Regulation of Sendai virus transcription: evidence for a single promoter in vivo.

Abstract:

:The synthesis of Sendai virus RNA species was examined after UV irradiation of cells late in infection. Compared with the inactivation of 50S genomic RNA synthesis, the synthesis of the group of mRNA species that sediments at 18S was inactivated at an average rate consistent with a process of sequential transcription from a single promoter. The rates of inactivation of the synthesis of individual mRNA's separated by polyacrylamide gel electrophoresis confirmed this and, with the aid of additional data, suggested that the order of genes in the Sendai virus genome is: 3'-NP-Fo-M-P-HM-L-5'.

journal_name

J Virol

journal_title

Journal of virology

authors

Glazier K,Raghow R,Kingsbury DW

doi

10.1128/JVI.21.3.863-871.1977

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

863-71

issue

3

eissn

0022-538X

issn

1098-5514

journal_volume

21

pub_type

杂志文章
  • Cottontail rabbit papillomavirus E8 protein is essential for wart formation and provides new insights into viral pathogenesis.

    abstract::The cottontail rabbit papillomavirus (CRPV) a and b subtypes display a conserved E8 open reading frame encoding a 50-amino-acid hydrophobic protein, with structural similarities to the E5 transmembrane oncoprotein of genital human PVs (HPVs). CRPV E8 has been reported to play a role in papilloma growth but not to be e...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.80.10.4890-4900.2006

    authors: Nonnenmacher M,Salmon J,Jacob Y,Orth G,Breitburd F

    更新日期:2006-05-01 00:00:00

  • The alkylated imino sugar, n-(n-Nonyl)-deoxygalactonojirimycin, reduces the amount of hepatitis B virus nucleocapsid in tissue culture.

    abstract::n-(n-Nonyl)-deoxygalactonojirimycin (n,n-DGJ), an alkylated imino sugar, reduces the amount of HBV DNA produced within the stably transfected HBV-producing HepG2.2.15 line in culture and is under consideration for development as a human therapeutic. n,n-DGJ does not appear to inhibit HBV DNA polymerase activity or env...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.77.22.11933-11940.2003

    authors: Lu X,Tran T,Simsek E,Block TM

    更新日期:2003-11-01 00:00:00

  • Wild-type measles virus with the hemagglutinin protein of the edmonston vaccine strain retains wild-type tropism in macaques.

    abstract::A major difference between vaccine and wild-type strains of measles virus (MV) in vitro is the wider cell specificity of vaccine strains, resulting from the receptor usage of the hemagglutinin (H) protein. Wild-type H proteins recognize the signaling lymphocyte activation molecule (SLAM) (CD150), which is expressed on...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.06517-11

    authors: Takeuchi K,Nagata N,Kato SI,Ami Y,Suzaki Y,Suzuki T,Sato Y,Tsunetsugu-Yokota Y,Mori K,Van Nguyen N,Kimura H,Nagata K

    更新日期:2012-03-01 00:00:00

  • The v-erbB oncogene confers enhanced cellular susceptibility to reovirus infection.

    abstract::We have previously demonstrated that two mouse cell lines that are poorly infectible by reovirus become highly susceptible upon transfection with the gene encoding the epidermal growth factor receptor (EGFR) (J. E. Strong, D. Tang, and P. W. K. Lee, Virology 197:405-411, 1993). This enhancement of infection efficiency...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.70.1.612-616.1996

    authors: Strong JE,Lee PW

    更新日期:1996-01-01 00:00:00

  • Roles of macrophages in measles virus infection of genetically modified mice.

    abstract::Knowledge of the mechanisms of virus dissemination in acute measles is cursory, but cells of the monocyte/macrophage (MM) lineage appear to be early targets. We characterized the dissemination of the Edmonston B vaccine strain of measles virus (MV-Ed) in peripheral blood mononuclear cells (PBMC) of two mouse strains e...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.75.7.3343-3351.2001

    authors: Roscic-Mrkic B,Schwendener RA,Odermatt B,Zuniga A,Pavlovic J,Billeter MA,Cattaneo R

    更新日期:2001-04-01 00:00:00

  • Intragenic complementation between temperature-sensitive mutants of gene 42 (dCMP hydroxymethylase) of bacteriophage T4.

    abstract::Interallelic complementation between certain temperature-sensitive mutants of gene 42 of bacteriophage T4 was demonstrated by measuring the incorporation of labeled thymine into DNA. ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.12.2.415-416.1973

    authors: Chiu CS,Greenberg GR

    更新日期:1973-08-01 00:00:00

  • Phosphorylation of NS protein by vesicular stomatitis virus nucleocapsids: lack of effect during RNA synthesis and separation of kinase from L protein.

