Conjugal transfer of hydrogen-oxidizing ability of Alcaligenes hydrogenophilus to Pseudomonas oxalaticus.

abstract：:We hypothesized that the mutational strand asymmetry is more strongly exerted upon the mitochondrial cytochrome b (Cytb) gene, which is distant from the origin of the light-strand replication (Ori(L)), than upon the ATPase subunit 6 (ATP6) gene, which is close to the Ori(L). To test this hypothesis, we determined the ...

journal_title：Biochemical and biophysical research communications

authors： Fuku N,Oshida Y,Takeyasu T,Guo LJ,Kurata M,Yamada Y,Sato Y,Tanaka M

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Recently, it has been reported that hypoxia highly enhances expression of peptidylarginine deiminase (PAD) 4 and production of citrullinated proteins in some tumor cells. However, little is known about malignant gliomas on this issue. Therefore, we here investigated whether expression of PADs was induced by ...

journal_title：Biochemical and biophysical research communications

authors： Sase T,Arito M,Onodera H,Omoteyama K,Kurokawa MS,Kagami Y,Ishigami A,Tanaka Y,Kato T

更新日期：2017-01-01 00:00:00

abstract：:Mangosteen, a fruit mainly produced in Southeast Asia, has been used as food and as an antipyretic and for treating skin diseases. The xanthones contained in mangosteen have many physiological activities including melanin suppression and anticancer activities, but little is known about the physiological effects of the...

journal_title：Biochemical and biophysical research communications

authors： Lin M,Zhou S,Sakamoto K

更新日期：2020-07-12 00:00:00

abstract：:Antisense activity in living cells has been thought to occur via a mechanism involving both DNA-mediated hybridization arrest of target mRNA and RNase H-mediated mRNA digestion. Therefore an ideal antisense agent should be permeable to the cell and possess capacities (1) to form a thermally stable duplex in vivo with ...

journal_title：Biochemical and biophysical research communications

authors： Matsukura M,Okamoto T,Miike T,Sawai H,Shinozuka K

更新日期：2002-05-24 00:00:00

abstract：:The change of transferrin receptors in regenerating rat liver cells after partial hepatectomy was demonstrated. The binding of 125I-labeled transferrin to the cells began to increase after 24 h of partial hepatectomy and reached about double that of the non-operated normal rat liver cells. A Scatchard analysis of bind...

journal_title：Biochemical and biophysical research communications

authors： Tei I,Makino Y,Kadofuku T,Kanamaru I,Konno K

更新日期：1984-06-15 00:00:00

abstract：:The codon-reading properties of wobble-position variants of the unmodified form of Escherichia coli tRNASer1 (the UGA anticodon) were measured in a cell-free translation system. Two variants, with the AGA and CGA anticodons, each exclusively read a single codon, UCU and UCG, respectively. The only case of efficient wo...

journal_title：Biochemical and biophysical research communications

authors： Takai K,Takaku H,Yokoyama S

更新日期：1999-04-21 00:00:00

abstract：:Calmodulin activation of target enzymes depends on the interaction between calmodulin hydrophobic regions and some enzyme areas. The Ca2+ induced exposure of calmodulin hydrophobic sites was studied by means of 2-p-toluidinylnaphthalene-6-sulfonate, a fluorescent probe. Scatchard and Job plots showed that the calmodul...

journal_title：Biochemical and biophysical research communications

authors： Follenius A,Gerard D

更新日期：1984-03-30 00:00:00

abstract：:Protein phosphatase 2C (PP2C) is one of the four major protein serine/threonine phosphatases of eukaryotes and is implicated in the regulation of various cellular functions. With the goal of elucidating the mechanism responsible for regulating PP2C functions, we investigated the significance of phosphorylation of fiss...

journal_title：Biochemical and biophysical research communications

authors： Kobayashi T,Sadaie M,Ohnishi M,Wang H,Ikeda S,Hanada M,Yanagawa Y,Nakajima T,Tamura S

更新日期：1998-10-09 00:00:00

abstract：:p53 mutations are mostly single amino acid changes resulting in expression of a stable mutant protein with "gain of function" (GOF) activity having a dominant oncogenic role rather than simple loss of function of wild-type p53. Knock-down of mutant p53 in human lung cancer cell lines with different endogenous p53 muta...

journal_title：Biochemical and biophysical research communications

authors： Vaughan CA,Frum R,Pearsall I,Singh S,Windle B,Yeudall A,Deb SP,Deb S

更新日期：2012-11-09 00:00:00

abstract：:More than 85% of c-myc transcription is controlled by the nuclease hypersensitive element III(1) upstream of the P1 promoter of this oncogene. The purine-rich sequence in the anti-sense strand forms a G-quadruplex, which has been recently implicated in colorectal cancer, and is proposed as a silencer element [Proc. Na...

