Quality of life in chronic inflammatory demyelinating polyneuropathy patients treated with subcutaneous immunoglobulin.

Abstract:

BACKGROUND:Subcutaneous immunoglobulin (SCIG) is effective treatment of chronic inflammatory demyelinating polyneuropathy (CIDP). Quality of life (QoL) increases following switch from intravenous administration to SCIG, but its correlation with clinical functioning is sparsely studied. AIMS OF THE STUDY:The aim of this study is to evaluate the correlation between QoL and clinical functioning in CIDP patients treated with SCIG. METHODS:Danish patients with CIDP with a disease duration <10 years and currently treated with SCIG were eligible for inclusion. QoL was assessed with EQ-5D-5L and disability by the Overall Disability Sum Score (ODSS) and Rasch-built Overall Disability Scale (RODS). Gait performance was evaluated by a 40-meter-walk test (40-MWT) and a 6-spot-step test (6-SST) along with assessment of muscle strength (Medical Research Council score [MRC]). Correlations between QoL and the measured scores were calculated. RESULTS:Of 92 eligible patients, 44 were included. QoL on the visual analogue scale (VAS) was 65% (range: 15-90) of the level of healthy controls (P = .03) and correlated to impaired gait function by 40-MWT and 6-SST. QoL correlated to RODS and ODSS, whereas there was no correlation with the MRC score. CONCLUSIONS:In SCIG treated CIDP patients QoL is reduced and correlates to gait performance and disability.

journal_name

Acta Neurol Scand

authors

Ryltoft AK,Al-Zuhairy A,Sindrup SH,Andersen H,Markvardsen LK

doi

10.1111/ane.13322

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

637-640

issue

6

eissn

0001-6314

issn

1600-0404

journal_volume

142

pub_type

杂志文章
  • Treatment of tardive dyskinesia with levetiracetam in a transplant patient.

    abstract:OBJECTIVE:To describe successful treatment of tardive dyskinesia with levetiracetam. BACKGROUND:Tardive dyskinesia is a late-onset movement disorder caused by exposure to dopamine receptor blocking agents, most commonly neuroleptics. Metoclopramide is frequently used to treat gastrointestinal dysmotility. It has antid...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2007.00950.x

    authors: Zivković SA,Costa G,Bond G,Abu-Elmagd KM

    更新日期:2008-05-01 00:00:00

  • Is there a lamotrigine withdrawal syndrome?

    abstract:OBJECTIVES:To report a peculiar observation of a patient who developed a psychomotor inhibition state after a rapid cessation of lamotrigine (LTG). RESULTS:This man was referred to us at the age of 26 years for presurgical evaluation. His treatment [valproate (VPA), 1200 mg/day and LTG, 200 mg/day] was quickly decreas...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.1c220.x

    authors: Gelisse P,Kissani N,Crespel A,Jafari H,Baldy-Moulinier M

    更新日期:2002-03-01 00:00:00

  • M-wave analysis and passive tilt in patients with different degrees of carotid artery disease.

    abstract:BACKGROUND AND PURPOSE:Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00210.x

    authors: Haubrich C,Klemm A,Diehl RR,Möller-Hartmann W,Klötzsch C

    更新日期:2004-03-01 00:00:00

  • Temporal lobe epilepsy visualized with PET with 11C-L-deuterium-deprenyl--analysis of kinetic data.

    abstract:OBJECTIVES:The purpose of the study was to develop a simplified method for the acquisition and analysis of data from positron emission tomography (PET) using the ligand 11C-L-deuterium-deprenyl. This is motivated by an increased interest in methods to characterize gliosis in neurodegenerative diseases and epilepsy, whi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1998.tb07300.x

    authors: Bergström M,Kumlien E,Lilja A,Tyrefors N,Westerberg G,Långström B

    更新日期:1998-10-01 00:00:00

  • Natural anticoagulants (antithrombin III, protein C, and protein S) in patients with mild to moderate ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:The role of the natural anticoagulants, antithrombin III (AT III), protein C (PC), and protein S (PS), in patients with mild to moderate ischemic stroke remains uncertain. We aimed to find out whether their levels in peripheral blood correlated with the severity of neurological deficit or can pre...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.1o112.x

    authors: Haapaniemi E,Tatlisumak T,Soinne L,Syrjälä M,Kaste M

    更新日期:2002-02-01 00:00:00

  • Pneumoencephalographic and clinical characteristics of diffuse cerebral atrophy.

