Epidemiological characteristics of motor neuron disease in Chinese patients.

Abstract:

BACKGROUND:The epidemiology, diagnosis, and treatment of motor neuron disease (MND) in Chinese patients are ill known. METHODS:A registered study of 461 MND patients was conducted across 10 facilities in 7 Chinese cities from February 2009 to March 2010. RESULTS:Patients were classified as amyotrophic lateral sclerosis (ALS) (84.4%), progressive bulbar palsy (PBP) (4.1%), progressive muscular atrophy (PMA) (10.4%), or primary lateral sclerosis (PLS) (0.9%). MND was predominant in men (men/women; 1.6:1.0). Mean onset age was 52.6 years, with the highest incidence being observed between 51 and 60 years. Notably, 26.0% of MND patients were employed in forestry, fishery, or animal husbandry industries. Ten cases (2.7%) reported family history of MND, and 54.2% exhibited cervical onset. MND was also associated with head/neck trauma. Non-invasive positive pressure ventilation was the most common supportive therapy. CONCLUSION:As a novel comprehensive report of a Chinese population, this study reveals that epidemiological characteristics of MND patients were similar to those observed in international populations. MND is age-related, male gender predominant, and may be associated with both environmental and genetic risk factors.

journal_name

Acta Neurol Scand

authors

Cui F,Liu M,Chen Y,Huang X,Cui L,Fan D,Pu C,Lu J,Zhou D,Zhang C,Yan C,Li C,Ding X,Liu Y,Li X,Jiang Y,Zhang J,Shang H,Yao X,Ding Y,Niu Q,Wang L

doi

10.1111/ane.12240

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

111-7

issue

2

eissn

0001-6314

issn

1600-0404

journal_volume

130

pub_type

杂志文章,多中心研究
  • The controversy of birth order as a risk factor for epilepsy: a study from Saudi Arabia.

    abstract:PURPOSE:To evaluate the relationship between people with epilepsy and birth order. METHODS:A case-control study of 336 epileptics, 15 years and above, and their 1961 full siblings. The data was analysed by birth order and then stratified by sibship size. The 95% confidence interval (CI) for each odds ratio (OR) was ob...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.1o142.x

    authors: Obeid T,Awada A,Amene P,Oni G

    更新日期:2002-03-01 00:00:00

  • Cerebrospinal fluid biomarkers in patients with neurological symptoms but without neurological diseases.

    abstract:BACKGROUND:Elevated levels of the cerebrospinal fluid (CSF) neuronal injury markers (neurofilament light chain [NF-L] and total tau protein [t-tau]) and of the astroglial marker glial fibrillary acidic protein (GFAP) are found in etiologically different neurological disorders affecting the peripheral and the central ne...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13118

    authors: Constantinescu R,Mahamud U,Constantinescu C,Eriksson B,Novakova L,Olsson B,Rosengren L,Blennow K,Axelsson M

    更新日期:2019-09-01 00:00:00

  • Influence of carbamazepine on serum thyroxine and triiodothyronine in patients with epilepsy.

    abstract::Hypothyroidism induced by anti-epileptic drug treatment gave rise to thyroid function test studies in patients treated with carbamazepine (CBZ) only. In 42 patients on long-term CBZ treatment thyroxine (T4), free T4-index (FT4I), and triiodothyronine (T3) concentrations in serum were significantly lower than in contro...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1981.tb00754.x

    authors: Strandjord RE,Aanderud S,Myking OL,Johannessen SI

    更新日期:1981-02-01 00:00:00

  • Different patterns of CSF neurotransmitter metabolism in patients with left or right hemispheric stroke.

    abstract::In 30 ischemic stroke patients, divided into 2 groups depending on the side of their hemispheric cerebral lesion, the authors evaluated the levels of CSF homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA). The changes of these metabolites in CSF samples collected 3, 14 and 25 days after stroke have been c...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb04603.x

    authors: Ferrarese C,Bassi S,Frattola L,Locatelli P,Piolti R,Trabucchi M

    更新日期:1986-06-01 00:00:00

  • Inhibitory effect of unsaturated fatty acids on lymphocyte-antigen interaction with special reference to multiple sclerosis.

