当前位置： SCI文献检索 > SAUDI JOURNAL OF BIOLOGICAL SCIENCES期刊下所有文献 > Diazepam ameliorates altered proinflammatory and cardiac markers in stress exposed rats.

Diazepam ameliorates altered proinflammatory and cardiac markers in stress exposed rats.

Abstract：

:Regular exposure to stress causes alteration in biochemical parameter but till date no specific medicine prescribed for controlling it. Current study aimed to determine the effect of Diazepam on proinflammatory and cardiac markers in stress exposed rats. Male Wistar rats were divided into four groups with six animals in each group for 90 days study. Group-1 served as a Normal Control (NC), Groups-2, as a Disease Control (DC), Group-3 as a Diazepam Control (DMC) and Group-4 as a Disease + Diazepam Treatment (DT). DMC and DT animals exposed to regular stress by forced swimming exercise method for 90 days. DMC and DT received 5 mg/kg, p.o the daily dose of Diazepam. At the end of the protocol, animals were sacrificed. The level of serum proinflammatory marker interleukin-6 in DC increased significantly (p < 0.001) while restored significantly (p < 0.001) in DT. Level of interleukin-10 in DC decreased significantly (p < 0.001) while restored significantly (p < 0.001) in DT. Level of fibrinogen was also increased by stress, which was restored significantly (p < 0.05) by diazepam. Increased level of Creatine kinase-MB (CK-MB) by stress was restored significantly (p < 0.05) by diazepam. The level of cortisol was increased also significantly (p < 0.001) and restored to normal by diazepam. The level of C-reactive protein (CRP) and cholesterol was increased significantly (p < 0.01; p < 0.001) by stress while restored significantly (p < 0.01; p < 0.001) by diazepam. Findings from results suggest that diazepam ameliorates altered proinflammatory and cardiac markers in stress exposed rats.

journal_name

Saudi J Biol Sci

journal_title

Saudi journal of biological sciences

authors

Al-Abbasi FA

doi

10.1016/j.sjbs.2020.10.042

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

566-571

issue

1

eissn

1319-562X

issn

2213-7106

pii

S1319-562X(20)30528-3

journal_volume

28

pub_type

杂志文章

相关文献

SAUDI JOURNAL OF BIOLOGICAL SCIENCES文献大全
  • Diversity of purple nonsulfur bacteria in shrimp ponds with varying mercury levels.

    abstract：:This research aimed to study the diversity of purple nonsulfur bacteria (PNSB) and to investigate the effect of Hg concentrations in shrimp ponds on PNSB diversity. Amplification of the pufM gene was detected in 13 and 10 samples of water and sediment collected from 16 shrimp ponds in Southern Thailand. In addition to...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.05.014

    authors： Mukkata K,Kantachote D,Wittayaweerasak B,Techkarnjanaruk S,Boonapatcharoen N

    更新日期：2016-07-01 00:00:00

  • Environmentally induced nephrotoxicity and histopathological alternations in Wallago attu and Cirrhinus mrigla.

    abstract：:Fish kidneys are sensitive to chemical changes in the freshwater ecosystem because they are directly and constantly exposed to chemicals dissolved in the water. This study evaluated nephrotoxicity in Wallago attu and Cirrhinus mrigala harvested from the Chenab River in an area of industrial and sewage waste disposal. ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2019.02.003

    authors： Hussain B,Fatima M,Al-Ghanim KA,Mahboob S

    更新日期：2019-05-01 00:00:00

  • Extraction and characterization of gelatin from camel skin (potential halal gelatin) and production of gelatin nanoparticles.

    abstract：:Gelatin is used as an ingredient in both food and non-food industries as a gelling agent, stabilizer, thickener, emulsifier, and film former. Porcine skins, bovine hides, and cattle bones are the most common sources of gelatin. However, mammalian gelatins are rejected by some consumers due to social, cultural, religio...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.03.022

    authors： Ahmed MA,Al-Kahtani HA,Jaswir I,AbuTarboush H,Ismail EA

    更新日期：2020-06-01 00:00:00

  • Genetic analysis of the 2019 coronavirus pandemic with from real-time reverse transcriptase polymerase chain reaction.

