Macrophages in the central nervous system of the rat.

abstract：BACKGROUND:T helper cells can differentiate into several subsets of T lymphocytes, including Th1, Th2, and regulatory T (Treg) cells. As a result of this ability to differentiate, the corresponding T cell receptor (TCR) spectra display considerable cellular plasticity and interchangeability. In contrast, T lymphocyte d...

journal_title：Immunobiology

authors： Arneth B

更新日期：2017-07-01 00:00:00

abstract：:Cytotoxicity and production of cytokines are two important functions of NK cells. These two different NK functions were studied in a syngeneic rat model in relation to MHC class I expression. We focussed on the mechanism by which NK cells modulate MHC class I expression on target cells and how this interferes with NK ...

journal_title：Immunobiology

authors： Jonges LE,Giezeman-Smits KM,van Vlierberghe RL,Ensink NG,Hagenaars M,Joly E,Eggermont AM,van de Velde CJ,Fleuren GJ,Kuppen PJ

更新日期：2000-11-01 00:00:00

abstract：:Previous studies have demonstrated that methamphetamine (METH) alter inflammatory and anti-inflammatory cytokine production in the periphery. However, the effect of METH on lipopolysaccharide (LPS)-induced immune responses and its underlying mechanism of action remains unclear. The dopamine D3 receptor (D3R) plays an ...

journal_title：Immunobiology

authors： Xue L,Li X,Ren HX,Wu F,Li M,Wang B,Chen FY,Cheng WY,Li JP,Chen YJ,Chen T

更新日期：2015-06-01 00:00:00

abstract：:We examined the expression of seven V alpha or V beta T cell receptor (TCR) segments on human CD4+ and CD8+ T cells. Confirming previously published results, we found a preferential expression of four V segment gene products on CD4+ T cells. One of these markers (V beta 6.7) was constantly expressed on more CD4+ T cel...

journal_title：Immunobiology

authors： Dannecker G,Mecheri S,Heuser M,Ihle J,Hoffmann MK,Niethammer D

更新日期：1993-01-01 00:00:00

abstract：:To date, numerable reviews are found in the literature prominent to the effect of caffeine on the immune system, with the latest review published in 2006. Database screening reveals around three thousand articles that have been published during the last decade. Interestingly, less than hundred articles involved humans...

journal_title：Immunobiology

authors： Al Reef T,Ghanem E

更新日期：2018-12-01 00:00:00

abstract：:Recent studies have suggested that odontoblasts are involved in the dental pulp immune response to oral pathogens that invade human dentin during the caries process. How odontoblasts regulate the early inflammatory and immune pulp response to Gram-positive bacteria, which predominate in shallow and moderate dentin car...

journal_title：Immunobiology

authors： Farges JC,Carrouel F,Keller JF,Baudouin C,Msika P,Bleicher F,Staquet MJ

更新日期：2011-04-01 00:00:00

abstract：:Infection of human monocytes with influenza A virus induces a broad range of proinflammatory cytokines and mononuclear cell attracting chemokines before the infected cells undergo apoptosis. The underlying mechanisms by which the corresponding genes are transcriptionally initiated after virus infection are still poorl...

journal_title：Immunobiology

authors： Bussfeld D,Bacher M,Moritz A,Gemsa D,Sprenger H

更新日期：1997-12-01 00:00:00

abstract：:Immunization using human papilloma virus (HPV)-L1 virus-like particles (VLPs) induces a robust and effective immune response, which has recently resulted in the implementation of the HPV-L1 VLP vaccination in health programs. However, during infection, HPV can escape immune surveillance leading to latency and disease....

journal_title：Immunobiology

authors： de Witte L,Zoughlami Y,Aengeneyndt B,David G,van Kooyk Y,Gissmann L,Geijtenbeek TB

更新日期：2007-01-01 00:00:00

abstract：:Considering that imbalance of central tolerance in the thymus contributes to aggressive autoimmunity, we compared the expression of peripheral tissue autoantigens (PTA) genes, which are involved in self-representation in the thymic stroma, of two mouse strains; DBA-1/J (MHC-H2(q)) susceptible and DBA-2/J (MHC-H2(d)) r...

journal_title：Immunobiology

authors： Donate PB,Fornari TA,Junta CM,Magalhães DA,Macedo C,Cunha TM,Nguyen C,Cunha FQ,Passos GA

更新日期：2011-05-01 00:00:00

abstract：:Interleukin-7 (IL-7) supports the proliferation of mature T lymphocytes, however, the cellular source of IL-7 for T lymphocyte activation has not been well established. We therefore investigated whether human peripheral blood dendritic cells (DC) produce IL-7 as a contribution towards T lymphocyte activation. Human CM...