    abstract::The clinical features in 268 patients with diffuse cerebral atrophy of initially unknown origin have been analysed. Pneumoencephalography showed supratentorial ventricular atrophy in 87 per cent (cortical in 71 per cent), and brain stem and/or cerebellar atrophy in 17 per cent of the patients. Epileptic seizures, dizz...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1975.tb01372.x

    authors: Iivanainen M

    更新日期:1975-04-01 00:00:00

  • Vitamin D and multiple sclerosis—from epidemiology to prevention.

    abstract::In the present review, we discuss observational and experimental data suggesting a protective effect from sun exposure and/or vitamin D in multiple sclerosis (MS). These data include geographic variations in MS occurrence, temporal trends, genetics, biobank, and questionnaire data. We look more closely at the differen...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/ane.12432

    authors: Sundström P,Salzer J

    更新日期:2015-01-01 00:00:00

  • Pre-traumatic conditions can influence cortisol levels before and after a brain injury.

    abstract:OBJECTIVE:Satisfactory anabolic reactions, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, are essential following severe traumatic brain injury (TBI) and aneurysmal subarachnoid hemorrhage (SAH). Many factors may influence this activation. This study aimed to investigate whether individuals ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13212

    authors: Sörbo A,Eiving I,Theodorsson E,Rydenhag B,Jonsdottir IH

    更新日期:2020-04-01 00:00:00

  • Benign muscular dystrophy with contractures: a new syndrome?

    abstract::Three patients are described with muscular dystrophy and contractures. Although this disorder bears similarities to Emery-Dreifuss disease and variants previously described, absence of cardiomyopathy is a distinguishing feature. Electrodiagnostic testing and muscle biopsy are consistent with a myopathy. An autosomal d...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb03302.x

    authors: Bailey RO,Dentinger MP,Toms ME,Hans MB

    更新日期:1986-04-01 00:00:00

  • EEG findings in diabetic patients with and without retinopathy.

    abstract:OBJECTIVES:We showed previously that temporal low-voltage irregular delta waves (TLID) on EEG are indicative of cerebrovascular dysfunction in its early stages. The present study was designed to determine whether the incidence of this finding is elevated in diabetics as compared to normal controls. METHODS:EEGs of 50 ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1998.tb00618.x

    authors: Inui K,Sannan H,Ota H,Uji Y,Nomura S,Kaige H,Kitayama I,Nomura J

    更新日期:1998-02-01 00:00:00

  • How broad is the phenotype of Hallervorden-Spatz disease?

    abstract::Magnetic resonance imaging (MRI) has enabled ante mortem diagnosis of Hallervorden Spatz disease (HSD). Childhood-onset cases are the most common type and usually present with progressive dystonia and dementia. The duration of illness is 15 to 20 years, leading to death. Presentation in adulthood and infancy have also...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.103003201.x

    authors: Hickman SJ,Ward NS,Surtees RA,Stevens JM,Farmer SF

    更新日期:2001-03-01 00:00:00

  • Visually evoked potentials in respiratory chain disorders.

    abstract:OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.00167.x

    authors: Finsterer J

    更新日期:2001-07-01 00:00:00

  • Stroke before 55 years of age at Karolinska Hospital 1973-77. A study of 399 well-defined cases. Risk indicators and etiological considerations.

    abstract::The etiological characteristics of cerebrovascular disease (CVD) before the age of 55 are reviewed in 399 patients admitted to the Department of Neurology, Karolinska Hospital, Stockholm, from 1973-77. The material was well-defined with regard to subtypes of stroke as well as to the diseased population. The control ma...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1984.tb00846.x

    authors: Mettinger KL,Söderström CE,Neiman J

    更新日期:1984-12-01 00:00:00

  • Neuropathy and impaired glucose tolerance: an updated review of the evidence.

    abstract::There has been considerable interest in the possible association between impaired glucose tolerance (IGT) and neuropathy. A systematic literature search (Medline) and review was here performed. Twenty-three studies were evaluated. Fourteen investigated for the presence of neuropathy in patients with IGT. Nine studied ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0404.2010.01425.x

    authors: Rajabally YA

    更新日期:2011-07-01 00:00:00

  • Serum-soluble receptor for advanced glycation end product levels in patients with amyotrophic lateral sclerosis.

