Measurement of the hyperelastic properties of 44 pathological ex vivo breast tissue samples.

abstract：:The low energy model of the GEANT4 Monte Carlo toolkit was used to simulate the energy response of a T.P.A. Mk-II ionization chamber under a variety of different conditions. The sample position resulting in the maximum response along the axial direction of the chamber was obtained. The parameters of the simulation wer...

journal_title：Physics in medicine and biology

authors： Seneviratne MD,Reinhard MI,Baldock C

更新日期：2007-07-07 00:00:00

abstract：:Recent studies have demonstrated the feasibility of transcranial high-intensity focused ultrasound (HIFU) therapy in the brain using adaptive focusing techniques. However, the complexity of the procedures imposes provision of accurate targeting, monitoring and control of this emerging therapeutic modality in order to ...

journal_title：Physics in medicine and biology

authors： Larrat B,Pernot M,Aubry JF,Dervishi E,Sinkus R,Seilhean D,Marie Y,Boch AL,Fink M,Tanter M

更新日期：2010-01-21 00:00:00

abstract：:As the use of radiofrequency (RF) electromagnetic (EM) fields has increased along with increased use of wireless communication, the possible related health risks have also been widely discussed. One safety aspect is the interaction of medical implants and RF devices like mobile phones. In the literature, effects on ac...

journal_title：Physics in medicine and biology

authors： Virtanen H,Keshvari J,Lappalainen R

更新日期：2007-03-07 00:00:00

abstract：:This work aims to develop, implement and validate a Monte Carlo (MC)-based independent dose calculation (IDC) framework to perform patient-specific quality assurance (QA) for multi-leaf collimator (MLC)-based CyberKnife® (Accuray Inc., Sunnyvale, CA) treatment plans. The IDC framework uses an XML-format treatment plan...

journal_title：Physics in medicine and biology

authors： Mackeprang PH,Vuong D,Volken W,Henzen D,Schmidhalter D,Malthaner M,Mueller S,Frei D,Stampanoni MFM,Dal Pra A,Aebersold DM,Fix MK,Manser P

更新日期：2017-12-19 00:00:00

abstract：:We describe a radiation therapy treatment plan optimization method that explicitly considers the effects of interfraction organ motion through optimization on the clinical target volume (CTV), and investigate how it compares to conventional planning using a planning target volume (PTV). The method uses simulated treat...

journal_title：Physics in medicine and biology

authors： Fredriksson A,Engwall E,Andersson B

更新日期：2020-12-21 00:00:00

abstract：:Several methods of flip angle mapping for magnetic resonance imaging have been proposed. We evaluated the accuracy of five methods of flip angle measurement in the presence of measurement noise. Our analysis was performed in a closed form by propagation of probability density functions (PDFs). The flip angle mapping m...

journal_title：Physics in medicine and biology

authors： Morrell GR,Schabel MC

更新日期：2010-10-21 00:00:00

abstract：:Few quantitative data are available on the kinetics of polymerization reactions in polymer gel (PAG) dosimeters and their long-term stability. Post-irradiation polymerization reactions have been found to continue for several weeks, posing questions regarding dosimeter stability and its achievement. In this paper we re...

journal_title：Physics in medicine and biology

authors： McJury M,Oldham M,Leach MO,Webb S

更新日期：1999-08-01 00:00:00

abstract：:The variety of treatment options for cancer patients has increased significantly in recent years. Not only do we combine radiation with surgery and chemotherapy, new therapeutic approaches such as immunotherapy and targeted therapies are starting to play a bigger role. Physics has made significant contributions to rad...

journal_title：Physics in medicine and biology

authors： Grassberger C,Paganetti H

更新日期：2016-11-07 00:00:00

abstract：:A recent paper proposed a novel technique for determining the total body water (TBW) of patients suffering with abnormal hydration levels, using a resonant cavity perturbation method. Current techniques to measure TBW are limited by resolution and technical constraints. However, this new method involves measuring the ...

journal_title：Physics in medicine and biology

authors： Stone DA,Robinson MP

更新日期：2004-05-07 00:00:00

abstract：:In recent years, optical techniques based on diffusion approximation have demonstrated their ability to gain rich spectral information about bone. However, these methods normally assume homogeneity, while cancellous bone and marrow form a highly heterogeneous two-phase medium. This paper studies the limitations of thi...

