Essential thrombocythemia with acquired von Willebrand's disease.

abstract：:Quantitative morphometry was used to evaluate the homogeneity of lymphoid cell populations in fine-needle aspiration cytology smears of lymph nodes from eight non-Hodgkin's lymphomas and four benign lymphoid proliferations. Using the standard deviation of log-transformed nuclear areas as the measure of lymphoid cell h...

journal_title：American journal of clinical pathology

authors： Dawsey SM,Korn EL,Layfield LJ

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVES:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. Genetic abnormalities associated with AML-MRC are often associated with adverse prognostic features, and many cases are preceded by a myelodysplastic syndrom...

journal_title：American journal of clinical pathology

authors： Vardiman J,Reichard K

更新日期：2015-07-01 00:00:00

abstract：:The reliability of "standard" plasmas used by clinical laboratories to assay factor VIII concentrations of patients' plasmas was studied by assessing the credibility of their reference values. Two of three commercial reference plasmas were considered to be unreliable. The third commercial reference plasma appeared to ...

journal_title：American journal of clinical pathology

authors： Harper TA,Bailey EL,Chauhan K

更新日期：1981-02-01 00:00:00

abstract：:A 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine A, azathioprine, and prednisolone). During her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated a...

journal_title：American journal of clinical pathology

authors： Kemnitz J,Cremer J,Gebel M,Uysal A,Haverich A,Georgii A

更新日期：1990-07-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is one of the most potent mitogenic, highly specific tumor angiogenic factors, which acts via binding to 2 specific tyrosine kinase receptors. There are few studies analyzing VEGF receptor expression in prostate cancer cells, and results are contradictory. In an immunohistoche...

journal_title：American journal of clinical pathology

authors： Köllermann J,Helpap B

更新日期：2001-07-01 00:00:00

abstract：:Diffuse alveolar damage (DAD) is usually considered a generalized lung process. During five years the authors observed 83 patients with generalized DAD in 827 adult autopsies (10.1%) and 10 patients with identical, but localized, lesions. The authors propose the term regional alveolar damage (RAD) to designate localiz...

journal_title：American journal of clinical pathology

authors： Yazdy AM,Tomashefski JF Jr,Yagan R,Kleinerman J

更新日期：1989-07-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:An unusual case of acute myelomonocytic leukemia (AMML) in an 81-year-old man is described. Ultrastructural examination revealed the presence of distinct Auer bodies, which commonly are found in acute promyelocytic leukemia (APL). The Auer bodies had a splinterlike appearance with a distinct tubular substructure. The ...

journal_title：American journal of clinical pathology

authors： Payne CM,Harrow EJ

更新日期：1983-08-01 00:00:00

abstract：:The probabilities of low transferrin saturation, folic acid, or vitamin B12 levels in association with various erythrocyte indices was determined from the prevalences of these abnormalities and the distributions of the indices among 206 hospitalized and 1,000 ambulatory anemic patients. At mean corpuscular hemoglobin ...

journal_title：American journal of clinical pathology

authors： Griner PF,Oranburg PR

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVES:Cytogenetics defines disease entities and predicts prognosis in acute myeloid leukemia (AML). Conventional karyotyping provides a comprehensive view of the genome, while fluorescence in situ hybridization (FISH) detects targeted abnormalities. The aim of this study was to compare the utility of karyotyping a...

journal_title：American journal of clinical pathology

authors： He R,Wiktor AE,Hanson CA,Ketterling RP,Kurtin PJ,Van Dyke DL,Litzow MR,Howard MT,Reichard KK

更新日期：2015-06-01 00:00:00

abstract：:Tumors and pseudotumors of the liver account for fewer than 2% of the tumors in children and vary considerably in incidence throughout the pediatric age range, with hepatoblastoma, infantile hemangioendothelioma, and mesenchymal hamartoma seen most frequently in the first 2 years of life and hepatocellular carcinoma, ...