journal_title：Immunobiology

authors： Sorg RV,McLellan AD,Hock BD,Fearnley DB,Hart DN

更新日期：1998-03-01 00:00:00

abstract：:Attenuating the sepsis-induced systemic inflammatory response, with subsequent homeostatic imbalance, has for years been one of the main tasks in sepsis related research. Complement and the TLR family constitute two important upstream sensor and effector-systems of innate immunity. Although they act as partly independ...

journal_title：Immunobiology

authors： Barratt-Due A,Pischke SE,Brekke OL,Thorgersen EB,Nielsen EW,Espevik T,Huber-Lang M,Mollnes TE

更新日期：2012-11-01 00:00:00

abstract：:OK-432, a streptococcal preparation, has been shown as an effective activator to induce human monocyte-derived dendritic cells maturation. During this process, the activation of Toll-like receptor 4 plays an important role. However, the signaling pathway involved in has not been fully understood. In the present study,...

journal_title：Immunobiology

authors： Pan K,Wang H,Liu WL,Zhang HK,Zhou J,Li JJ,Weng DS,Huang W,Sun JC,Liang XT,Xia JC

更新日期：2009-01-01 00:00:00

abstract：:The majority of B lymphocytes, virgin T lymphocytes and a subpopulation of memory T cells express the addressin, L-selectin. Natural killer (NK) cells in rodents and humans also express L-selectin. We have shown that a similar proportion (40%) of NK cells in mouse spleen also express the integrin, CD18Mac-1, and moreo...

journal_title：Immunobiology

authors： Lejtenyi D,Osmond DG,Miller SC

更新日期：2003-01-01 00:00:00

abstract：:CD4(+)CD25(+)Foxp3(+) T regulatory cells (Tregs) and CD1d-restricted invariant natural killer T (iNKT) cells are two cell types that are known to regulate immune reactions. Depletion or inactivation of Tregs using specific anti-CD25 antibodies in combination with immunostimulation is an attractive modality especially ...

journal_title：Immunobiology

authors： Rosalia RA,Štěpánek I,Polláková V,Šímová J,Bieblová J,Indrová M,Moravcová S,Přibylová H,Bontkes HJ,Bubeník J,Sparwasser T,Reiniš M

更新日期：2013-06-01 00:00:00

abstract：:High Mphi:T cell ratios suppress the immune response to the retroviral superantigen Mls by IFNgamma-triggered production of the arg- and trp-consuming enzymes iNOS and IDO. Attempts to reverse suppression by treatment with pro-inflammatory cytokines revealed that IL-6 improved the T cell response to Mls and the pro-he...

journal_title：Immunobiology

authors： Silberman D,Bucknum A,Kozlowski M,Matlack R,Riggs J

更新日期：2010-01-01 00:00:00

abstract：:Activity of acid phosphatase was found to be higher in T than in non-T cells of human peripheral blood lymphocytes. The T cell mitogen PHA induced an increase in the magnitude of acid phosphatase activity, while the B cell mitogen LPS was not able to produce any effect on acid phosphatase activity. Acid phosphatase ac...

journal_title：Immunobiology

authors： Myśliwska J,Myśliwski A,Grzegorzewski K,Witkowski J

更新日期：1985-03-01 00:00:00

abstract：:C1r, the enzyme responsible for intrinsic activation of the C1 complex of complement, is a modular serine protease featuring an overall structural organization homologous to those of C1s and the mannan-binding lectin-associated serine proteases (MASPs). This review will initially summarize current information on the s...

journal_title：Immunobiology

authors： Arlaud GJ,Gaboriaud C,Garnier G,Circolo A,Thielens NM,Budayova-Spano M,Fontecilla-Camps JC,Volanakis JE

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:An association between Tako-Tsubo cardiomyopathy (TTC) and underlying malignancies has been observed, suggesting that TTC might be the consequence of paraneoplastic phenomena. This study investigates the presence of autoantibodies against cardiomyocytes as well as adrenergic (β1, β2) and muscarinic (M2) rece...

journal_title：Immunobiology

authors： Juenemann M,Nef H,Möllmann H,Singh P,Troidl C,Schramm P,Kaps M,Gerriets T,Blaes F,Tschernatsch M

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:The interaction between the immune system and malignant diseases is a proven key target for cancer therapy. We describe an innovative 3D cell culture system comprising both immune and cancer cells to evaluate their interaction and immune cell infiltration to provide an innovative in vitro screening of immu...

journal_title：Immunobiology

authors： Koeck S,Zwierzina M,Huber JM,Bitsche M,Lorenz E,Gamerith G,Dudas J,Kelm JM,Zwierzina H,Amann A

更新日期：2016-05-01 00:00:00

abstract：:Chitin and β-glucan are conserved throughout evolution in the fungal cell wall and are the most common polysaccharides in fungal species. Together, these two polysaccharides form a structural scaffold that is essential for the survival of the fungus. In the present study, we demonstrated that Aspergillus fumigatus alk...

