Serum-soluble receptor for advanced glycation end product levels in patients with amyotrophic lateral sclerosis.

Abstract:

OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. There is evidence that oxidative stress is implicated in the pathophysiology of the neurodegenerative disorders, including ALS. Data from the literature suggests that the receptor for advanced glycation end products (RAGE) participates in pathological conditions, including oxidative stress and neurodegeneration. MATERIALS AND METHODS:The study involved 20 patients with ALS and 20 patients from the control group. The serum-soluble RAGE (sRAGE) levels were measured using the enzyme-linked immunosorbent method. RESULTS:The study showed that sRAGE levels are significantly decreased in serum of the patients with ALS comparing to the control group (P < 0.05). The correlation between the serum sRAGE levels and clinical parameters of the disease was not significant (P > 0.05). CONCLUSIONS:The results indicate that sRAGE participates in pathophysiology of the ALS. It is possible that low sRAGE levels may influence neurodegeneration.

journal_name

Acta Neurol Scand

authors

Iłzecka J

doi

10.1111/j.1600-0404.2008.01133.x

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

119-22

issue

2

eissn

0001-6314

issn

1600-0404

pii

ANE1133

journal_volume

120

pub_type

杂志文章
  • Variations of brain stem auditory evoked potentials correlated to duration and severity of multiple sclerosis.

    abstract::A total of 158 recordings of brain stem auditory evoked potentials (BAEPs) were obtained in 121 patients with multiple sclerosis. A statistically significant increased incidence of abnormality and diffusely abnormal recordings was found with increasing duration and severity of symptoms. Alterations in follow-up record...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb01478.x

    authors: Kjaer M

    更新日期:1980-03-01 00:00:00

  • Temporal lobe epilepsy visualized with PET with 11C-L-deuterium-deprenyl--analysis of kinetic data.

    abstract:OBJECTIVES:The purpose of the study was to develop a simplified method for the acquisition and analysis of data from positron emission tomography (PET) using the ligand 11C-L-deuterium-deprenyl. This is motivated by an increased interest in methods to characterize gliosis in neurodegenerative diseases and epilepsy, whi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1998.tb07300.x

    authors: Bergström M,Kumlien E,Lilja A,Tyrefors N,Westerberg G,Långström B

    更新日期:1998-10-01 00:00:00

  • Magnetic resonance imaging findings in lupus ataxia.

    abstract::We present a 47-year-old white woman who had a definitive diagnosis of systemic lupus erythematosus (SLE), and developed cerebellar ataxia of sudden onset. MR imaging showed changes characteristics of cerebellar infarct. Due to the absence of vascular risk factors and to the previous diagnosis of SLE, we postulate tha...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05111.x

    authors: Lancman ME,Pomeraniec C,Norscini J

    更新日期:1992-10-01 00:00:00

  • Localized outbreak of enteroviral meningitis in adults.

    abstract::During a thorough surveillance of viral infections of the central nervous system an outbreak of aseptic meningitis was discovered in the western part of Finland in late 1985. The 21 diseased young adults were carefully studied by different virological methods. A presumed viral etiology, in all cases of enteroviral ori...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb05457.x

    authors: Kinnunen E,Hovi T,Stenvik M,Hellström O,Porras J,Kleemola M,Kantanen ML

    更新日期:1987-05-01 00:00:00

  • Antioxidant treatment in Spielmeyer-Sjögren's disease.

    abstract::The data for 125 patients with Spielmeyer-Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combination of sodium selenite and vitamin E in 14 of the 27 patients. T...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb03178.x

    authors: Santavuori P,Westermarck T,Rapola J,Pohja P,Moren R,Lappi M,Vuonnala U

    更新日期:1985-02-01 00:00:00

  • Cardiovascular dysautonomia in Parkinson's disease and multiple system atrophy.

    abstract:OBJECTIVES:To determine whether Parkinson's disease (PD) can be distinguished from multiple system atrophy (MSA) on the basis of the assessment of iodine-123 meta-iodobenzylguanidine (123I-MIBG) radioactivity in heart and cardiovascular autonomic function. PATIENTS AND METHODS:Seventeen patients with MSA, 39 with PD, ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,收录出版

    doi:10.1111/j.1600-0404.2005.00526.x

    authors: Oka H,Mochio S,Yoshioka M,Morita M,Onouchi K,Inoue K

    更新日期:2006-04-01 00:00:00

  • Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin.