journal_title：American journal of clinical pathology

authors： Stocker JT

更新日期：1998-04-01 00:00:00

abstract：:To assess the observation that blood type B might be a marker for longevity, we reviewed the records and determined the ABO blood types of all patients who died in our hospital in 2004. Age was stratified by decade of death, and linear regressions were calculated by ABO percentage. ABO survival curves were compared. I...

journal_title：American journal of clinical pathology

authors： Brecher ME,Hay SN

更新日期：2011-01-01 00:00:00

abstract：:A tumor of the larynx composed of a small infiltrating and well-differentiated squamous cell carcinoma and a large polypoid sarcomatous mass showing the histologic features of the malignant giant cell tumor of soft parts (MGCT) is reported. Other types of sarcomatous components have been described with squamous cell c...

journal_title：American journal of clinical pathology

authors： Alguacil-Garcia A,Alonso A,Pettigrew NM

更新日期：1984-09-01 00:00:00

abstract：:Three cases of pulmonary squamous cell carcinoma (SCC) are described displaying a prominent microcystic pattern closely resembling microcystic adnexal carcinoma of the skin (MAC). The patients were 2 women and 1 man aged 72 to 83 years. Histologically, in addition to conventional SCC, all tumors showed striking microc...

journal_title：American journal of clinical pathology

authors： Weissferdt A,Moran CA

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To assess the ability of flow cytometry (FC) to detect putative neoplastic T-cell subsets on skin shave biopsy (SSB) specimens from patients with mycosis fungoides (MF) and to study the immunophenotype of skin-infiltrating tumor cells in MF. METHODS:SSB specimens from patients with suspected MF were bisecte...

journal_title：American journal of clinical pathology

authors： Horna P,Kurant D,Sokol L,Sotomayor EM,Moscinski L,Glass LF

更新日期：2015-06-01 00:00:00

abstract：:This report describes the use of counterimmunoelectrophoresis (CIE) as a method of detecting activation of the complement system. With this technic small amounts of C3 split products (C3c/d) can be detected in plasma samples by specific precipitation with antiserum in less than two hours. The CIE technic is a highly s...

journal_title：American journal of clinical pathology

authors： Arroyave CM,Taylor DG,Gallup P,Nakamura RM

更新日期：1978-04-01 00:00:00

abstract：OBJECTIVES:To demonstrate the impact of genetics specialists on identifying test order errors and improving reimbursement for genetic testing. METHODS:Forty-four cases in which whole exome sequencing (WES) was performed but not reimbursed were reviewed by a genetic counselor through simulated prospective and retrospec...

journal_title：American journal of clinical pathology

authors： Conway ME,Kalejta CD,Sternen DL,Singh IR

更新日期：2020-03-09 00:00:00

abstract：:The thickness of eosinophilic band in collagenous colitis (CC) was assessed by 3 methods: histologic estimates (22 observers), conventional measurements using a calibrated micrometric scale (1 observer), and semiautomatic micrometric measurements (1 observer). By the histologic estimate technique, 7.4% of the results ...

journal_title：American journal of clinical pathology

authors： Rubio CA,Orrego A,Höög A,Porwitz A,Petersson F,Elmberger G,Glaessgen A,Eriksson E,Kanter L,Jaremko G,Egevad L,Laforga J,Liljefors M,Löfdahl B,Norman P,Larsson O,Wanat R,Wejde J,Zickert P,Björk J,Caini S,Palli D

更新日期：2008-09-01 00:00:00

abstract：:Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas. The tumors in six cases (Group I) were identical to one or another form of well-recognized end...

journal_title：American journal of clinical pathology

authors： Clement PB,Scully RE

更新日期：1976-09-01 00:00:00

abstract：:While plasmacytosis is a common occurrence in early post-bone marrow transplantation biopsy specimens, the significance of plasma cells in such specimens from patients with multiple myeloma (MM) is unknown. We attempted to retrospectively determine, by morphologic assessment of plasma cell percentage, immunohistologic...

