Abstract:
OBJECTIVES:We used an electrical conditioning stimulation followed by transcranial magnetic stimulation (TMS) to facilitate the occurrence of long latency potentials (LLPs) in order to study the relationship between primary motor evoked potentials (MEPs) and LLPs in the lower limbs. MATERIALS AND METHODS:The study group included 6 healthy subjects, 1 patient with right thalamic infarction, and 3 patients with spinal cord injuries. The subjects were subjected to electrical conditioning (C) stimulation delivered to the left big toe at 250 Hz in a train of pulses of 20 ms duration prior to TMS (T) from 0 to 150 ms at an increment of 10 ms. The surface electromyographic signals were recorded at the tibialis anterior and gastrocnemius medialis for 400 ms. RESULTS:The C-T test facilitated both primary MEPs and LLPs with a pattern similar to the primary MEPs of its antagonist. There was no facilitation of the primary MEPs or LLPs in the affected limb of patients with thalamic or spinal cord lesions. CONCLUSION:At appropriate C-T interval, LLPs could be consistently provoked by TMS. The LLPs were absent in the patients with thalamic infarction and spinal cord injuries. It suggests that LLPs might be provoked through a supraspinal control.
journal_name
Acta Neurol Scandjournal_title
Acta neurologica Scandinavicaauthors
Chen JT,Chen CC,Kao KP,Wu ZA,Liao KKdoi
10.1111/j.1600-0404.1998.tb07323.xsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
412-21issue
6eissn
0001-6314issn
1600-0404journal_volume
98pub_type
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journal_title:Acta neurologica Scandinavica
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更新日期:2013-07-01 00:00:00
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更新日期:2016-01-01 00:00:00