journal_title：Immunobiology

authors： Dubey LK,Moeller JB,Schlosser A,Sorensen GL,Holmskov U

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The soluble form of the haptoglobin-hemoglobin (Hp-Hb) scavenger receptor (sCD163) is a specific plasma/serum marker for macrophage activity. Here, we have characterized molecular forms in serum and investigated a role of sCD163 as a binder of Hp-Hb complexes. METHODS:The sCD163 species in serum (from 50 he...

journal_title：Immunobiology

authors： Møller HJ,Nielsen MJ,Maniecki MB,Madsen M,Moestrup SK

更新日期：2010-05-01 00:00:00

abstract：:According to present concepts, innate immunity plays an important role in tumor surveillance and immune modulation. The state of NK cells depends on the balance between inhibitory and activating signals from corresponding receptors. As one of the activating receptors, NKG2D recognises some self ligands such as MICA/B ...

journal_title：Immunobiology

authors： Cao W,He W

更新日期：2004-01-01 00:00:00

abstract：:Dendritic cells capture and process antigen and present it to T lymphocytes in the lymphoid organs. Dendritic cells of the skin, including epidermal Langerhans cells, langerin(+) and langerin(negative) dermal dendritic cells are ideally positioned to take up pathogens that enter the body through the skin or vaccines t...

journal_title：Immunobiology

authors： Sparber F,Tripp CH,Hermann M,Romani N,Stoitzner P

更新日期：2010-09-01 00:00:00

abstract：:The course of legionella pneumonia in guinea pigs after infection with various quantities of virulent L. pneumophila serogroup 1 organisms by aerosol exposure was investigated. The clinical course, histopathological characteristics, manifestations in the lungs and clearance of the legionella organisms from the lungs a...

journal_title：Immunobiology

authors： Twisk-Meijssen MJ,Meenhorst PL,van Cronenburg BJ,Mulder JD,Scheffer E,van Furth R

更新日期：1987-12-01 00:00:00

abstract：:Dogs with lymphoma are established as good model for human non-Hodgkin lymphoma studies. Canine cell lines derived from lymphomas may be valuable tools for testing new therapeutic drugs. In this context, we established a canine T-cell line, PER-VAS, from a primary aggressive T-cell lymphoma with large granular morphol...

journal_title：Immunobiology

authors： Bonnefont-Rebeix C,Fournel-Fleury C,Ponce F,Belluco S,Watrelot D,Bouteille SE,Rapiteau S,Razanajaona-Doll D,Pin JJ,Leroux C,Marchal T

更新日期：2016-01-01 00:00:00

abstract：:Shigella spp. are known to penetrate the colonic epithelial cells causing shigellosis, which results in production of convalescent antibodies against porin, the surface exposed major outer membrane protein. Porin has been categorized as primarily TLR2-ligand and here we validated its signaling procedure in colonic INT...

journal_title：Immunobiology

authors： Mukherjee S,Sinha D,Ghosh AK,Biswas T

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:NK cells as a part of innate immune system, are controlled by a set of activating and inhibitory KIR receptors (aKIR, iKIR) which are implicated in tumor microenvironment immunity through a variety of activating and inhibitory immune signals. KIRs are multi gene family receptors that differ in the number and...

journal_title：Immunobiology

authors： Barani S,Taghipour M,Ghaderi A

更新日期：2020-03-01 00:00:00

abstract：:This is the first application of flow cytometry for the detection of lamina propria plasma cells and their intracellular immunoglobulins in patients with inflammatory bowel disease compared to healthy controls. The study has been focused on the distribution of IgA, IgG, IgM and the four IgG subclasses. Plasma cells we...

journal_title：Immunobiology

authors： Dorn I,Schlenke P,Mascher B,Stange EF,Seyfarth M

更新日期：2002-12-01 00:00:00

abstract：:Tumor necrosis factor superfamily (TNFSF) represents a group of multifunctional inflammatory cytokines that have been shown to participate in a variety of pathological and immunological process. However, the functions of these proteins in oyster are still poorly understood. In the present study, an oyster TNF homolog ...

journal_title：Immunobiology

authors： Qu F,Xiang Z,Zhang Y,Li J,Xiao S,Zhang Y,Qin Y,Zhou Y,Yu Z

更新日期：2017-05-01 00:00:00

abstract：:The process of thymopoiesis is tightly regulated by a series of selection events which ensure that only functional T-lymphocytes directed against foreign antigens are exported into the periphery. The adaptive immune response largely depends on the regulation of thymocyte development, and thymocytes which fail selectio...

journal_title：Immunobiology

authors： Hutcheson J,Perlman H

更新日期：2007-01-01 00:00:00