    abstract::Using the macrophage electrophoretic mobility (MEM) test, the in vitro effects of oleic, linoleic and arachidonic acid, as well as Naudicell oil and methyl gamma-linolenate, on lymphocyte response to various antigens (PPD, thyroid antigen and EF) were studied in patients with mutiple sclerosis, patients with other neu...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1975.tb05766.x

    authors: Field EJ,Shenton BK

    更新日期:1975-08-01 00:00:00

  • F wave studies after intrathecal methotrexate administration.

    abstract::Electrophysiological examinations were done on 20 patients aged 40-71 years with recently diagnosed high grade non-Hodgkin's lymphomas. General chemotherapy and intrathecal chemotherapy in order to prevent central nervous system (CNS) involvement were begun. On the first day of chemotherapeutic cycle patients received...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb07065.x

    authors: Grzelec H,Fryze C,Nowacki P,Zdziarska B

    更新日期:1996-10-01 00:00:00

  • Antiepileptic drugs, foetal malformations and spontaneous abortions.

    abstract:BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12672

    authors: Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

    更新日期:2017-03-01 00:00:00

  • Efficacy and safety of rituximab in autoimmune encephalitis: A meta-analysis.

    abstract:BACKGROUND:Autoimmune encephalitis (AE) is a rare but debilitating neurological disease where the body develops antibodies against neuronal cell surface/synaptic proteins. Rituximab is an anti-CD20 chimeric monoclonal antibody which shows promise in AE treatment observational studies. To our knowledge, there has been n...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ane.13291

    authors: Nepal G,Shing YK,Yadav JK,Rehrig JH,Ojha R,Huang DY,Gajurel BP

    更新日期:2020-11-01 00:00:00

  • Assessment of the ophthalmic artery as a collateral to the cerebral circulation. A comparison of transorbital Doppler ultrasonography and regional cerebral blood flow measurements.

    abstract::The role of the ophthalmic artery (OA) as a collateral to the cerebral circulation in carotid occlusive disease is somewhat controversial. The aim of this study was to assess the importance of this collateral by comparing the results of transorbital Doppler ultrasonography and regional cerebral blood flow measurements...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb00012.x

    authors: Kerty E,Nyberg-Hansen R,Dahl A,Bakke SJ,Russell D,Rootwelt K

    更新日期:1996-05-01 00:00:00

  • Rising mortality from Parkinson's disease in Japan, 1950-1992.

    abstract::The death rate from Parkinson's disease (PD) were analyzed using Japanese vital statistics for 1950-1992. The age-adjusted PD death rate increased statistically significantly with the years between 1950 and 1992 for both sexes. However, decline in the PD death rate were observed among the population under 65 years old...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb00428.x

    authors: Imaizumi Y,Kaneko R

    更新日期:1995-03-01 00:00:00

  • Prevalence of lumbosacral radiculopathy in two Sicilian municipalities. Sicilian Neuro-Epidemiologic Study (SNES) Group.

    abstract:OBJECTIVES:As part of a door-to-door survey of neurologic diseases, we investigated the prevalence of lumbosacral radiculopathy (LR) in two Sicilian municipalities (N = 14,540, as of November 1, 1987). MATERIAL & METHODS:During phase 1, we administered a brief screening instrument to subjects in the study population. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb00027.x

    authors: Savettieri G,Salemi G,Rocca WA,Meneghini F,D'Arpa A,Morgante L,Coraci MA,Reggio A,Grigoletto F,Di Perri R

    更新日期:1996-06-01 00:00:00

  • Pharmacological studies of the uninhibited neurogenic bladder. I. The influence of repeated filling and various filling rates on the cystometrogram of neurological patients with normal and uninhibited neurogenic bladder.

    abstract::The influence on the cystometrogram of repeated filling and varying filling rates was studied in two groups of neurological patients, one with normal and one with uninhibited neurogenic bladder. A technique which permits an even bladder filling and a continuous recording of the intravesical pressure was used. The effe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Jensen D Jr

    更新日期:1981-09-01 00:00:00

  • Abnormalities of mitochondrial enzymes in hereditary ataxias.

    abstract::The activity of 7 mitochondrial enzymes, fumarase, NAD-malate dehydrogenase (MDH), citrate synthase (CS), valine dehydrogenase (VDH), succinate dehydrogenase (SDH), glutamate dehydrogenase (GDH), pyruvate dehydrogenase complex (PDHC) has been measured in platelet preparations from patients affected by Friedreich's ata...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03849.x

    authors: Sorbi S,Piacentini S,Fani C,Tonini S,Marini P,Amaducci L

    更新日期:1989-08-01 00:00:00

  • Depression in the early phase of MS: influence of functional disability, cognitive impairment and brain abnormalities.

