Localized outbreak of enteroviral meningitis in adults.

Abstract:

:During a thorough surveillance of viral infections of the central nervous system an outbreak of aseptic meningitis was discovered in the western part of Finland in late 1985. The 21 diseased young adults were carefully studied by different virological methods. A presumed viral etiology, in all cases of enteroviral origin, was found in 16 of 20 (80%) with adequate specimens. Four different enteroviruses were associated with this episode; in 9 cases the presumed etiological agent was echovirus 5, while coxsackie B5, echo 25 and echo 17 viruses appeared to be responsible for 4, 2 and 1 case, respectively. Sensitivity of different diagnostic methods as regards detection of the echovirus 5 infections was in order: increase of type-specific neutralizing serum antibodies, isolation of virus from faeces, isolation from throat and group diagnosis by demonstrating an increase in complement-fixing antibodies to coxsackie B5 virus antigen.

journal_name

Acta Neurol Scand

authors

Kinnunen E,Hovi T,Stenvik M,Hellström O,Porras J,Kleemola M,Kantanen ML

doi

10.1111/j.1600-0404.1987.tb05457.x

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

346-51

issue

5

eissn

0001-6314

issn

1600-0404

journal_volume

75

pub_type

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