journal_title：American journal of clinical pathology

authors： Maia DM,Kell DL,Goates JJ,Warnke RA

更新日期：1997-06-01 00:00:00

abstract：:The demonstration of carcinoembryonic antigen (CEA) in serum and in tissue sections may be of value in diagnosis and follow-up of several malignant tumors. Anti-CEA sera, however, cross-react with normal antigens, also present in tumors. The staining patterns of three commercially produced anti-CEA sera were investiga...

journal_title：American journal of clinical pathology

authors： Nap M,ten Hoor KA,Fleuren GJ

更新日期：1983-01-01 00:00:00

abstract：:Two separate courses in clinical pathology were presented to two groups of second-year medical students. The first (large) group was taught by the conventional lecture method; the other (small) group, by a self-instructional method for roughly half of the course, followed by the conventional lecture method for the sec...

journal_title：American journal of clinical pathology

authors： Kao YS,Beeler MF,Strong JP

更新日期：1978-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine if the Advia 2120 hematology analyzer (Siemens Healthcare Diagnostics, Deerfield, IL) can accurately quantify both WBCs and the proportion of neutrophils from synovial and ascitic body fluids. METHODS:We analyzed 60 samples on the Advia and compared the results wit...

journal_title：American journal of clinical pathology

authors： Froom P,Diab A,Barak M

更新日期：2013-12-01 00:00:00

abstract：:The authors describe the case of a 33-year-old man with a solitary cystic lesion of the left distal radius with central radiodensities that radiographically suggested a chondroid matrix. Curettage of the lesion revealed numerous calcospherites with a lamellar structure. This lamellar pattern is thought to be a result ...

journal_title：American journal of clinical pathology

authors： Kragel PJ,Williams J,Garvin DF,Goral AB

更新日期：1989-12-01 00:00:00

abstract：:Patients with nonhemolytic Lewis antibodies in the serum were transfused on the basis of major crossmatch compatibility alone. No adverse clinical affects were noted when 33 such patients received a total of 230 transfusions. Considerable savings in technologist time and reagent cost were realized by adopting this pol...

journal_title：American journal of clinical pathology

authors： Waheed A,Kennedy MS,Gerhan S,Senhauser DA

更新日期：1981-09-01 00:00:00

abstract：:It has been suggested that kallikrein inhibition may predispose patients with the lupus inhibitor to thrombosis by interfering with the Factor XII-mediated activation of plasminogen. To further investigate this suggestion, the authors measured kallikrein inhibition in 19 patients with the lupus inhibitor. They found t...

journal_title：American journal of clinical pathology

authors： Killeen AA,Meyer KC,Vogt JM,Edson JR

更新日期：1987-08-01 00:00:00

abstract：:It has been shown that the monoclonal antibody Ki-67 reacts with a nuclear antigen that is expressed only by proliferating cells. The feasibility of using image analysis to quantitate Ki-67 staining (proliferation index [PI]) of epithelial ovarian cancers was investigated. The PI was determined in 50 advanced-stage pr...

journal_title：American journal of clinical pathology

authors： Jordan PA,Kerns BJ,Pence JC,Kohler MF,Bast RC Jr,Kinney RB,Berchuck A

更新日期：1993-06-01 00:00:00

abstract：:Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody ar...

journal_title：American journal of clinical pathology

authors： Hollinger FB,Bradley DW,Dreesman GR,Melnick JL

更新日期：1976-05-01 00:00:00

abstract：:The radioimmunoassay of ACTH was used in a routine laboratory to localize the site of the lesion in 20 patients with Cushing's syndrome. Eight of the patients had no detectable circulating ACTH and had adrenal tumors removed, 12 had high levels and were diagnosed as having pituitary Cushing's syndrome. Very high level...

journal_title：American journal of clinical pathology

authors： Broughton A

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...

journal_title：American journal of clinical pathology

authors： Benirschke RC,Gniadek TJ

更新日期：2020-07-07 00:00:00