journal_title：Biochemical and biophysical research communications

authors： Mathur V,Verma A,Maiti S,Chowdhury S

更新日期：2004-08-06 00:00:00

abstract：:Elevated levels of oxidatively induced DNA lesions have been reported in malignant pancreatic tissues relative to normal pancreatic tissues. However, the ability of the pancreatic cancer cells to remove these lesions has not previously been addressed. This study analyzed the effectiveness of the pancreatic cancer cell...

journal_title：Biochemical and biophysical research communications

authors： Nyaga SG,Lohani A,Evans MK

更新日期：2008-11-14 00:00:00

abstract：:Sphingolipids have been reported to regulate the growth and death of mammalian and yeast cells, but their precise mechanisms are unknown. In this paper, it was shown that the deletion of the oxysterol binding protein homologue 3 (OSH3) gene confers hyper resistance against ISP-1, an inhibitor of sphingolipid biosynthe...

journal_title：Biochemical and biophysical research communications

authors： Yano T,Inukai M,Isono F

更新日期：2004-02-27 00:00:00

abstract：:Vascular remodeling characterized by hyperproliferative neointima formation is an unfavorable repair process that is triggered by vascular damage. This process is characterized by an increased local inflammatory and proliferative response that critically involves the pro-inflammatory cytokine interleukin-1β (IL-1β). I...

journal_title：Biochemical and biophysical research communications

authors： Schlaweck S,Zimmer S,Struck R,Bartok E,Werner N,Bauernfeind F,Latz E,Nickenig G,Hornung V,Ghanem A

更新日期：2011-08-05 00:00:00

abstract：:This study characterized the magnetic materials found within Daphnia resting eggs by measuring static magnetization with a superconducting quantum interference device (SQUID) magnetometer, after forming two types of conditions, each of which consists of zero-field cooling (ZFC) and field cooling (FC). Magnetic ions, s...

journal_title：Biochemical and biophysical research communications

authors： Sakata M,Kawasaki T,Shibue T,Takada A,Yoshimura H,Namiki H

更新日期：2006-12-15 00:00:00

abstract：:The aim of this work was to characterize folates modified by ONOO(-) and HOCl and to evaluate the binding capacity of folates modified by ONOO(-) to folate receptor alpha and beta. For the modification of folate by ONOO(-), folic acid was reacted with the combination of PMA activated PMN and PAPA NONOate or chemically...

journal_title：Biochemical and biophysical research communications

authors： Nakamura M,Nagayoshi R,Ijiri K,Nakashima-Matsushita N,Takeuchi T,Matsuyama T

更新日期：2002-10-11 00:00:00

abstract：:In this study, we used, for the first time, atomic force microscope (AFM) images to investigate the mode of action of DNA topoisomerase I (topo I) in the presence and absence of its inhibitors: camptothecin (CPT) and tyrphostin AG-1387. The results revealed that in the absence of the inhibitors, the enzyme relaxed sup...

journal_title：Biochemical and biophysical research communications

authors： Argaman M,Bendetz-Nezer S,Matlis S,Segal S,Priel E

更新日期：2003-02-14 00:00:00

abstract：:The important role of pyruvate kinase during malarial infection has prompted the cloning of a cDNA encoding Plasmodium falciparum pyruvate kinase (pfPyrK), using mRNA from intraerythrocytic-stage malaria parasites. The full-length cDNA encodes a protein with a computed molecular weight of 55.6 kDa and an isoelectric p...

journal_title：Biochemical and biophysical research communications

authors： Chan M,Sim TS

更新日期：2005-01-07 00:00:00

abstract：:A DNA endonuclease complex which recognizes predominantly pyrimidine dimers in UVC irradiated DNA has been isolated from the chromatin of normal human and xeroderma pigmentosum, complementation group D (XPD) lymphoblastoid cells. The activity of the normal complex on UVC irradiated DNA was increased approximately 2.5 ...

journal_title：Biochemical and biophysical research communications

authors： Parrish DD,Feng X,Lambert MW

更新日期：1992-12-15 00:00:00

abstract：:Metallodaunomycin has been shown to cleave DNA only in the presence of oxygen, a reducing agent and a metal ion under reaction conditions similar to those used for the cuprous-phenanthroline complex. The intermediacy of 02-. and H2O2 has been substantiated by experiments with superoxide dismutase and catalase, respect...

journal_title：Biochemical and biophysical research communications

authors： Mariam YH,Glover GP

更新日期：1986-04-14 00:00:00

abstract：:Nrf2 is a key regulator of many detoxifying enzyme genes, and cytoplasmic protein Keap1 represses the Nrf2 activity under quiescent conditions. Germ line deletion of the keap1 gene results in constitutive activation of Nrf2, but the pups unexpectedly died before weaning. To investigate how constitutive activation of N...