    abstract:OBJECTIVE:To evaluate the efficacy and tolerability of the treatment with valproic acid (VPA) in patients with status epilepticus (SE) or acute repetitive seizures (ARS) comparing it with phenytoin (PHT) treatment. MATERIALS AND METHODS:Patients with SE or ARS were treated in a consecutive manner with either VPA or PH...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.2008.01097.x

    authors: Gilad R,Izkovitz N,Dabby R,Rapoport A,Sadeh M,Weller B,Lampl Y

    更新日期:2008-11-01 00:00:00

  • A case of anorexia nervosa with acute renal failure resulting from rhabdomyolysis.

    abstract::Symptoms of acute renal failure were observed in an anorexia patient who had a history of frequent vomiting. The acute renal failure might have resulted from rhabdomyolysis subsequent to a disturbance of electrolyte balance. This acute renal failure might have resulted in death if not treated. We postulate that even a...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb00935.x

    authors: Abe K,Mezaki T,Hirono N,Udaka F,Kameyama M

    更新日期:1990-01-01 00:00:00

  • Neurophysiologic evaluation of cyclosporine toxicity associated with bone marrow transplantation.

    abstract:INTRODUCTION:Cortical blindness, a rare form of cyclosporine (CSA) neurotoxicity, has previously been described in only nine bone marrow transplant (BMT) recipients. METHODS:Our institution averages 35 allogeneic BMT's per year. In the past year we have seen two women with reversible cortical blindness secondary to CS...

    journal_title:Acta neurologica Scandinavica

    pub_type: 更正并重新发布的文章,杂志文章,评审

    doi:10.1111/j.1600-0404.1996.tb07081.x

    authors: Edwards LL,Wszolek ZK,Normand MM

    更新日期:1996-11-01 00:00:00

  • Botulinum toxin-A injections vs radiotherapy for drooling in ALS.

    abstract:OBJECTIVES:Botulinum neurotoxin (BoNT) injections in the salivary glands and radiotherapy (RT) on these glands are commonly used to alleviate severe drooling in patients with amyotrophic lateral sclerosis (ALS). This study compares BoNT type A with RT based on patient-rated evaluations. MATERIALS & METHODS:A prospecti...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ane.12559

    authors: Weikamp JG,Schinagl DA,Verstappen CC,Schelhaas HJ,de Swart BJ,Kalf JG

    更新日期:2016-09-01 00:00:00

  • Immune responses in experimental allergic neuritis treated with corticosteroids.

    abstract::The preventive and suppressive effects of methylprednisolone (MP) were investigated in 22 rabbits immunized with peripheral nerve myelin. Cellular reactivity to bovine P2 protein (P2) and anti-P2 antibody were also examined serially in these animals, using the lymphocyte proliferation test or enzyme-linked immunosorbe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1988.tb05942.x

    authors: Ohno R,Hamaguchi K,Nomura K,Sowa K,Tanaka H,Negishi T,Yamashita T

    更新日期:1988-06-01 00:00:00

  • Executive dysfunction in non-demented Parkinson's disease patients with hallucinations.

    abstract:OBJECTIVE:We investigated executive function in Parkinson's disease (PD) patients, and focused on executive dysfunction in PD with hallucinations, but without dementia. METHODS:PD patients were classified by cognitive or neuropsychotic status as PD group, PD with vivid dreaming group, PD with hallucinations group and ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2007.00933.x

    authors: Imamura K,Wada-Isoe K,Kitayama M,Nakashima K

    更新日期:2008-04-01 00:00:00

  • A non-syndromic hearing loss caused by very low levels of the mtDNA A3243G mutation.

    abstract::We described a patient with progressive non-syndromic hearing loss (NSHL) harboring the A3243G mutation in the mitochondrial DNA (mtDNA). Muscle biopsy showed scattered ragged-red, cytochrome c oxidase negative fibers, whereas the biochemical analysis of the mitochondrial respiratory chain complexes was normal. Restri...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00254.x

    authors: Mancuso M,Filosto M,Forli F,Rocchi A,Berrettini S,Siciliano G,Murri L

    更新日期:2004-07-01 00:00:00

  • Neuropsychological screening in the acute phase of cerebrovascular diseases.