    abstract：:Corona viruses (CoV) are known to cause extreme pandemics in the globe. The year 2020 will be a pandemic with the spread of the novel coronavirus (SARS-CoV-2) across the globe. Coronavirus 2019 (COVID-19) has been a part of our scary life for more than a quarter of a year in 2020. The Wuhan market and China have been ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2020.11.035

    authors： Farasani A

    更新日期：2021-01-01 00:00:00

  • Overexpression of BAS1 in rice blast fungus can promote blast fungus growth, sporulation and virulence in planta.

    abstract：:Background: BAS1 is biotrophy-associated secreted protein of rice blast strain (Magnaporthe oryzae). In order to study the effect of BAS1 on virulence of rice blast strain, we characterized function of BAS1 using a purified prokaryotic expression product of BAS1 and its overexpression strain. Results: Our results show...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2017.11.032

    authors： Yang J,Liu L,Wang Y,Wang C,Yan J,Liu Y,Wang C,Li C

    更新日期：2017-12-01 00:00:00

  • Interference of phosphane copper (I) complexes of β-carboline with quorum sensing regulated virulence functions and biofilm in foodborne pathogenic bacteria: A first report.

    abstract：:Foodborne pathogens are one of the major cause of food-related diseases and food poisoning. Bacterial biofilms and quorum sensing (QS) mechanism of cell-cell communication have also been found to be associated with several outbreaks of foodborne diseases and are great threat to food safety. Therefore, In the present s...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.04.013

    authors： Al-Shabib NA,Husain FM,Khan RA,Khan MS,Alam MZ,Ansari FA,Laeeq S,Zubair M,Shahzad SA,Khan JM,Alsalme A,Ahmad I

    更新日期：2019-02-01 00:00:00

  • Effects of α lipoic acid on noise induced oxidative stress in rats.

    abstract：:This study was conducted to identify how exposure to ambient noise that is over 75 dB affects the oxidant-antioxidant profile using hematological and biochemical indicators, and to investigate the effects of a strong and current antioxidant, α lipoic acid, on rats that wer...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.08.008

    authors： Karafakioğlu YS

    更新日期：2019-07-01 00:00:00

  • Bioaccumulation of lead nitrate in tissues and its effects on hematological and biochemical parameters of Clarias gariepinus.

    abstract：:Clarias gariepinus, weighing 119.18 ± 5.21 g, were exposed to 0%, 20%, 40%, and 60% of the LC50 lead nitrate, Pb(NO3)2, which represents the following treatments 0 (control), 16, 32, and 48 mg/l, respectively, for a period of 10 and 20 days. The results showed that the bioaccumulation of Pb(NO3)2 in gills were signifi...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.01.015

    authors： Abdel-Warith AA,Younis EMI,Al-Asgah NA,Rady AM,Allam HY

    更新日期：2020-03-01 00:00:00

  • Bioanthropological analysis of human occipital condyles using geometric morphometric method.

    abstract：:Sex differences are present in all parts of the body, including the skeletal system. Several methods are used to analyze the sex differences of skeleton, while more recently, a new method called geometric morphometry has been used. The aim of this study was to examine the sexual dimorphism of occipital condyles on hum...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.09.019

    authors： Aida SH,Zurifa A,Ilvana H,Senad Š,Maida RT,Izeta A,Kapo Sanita M,Rifat H

    更新日期：2020-12-01 00:00:00

  • Relationship between expression of CXCR7 and NF-κB in breast cancer tissue and occurrence of breast cancer and lymphatic metastasis.

