Taurine protects against ischemia-reperfusion injury in rabbit livers.


:Ischemia-reperfusion injury is of major clinical relevance during liver transplantation. In the present study, the therapeutic efficacy of taurine to protect against ischemia-reperfusion injury was investigated in rabbit livers. We demonstrated that intravenous injection of taurine attenuated liver dysfunction as evidenced by reductions in serum alanine aminotransferase, aspartate transaminase, and alkaline phosphatase. The recovery of morphological and ultrastructural changes in the liver was also promoted by taurine. The mechanism of the protective effect of taurine seems at least to rely on antioxidation, since the lipoperoxides contents in liver tissues were significantly reduced among taurine-treated rabbits. These results suggest that taurine is a potent useful reagent to protect the rabbit liver from ischemia-reperfusion injury.


Transplant Proc


Tong L,Li J,Qiao H,Jiang H,Meng F,Sun X




Has Abstract


2006-06-01 00:00:00














  • Blood pressure control according to the prevalence of diabetes in renal transplant recipients.

    abstract::Hypertension is one of the most frequent complications of renal transplantation. About 70% to 90% of this population display either high blood pressure (BP) or require antihypertensive therapy. Diabetes mellitus is also a common finding among kidney transplant recipients. The aim of the study was to assess the BP cont...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Zbroch E,Malyszko J,Glowinska I,Maciorkowska D,Kobus G,Mysliwiec M

    更新日期:2013-01-01 00:00:00

  • Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal.

    abstract::The objectives of the present study were to evaluate the incidence of malignancies and to describe the effects of immunosuppression on survival and recurrence of malignancies after heart transplantation (HTX). Data were analyzed in 211 cardiac allograft recipients, in whom HTX was performed between 1989 and 2005. All ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Doesch AO,Müller S,Konstandin M,Celik S,Kristen A,Frankenstein L,Ehlermann P,Sack FU,Katus HA,Dengler TJ

    更新日期:2010-11-01 00:00:00

  • Expanding the living donor pool, "Ist Act": analysis of the causes of exclusion of potential kidney donors.

    abstract:BACKGROUND:The evaluation of a potential living kidney donor (LKD) leads to exclusion of at least 50% of candidates. The aim of this study was to analyze the reasons for exclusion of potential LKDs referred to our center. METHODS:We retrospectively analyzed historic and clinical data of all potential LKDs who were eva...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Romagnoli J,Salerno MP,Calia R,Bianchi V,Pedroso JA,Spagnoletti G,Citterio F

    更新日期:2013-09-01 00:00:00

  • Isolated cardiac sarcoidosis in heart transplantation.

    abstract:BACKGROUND:Heart transplantation is the ultimate treatment for end-stage heart failure. Cardiac sarcoidosis has rarely been reported in heart transplantation worldwide. Their long-term prognosis after heart transplantation is unknown. Herein we have presented clinical and pathological observations among heart transplan...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Chang TI,Chi NH,Chou NK,Tsao CI,Yu HY,Chen YS,Wang SS

    更新日期:2012-05-01 00:00:00

  • Cerebral blood flow in fulminant hepatitis.

    abstract::Fulminant hepatic failure (FHF) is often complicated with cerebral edema, intracranial hypertension, and coma. Cytotoxic and vasogenic factors have been recognized in the etiology of cerebral edema. One of the main causes seems to be the accumulation of glutamine in astrocytes, which is produced from ammonia and the e...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Feltracco P,Serra E,Barbieri S,Tiberio I,Rizzi S,Salvaterra F

    更新日期:2006-04-01 00:00:00

  • The clinical outcome of end-stage renal disease patients who return to peritoneal dialysis after renal allograft failure.

    abstract:BACKGROUND:With the increased numbers of kidney transplantations, more patients return to dialysis after graft loss (DAGL). The aim of this study was to investigate the safety and efficacy of peritoneal dialysis (PD) after graft loss compared with transplant-naive PD patients (TN-PD). METHOD:This study was conducted o...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yang KS,Kim JI,Moon IS,Choi BS,Park CW,Yang CW,Kim YS,Chung BH

    更新日期:2013-10-01 00:00:00

  • A Noninvasive and Donor-independent Method Simultaneously Monitors Rejection and Infection in Patients With Organ Transplant.

    abstract:BACKGROUND:Rejection and infection are 2 major complications affecting the health and survival of patients receiving an allograft organ transplantation. We describe a diagnostic assay that simultaneously monitors for rejection and infection in recipients of kidney transplant by sequencing of cell-free DNA (cfDNA) in pl...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Zhou Y,Yang G,Liu H,Chen Y,Li X,Ge J,Wang X,Niu H,Dong W,Jiang T,Shi H,Peng L,Liu L