    abstract:INTRODUCTION:Cognitive impairment is a common and disabling consequence of stroke. Its prevalence, the best way to screen for it in the acute setting, and its relation with premorbid status have not been thoroughly clarified. MATERIALS AND METHODS:Ischemic and hemorrhagic stroke patients admitted to our stroke unit un...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13319

    authors: Cova I,Mele F,Zerini F,Maggiore L,Cucumo V,Brambilla M,Rosa S,Bertora P,Salvadori E,Pomati S,Pantoni L

    更新日期:2020-10-01 00:00:00

  • Diagnostic radioimmunoassay and DNA-analysis in Swedish and Japanese patients with familial amyloidotic polyneuropathy. Homozygosity for the TTR met30 gene.

    abstract::Eighteen Swedish patients with familial amyloidotic polyneuropathy were tested for the met30 mutation of the transthyretin (TTR) (prealbumin) gene by RFLP analysis of genomic DNA using the restriction enzyme NsiI. The results confirmed previous findings that the Swedish variant of familial polyneuropathy has the same ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04090.x

    authors: Holmgren G,Lundgren E,Kangawa K,Kurihara T,Matsukura S,Matsuo H,Nakazato M,Steen L

    更新日期:1993-02-01 00:00:00

  • Cerebrospinal fluid biomarkers in patients with neurological symptoms but without neurological diseases.

    abstract:BACKGROUND:Elevated levels of the cerebrospinal fluid (CSF) neuronal injury markers (neurofilament light chain [NF-L] and total tau protein [t-tau]) and of the astroglial marker glial fibrillary acidic protein (GFAP) are found in etiologically different neurological disorders affecting the peripheral and the central ne...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13118

    authors: Constantinescu R,Mahamud U,Constantinescu C,Eriksson B,Novakova L,Olsson B,Rosengren L,Blennow K,Axelsson M

    更新日期:2019-09-01 00:00:00

  • Hereditary spastic paraplegia with neurogenic bladder disturbances and syndactylia.

    abstract::The present paper reports a family settled in the northern part of Norway, with a hereditary neurological disorder consisting clinically of spastic paraplegia associated with neurogenic bladder disturbances and syndactylia. Nine out of 22 members in three generations exhibit these clinical features. The bladder distur...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb02993.x

    authors: Opjordsmoen S,Nyberg-Hansen R

    更新日期:1980-01-01 00:00:00

  • Acetazolamide effects on cerebral blood flow in acute reversible ischemia.

    abstract::Cerebral blood flow (CBF) was studied in 4 patients with acute reversible ischemia (RIND). To test the ischemic areas' vasoreactivity, CBF was measured by the Xenon-133 inhalation method, before and after acetazolamide injected intravenously. At the baseline CBF study, 3 patients presented hypoperfused areas while one...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03839.x

    authors: Di Piero V,Pozzilli C,Pantano P,Grasso MG,Fieschi C

    更新日期:1989-07-01 00:00:00

  • CTG repeat polymorphism in DMPK gene in healthy Yugoslav population.

    abstract:OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.00006.x

    authors: Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

    更新日期:2002-01-01 00:00:00

  • Astheno-emotional disorder after aneurysmal SAH: reliability, symptomatology and relation to outcome.

    abstract:OBJECTIVES:Neuropsychiatric symptoms commonly found after aneurysmal SAH are covered in the astheno-emotional disorder (AED) of Lindqvist & Malmgrens diagnostic system for organic psychiatry. This study aims to describe the reliability and symptomatology of AED and its relationship with social outcome. MATERIAL AND ME...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.103006379.x

    authors: Rödholm M,Starmark JE,Svensson E,Von Essen C

    更新日期:2001-06-01 00:00:00

  • A double-blind study of neurotropin in patients with acute ischemic stroke.

    abstract::Neurotropin was found to reduce brain oedema in an experimental model of brain infarction in the guinea-pig. A randomized double-blind controlled trial with Neurotropin was performed in 220 patients admitted within 24 h after an acute ischemic stroke. 35 of the neurotropin and 41 of the placebo-randomized patients had...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1994.tb02643.x

    authors: De Reuck J,Decoo D,Vanderdonckt P,Dallenga A,Ceusters W,Kalala JP,De Meulemeester K,Abdullah J,Santens P,Huybrechts J

    更新日期:1994-05-01 00:00:00

  • Utility of hospitalization following a first unprovoked seizure.

