Hemophagocytic Syndrome as Uncommon Cause of Severe Pancytopenia After Liver Transplantation.

Abstract:

BACKGROUND:A rare but life-threatening cause of pancytopenia after liver transplantation is hemophagocytic syndrome. We present a 48-year-old woman who underwent liver transplantation and developed a hemophagocytic syndrome secondary to Epstein-Barr virus with a fatal course, despite initial treatment with immunosuppressants. The diagnosis was made based on the bone marrow aspiration, in which macrophages with phagocytic activity were observed, and clinical findings. Due to the very poor outcomes and high mortality, in patients with severe pancytopenia hemophagocytic syndrome should be excluded, and a bone marrow aspiration should be considered.

journal_name

Transplant Proc

authors

Valenzuela EF,García AC,García-Pajares F,Tejada JT,Muñoz RN,Martín CM,Delgado LS,Martín CA,Álvarez CA,Fernández-Fontecha E,Sánchez-Antolín G

doi

10.1016/j.transproceed.2020.02.060

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

1500-1502

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(20)30254-2

journal_volume

52

pub_type

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