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Association Between Dyspnea and Severity of Liver Disease in Patients in the Pre-transplantation Period-A Pilot Study.

Abstract：

BACKGROUND:Liver transplantation is indicated at the end stage of chronic liver failure, and severity of disease will determine the precocity of this happening. At this stage, the presence of chronic dyspnea is one of several manifestations of progression of the disease, which leads the patient to inactivity. A rehabilitation program can positively influence the evolution of liver transplant recipients. The objective of this study was to establish an association between the perception of dyspnea and the severity of liver disease in patients at a single center of a Brazilian liver pre-transplantation clinic. METHODS:Measurements were performed at a liver pre-transplantation clinic. The severity of liver disease was assessed with the use of the Model for End-Stage Liver Disease (MELD) score, and dyspnea was assessed with the use of a modified Medical Research Council scale of dyspnea (mMRC). RESULTS:Men had a higher prevalence of viral hepatitis. Dyspnea was reported only during intense exercise. Duration of disease and MELD score showed medians of 49 months and 20, respectively. CONCLUSIONS:We found no correlation between mMRC and the MELD score. In addition, no correlation was found between duration of disease and MELD score or mMRC.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Monte da Silva AG,deA Roza Aguiar B,Chiavegato LD

doi

10.1016/j.transproceed.2016.06.027

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

2328-2332

issue

7

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(16)30319-0

journal_volume

48

pub_type

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