Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR: quinolinone alkaloids of Haplophyllum acutifolium.

abstract：:Plants belonging to the genus Leonurus, also named motherwort, are traditionally used for anti-gynecological disorder in East Asia, and for sedative in Europe. Chemical investigation of the genus Leonurus not only enriched the natural products library, but also enlarged the pharmacological application of this traditio...

journal_title：Phytochemistry

authors： Zhang RH,Liu ZK,Yang DS,Zhang XJ,Sun HD,Xiao WL

更新日期：2018-03-01 00:00:00

abstract：:In addition to lotaustralin and linamarin, a novel cyanogenic glycoside, 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)-2-met hylbutanenitrile , two novel non-cyanogenic glycosides, (2S)-((6-O-(beta-D-apiofuranosyl)-beta-D- glucopyranosyl)oxy)butane and 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)o...

journal_title：Phytochemistry

authors： Prawat H,Mahidol C,Ruchirawat S,Prawat U,Tuntiwachwut-tikul P,Tooptakong U,Taylor WC,Pakawatchai C,Skeleton BW,White AH

更新日期：1995-11-01 00:00:00

abstract：:Investigation of a hairy root culture of Tripterygium wilfordii var. regelii transformed with Agrobacterium rhizogenes resulted in the isolation of new diterpenoid and sesquiterpenoid together with known triterpenoids. These structures were determined by spectroscopic analyses. ...

journal_title：Phytochemistry

authors： Nakano K,Yoshida C,Furukawa W,Takaishi Y,Shishido K

更新日期：1998-11-20 00:00:00

abstract：:The profiles of non-volatile oxylipins of pea (Pisum sativum) seedlings were examined by gas chromatography-mass spectrometry after invitro incubation with α-linolenic acid. The 13-lipoxygenase/hydroperoxide lyase (HPL) products were predominant in the leaves, while the roots possess both 13- and 9-HPL products. Allen...

journal_title：Phytochemistry

authors： Mukhtarova LS,Mukhitova FK,Gogolev YV,Grechkin AN

更新日期：2011-04-01 00:00:00

abstract：:Seven dammarane glycosides, gypenosides GC1 to GC7, together with ten known compounds, gypenosides V, XIV, XLII-XLVI, gynosaponins TN-1, -2, and gymnemaside VI, were isolated from the methanol extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated by both analysis of 1D and 2D NMR spe...

journal_title：Phytochemistry

authors： Kim JH,Han YN

更新日期：2011-08-01 00:00:00

abstract：:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was eva...

journal_title：Phytochemistry

authors： Takano I,Yasuda I,Nishijima M,Yanagi Y,Takeya K,Itokawa H

更新日期：1997-02-01 00:00:00

abstract：:Poliumoside, forsythoside B, echinacoside and arenarioside, caffeic glycoside esters, were isolated from several species of Oleaceae. The poliumoside/forsythoside ratio distinguishes Jasminum nudiflorum from J. mesnyi. Arenarioside and forsythoside B act in Forsythia species as good hybridization markers. ...

journal_title：Phytochemistry

authors： Andary C,Tahrouch S,Marion C,Wylde R,Heitz A

更新日期：1992-03-01 00:00:00

abstract：:A truncated history of the contribution of plants to medicine is given with reference to some of the less well known ancestors of the Harborne family. Six of the top 20 prescriptions dispensed in 1996 were natural products and the clinical use of drugs such as artemisinin, etoposide and taxol has once more focussed at...

journal_title：Phytochemistry

authors： Phillipson JD

更新日期：2001-02-01 00:00:00

abstract：:Acylation is a prevalent chemical modification that to a significant extent accounts for the tremendous diversity of plant metabolites. To catalyze acyl transfer reactions, higher plants have evolved acyltransferases that accept beta-acetal esters, typically 1-O-glucose esters, as an alternative to the ubiquitously oc...

journal_title：Phytochemistry

authors： Stehle F,Brandt W,Stubbs MT,Milkowski C,Strack D

更新日期：2009-10-01 00:00:00

abstract：:An approach, using well characterized procedures, is presented that should be of general applicability for the structural elucidation of complex sugar moieties of natural products. The methods used are exemplified by the structure elucidation of a new gitogenin-based steroidal saponin that has a strong leishmanicidal ...

journal_title：Phytochemistry

authors： Plock A,Beyer G,Hiller K,Gründemann E,Krause E,Nimtz M,Wray V

更新日期：2001-06-01 00:00:00

abstract：:A new triterpenoid saponin, 3-O-[beta-D-glucopyranosyl(1----4)-beta-D- xylopyranosyl]-28-O-beta-D-glucopyranosyl-30-methyloleanate-9(11), 12-dien- 2,3,23-trihydroxyl-28-oic acid, was isolated from the roots of Phytolacca esculenta. The structure was assigned by chemical methods and spectral analysis (1H, 13C, DEPT NMR...

journal_title：Phytochemistry

authors： Yi YH

更新日期：1992-07-01 00:00:00

abstract：:Ten stigmastane-type steroids bearing unusual Δ28-24-hydroxy side chains, dictyopterisins A-J, including three pairs of C-24 epimers, dictyopterisins B/C, F/G, and I/J, were isolated from the brown alga Dictyopteris undulata Holmes, together with two previously reported analogues, (24S)- and (24R)-saringosterol. Their...

journal_title：Phytochemistry

authors： Feng MT,Wang T,Liu AH,Li J,Yao LG,Wang B,Guo YW,Mao SC

更新日期：2018-02-01 00:00:00

abstract：:Two new oleanene glycosides (1-2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of alpha-L-arabinopyranose, alpha-L-rhamnopyranose and galacto...

journal_title：Phytochemistry

authors： Baykal T,Bedir E,Calis I,Aquino R,Piacente S,Pizza C

更新日期：1999-08-01 00:00:00

abstract：:Four new xanthones have been isolated from the roots of Hypericum roeperanum. Their structures have been established by a combination of spectroscopic and chemical methods as 1,6-dihydroxy-5-methoxy-4',5'-dihydro-4',4',5'-trimethylfurano- (2',3':3,4)-xanthone (5-O-methyl-2-deprenylrheediaxanthone B), 1,6-dihydroxy-5-m...

journal_title：Phytochemistry

authors： Rath G,Potterat O,Mavi S,Hostettmann K

更新日期：1996-09-01 00:00:00

abstract：:Three new phenylethanoid glycoside, named scrosides A-C and a new iridoid glycosides, named picroside IV, have been isolated from the underground parts of Picrorhiza scrophulariiflora, together with 11 known compounds. Their structures were elucidated by the means of 2D NMR spectroscopy and chemical methods. ...

journal_title：Phytochemistry

authors： Li JX,Li P,Tezuka Y,Namba T,Kadota S

更新日期：1998-06-01 00:00:00

abstract：:Five undescribed xanthones, 4-methoxypyranojacareubin, 4-hydroxy-3-prenylpyranoxanthone, 1-hydroxy-5,7-dimethoxyxanthone, 5-hydroxy-1,6,7-trimethoxyxanthone and 2-hydroxy-1,5-dimethoxyxanthone, together with thirty-three known xanthones were isolated from the roots of Mesua ferrea L. The structures of all isolated xan...

journal_title：Phytochemistry

authors： Chukaew A,Saithong S,Chusri S,Limsuwan S,Watanapokasin R,Voravuthikunchai SP,Chakthong S

更新日期：2019-01-01 00:00:00

abstract：:