    abstract::The relationship between NS protein phosphorylation and RNA polymerase activities was determined in nucleocapsids purified from vesicular stomatitis virus grown in BHK cells. Phosphate incorporation into endogenous NS protein under transcription conditions reached a maximum value of 0.06 mol/mol of NS within 20 to 30 ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.64.7.3259-3264.1990

    authors: Massey DM,Deans N,Lenard J

    更新日期:1990-07-01 00:00:00

  • Characterization of the minimal DNA binding domain of the human papillomavirus e1 helicase: fluorescence anisotropy studies and characterization of a dimerization-defective mutant protein.

    abstract::The E1 helicase of papillomaviruses is required for replication of the viral double-stranded DNA genome, in conjunction with cellular factors. DNA replication is initiated at the viral origin by the assembly of E1 monomers into oligomeric complexes that have unwinding activity. In vivo, this process is catalyzed by th...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.77.9.5178-5191.2003

    authors: Titolo S,Brault K,Majewski J,White PW,Archambault J

    更新日期:2003-05-01 00:00:00

  • Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA.

    abstract::Mice and cattle injected with plasmids encoding bovine herpesvirus 1 (BHV-1) glycoproteins developed gene-specific antibody responses capable of neutralizing BHV-1. The ability of animals to respond serologically to DNA injections was in part dependent on the quantity of DNA injected and was also negatively affected b...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.67.9.5664-5667.1993

    authors: Cox GJ,Zamb TJ,Babiuk LA

    更新日期:1993-09-01 00:00:00

  • Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.

    abstract::To assess whether nitric oxide synthase 2 (NOS2) fulfills the criteria of an innate resistance locus against an acute viral infection, we inoculated genetically deficient NOS2-/- mice with virulent ectromelia virus (EV), the causative agent of mousepox. NOS2-/- mice proved highly susceptible to EV yet showed no diminu...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.72.9.7703-7706.1998

    authors: Karupiah G,Chen JH,Nathan CF,Mahalingam S,MacMicking JD

    更新日期:1998-09-01 00:00:00

  • Molecular genetic analysis of Epstein-Barr virus Cp promoter function.

    abstract::The Cp promoter of Epstein-Barr virus (EBV) directs most transcription of the EBNA genes in lymphoblastoid cell lines. The functions of two control regions in the Cp promoter have been studied by construction of recombinant EBV strains containing specific mutations in these elements. Mutation of the RBP-Jk (CBF1) bind...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.70.3.1695-1705.1996

    authors: Evans TJ,Farrell PJ,Swaminathan S

    更新日期:1996-03-01 00:00:00

  • Uniform nomenclature for monoclonal antibodies directed against virus-coded proteins of simian virus 40 and polyoma virus.

    abstract::A uniform nomenclature has been agreed upon for monoclonal antibodies directed against virus-coded proteins of simian virus 40 and polyoma virus. Blocks of numbers from PAb1 to PAb999 have been allocated to workers involved in the isolation of monoclonal antibodies of this type. The correspondence between PAb numbers ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.41.2.709-709.1982

    authors: Crawford L,Harlow E

    更新日期:1982-02-01 00:00:00

  • RIII/Sa mice with a high incidence of mammary tumors express two exogenous strains and one potential endogenous strain of mouse mammary tumor virus.

    abstract::The inbred mouse strain RIII has long been known for shedding large amounts of mouse mammary tumor virus (MMTV) particles in milk and for the development of hormone-dependent early mammary tumors at a very high incidence (>90%). We have established one RIII subline (RIII/Sa) that shows a pattern of virus expression an...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/jvi.78.2.1055-1062.2004

    authors: Sarkar NH,Golovkina T,Uz-Zaman T

    更新日期:2004-01-01 00:00:00

  • The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A).

    abstract::The influenza virus NS1 protein inhibits the nuclear export of a spliced viral mRNA, NS2 mRNA (F. V. Alonso-Caplen, M. E. Nemeroff, Y. Qiu, and R. M. Krug, Genes Dev. 6:255-267, 1992). To identify the sequence in NS2 mRNA that is recognized by the NS1 protein, we developed a gel shift assay for the formation of specif...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.68.4.2425-2432.1994

    authors: Qiu Y,Krug RM

    更新日期:1994-04-01 00:00:00

  • The unique stacked rings in the nucleocapsid of the white spot syndrome virus virion are formed by the major structural protein VP664, the largest viral structural protein ever found.

