The Jacobian as a measure of planar dose congruence.

Abstract:

:We propose a new starting point for comparing planar dose distributions using a Jacobian-based measure. The measure is normalization independent, i.e., is sensitive to dose patterns while not being biased by global dose scaling. The measure is free of tunable parameters and is bounded between zero and one. We also propose an integrated version of the measure, normalized over the integrated area: the Jacobian index. We demonstrate analytically and verified numerically that the Jacobian index tends to a unique value of 2/pi when comparing unrelated dose distributions. We present a preliminary demonstration of the sensitivity and general characteristics of this measure. Examples of intensity modulated photon dose distributions from a linac as predicted with the convolution-superposition algorithm for various scenarios of irradiation mismatch and a film measured distribution are compared.

journal_name

Med Phys

journal_title

Medical physics

authors

Paniak LD,Charland PM

doi

10.1118/1.2982136

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

4967-73

issue

11

eissn

0094-2405

issn

2473-4209

journal_volume

35

pub_type

杂志文章
  • Material-specific analysis using coherent-scatter imaging.

    abstract::Coherent-scatter computed tomography (CSCT) is a novel imaging method we are developing to produce cross-sectional images based on the low-angle (<10 degrees) scatter properties of tissue. At diagnostic energies, this scatter is primarily coherent with properties dependent upon the molecular structure of the scatterer...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1493216

    authors: Batchelar DL,Cunningham IA

    更新日期:2002-08-01 00:00:00

  • Efficient low-dose CT artifact mitigation using an artifact-matched prior scan.

    abstract:PURPOSE:Low-dose CT has attracted increasing attention due to growing concerns about radiation exposure in medical scans. However, the frugal use of x-ray radiation inevitably reduces the quality of the CT images, introducing artifacts such as noise and streaks which make the reconstructed images difficult to read in c...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736528

    authors: Xu W,Mueller K

    更新日期:2012-08-01 00:00:00

  • Thermoacoustic molecular tomography with magnetic nanoparticle contrast agents for targeted tumor detection.

    abstract:PURPOSE:The primary feasibility steps of demonstrating the ability of microwave-induced thermoacoustic (TA) in phantoms have been previously reported. However, none were shown to target a diseased site in living subjects in thermoacoustic tomography (TAT) field so far. To determine the expressions of oncogenic surface ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3466696

    authors: Nie L,Ou Z,Yang S,Xing D

    更新日期:2010-08-01 00:00:00

  • A template-based approach to semi-quantitative SPECT myocardial perfusion imaging: Independent of normal databases.

    abstract:PURPOSE:Normal patient databases (NPDs) are used to distinguish between normal and abnormal perfusion in SPECT myocardial perfusion imaging (MPI) and have gained wide acceptance in the clinical environment, yet there are limitations to this approach. This study introduces a template-based method for semi-quantitative M...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3595112

    authors: Hughes T,Shcherbinin S,Celler A

    更新日期:2011-07-01 00:00:00

  • Detection nonuniformity measurements and corrections for cone beam transmission CT on a gamma camera.

    abstract::Cone beam transmission CT (CB-CT) improves SPECT imaging by providing high-quality attenuation maps for attenuation compensation and for correlated SPECT and CT imaging. The present work measures the detection nonuniformity for CB-CT implemented with a gamma camera, and applies nonuniformity corrections to make CB-CT ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596838

    authors: Manglos SH,Capone RB,Bassano DA

    更新日期:1992-03-01 00:00:00

  • Registration of central paths and colonic polyps between supine and prone scans in computed tomography colonography: pilot study.

    abstract::Computed tomography colonography (CTC) is a minimally invasive method that allows the evaluation of the colon wall from CT sections of the abdomen/pelvis. The primary goal of CTC is to detect colonic polyps, precursors to colorectal cancer. Because imperfect cleansing and distension can cause portions of the colon wal...

    journal_title:Medical physics

    pub_type: 临床试验,杂志文章

    doi:10.1118/1.1796171

    authors: Li P,Napel S,Acar B,Paik DS,Jeffrey RB Jr,Beaulieu CF

    更新日期:2004-10-01 00:00:00

  • Monte Carlo calculation of output factors for circular, rectangular, and square fields of electron accelerators (6-20 MeV).

