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Dendritic cell therapy in composite tissue allotransplantation.

Abstract：

:Dendritic cells (DCs) are bone marrow-derived, professional antigen-presenting cells, with inherent tolerogenic function. The ability of immature or maturation-resistant DCs to regulate alloantigen-specific T-cell responses and to promote tolerance induction has been well demonstrated in organ and bone marrow transplantation. Recent data suggest that DCs can also promote long-term survival of composite tissue allografts in the absence of continued immunosuppressive drug therapy.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Thomson AW,Sacks JM,Kuo YR,Ikeguchi R,Horibe EK,Unadkat J,Solari MG,Feili-Hariri M,Lee WP

doi

10.1016/j.transproceed.2009.01.011

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

537-8

issue

2

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(09)00012-8

journal_volume

41

pub_type

杂志文章

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