    更新日期:2019-01-01 00:00:00

  • Modified liver-free multivisceral transplantation for a metastatic small bowel neuroendocrine tumor: a case report.

    abstract::Neuroendocrine tumors originating from the small bowel frequently metastasize to the lymph nodes and/or liver. Although surgical extirpation of the primary tumor and locoregional metastases epitomizes the management of patients with such tumors, this is not always possible with conventional surgical techniques. Nonres...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Frilling A,Giele H,Vrakas G,Reddy S,Macedo R,Al-Nahhas A,Wasan H,Clift AK,Gondolesi GE,Vianna RM,Friend P,Vaidya A

    更新日期:2015-04-01 00:00:00

  • Induction of porcine regulatory cells by mycophenolic Acid-treated dendritic cells.

    abstract::Tolerance induction in murine allogeneic transplantation is relatively easy, often by induction of regulatory T cells (Treg). Unfortunately, the implementation of these models in clinical situations has not yielded reliable protocols of tolerance induction in humans. Our project sought to create a preclinical model of...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Pilon C,Meurens F,Dauba A,Salmon H,Velge-Roussel F,Lebranchu Y,Baron C

    更新日期:2009-03-01 00:00:00

  • Minimally invasive methods for the treatment of lymphocele after kidney transplantation.

    abstract:BACKGROUND:One common complication after kidney transplantation is a lymphocele. The aim of our work was an analysis of incidence of lymphocele and the effectiveness of minimal invasive methods in the management of this complication. MATERIALS AND METHODS:The examined group was consisted of 158 patients (68 female and...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Iwan-Zietek I,Zietek Z,Sulikowski T,Nowacki M,Zair L,Romanowski M,Zukowski M,Rość D,Ostrowski M

    更新日期:2009-10-01 00:00:00

  • Therapeutic monitoring of sirolimus: its contribution to optimal prescription.

    abstract::It is now common practice to measure immunosuppressive drugs in blood as a guide to therapy. The immunosuppressive drug sirolimus, recently approved for use following kidney transplantation, was developed in the context of this clinical approach. Throughout the early clinical studies, validated analytical techniques b...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Holt DW,Denny K,Lee TD,Johnston A

    更新日期:2003-05-01 00:00:00

  • Improvement over the years of long-term survival in high-risk lymphoma patients treated with hematopoietic stem cell transplantation as consolidation or salvage therapy.

    abstract::The role of hemopoietic stem cell transplantation (HSCT) is not well established in certain types of lymphoma, such as those with a high relapse risk or relapsing after initial therapy. New chemotherapeutic schemes and immunotherapy have improved survival of these patients. Nevertheless, there is not enough evidence r...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Calderón-Cabrera C,Márquez-Malaver FJ,de la Cruz-Vicente F,Falantes F,Carrillo E,Parody R,Montero I,González Campos J,Martino ML,Carmona M,Pérez-Simón JA,Espigado I

    更新日期:2013-01-01 00:00:00

  • Carbapenem-resistant Acinetobacter baumannii Bacteremia in Liver Transplant Recipients.

    abstract:BACKGROUND:Acinetobacter baumannii has become an increasingly important nosocomial pathogen. Carbapenem is the preferred drug of choice for treatment of multidrug-resistant gram-negative bacilli, but carbapenem-resistant A baumannii (CRAB) has now emerged. The aim of this study was to determine the incidence, outcomes,...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Kim YJ,Kim SI,Lee YD,Choi HJ,Choi JY,Yoon SK,You YK,Kim DG

    更新日期:2018-05-01 00:00:00

  • Magnetic resonance imaging of hyaline cartilage regeneration in neocartilage graft implantation.

    abstract:BACKGROUND:The purpose of this study was to investigate the regenerative potential of hyaline cartilage in a neocartilage graft implant with the aid of MR cartilage imaging using a rabbit model. METHODS:Surgical osteochondral defects were created in the femoral condyles of 30 mature New Zealand rabbits. The findings o...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Tan CF,Ng KK,Ng SH,Cheung YC

    更新日期:2003-12-01 00:00:00

  • Mycobacterium abscessus infection in transplant recipients.

    abstract:BACKGROUND:Mycobacterium abscessus is a ubiquitous, rapidly growing mycobacterium that colonizes organic surfaces. It is a potential pathogen, especially in immunosuppressed patients, including transplant recipients in whom disease can range from localized cutaneous lesions to disseminated infections. The purpose of th...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Morales P,Gil A,Santos M