journal_title：Physics in medicine and biology

authors： Margallo-Balbás E,Taroni P,Pifferi A,Koolstra JH,v Ruijven LJ,French PJ

更新日期：2010-09-07 00:00:00

abstract：:Amorphous silicon (aSi:H) flat panel detectors are prevalent in radiotherapy for megavoltage imaging tasks. Any clinical and dosimetrical application requires a well-defined dose response of the system to achieve meaningful results. Due to radiation damages, panels deteriorate and the linearity of pixel response to do...

journal_title：Physics in medicine and biology

authors： Huber S,Mooslechner M,Mitterlechner B,Weichenberger H,Serpa M,Sedlmayer F,Deutschmann H

更新日期：2013-09-21 00:00:00

abstract：:State of the art point-spread function (PSF) corrections implemented in positron emission tomography/computed tomography (PET/CT) reconstruction improved image quality and diagnostic performance but caused an increase in the standardized uptake value (SUV) compared to a conventional OSEM reconstruction system. The EAN...

journal_title：Physics in medicine and biology

authors： Ferretti A,Chondrogiannis S,Rampin L,Bellan E,Marzola MC,Grassetto G,Gusella S,Maffione AM,Gava M,Rubello D

更新日期：2018-11-26 00:00:00

abstract：:Inverse planning techniques are known to produce intensity-modulated beams (IMBs) that are highly modulated. They are characterized by the fact that they contain high-frequency modulations that are absent in the profiles that are easier to deliver. For the purpose of this study these clinically unwanted fluctuations a...

journal_title：Physics in medicine and biology

authors： Coolens C,Evans PM,Seco J,Webb S

更新日期：2004-09-07 00:00:00

abstract：:The function of the placenta is challenging to characterize and as a result is understudied, despite the growing awareness of the impact of the placental environment on human health and development. Medical imaging has the potential to improve our ability to screen for diseases associated with placental insufficiency,...

journal_title：Physics in medicine and biology

authors： Wu C,Bayer CL

更新日期：2018-07-09 00:00:00

abstract：:The classical Sievert integral method is a valuable tool for dose rate calculations around brachytherapy sources, combining simplicity with reasonable computational times. However, its accuracy in predicting dose rate anisotropy around 192Ir brachytherapy sources has been repeatedly put into question. In this work, we...

journal_title：Physics in medicine and biology

authors： Karaiskos P,Angelopoulos A,Baras P,Rozaki-Mavrouli H,Sandilos P,Vlachos L,Sakelliou L

更新日期：2000-02-01 00:00:00

abstract：:For patients with partial epilepsy, automatic spike detection techniques applied to interictal MEG data often discover several potentially epileptogenic brain regions. An important determination in treatment planning is which of these detected regions are most likely to be the primary sources of epileptogenic activity...

journal_title：Physics in medicine and biology

authors： Ossadtchi A,Mosher JC,Sutherling WW,Greenblatt RE,Leahy RM

更新日期：2005-07-21 00:00:00

abstract：:Radiotherapy and particle therapy treatment planning require accurate knowledge of the electron density and elemental composition of the tissues in the beam path to predict the local dose deposition. We describe a method for the analysis of dual energy computed tomography (DECT) images that provides the electron densi...

journal_title：Physics in medicine and biology

authors： van Abbema JK,van Goethem MJ,Greuter MJ,van der Schaaf A,Brandenburg S,van der Graaf ER

更新日期：2015-05-07 00:00:00

abstract：:This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-...

journal_title：Physics in medicine and biology

authors： Huang Q,Xu J,Tsui BM,Gullberg GT

更新日期：2009-07-07 00:00:00

abstract：:Exploiting the field response of magnetic tracers, magnetic particle imaging (MPI) allows direct, local quantification of the tracer concentration in bulk structures. Here, we investigated the use of characteristic field response functions to spatially resolve the absolute concentration of multiple nanoparticle specie...

journal_title：Physics in medicine and biology

authors： Han SH,Cho E,Lee DK,Cho G,Kim YR,Cho H

更新日期：2014-11-07 00:00:00

abstract：:The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and w...

