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Effect of circulatory assistance on premature death and long-term prognosis.

Abstract：

BACKGROUND:Patients undergoing urgent heart transplantation (HT) have a poorer prognosis and more long-term complications. The objective of this study was to compare the preoperative course in patients undergoing urgent HT according to the need for preoperative intra-aortic balloon counterpulsation (IABP). MATERIALS AND METHODS:We studied 102 consecutive patients including 23 patients with IABP who underwent urgent HT between January 2000 and September 2006. We excluded patients who received combination transplants, those who underwent repeat HT, and pediatric patients who underwent HT. The statistical methods used were the t test for quantitative variables and the chi(2) test for qualitative variables. A logistic regression model was constructed to assess the possible relationship between IABP and other variables on premature death within 30 days after HT. RESULTS:Mean (SD) patient-age was 50 (10) years. No significant differences were observed in baseline characteristics between the IABP and the non-IAPB groups. The IABP patient group had higher rates of acute graft failure (45.5% vs 35.4%; P = .46) and premature death (18.8% vs 14.8%; P = .67) and shorter long-term survival (40.6 [34.9] vs 54.5 [43.7] mo; P = .30). Multivariate analysis demonstrated no association between the need for IABP and increased frequency of premature death. CONCLUSIONS:Use of IABP is not associated with premature or late death. We recommend use of IABP in patients with acute decompensated heart failure to stabilize them before HT.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Sánchez Lázaro IJ,Almenar Bonet L,Martínez-Dolz L,Moro López J,Rueda Soriano J,Arnau Vives MA,Buendía Fuentes F,Ortiz Martínez V,Cano Pérez O,Sánchez Soriano R,Salvador Sanz A

doi

10.1016/j.transproceed.2008.08.114

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

3025-6

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(08)01192-5

journal_volume

40

pub_type

杂志文章

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