took part in a double-blind, cross-over investigation of CB 154 (2-bromo-alpha-ergocryptine) and Madopar (L-Dopa + benserazid (a peripheral decarboxylase inhibitor), dose ratio 4:1). Each treatment phase lasted for 8 weeks. Modapar was found to be significantly superior to CB 154...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1976.tb04337.x

    authors: Gerlach J

    更新日期:1976-03-01 00:00:00

  • Hip fracture after first-ever stroke: a population-based study.

    abstract:OBJECTIVES:The aim of this study is to estimate the risk of hip fracture after first-ever stroke, using a nationwide population-base data set and a retrospective cohort design. MATERIALS AND METHODS:The cohort study involved 18,413 patients surviving a first-ever stroke during the 12-year period from 1997 to 2008. Ano...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12301

    authors: Lin HL,Lin HC,Tseng YF,Liao HH,Worly JA,Pan CY,Hsu CY

    更新日期:2015-03-01 00:00:00