    abstract::Monte Carlo (MC) techniques can be used to build a simulation model of an electron accelerator to calculate output factors for electron fields. This can be useful during commissioning of electron beams from a linac and in clinical practice where irregular fields are also encountered. The Monte Carlo code BEAM/EGS4 was...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1373402

    authors: Verhaegen F,Mubata C,Pettingell J,Bidmead AM,Rosenberg I,Mockridge D,Nahum AE

    更新日期:2001-06-01 00:00:00

  • Effects of tumor motion in GRID therapy.

    abstract::Clinical and biological evidence suggest that the success of GRID therapy in debulking large tumors depends on the high peak-to-valley contrast in the dose distribution. In this study, we show that the peaks and valleys can be significantly blurred out by respiration-induced tumor motion, possibly affecting the clinic...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2977538

    authors: Naqvi SA,Mohiuddin MM,Ha JK,Regine WF

    更新日期:2008-10-01 00:00:00

  • Calculation of photon dose distributions in an inhomogeneous medium using convolutions.

    abstract::A formulation of the single energy photon transport problem is cast in the form of a series of convolutions over the primary fluence distribution with invariant kernels. A method is developed for compensating for the variant intervoxel attenuation in the scattered dose distribution by means of an invariant correction ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595964

    authors: Boyer AL,Mok EC

    更新日期:1986-07-01 00:00:00

  • A practical technique for verification of three-dimensional conformal dose distributions in stereotactic radiosurgery.

    abstract::The trend toward conformal techniques in stereotactic radiosurgery necessitates an accurate and practical method for verification of irregular three-dimensional dose distributions. This work presents the design and evaluation of a phantom system facilitating the measurement of conformal dose distributions using one or...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598962

    authors: Robar JL,Clark BG

    更新日期:2000-05-01 00:00:00

  • Real-time distortionless high-factor compression scheme.

    abstract::Nowadays, digital subtraction angiography systems must be able to sustain real-time acquisition (30 frames per second) of 512 x 512 x 8 bit images and store several sequences of such images on low cost and general-purpose mass memories. Concretely, that means a 7.8 Mbytes per second rate and about 780 Mbytes disk spac...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596309

    authors: Liénard J

    更新日期:1989-11-01 00:00:00

  • The properties of the ultramicrocylindrical ionization chamber for small field used in stereotactic radiosurgery.

    abstract::Accurate dosimetry of small-field photon beams tends to be difficult to perform due to the presence of lateral electronic disequilibrium and steep dose gradients. In stereotactic radiosurgery (SRS), small fields of 6-30 mm in diameter are used. Generally thermoluminescence dosimetry chips, Farmer, Thimble ion chamber,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1350437

    authors: Vahc YW,Chung WK,Park KR,Lee JY,Lee YH,Kwon O,Kim S

    更新日期:2001-03-01 00:00:00

  • A respiratory-gated treatment system for proton therapy.

    abstract::Proton therapy offers the potential for excellent dose conformity and reduction in integral dose. The superior dose distribution is, however, much more sensitive to changes in radiological depths along the beam path than for photon fields. Respiratory motion can cause such changes for treatments sites like lung, liver...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2756602

    authors: Lu HM,Brett R,Sharp G,Safai S,Jiang S,Flanz J,Kooy H

    更新日期:2007-08-01 00:00:00

  • Effect of respiratory motion on the delivery of breast radiotherapy using SMLC intensity modulation.

    abstract::This study evaluates the effects of respiratory motion on breast radiotherapy delivered using segmented multileaf collimator (SMLC) intensity modulation. An anthropomorphic breast phantom was constructed of polystyrene plates between which radiographic films were inserted. The phantom was mounted on a moving platform ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2405323

    authors: Liu Q,McDermott P,Burmeister J

    更新日期:2007-01-01 00:00:00

  • Sparse and optimal acquisition design for diffusion MRI and beyond.

