Predictive value of fibronectin levels in normotensive gravid women destined to become preeclamptic.

Abstract:

:The plasma fibronectin concentration was abnormally elevated (greater than 400 micrograms/ml) in 16 of 17 normotensive gravid women who subsequently developed preeclampsia. Of this group, 13 had elevated levels detectable greater than or equal to 4 weeks before the onset of hypertension. Our results indicate that plasma fibronectin levels can be abnormally increased long before the onset of clinical symptoms and that abnormalities of this glycoprotein may be an early indication of this pathologic process.

journal_name

Am J Obstet Gynecol

authors

Lazarchick J,Stubbs TM,Romein L,Van Dorsten JP,Loadholt CB

doi

10.1016/0002-9378(86)90748-9

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

1050-2

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(86)90748-9

journal_volume

154

pub_type

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