    abstract：:It is designed to discuss the relationship between the expression of chemokine receptor 7 (chemokine receptor 7, CXCR7) and nuclear transcription factor-κB (nuclear factor kappa B, NF-κB) and the occurrence of the breast cancer and lymphatic metastasis. METHOD:80 samples were excised and confirmed as breast cancer th...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2017.11.009

    authors： Yuan CL,Liu ZH,Zou N,Wang YL,Chen ZY

    更新日期：2017-12-01 00:00:00

  • Inhibition of autophagy of Cajal mesenchymal cells by gavage of tong bian decoction based on the rat model of chronic transit constipation.

    abstract：:The objective of this research was to study the effect of tong bian decoction on colon transport function of interstitial cells of Cajal (ICC) in chronic transit constipation (CTC) and the inhibition of autophagy of ICC, so as to achieve the free movement of the bowels. In this research, the experimental rats were div...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2019.11.040

    authors： Zhou X,Qian H,Zhang D,Zeng L

    更新日期：2020-02-01 00:00:00

  • D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway.

    abstract：:Cancer is still remain as a global burden with the 18.1 million and 9.6 million new cases and mortlities, respectively estimated globally. Leukemia may arise at all ages varied from the infants to elders. In this exploration, we planned to evaluate the antiproliferative effect of D-pinitol on human leukemia MOLT-4 cel...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.06.034

    authors： Yao X,Shi K,Yang Y,Gu X,Tan W,Wang Q,Gao X,Priya Veeraraghavan V,Mohan SK,Jin S

    更新日期：2020-08-01 00:00:00

  • The expression of macrophage migration inhibitory factor in the non-small cell lung cancer.

    abstract：Objective:The objective was to investigate the expression of macrophage migration inhibitory factor (MIF) in non-small cell lung cancer (NSCLC), as well as the effects of macrophage MIF on tumor cells. Methods:The human NSCLC cell strains H358 and H524 were selected as research objects. The Real-Time Polymerase Chain ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.04.027

    authors： Zhang H,Duan J,Wu O

    更新日期：2020-06-01 00:00:00

  • Genetic diversity of begomoviruses infecting tomato plant in Saudi Arabia.

    abstract：:Tomato is known as a highly valuable crop and grown worldwide for various uses. The cultivation and tomato production severely affected globally by several diseases caused by various pathogens. Begomoviruses causes yellow mosaic and leaf curl disease of tomato in the tropical, subtropical, temperate, and semi-arid reg...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2019.08.015

    authors： Sohrab SS

    更新日期：2020-01-01 00:00:00

  • Nutritional and technological assessment of durum wheat-faba bean enriched flours, and sensory quality of developed composite bread.

    abstract：:Faba beans are acknowledged as a good source of proteins, minerals, fibers, vitamins and antioxidants. A blending study was undertaken in order to prepare naturally bread from enriched flours with added nutritional value, mainly in terms of Iron and proteins. Enriched flours were prepared with varied levels (25, 30, 3...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.10.053

    authors： Benayad A,Taghouti M,Benali A,Aboussaleh Y,Benbrahim N

    更新日期：2021-01-01 00:00:00

  • Green synthesis and characterization of Carica papaya leaf extract coated silver nanoparticles through X-ray diffraction, electron microscopy and evaluation of bactericidal properties.

    abstract：:The evolution of nanotechnology and the production of nanomedicine from various sources had proven to be of intense value in the field of biomedicine. The smaller size of nanoparticles is gaining importance in research for the treatment of various diseases. Moreover the production of nanoparticles is eco-friendly and ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.01.007

    authors： Banala RR,Nagati VB,Karnati PR

    更新日期：2015-09-01 00:00:00

  • Synthesis of silver nanoparticles using Sacha inchi (Plukenetia volubilis L.) leaf extracts.

    abstract：:Silver nanoparticles (AgNPs) are fabricated using Sacha inchi (SI) or (Plukenetia volubilis L.) leaf extract as non-toxic reducing agent with particle size ranging from 4 to 25 nm. Optical, structural and morphological properties of the synthesized nanoparticles have been characterized by using Visual, UV-Vis spectrop...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2014.07.004

    authors： Kumar B,Smita K,Cumbal L,Debut A

    更新日期：2014-12-01 00:00:00

  • Enhancement of yield, nutritional and nutraceutical properties of two common bean cultivars following the application of seaweed extract (Ecklonia maxima).