    abstract::One unique feature of the shrimp white spot syndrome virus (WSSV) genome is the presence of a giant open reading frame (ORF) of 18,234 nucleotides that encodes a long polypeptide of 6,077 amino acids with a hitherto unknown function. In the present study, by applying proteomic methodology to analyze the sodium dodecyl...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.79.1.140-149.2005

    authors: Leu JH,Tsai JM,Wang HC,Wang AH,Wang CH,Kou GH,Lo CF

    更新日期:2005-01-01 00:00:00

  • A cowpox virus gene required for multiplication in Chinese hamster ovary cells.

    abstract::Cowpox virus, in contrast to vaccinia virus, can multiply in Chinese hamster ovary cells. To study the genetic basis for this difference in host range, recombinants between vaccinia and cowpox viruses were isolated and their DNA restriction patterns were examined. The ability to multiply in Chinese hamster ovary cells...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.62.4.1297-1304.1988

    authors: Spehner D,Gillard S,Drillien R,Kirn A

    更新日期:1988-04-01 00:00:00

  • Similar patterns of infection with bovine foamy virus in experimentally inoculated calves and sheep.

    abstract::Foamy viruses (FVs) are the least known retroviruses commonly found in primates, cats, horses, and cattle. Although FVs are considered apathogenic, simian and feline FVs have been shown to be associated with some transient health abnormalities in animal models. Currently, data regarding the course of infection with bo...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02447-12

    authors: Materniak M,Hechler T,Löchelt M,Kuzmak J

    更新日期:2013-03-01 00:00:00

  • Mechanisms of antiviral immunity induced by a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: cytotoxic T cells.

    abstract::We used a transfected L cell and a vaccinia vector carrying the herpes simplex virus type 1 (HSV-1) gene coding for glycoprotein D (gD) to characterize HSV-specific T-cell responses. Various studies with mice revealed that the vectors could stimulate some HSV-specific T-cell responses. Although the majority of the T c...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.61.3.726-734.1987

    authors: Martin S,Moss B,Berman PW,Laskey LA,Rouse BT

    更新日期:1987-03-01 00:00:00

  • Increased immunogenicity of human immunodeficiency virus gp120 engineered to express Galalpha1-3Galbeta1-4GlcNAc-R epitopes.

    abstract::The glycan shield comprised of multiple carbohydrate chains on the human immunodeficiency virus (HIV) envelope glycoprotein gp120 helps the virus to evade neutralizing antibodies. The present study describes a novel method for increasing immunogenicity of gp120 vaccine by enzymatic replacement of sialic acid on these ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00310-06

    authors: Abdel-Motal U,Wang S,Lu S,Wigglesworth K,Galili U

    更新日期:2006-07-01 00:00:00

  • Cloning and analysis of integrated hepatitis virus sequences from a human hepatoma cell line.

    abstract::We report here the isolation by molecular cloning and the analysis by heteroduplex and restriction enzyme mapping of seven distinct DNA fragments containing hepatitis B virus (HBV) sequences from genomic DNA of the PLC/PRF/5 human liver carcinoma cell line (the Alexander cell). No intact full-length HBV genomes were p...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.51.3.776-787.1984

    authors: Shaul Y,Ziemer M,Garcia PD,Crawford R,Hsu H,Valenzuela P,Rutter WJ

    更新日期:1984-09-01 00:00:00

  • Sulfated components of enveloped viruses.

    abstract::The glycoproteins of several enveloped viruses, grown in a variety of cell types, are labeled with 35SO4(-2), whereas the nonglycosylated proteins are not. This was shown for the HN and F glycoproteins of SV5 and Sendai virus, the E1 and E2 glycoproteins of Sindbis virus, and for the major glycoprotein, gp69, as well ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.16.4.859-866.1975

    authors: Pinter A,Compans RW

    更新日期:1975-10-01 00:00:00

  • Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques.

    abstract::The basis for the switch from CCR5 to CXCR4 coreceptor usage seen in approximately 50% of human immunodeficiency virus type 1 (HIV-1) subtype B-infected individuals as disease advances is not well understood. Among the reasons proposed are target cell limitation and better immune recognition of the CXCR4 (X4)-tropic c...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00759-07

    authors: Ho SH,Tasca S,Shek L,Li A,Gettie A,Blanchard J,Boden D,Cheng-Mayer C

    更新日期:2007-08-01 00:00:00

  • Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface.