    更新日期:2010-10-01 00:00:00

  • Solid Organ Transplantation Activities Evolution in Brazil: Analysis of 20 Years.

    abstract:BACKGROUND:From 1968 until 1997, transplantation-related activities were not properly regulated and were informally practiced. During 20 years, many legal and political changes influenced it. OBJECTIVE:To provide a historical overview of the 20 years with a descriptive data analysis of a 20-year data set. METHODOLOGY...

    journal_title:Transplantation proceedings

    pub_type: 历史文章,杂志文章


    authors: de Oliveira Mota D,Monteleone JP,Erbs Pessoa JL,de Aguiar Roza B,Schirmer J,Stipkovic A,Frade Magalhães Girardin Pimentel C

    更新日期:2020-06-01 00:00:00

  • Antiretroviral and immunosuppressive drug-drug interactions in human immunodeficiency virus-infected liver and kidney transplant recipients.

    abstract::Highly active antiretroviral therapy (HAART) has significantly reduced mortality, and prolonged life expectancy of human immunodeficiency virus (HIV)-positive patients. Such improvements have led to increasing numbers of HIV-infected patients with end-stage organ disease as potential candidates for transplantation. A ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Marfo K,Greenstein S

    更新日期:2009-11-01 00:00:00

  • Information channels and the dynamics of uptake of living kidney donors: a retrospective study in a reference area.

    abstract:INTRODUCTION:Activity in renal transplantation at our center continues to grow due to the gradual increase in living donor kidney transplantations (LDKT). Our objective was to describe the generation process of living donation in our area of influence including two provinces and 18 chronic kidney disease (CKD) treatmen...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Vidal Blandino M,Gentil Govantes MA,Cabello Chaves V,Pereira Palomo P,Bernal Blanco G,Gonzalez Roncero FM,Fijo Viota J,Medina López R

    更新日期:2011-07-01 00:00:00

  • Effects of Ischemic Preconditioning and Postconditioning in a Renal Ischemia-Reperfusion Injury Model: A Comparative Experimental Study in Rats.

    abstract:BACKGROUND:Ischemia-reperfusion injury is an unavoidable aspect of transplantation, as well as an important cause of acute kidney injury in clinical practice. Pre- and post-ischemic conditioning are strategies that may provide organs with resistance to major ischemic events. This study evaluates the effects of ischemic...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Arantes VM,Bueno RT,Módolo RP,Domingues MAC,de Carvalho LR,do Nascimento Junior P,Módolo NSP

    更新日期:2018-12-01 00:00:00

  • Anesthetic concerns in lung transplantation for severe pulmonary hypertension.

    abstract::Lung transplantation has become a consolidated treatment for patients with severe pulmonary hypertension (PH). Several difficulties are encountered during the procedure in such candidates, who are still recognized as more severely affected by perioperative morbility and mortality than those undergoing lung transplanta...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Feltracco P,Serra E,Barbieri S,Salvaterra F,Rizzi S,Furnari M,Brezzi M,Rea F,Ori C

    更新日期:2007-07-01 00:00:00

  • Period of Hyperbaric Oxygen Delivery Leads to Different Degrees of Hepatic Ischemia/Reperfusion Injury in Rats.

    abstract:BACKGROUND:This study evaluated the morphology of the rat liver when hyperbaric oxygen (HBO) was used at various stages of ischemia and reperfusion. METHODS:Thirty-two male Wistar rats, subjected to 30 minutes of hepatic ischemia and 30 minutes of reperfusion, were randomly assigned as follows: GIR (n = 8), control wi...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Chaves JC,Neto FS,Ikejiri AT,Bertoletto PR,Teruya R,Santos Simões R,Tikazawa EH,Liu JB,Carrara FL,Taha MO,Fagundes DJ

    更新日期:2016-03-01 00:00:00

  • Patient with liver epithelioid hemangioendothelioma treated by transplantation: 3 years' observation.

    abstract::Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin, but unknown etiology that occurs in the liver, lungs and other organs. Its hepatic form (HEHE) generally behaves as a low-grade malignant tumor with a slowly progressive phenotype. Surgical resection or liver transplantation (OLT) has been r...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Mucha K,Foroncewicz B,Zieniewicz K,Nyckowski P,Krawczyk M,Cyganek A,Paczek L

    更新日期:2006-01-01 00:00:00

  • Living related liver transplantation for hepatocellular carcinoma in Egypt.