    abstract:PURPOSE:Diffusion magnetic resonance imaging (MRI) in combination with functional MRI promises a whole new vista for scientists to investigate noninvasively the structural and functional connectivity of the human brain-the human connectome, which had heretofore been out of reach. As with other imaging modalities, diffu...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3700166

    authors: Koay CG,Ozarslan E,Johnson KM,Meyerand ME

    更新日期:2012-05-01 00:00:00

  • Skeletal dosimetry in cone beam computed tomography.

    abstract::Cone beam computed tomography (CBCT) is a relatively new patient imaging technique that has proved invaluable for treatment target verification and patient positioning during image-guided radiotherapy (IGRT). It has been shown that CBCT results in additional dose to bone that may amount to 10% of the prescribed dose. ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3147143

    authors: Walters BR,Ding GX,Kramer R,Kawrakow I

    更新日期:2009-07-01 00:00:00

  • Iterative metal artifact reduction for x-ray computed tomography using unmatched projector/backprojector pairs.

    abstract:PURPOSE:Metal artifact reduction (MAR) is a major problem and a challenging issue in x-ray computed tomography (CT) examinations. Iterative reconstruction from sinograms unaffected by metals shows promising potential in detail recovery. This reconstruction has been the subject of much research in recent years. However,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4950722

    authors: Zhang H,Wang L,Li L,Cai A,Hu G,Yan B

    更新日期:2016-06-01 00:00:00

  • Clinical use of EBT model Gafchromic film in radiotherapy.

    abstract::The Gafchromic EBT was recently introduced in film dosimetry for external beam therapy (EBT). The high spatial resolution, weak energy dependence, and near-tissue equivalence of EBT films make them suitable for measurement of dose distributions in radiotherapy, especially intensity-modulated radiation therapy (IMRT). ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2362876

    authors: Fiandra C,Ricardi U,Ragona R,Anglesio S,Giglioli FR,Calamia E,Lucio F

    更新日期:2006-11-01 00:00:00

  • Computer dosimetry of 192Ir wire.

    abstract::The dosimetry of 192Ir linear sources with a commercial treatment planning computer system has been evaluated. Reference dose rate data were selected from the literature and normalized in a manner consistent with our clinical and dosimetric terminology. The results of the computer calculations are compared to the refe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595685

    authors: Kline RW,Gillin MT,Grimm DF,Niroomand-Rad A

    更新日期:1985-09-01 00:00:00

  • First study of on-treatment volumetric imaging during respiratory gated VMAT.

    abstract:PURPOSE:To obtain on-treatment volumetric patient anatomy during respiratory gated volumetric modulated arc therapy (VMAT). METHODS:On-board imaging device integrated with Linacs offers a viable tool for obtaining patient anatomy during radiation treatment delivery. In this study, the authors acquired beam-level kV im...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.4794925

    authors: Choi K,Xing L,Koong A,Li R

    更新日期:2013-04-01 00:00:00

  • Experimental assessment of microwave ablation computational modeling with MR thermometry.

    abstract:PURPOSE:Computational models are widely used during the design and characterization of microwave ablation (MWA) devices, and have been proposed for pretreatment planning. Our objective was to assess three-dimensional (3D) transient temperature and ablation profiles predicted by MWA computational models with temperature...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14318

    authors: Faridi P,Keselman P,Fallahi H,Prakash P

    更新日期:2020-09-01 00:00:00

  • Monte Carlo calculation of the maximum therapeutic gain of tumor antivascular alpha therapy.

    abstract:PURPOSE:Metastatic melanoma lesions experienced marked regression after systemic targeted alpha therapy in a phase 1 clinical trial. This unexpected response was ascribed to tumor antivascular alpha therapy (TAVAT), in which effective tumor regression is achieved by killing endothelial cells (ECs) in tumor capillaries ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3681010

    authors: Huang CY,Oborn BM,Guatelli S,Allen BJ

    更新日期:2012-03-01 00:00:00

  • Projections onto the Pareto surface in multicriteria radiation therapy optimization.