journal_title：Physics in medicine and biology

authors： Craft D,Halabi T,Bortfeld T

更新日期：2005-12-21 00:00:00

abstract：:Therapy with helium ions is currently receiving significantly increasing interest because helium ions have a sharper penumbra than protons and undergo less fragmentation than carbon ions and thus require less complicated dose calculations. For any ion of interest in hadron therapy, the accuracy of dose delivery is lim...

journal_title：Physics in medicine and biology

authors： Ozoemelam I,van der Graaf E,Brandenburg S,Dendooven P

更新日期：2019-12-05 00:00:00

abstract：:As an x-ray beam goes through the human body, it will collect important information via interaction with tissues. Since this interaction is energy-sensitive, the state-of-the-art spectral CT technologies provide higher quality images of biological tissues with x-ray energy information (or spectral information). With e...

journal_title：Physics in medicine and biology

authors： Shi Z,Yang H,Cong W,Wang G

更新日期：2016-06-07 00:00:00

abstract：:This work investigates the attenuation of a proton beam to reconstruct the map of the linear attenuation coefficient of a material which is mainly caused by the inelastic interactions of protons with matter. Attenuation proton computed tomography (pCT) suffers from a poor spatial resolution due to multiple Coulomb sca...

journal_title：Physics in medicine and biology

authors： Quiñones CT,Létang JM,Rit S

更新日期：2016-05-07 00:00:00

abstract：:A Monte Carlo computational model of a fluoroscopic imaging chain was used for deriving optimal technique factors for paediatric fluoroscopy. The optimal technique was defined as the one that minimizes the absorbed dose (or dose rate) in the patient with a constraint of constant image quality. Image quality was assess...

journal_title：Physics in medicine and biology

authors： Tapiovaara MJ,Sandborg M,Dance DR

更新日期：1999-02-01 00:00:00

abstract：:In order to optimize external-beam conformal radiotherapy, patient movement during treatment must be minimized. For treatment on the upper torso, the target organs are known to move substantially due to patient respiration. This paper deals with the technical aspects of gating the radiotherapy beam synchronously with ...

journal_title：Physics in medicine and biology

authors： Kubo HD,Hill BC

更新日期：1996-01-01 00:00:00

abstract：:A mathematical transcription of the intrinsic circuit of the CA1 region of the rat dorsal hippocampus was made and the model parameters adjusted according to experimental data from intracellular recordings and single channel kinetics. This model was able to simulate well the profile of the field potentials recorded ex...

journal_title：Physics in medicine and biology

authors： Almeida AC,Fernandes de Lima VM,Infantosi AF

更新日期：1998-09-01 00:00:00

abstract：:Following the publication of ICRU Report 50, the concepts of GTV (gross tumour volume). CTV (clinical target volume) and PTV (planning target volume) are being used in radiotherapy planning with increasing frequency. In 3D planning, the GTV (or CTV) is normally outlined by the clinician in CT or MRI slices. The PTV is...

journal_title：Physics in medicine and biology

authors： Stroom JC,Storchi PR

更新日期：1997-04-01 00:00:00

abstract：:This study evaluates the dosimetric performance of the polymer gel dosimeter 'Methacrylic and Ascorbic acid in Gelatin, initiated by Copper' and its suitability for quality assurance and analysis of I-131-targeted radionuclide therapy dosimetry. Four batches of gel were manufactured in-house and sets of calibration vi...

journal_title：Physics in medicine and biology

authors： Gear JI,Charles-Edwards E,Partridge M,Flux GD

更新日期：2011-11-21 00:00:00

abstract：:Respiratory gating can reduce the apparent respiratory motion during imaging and treatment; however, residual motion within the gating window remains. Respiratory training can improve respiratory reproducibility and, therefore, the efficacy of respiratory-gated radiotherapy. This study was conducted to determine wheth...

journal_title：Physics in medicine and biology

authors： George R,Ramakrishnan V,Siebers JV,Chung TD,Keall PJ

更新日期：2006-10-21 00:00:00

abstract：:Numerical computations are used to evaluate electric field dosimetry for high-resolution anatomically based inhomogeneous models of a human male child, and male and female rats and mice, under exposure to 60 Hz uniform magnetic field sources of three perpendicular orientations. The goal is to compare the child data to...

journal_title：Physics in medicine and biology

authors： Dawson TW,Caputa K,Stuchly MA

更新日期：2002-07-21 00:00:00