    abstract：:In the present study, application of Ecklonia maxima extract (Kelpak SL - a water soluble concentrate) was optimized and its impact on yield, nutraceutical and nutritional potential of Phaseolus vulgaris L. (var. Aura and Toska) was measured. The study was carried out in 2012 and 2013 in Poland. During the growing sea...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.01.039

    authors： Kocira A,Świeca M,Kocira S,Złotek U,Jakubczyk A

    更新日期：2018-03-01 00:00:00

  • Digestibility of phosphorous in cereals and co-products for animal feed.

    abstract：:Feed ingredients used in swine diets contain various levels and availabilities of nutrients. Nutritional precision evaluation of each ingredient is necessary for formulating diets of pigs. Especially, phosphorous (P) is one of important nutrients for metabolism. However, current data of P digestibility were most appar...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.12.003

    authors： Park S,Cho E,Chung H,Cho K,Sa S,Balasubramanian B,Choi T,Jeong Y

    更新日期：2019-02-01 00:00:00

  • 1H HRMAS-NMR based metabolic fingerprints for discrimination of cheeses based on sensory qualities.

    abstract：:In this study, the 1H HRMAS-NMR (High-resolution Magic Angle Spinning-Nuclear Magnetic Resonance) spectra of 52 cheese samples obtained from the South Korean dairy farms were evaluated for their metabolic profiling and intensities associating with the sensory qualities. The NMR profiles displayed a broad range of comp...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.04.043

    authors： Kandasamy S,Yoo J,Yun J,Kang HB,Seol KH,Ham JS

    更新日期：2020-06-01 00:00:00

  • Ecology, distribution mapping and conservation implications of four critically endangered endemic plants of Kashmir Himalaya.

    abstract：:During the last few decades, human-driven activities have led to indiscriminate habitat destruction and exploitation of many plant species in Kashmir Himalaya. As a result, many species have become threatened and are struggling for survival. Of particular concern are the endemic and critically endangered species which...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.05.006

    authors： Hussain Mir A,Tyub S,Kamili AN

    更新日期：2020-09-01 00:00:00

  • Antiulcerogenic activity of the hydroalcoholic extract of leaves of Annona muricata Linnaeus in mice.

    abstract：:Annona muricata Linnaeus, popularly known as "graviola" and also called soursop, is a species typical of countries with a tropical climate, and it is used in folk medicine as an anticancer, analgesic and antispasmodic agent. The aim of the present study was to validate the gastroprotective activity of the hydroalcohol...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.01.024

    authors： Bento EB,Júnior FEB,de Oliveira DR,Fernandes CN,de Araújo Delmondes G,Cesário FRAS,Rodrigues CKS,Sales VDS,de Figueiredo FRSDN,Lemos ICS,Monteiro ÁB,de Menezes IRA,da Costa JGM,Kerntopf MR

    更新日期：2018-05-01 00:00:00

  • Effects of soybean oligosaccharides on intestinal microbial communities and immune modulation in mice.

    abstract：:Soybean oligosaccharides (SBOSs) are potential prebiotics that may be used to improve immune function. Here, we investigated the effects of intragastric administration of SBOSs in mice to determine the effects on autochthonous intestinal microbial communities and immunological parameters. Results E: After 22-day admin...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.09.004

    authors： Ma Y,Wu X,Giovanni V,Meng X

    更新日期：2017-01-01 00:00:00

  • Ultrastructural differentiation of sperm tail region in Diplometopon zarudnyi (an amphisbaenian reptile).