    abstract:OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. There is evidence that oxidative stress is implicated in the pathophysiology of the neurodegenerative disorders, including ALS. Data from the literature suggests that the receptor for advanced glycation end products (RAGE) partic...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2008.01133.x

    authors: Iłzecka J

    更新日期:2009-08-01 00:00:00

  • Depression in the early phase of MS: influence of functional disability, cognitive impairment and brain abnormalities.

    abstract::This study investigated the relationship between depression, physical disability, cognitive deficit and brain abnormalities on magnetic resonance imaging (MRI) in patients with early MS. Eighteen relapsing-remitting MS patients were evaluated: depression was diagnosed according to DSM-III R and measured by the MMPI de...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05100.x

    authors: Millefiorini E,Padovani A,Pozzilli C,Loriedo C,Bastianello S,Buttinelli C,Di Piero V,Fieschi C

    更新日期:1992-10-01 00:00:00

  • Otoneurological abnormalities in asymptomatic HIV-seropositive patients.

    abstract::Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03726.x

    authors: Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

    更新日期:1989-02-01 00:00:00

  • Autoimmune diseases in families of French patients with multiple sclerosis.

    abstract::Multiple sclerosis (MS) is associated with autoimmune disorders (AIDs) in individual patients, and limited data suggest a possible familial association of MS and AIDs; however, no systematic study has been conducted on the occurrence of AIDs in the families of MS patients. Using a standardized interview focused on AID...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2000.101001036.x

    authors: Heinzlef O,Alamowitch S,Sazdovitch V,Chillet P,Joutel A,Tournier-Lasserve E,Roullet E

    更新日期:2000-01-01 00:00:00

  • Cerebrospinal neuron-specific enolase, S-100 and myelin basic protein in neurological disorders.

    abstract::In this study levels of neuron-specific enolase (NSE), S-100 protein (S-100) and myelin basic protein (MBP) in cerebrospinal fluid (CSF) of children and adults with distinct neurological disorders were examined. A previous study from our department demonstrated age related reference values for these brain-specific pro...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb01696.x

    authors: Lamers KJ,van Engelen BG,Gabreëls FJ,Hommes OR,Borm GF,Wevers RA

    更新日期:1995-09-01 00:00:00

  • Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome.

    abstract:OBJECTIVE:To determine whether variants in the Slit and Trk-like 1 gene (SLITRK1) are present in American Caucasian population of patients with Tourette syndrome (TS). METHODS:We sequenced the 3'-untranslated region for var321 and the whole coding region in the SLITRK1 gene in 82 Caucasian patients with TS from North ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00706.x

    authors: Deng H,Le WD,Xie WJ,Jankovic J

    更新日期:2006-12-01 00:00:00

  • Determinants of post-stroke cognitive impairment: analysis from VISTA.

    abstract:BACKGROUND:Post-stroke cognitive impairment (PSCI) occurs commonly and is linked with development of dementia. We investigated the relationship between demographic, clinical and stroke symptoms at stroke onset and the presence of PSCI at 1 and 3 years after stroke. METHODS:We accessed anonymized data from the Virtual ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12637

    authors: Arba F,Quinn T,Hankey GJ,Inzitari D,Ali M,Lees KR,VISTA Collaboration.

    更新日期:2017-06-01 00:00:00

  • Plantar stimulation alters brain connectivity in idiopathic Parkinson's disease.

    abstract:OBJECTIVE:Individuals with Parkinson's disease (PD) and freezing of gait (FOG) present peripheral and central sensitivity disturbances that impair motor performance. This study aimed to investigate long-term effects of plantar sensory stimulation on brain activity, brain connectivity, and gait velocity of individuals w...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ane.13253

    authors: Pagnussat AS,Salazar AP,Pinto C,Redivo Marchese R,Rieder CRM,Alves Filho JO,Franco AR,Kleiner AFR

    更新日期:2020-09-01 00:00:00

  • Brain morphology in juvenile myoclonic epilepsy and absence seizures.