    abstract::The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly localized promiscuous regulator of viral and cellular transcription. IE1 has long been known to associate with host mitotic chromatin, yet the mechanisms underlying this interaction have not been specified. In this study,...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02606-13

    authors: Mücke K,Paulus C,Bernhardt K,Gerrer K,Schön K,Fink A,Sauer EM,Asbach-Nitzsche A,Harwardt T,Kieninger B,Kremer W,Kalbitzer HR,Nevels M

    更新日期:2014-01-01 00:00:00

  • Functional identification and analysis of cis-acting sequences which mediate genome cleavage and packaging in human herpesvirus 6.

    abstract::Sequences present at the genomic termini of herpesviruses become linked during lytic-phase replication and provide the substrate for cleavage and packaging of unit length viral genomes. We have previously shown that homologs of the consensus herpesvirus cleavage-packaging signals, pac1 and pac2, are located at the lef...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.72.1.320-329.1998

    authors: Deng H,Dewhurst S

    更新日期:1998-01-01 00:00:00

  • Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin.

    abstract::On the basis of the conservation of neuraminidase (N) active-site residues in influenza virus N and paramyxovirus hemagglutinin-neuraminidase (HN), it has been suggested that the three-dimensional (3D) structures of the globular heads of the two proteins are broadly similar. In this study, details of this structural s...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.71.8.6155-6167.1997

    authors: Langedijk JP,Daus FJ,van Oirschot JT

    更新日期:1997-08-01 00:00:00

  • Reactivation of human immunodeficiency virus type 2 in macaques after simian immunodeficiency virus SIVmac superinfection.

    abstract::By superinfection of human immunodeficiency virus type 2 (HIV-2) strain HIV-2ben-infected macaques with simian immunodeficiency virus (SIV) strain SIVmac, we investigated the mutual influences of an apathogenic and a pathogenic virus in vivo. Four rhesus and two cynomolgus monkeys were infected with HIV-2ben in 1988 a...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.69.3.1564-1574.1995

    authors: Petry H,Dittmer U,Stahl-Hennig C,Coulibaly C,Makoschey B,Fuchs D,Wachter H,Tolle T,Morys-Wortmann C,Kaup FJ

    更新日期:1995-03-01 00:00:00

  • Chimeric porcine circoviruses (PCV) containing amino acid epitope tags in the C terminus of the capsid gene are infectious and elicit both anti-epitope tag antibodies and anti-PCV type 2 neutralizing antibodies in pigs.

    abstract::A chimeric porcine circovirus (PCV1-2) with the capsid gene of pathogenic PCV2 cloned into the genomic backbone of nonpathogenic PCV1 is attenuated in pigs but elicits protective immunity against PCV2. In this study, short epitope tags were inserted into the C terminus of the capsid protein of the chimeric PCV1-2 vacc...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.02294-10

    authors: Beach NM,Smith SM,Ramamoorthy S,Meng XJ

    更新日期:2011-05-01 00:00:00

  • Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency.

    abstract::Like other herpesviruses, Kaposi's sarcoma-associated herpesvirus (KSHV, also designated human herpesvirus 8) can establish a latent infection in the infected host. During latency a small number of genes are expressed. One of those genes encodes latency-associated nuclear antigen (LANA), which is constitutively expres...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.78.12.6585-6594.2004

    authors: Lan K,Kuppers DA,Verma SC,Robertson ES

    更新日期:2004-06-01 00:00:00

  • Some physiochemical properties of Yaba poxvirus deoxyribonucleic acid.

    abstract::Yaba tumor poxvirus deoxyribonucleic acid (DNA) has a density of 1.6905 in CsCl and its T(m) value in 0.015 m citrate in saline is 82.3. The guanine plus cytosine content estimated from these properties was taken to be 32.5 +/- 0.5%, a value 2 to 3% less than for DNA from other poxviruses reported to date. ...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.3.2.114-118.1969

    authors: Yohn DS,Gallagher JF

    更新日期:1969-02-01 00:00:00

  • The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes.

    abstract::Baculoviruses, although they infect insects in nature, can transduce a wide variety of mammalian cells and are therefore promising gene therapy vectors. However, baculovirus transduction into many mammalian cells is very inefficient, and the limiting stages and factors remain unknown. An important finding is that a sh...

    journal_title:Journal of virology

    pub_type: 杂志文章

    doi:10.1128/JVI.00709-19

    authors: Hu L,Li Y,Ning YJ,Deng F,Vlak JM,Hu Z,Wang H,Wang M

    更新日期:2019-07-17 00:00:00