journal_title：Biochemical and biophysical research communications

authors： Okawa H,Motohashi H,Kobayashi A,Aburatani H,Kensler TW,Yamamoto M

更新日期：2006-01-06 00:00:00

abstract：:The polycationic nature of biogenic polyamines such as spermine (SPM, 1) and spermidine (SPD, 2) plays an important role in selective binding to polyanionic nucleic acids. These interactions are mediated by electrostatic and hydrogen bonding forces which led to stabilization of DNA duplexes and triplexes. Transformati...

journal_title：Biochemical and biophysical research communications

authors： Pallan PS,Ganesh KN

更新日期：1996-05-15 00:00:00

abstract：:The Triton X-100 extract of the particulate fraction of porcine spleen contains a protein kinase which can be activated by phospholipid and the phorbol ester TPA but does not respond to phospholipid and calcium. The partially purified kinase has a molecular weight of 76 kDa (p76-kinase) and hence is somewhat smaller t...

journal_title：Biochemical and biophysical research communications

authors： Gschwendt M,Leibersperger H,Marks F

更新日期：1989-11-15 00:00:00

abstract：:The marked impairment of hepatic drug metabolism during inflammation and infections has been known for many years and shown to result from down-regulation of cytochrome P450s (CYP) by cytokines. However, the mechanism of this repression is unknown. Using primary cultures of human hepatocytes, we show here that interle...

journal_title：Biochemical and biophysical research communications

authors： Pascussi JM,Gerbal-Chaloin S,Pichard-Garcia L,Daujat M,Fabre JM,Maurel P,Vilarem MJ

更新日期：2000-08-11 00:00:00

abstract：:GPR109A (PUMA-G, NIACR1, HCA(2)) and GPR81 (HCA(1)) are G protein-coupled receptors located predominantly on adipocytes that mediate anti-lipolytic effects. These cell surface receptors give the adipocyte the ability to "sense" metabolic changes in the environment and respond through lipolytic regulation and release o...

journal_title：Biochemical and biophysical research communications

authors： Wanders D,Graff EC,Judd RL

更新日期：2012-08-24 00:00:00

abstract：:Zymosan particles opsonised with human serum factors functionally activate human neutrophils and induce a substantial modification of the human neutrophil cytosolic glyoxalase system. The activity of glyoxalase I increases and the activity of glyoxalase II decreases by 20-40% of their resting cell activities during th...

journal_title：Biochemical and biophysical research communications

authors： Thornalley PJ,Della Bianca V,Bellavite P,Rossi F

更新日期：1987-06-15 00:00:00

abstract：:We have developed a solid matrix immunoassay to determine the binding of interleukin-2 (IL-2) to specific gangliosides. The assay establishes that recombinant human IL-2 binds to ganglioside GD(1b) but not to any other gangliosides (GM(1), GM(2), GM(3), GD(1a), GD(2), GD(3), and GT(1b)). The binding varies with the ra...

journal_title：Biochemical and biophysical research communications

authors： Ravindranath MH,Gonzales A,Soh D,Nishimoto K,Tam WY,Bilchik A,Morton DL,O'Day S

更新日期：2001-05-04 00:00:00

abstract：:After screening the data base of the Berkeley Drosophila Genome Project with a sequence coding for the transmembrane region of a G protein-coupled receptor, we found that Drosophila might contain a gene coding for a receptor that is structurally related to the Gonadotropin-Releasing Hormone (GnRH) receptors from verte...

journal_title：Biochemical and biophysical research communications

authors： Hauser F,Søndergaard L,Grimmelikhuijzen CJ

更新日期：1998-08-28 00:00:00

abstract：:The purpose of the present study was to investigate the effect of acute exercise on lipolysis via coordination of hormone-sensitive lipase (HSL) and scaffold proteins, i.e., perilipin A and comparative gene identification-58 (CGI-58), in rat primary adipocytes. Glycerol release was significantly elevated immediately (...

journal_title：Biochemical and biophysical research communications

authors： Ogasawara J,Nomura S,Rahman N,Sakurai T,Kizaki T,Izawa T,Ishida H,Haga S,Ohno H

更新日期：2010-09-10 00:00:00

abstract：:Cisplatin is one of the most widely used anticancer agents. Cisplatin-induced cytotoxicity results from its ability to form cisplatin-DNA adducts within the cellular genome which can inhibit the transcription of genes and the replication of DNA. Cisplatin-adducts are primarily removed by the nucleotide excision repair...

journal_title：Biochemical and biophysical research communications

authors： Yang WL,Cvijic ME,Ishii K,Chin KV

更新日期：1998-09-29 00:00:00

abstract：:Streptococcus pneumoniae is a major pathogen of community-acquired pneumonia and one of its major virulence factors is pneumolysin, which functions as a cholesterol-dependent cytolytic pore-forming toxin. In this study, we identified the ply-like gene spd0729 in a BLAST search. Unexpectedly, hemolytic and cytotoxic as...

journal_title：Biochemical and biophysical research communications

authors： Yamaguchi M,Minamide Y,Terao Y,Isoda R,Ogawa T,Yokota S,Hamada S,Kawabata S

更新日期：2009-12-04 00:00:00