    abstract:OBJECTIVE:We evaluated the differences in brain morphology among patients with juvenile myoclonic epilepsy according to the occurrence of absence seizures. MATERIALS AND METHODS:Twenty-one juvenile myoclonic epilepsy patients with (n = 6) and without (n = 15) absence seizures were enrolled. We analyzed whole-brain T1-...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12436

    authors: Park KM,Kim TH,Han YH,Mun CW,Shin KJ,Ha SY,Park JS,Kim SE

    更新日期:2016-02-01 00:00:00

  • Psychomotor dysfunctions in alcoholic and post-necrotic cirrhotic patients without overt encephalopathy.

    abstract::Psychometric tests, visual reaction time tests and electroencephalograms were performed in 26 cirrhotic patients without overt portal-systemic encephalopathy and in 26 healthy individuals. Cirrhotics performed poorly, compared with controls, on intelligence, learning and memory, perceptual motor and spatial tests. Non...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03785.x

    authors: Puca FM,Antonaci F,Panella C,Guglielmi FW,Barone M,Francavilla A,Cerutti R

    更新日期:1989-04-01 00:00:00

  • The epidemiology of post-stroke epilepsy according to stroke subtypes.

    abstract:OBJECTIVES:Strokes represent the most common etiology of epilepsy in patients over the age of 60 years, with an incidence of 2-4% occurring in different studies. MATERIALS AND METHODS:In this observational study, 1,428 patients were included who had stroke and were admitted to our Stroke Unit between the years 1996 an...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00642.x

    authors: Benbir G,Ince B,Bozluolcay M

    更新日期:2006-07-01 00:00:00

  • Transcranial Doppler echo contrast studies using different colour processing modes.

    abstract:OBJECTIVES:To study the effects of different colour imaging modes on the contrast-medium-enhanced image of the intracranial cerebral arteries. METHODS:Twelve healthy volunteers were studied transcranially after administration of 10 ml BY963 successively with Power Doppler (p-TCCS) and with colour Doppler frequency ima...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1997.tb00225.x

    authors: Kaps M,Schaffer P,Beller KD,Seidel G,Wurst W

    更新日期:1997-06-01 00:00:00

  • Parkinson syndrome as a manifestation of mitochondriopathy.

    abstract:OBJECTIVES:Although there is growing evidence for a relation between Parkinson syndrome (PS) and mitochondriopathy (MCP), little is known about the frequency of PS in MCP. MATERIAL AND METHODS:This study assessed the frequency of PS in patients with MCP, the phenotype of these patients, and their response to anti-Park...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.01221.x

    authors: Finsterer J

    更新日期:2002-05-01 00:00:00

  • Enteric-coated acetylsalicylic acid plus dipyridamole compared with anticoagulants in the prevention of ischemic events in patients with transient ischemic attacks.

    abstract::From December 1976 through March 1982, 188 patients entered an open non-random study carried out on hospitalized patients with a history of transient ischemic attacks or amaurosis fugax. Ninety-two patients received peroral anticoagulants usually combined with heparin treatment during the first days of treatment, and ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb03232.x

    authors: Eriksson SE

    更新日期:1985-06-01 00:00:00

  • Vaccine-associated contact paralytic poliomyelitis with atypical neurological presentation.

    abstract::Paralytic poliomyelitis presenting with quadriparesis, transient encephalitis and bulbar symptoms in 2 patients in close contact with recently vaccinated children with trivalent live oral polio vaccine is described. Symmetrical lower motor neuron involvement of deltoid muscles with electromyographic confirmation was f...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb03569.x

    authors: Arlazoroff A,Bleicher Z,Klein C,Vure E,Lahat E,Gross B,Handsher R

    更新日期:1987-09-01 00:00:00

  • "Numb, clumsy hands" and tactile agnosia secondary to high cervical spondylotic myelopathy: a clinical and electrophysiological correlation.

    abstract::Four patients presented with a distinctive syndrome of "numb, clumsy hand" and tactile agnosia. Myelography and computed tomographic myelography (CTM) of the cervical spine documented major spondylotic compressive lesions mainly between the C3 and C5 levels. The cortical responses of dermatomal somatosensory evoked po...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05499.x

    authors: Chang MH,Liao KK,Cheung SC,Kong KW,Chang SP

    更新日期:1992-12-01 00:00:00