    abstract:OBJECTIVES:Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. MATERIALS AND METHODS:We...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12079

    authors: Goldberg I,Neufeld MY,Auriel E,Gandelman-Marton R

    更新日期:2013-07-01 00:00:00

  • Muscular cramps: proposals for a new classification.

    abstract::Muscle cramps are involuntary, painful, sudden contractions of the skeletal muscles. They are present in normal subjects under certain conditions (during a strong voluntary contraction, sleep, sports, pregnancy) and in several pathologies such as myopathies, neuropathies, motoneuron diseases, metabolic disorders, hydr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0404.2003.01289.x

    authors: Parisi L,Pierelli F,Amabile G,Valente G,Calandriello E,Fattapposta F,Rossi P,Serrao M

    更新日期:2003-03-01 00:00:00

  • Nicotinic α4β2 acetylcholine receptors and cognitive function in Parkinson's disease.

    abstract:BACKGROUND:Idiopathic Parkinson's disease (IPD) is characterized by the clinical motor symptoms of hypokinesia, rigidity, and tremor. Apart from these motor symptoms, cognitive deficits often occur in IPD. The positive effect of cholinesterase inhibitors on cognitive deficits in IPD and findings of earlier molecular im...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12259

    authors: Lorenz R,Samnick S,Dillmann U,Schiller M,Ong MF,Faßbender K,Buck A,Spiegel J

    更新日期:2014-09-01 00:00:00

  • Cerebrospinal fluid Flt3 ligand level in patients with amyotrophic lateral sclerosis.

    abstract:OBJECTIVES:The Flt3 ligand (FL) is a cytokine with a neurotrophic and antiapoptotic activity in the central nervous system that induces the survival of neurons. The aim of the study was to measure levels of FL in amyotrophic lateral sclerosis (ALS) patients. MATERIALS AND METHODS:The study involved 23 ALS patients and...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00704.x

    authors: Iłzecka J

    更新日期:2006-09-01 00:00:00

  • Immunological abnormalities in the tears of multiple sclerosis patients.

    abstract::IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb04034.x

    authors: Liedtke W,Weller M,Wiethölter H,Dichgans J

    更新日期:1992-03-01 00:00:00

  • Regional cerebral blood flow in various types of brain tumor. Effect of the space-occupying lesion on blood flow in brain tissue close to and remote from tumor site.

    abstract::Regional cerebral blood flow (rCBF) was measured in 23 patients with brain tumors using the 133Xe intra-carotid injection method and a 254 channel gamma camera. The glioblastomas (4) and astrocytomas (4) all showed hyperemia in the tumor and tumor-near region. This was also seen in several meningiomas (4 of 7 cases) i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1982.tb04513.x

    authors: Kuroda K,Skyhøj Olsen T,Lassen NA

    更新日期:1982-08-01 00:00:00

  • Epstein-Barr virus genotypes in multiple sclerosis.

    abstract:BACKGROUND:Multiple sclerosis (MS) is associated with Epstein-Barr virus (EBV) infection, but the relationship between the virus and the disease is not clear. As many different types of EBV exist, it is possible that MS is caused by one particular type of EBV. Objectives - The aim of this study was to determine whether...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2007.00917.x

    authors: Lindsey JW,Patel S,Zou J

    更新日期:2008-02-01 00:00:00

  • Concentrations of sulfur-containing free amino acids in lumbar cerebrospinal fluid from patients with consciousness disturbances.

    abstract::The concentrations of sulfur-containing amino acids (taurine, methionine, cystine, cystathionine, homocystine) in lumbar CSF from patients with consciousness disturbances and controls were measured, and it was investigated whether there was any correlation between the sequential changes of these amino acid concentrati...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1983.tb04848.x

    authors: Yanai Y,Shibasaki T,Kohno N,Mitsui T,Nakajima H

    更新日期:1983-12-01 00:00:00

  • EEG in presenile dementia related to cerebral blood flow and autopsy findings.

    abstract::EEG, regional cerebral blood flow (rCBF) and neuropathological autopsy data were studied in 17 patients with presenile dementia. RCBF was measured in 14 cases using the intra-arterial-133-Xenon clearance technique. The neuropathological study included semi-serial whole brain microscopical sections in which the severit...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1977.tb01414.x

    authors: Jóhannesson G,Brun A,Gustafson I,Ingvar DH

    更新日期:1977-08-01 00:00:00