    abstract::This study investigated the relationship between depression, physical disability, cognitive deficit and brain abnormalities on magnetic resonance imaging (MRI) in patients with early MS. Eighteen relapsing-remitting MS patients were evaluated: depression was diagnosed according to DSM-III R and measured by the MMPI de...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05100.x

    authors: Millefiorini E,Padovani A,Pozzilli C,Loriedo C,Bastianello S,Buttinelli C,Di Piero V,Fieschi C

    更新日期:1992-10-01 00:00:00

  • Quality of life in newly-debuted epilepsy. An empirical study.

    abstract:OBJECTIVES:This study aimed to illuminate adult's experienced quality of life in newly-debuted epilepsy and to test the American instrument Quality of Life Index (QLI) for the first time on an epilepsy population. A second aim was to find appropriate questions to measure patient perceptions in epilepsy. MATERIAL AND M...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb00384.x

    authors: Räty L,Hamrin E,Söderfeldt B

    更新日期:1999-10-01 00:00:00

  • Abnormalities of T-lymphocyte subsets in epileptic patients.

    abstract::This study concerns the distribution of T-cell subsets as determined by specific monoclonal antibodies in 50 individuals with complex partial seizures (31) and primary generalized tonic-clonic seizures (19), and in 30 healthy controls. The epileptic group had significantly fewer circulating T4 "helper" lymphocytes and...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb00855.x

    authors: Eeg-Olofsson O,Prchal JF,Andermann F

    更新日期:1985-08-01 00:00:00

  • Left ventricular failure and pulmonary edema in acute multiple sclerosis.

    abstract::We describe a young woman who developed left ventricular failure and pulmonary edema during fulminant onset of multiple sclerosis. One of the numerous plaques was located in the left inferior cerebellar peduncle near the dorsal motor vagal and solitary tract nuclei. Within two days pulmonary edema had cleared, and wit...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb00002.x

    authors: Melin J,Usenius JP,Fogelholm R

    更新日期:1996-05-01 00:00:00

  • Haplotype analysis of the DM1 locus in the Serbian population.

    abstract:OBJECTIVES:Analysis of the CTG-repeat number and three biallelic markers, Alu(+/-), HinfI(+/-), and TaqI(+/-), in the DMPK gene in healthy and myotonic dystrophy type 1 (DM1) Serbian individuals. Also, the consideration of haplotypes in the light of the proposed models of CTG-repeat evolution and origin of the DM1 muta...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2005.00402.x

    authors: Krndija D,Savić D,Mladenović J,Rakocević-Stojanović V,Apostolski S,Todorović S,Romac S

    更新日期:2005-04-01 00:00:00

  • Juvenile neurolipidosis of Bernheimer-Seitelberger's type. Histopathological and biochemical findings.

    abstract::Two children are reported, who became diseased at the age of 4 and 2 years, respectively, with progressive upper motor neuron symptoms leading to severe disability within a few years. The boy died at age 10 and autopsy disclosed a severe gangliolipidosis throughout the central nervous system, maximal in the brain stem...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1977.tb01464.x

    authors: Brandt S,Clausen J,Diemer NH,Faurholt-Pedersen V,Jensen GE,Lademann A,Melchior JC

    更新日期:1977-12-01 00:00:00

  • Leber's hereditary optic neuropathy associated with a disorder indistinguishable from multiple sclerosis in a male harbouring the mitochondrial DNA 11778 mutation.

    abstract::This report describes a multiple sclerosis (MS)-like disorder in a male patient with Leber's hereditary optic neuropathy (LHON) harbouring the mitochondrial DNA 11778 base pair mutation. Given the population frequencies of MS and LHON, coincidental occurrence is unlikely. Hypothetically the mitochondrial mutation unde...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb07016.x

    authors: Olsen NK,Hansen AW,Nørby S,Edal AL,Jørgensen JR,Rosenberg T

    更新日期:1995-05-01 00:00:00

  • Comparison of upright balance in stroke, Parkinson and multiple sclerosis.

    abstract:OBJECTIVE:Multiple sclerosis (MS), Parkinson's disease (PD) and stroke (ST) subjects show balance impairments due to damage of the balance control system. The objective of the study was to assess the impact of MS, PD and ST on upright posture in eyes open condition and when visual and/or proprioceptive inputs are alter...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12466

    authors: Cattaneo D,Carpinella I,Aprile I,Prosperini L,Montesano A,Jonsdottir J

    更新日期:2016-05-01 00:00:00

  • Hip fracture after first-ever stroke: a population-based study.