    abstract:PURPOSE:To eliminate or reduce the error to Pareto optimality that arises in Pareto surface navigation when the Pareto surface is approximated by a small number of plans. METHODS:The authors propose to project the navigated plan onto the Pareto surface as a postprocessing step to the navigation. The projection attempt...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4930252

    authors: Bokrantz R,Miettinen K

    更新日期:2015-10-01 00:00:00

  • Prevention of a wrong-location misadministration through the use of an intradepartmental incident learning system.

    abstract:PURPOSE:A series of examples are presented in which potential errors in the delivery of radiation therapy were prevented through use of incident learning. These examples underscore the value of reporting near miss incidents. METHODS:Using a departmental incident learning system, eight incidents were noted over a two-y...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4760774

    authors: Ford EC,Smith K,Harris K,Terezakis S

    更新日期:2012-11-01 00:00:00

  • Ultrasound contrast-detail analysis: a preliminary study in human observer performance.

    abstract::Results of a human observer performance study using a new ultrasound contrast-detail (CD) phantom are reported. The new phantom allows estimates of the fundamental statistical uncertainties involved in CD analysis. Results of these experiments show that observers generally considered to be "trained" require experience...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597147

    authors: Hall TJ,Insana MF,Soller NM,Harrison LA

    更新日期:1993-01-01 00:00:00

  • Nonlinear magnetic stereotaxis: three-dimensional, in vivo remote magnetic manipulation of a small object in canine brain.

    abstract::In a series of in vivo experiments on five adult canines, a small cylindrical permanent magnet (approximately 5-mm diameter x 5 mm long) was magnetically moved under fluoroscopic guidance from an occipital-lobe burr hole to a predetermined destination within the brain and then removed. On three of the animals, dorsal ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596520

    authors: Grady MS,Howard MA 3rd,Molloy JA,Ritter RC,Quate EG,Gillies GT

    更新日期:1990-05-01 00:00:00

  • Multipinhole collimator with 20 apertures for a brain SPECT application.

    abstract:PURPOSE:Several new technologies for single photon emission computed tomography (SPECT) instrumentation with parallel-hole collimation have been proposed to improve detector sensitivity and signal collection efficiency. Benefits from improved signal efficiency include shorter acquisition times and lower dose requiremen...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4897567

    authors: Lee TC,Ellin JR,Huang Q,Shrestha U,Gullberg GT,Seo Y

    更新日期:2014-11-01 00:00:00

  • Sci-Fri AM: Imaging - 05: Cone-beam computed tomography for breast biopsy analysis: Simulations.

    abstract:PURPOSE:To determine the feasibility and potential utility of cone beam CT on breast biopsies. METHODS:CBCT simulations were done with a setup which emulates an MX-20 digital specimen radiography system (Faxitron X-Ray Corporation, Chicago, IL), albeit a DQE = 1 was assumed. The phantom consisted of a 5mm diameter cyl...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740191

    authors: Laamanen C,LeClair R

    更新日期:2012-07-01 00:00:00

  • Quantitative ultrasound characterization of locally advanced breast cancer by estimation of its scatterer properties.

    abstract:PURPOSE:Tumor grading is an important part of breast cancer diagnosis and currently requires biopsy as its standard. Here, the authors investigate quantitative ultrasound parameters in locally advanced breast cancers that can potentially separate tumors from normal breast tissue and differentiate tumor grades. METHODS...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4852875

    authors: Tadayyon H,Sadeghi-Naini A,Wirtzfeld L,Wright FC,Czarnota G

    更新日期:2014-01-01 00:00:00

  • Validation of a method for in vivo 3D dose reconstruction for IMRT and VMAT treatments using on-treatment EPID images and a model-based forward-calculation algorithm.

    abstract:PURPOSE:Radiation treatments are trending toward delivering higher doses per fraction under stereotactic radiosurgery and hypofractionated treatment regimens. There is a need for accurate 3D in vivo patient dose verification using electronic portal imaging device (EPID) measurements. This work presents a model-based te...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4935199

    authors: Van Uytven E,Van Beek T,McCowan PM,Chytyk-Praznik K,Greer PB,McCurdy BM

    更新日期:2015-12-01 00:00:00