    abstract:BACKGROUND:Living related liver transplantation (LRLT) for hepatocellular carcinoma (HCC) in cirrhotic patients has emerged as a rewarding therapy for a cure. Extensions of the Milan criteria have been proposed with encouraging results. PATIENTS AND METHODS:From October 2001 to June 2004, 47 adult patients with end-st...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: El-Meteini M,Fayez A,Fathy M,Abdalaal A,Safaan H,Mostafa I,Abdalaal M,Mokhtar A,Salah M,El-Dorry A,Abdalwahab S,El-Monayeri M,Boillot O

    更新日期:2005-09-01 00:00:00

  • Anemia and Immunosuppressive Regimen in Renal Transplanted Patients: Single-Center Retrospective Study.

    abstract::We compared retrospectively the level of hemoglobin and the percentage of patients with anemia among 59 kidney transplant recipients receiving everolimus, cyclosporine, and corticosteroids and 128 treated with cyclosporine, mycophenolic acid, and corticosteroids. We also compared age at the time of transplantation, se...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Carta P,Bigazzi B,Buti E,Antognoli G,Di Maria L,Caroti L,Minetti EE

    更新日期:2016-03-01 00:00:00

  • Urologic complications in 1523 renal transplantations: The Baskent University experience.

    abstract::Urologic complications, observed since the beginning of renal transplantation, cause significant morbidity and mortality. In the first few years the procedure was performed, incidence of urologic complications was reported to be 10% to 25%. Recently, the incidence of urologic complications after renal transplantation ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Dalgic A,Boyvat F,Karakayali H,Moray G,Emiroglu R,Haberal M

    更新日期:2006-03-01 00:00:00

  • The reduction of hypoxia-induced and reoxygenation-induced apoptosis in rat islets by epigallocatechin gallate.

    abstract::The survival of transplanted tissue is affected by the detrimental consequences of hypoxia followed by reoxygenation. The majority of transplanted cells undergo apoptosis due to hypoxia and reoxygenation (H/R) injury, but protection from H/R has been less examined. In this study, we examined whether epigallocatechin g...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Hara Y,Fujino M,Adachi K,Li XK

    更新日期:2006-10-01 00:00:00

  • Conversion to proliferation signal inhibitors-based immunosuppressive regimen in kidney transplantation: to whom and when?

    abstract:BACKGROUND:Despite significant advances in kidney transplantation, long-term graft survival has not dramatically improved leading to strategies to change immunosuppression during the posttransplantation period. Proliferation signal inhibitors (PSI) sirolimus or everolimus possess immunosuppressive and antiproliferative...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Sahin S,Gürkan A,Uyar M,Dheir H,Turunç V,Varilsuha C,Kaçar S

    更新日期:2011-04-01 00:00:00

  • Agonal period in potential non-heart-beating donors.

    abstract::The shortage of donor kidneys for renal transplantation is becoming more severe as the gap between the number of patients waiting for renal transplantation and the number of cadaveric organs available continues to widen. Therefore, many centres have started using non-heart-beating (NHB) donors. There was no clear plan...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Sohrabi S,Navarro A,Asher J,Wilson C,Sanni A,Wyrley-Birch H,Anand V,Reddy M,Rix D,Jacques B,Manas D,Talbot D

    更新日期:2006-10-01 00:00:00

  • Exchange donor transplantation: ethical option for living renal transplantation.

    abstract:PURPOSE:Taking in consideration the opinion of our team, which necessitates obligation of a relative relation between donors and recipients (genetic or matrimonial), we performed donor exchanges as an ethical alternative in living donor transplantations. We reviewed the outcomes of our exchange series. METHODS:Between...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gürkan A,Kaçar S,Varılsuha C,Tilif S,Turunç V,Doǧan M,Dheir H,Sahin S

    更新日期:2011-04-01 00:00:00

  • SNPs Within the MTOR Gene Are Associated With an Increased Risk of Developing De Novo Diabetes Mellitus Following the Administration of Everolimus in Liver Transplant Recipients.

    abstract:BACKGROUND:The impact of immunosuppressive drugs in patients following liver transplantation (LT) is very individual. Despite the multiple beneficial effects of the mammalian target of rapamycin (mTOR) inhibitor everolimus (EVR) in LT recipients, some patients do not benefit from EVR administration. We investigated whe...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Husen P,Straub K,Willuweit K,Hagemann A,Wedemeyer H,Bachmann HS,Herzer K

    更新日期:2019-01-01 00:00:00