    abstract:OBJECTIVES:The aim of this study is to estimate the risk of hip fracture after first-ever stroke, using a nationwide population-base data set and a retrospective cohort design. MATERIALS AND METHODS:The cohort study involved 18,413 patients surviving a first-ever stroke during the 12-year period from 1997 to 2008. Ano...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12301

    authors: Lin HL,Lin HC,Tseng YF,Liao HH,Worly JA,Pan CY,Hsu CY

    更新日期:2015-03-01 00:00:00

  • CTG repeat polymorphism in DMPK gene in healthy Yugoslav population.

    abstract:OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.00006.x

    authors: Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

    更新日期:2002-01-01 00:00:00

  • Subthalamic deep brain stimulation and trunk posture in Parkinson's disease.

    abstract:OBJECTIVES:We sought to assess the efficacy of subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD)-associated trunk posture abnormalities retrospectively analyzing data from 101 patients reporting mild-to-severe trunk posture abnormalities of a cohort of 216 PD patients treated with STN-DBS...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12889

    authors: Artusi CA,Zibetti M,Romagnolo A,Rizzone MG,Merola A,Lopiano L

    更新日期:2018-05-01 00:00:00

  • Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type.

    abstract::The possibility of disturbed dopamine and serotonin metabolism in senile dementia of Alzheimer type was studied. The basal concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) were studied in 28 patients with senile dementia of Alzheimer type and in 13 controls...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1981.tb04392.x

    authors: Soininen H,MacDonald E,Rekonen M,Riekkinen PJ

    更新日期:1981-08-01 00:00:00

  • A large Japanese family with Machado-Joseph disease: clinical and genetic studies.

    abstract::A large Japanese family with probable Machado-Joseph disease (MJD) is described. Detailed neurological examination in 12 patients from 3 generations revealed variable combinations of cerebellar ataxia, ocular paresis, difficulty in eye-lid opening, bulging eyes, facial "myokymia", facial dystonia, pyramidal signs, ext...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03741.x

    authors: Takiyama Y,Ikemoto S,Tanaka Y,Mizuno Y,Yoshida M,Yasuda N

    更新日期:1989-03-01 00:00:00

  • Season of birth and multiple sclerosis in Sweden.

    abstract:OBJECTIVE:To estimate the risk of multiple sclerosis (MS) by month of birth in Sweden. MATERIALS AND METHODS:Cases (n = 9361) were obtained from the Swedish MS Registry. All births in Sweden 1900-2007 served as controls (n = 12,116,853). The risk of MS was analyzed for each month of birth separately compared with birt...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01181.x

    authors: Salzer J,Svenningsson A,Sundström P

    更新日期:2010-01-01 00:00:00

  • Migraine without aura: comparison with cervicogenic headache. Vågå study of headache epidemiology.

    abstract:OBJECTIVES:To study migraine without aura (MwoA) prevalence in the commune of Vågå, Norway; 1838 (18- to 65-year-old) individuals were included. A special search was made for cervicogenic characteristics in MwoA, as it has been claimed that such characteristics may frequently be present. A comparison with cervicogenic ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2007.00966.x

    authors: Sjaastad O,Bakketeig LS

    更新日期:2008-06-01 00:00:00

  • Clinical features of multiple sclerosis in north-east Scotland.

    abstract::The clinical features of multiple sclerosis (MS) in north-east Scotland have been examined along with an epidemiological study to determine the prevalence of the disease on 1st December, 1970. Patient information was collected from all available diagnostic indices, both retrospectively and prospectively from 1965. Eve...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1979.tb02973.x

    authors: Shepherd DI

    更新日期:1979-10-01 00:00:00

  • Astheno-emotional disorder after aneurysmal SAH: reliability, symptomatology and relation to outcome.

    abstract:OBJECTIVES:Neuropsychiatric symptoms commonly found after aneurysmal SAH are covered in the astheno-emotional disorder (AED) of Lindqvist & Malmgrens diagnostic system for organic psychiatry. This study aims to describe the reliability and symptomatology of AED and its relationship with social outcome. MATERIAL AND ME...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.103006379.x

    authors: Rödholm M,Starmark JE,Svensson E,Von Essen C

    更新日期:2001-06-01 00:00:00