    abstract：:Diplometopon zarudnyi, a worm lizard belongs to amphisbaenia under trogonophidae family. This species exists in limited areas of the Arabian Peninsula and is an oscillating digger found in sub-surface soils. The present study aimed to investigate the sperm tail differentiation in D. zarudnyi. Ten male adults of D. zar...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.05.002

    authors： Al-Dokhi O,Mukhtar A,Al-Dosary A,Al-Sadoon MK

    更新日期：2015-07-01 00:00:00

  • Screening and identification of novel isolate Streptomyces sp., NLKPB45 from Nellore costal region for its biomedical applications.

    abstract：:Actinobacteria, which are the prolific producers of antibiotics and significant suppliers to the pharmaceutical industry, can produce a wide variety of bioactive metabolites. An actinomycete strain designated NLKPB45 was isolated from mangrove soils samples of Nellore coastal regions Andhra Pradesh and assessed for an...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.08.027

    authors： Kalyani BS,Krishna PS,Sreenivasulu K

    更新日期：2019-11-01 00:00:00

  • Anti-biofilm activity of LC-MS based Solanum nigrum essential oils against multi drug resistant biofilm forming P. mirabilis.

    abstract：:Urinary tract infections are second most important diseases worldwide due to the increased amount of antibiotic resistant microbes. Among the Gram negative bacteria, P. mirabilis is the dominant biofilm producer in urinary tract infections next to E. coli. Biofilm is a process that produced self-matrix of more virulen...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.10.003

    authors： Khaled JM,Alyahya SA,Chenthis Kanisha C,Alharbi NS,Kadaikunnan S,Ramachandran G,Alanzi KF,Rajivgandhi G,Vimala R,Manoharan N

    更新日期：2021-01-01 00:00:00

  • Phytochemical and taxonomic evaluation of Rhazya stricta in Saudi Arabia.

    abstract：:Rhazya stricta Decne is an important medicinal species used in indigenous medicinal herbal drugs to cure various diseases in South Asia (Pakistan, India and Afghanistan) and in the Middle East (e.g. Saudi Arabia, Qatar, United Arab Emirates (UAE), Iran and Iraq). Some of its alkaloids have been reported to have antica...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.10.017

    authors： Bukhari NA,Al-Otaibi RA,Ibhrahim MM

    更新日期：2017-11-01 00:00:00

  • Reduction of post-prandial hyperglycemia by mulberry tea in type-2 diabetes patients.

    abstract：AIM:The dietary contents have a very important role in the management of metabolic syndrome along with type 2 diabetes mellitus (T2DM). Indian diet contains a large amount of carbohydrates that set off unpredictable blood sugar fluctuations and leads to increased risk of diabetic complications. The aim of the present s...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2014.04.005

    authors： Banu S,Jabir NR,Manjunath NC,Khan MS,Ashraf GM,Kamal MA,Tabrez S

    更新日期：2015-01-01 00:00:00

  • In vitro biocontrol activity of halotolerant Streptomyces aureofaciens K20: A potent antagonist against Macrophomina phaseolina (Tassi) Goid.

    abstract：:A halotolerant actinobacterial strain isolated from salinity affected soil of Eastern Indo-Gangetic plains (IGP), Uttar Pradesh, India, was characterised for its antagonistic potential against Macrophomina phaseolina by dual-culture assay. It was shown to effectively inhibit the growth of M. phaseolina with an inhibit...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.12.004

    authors： Shrivastava P,Kumar R,Yandigeri MS

    更新日期：2017-01-01 00:00:00

  • Effect of environmental factors on the yield of selected mushroom species growing in two different agro ecological zones of Pakistan.

    abstract：:Mushrooms are a rich source of protein and vitamins as human food. In view of the growing importance of mushroom in Pakistan, a research study was initiated with the objective to examine the suitability of Oyster mushroom cultivation and to compare the growth and yield of Oyster mushroom in two different areas (Peshaw...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2010.06.004

    authors： Sher H,Al-Yemeni M,Bahkali AHA,Sher H

    更新日期：2010-10-01 00:00:00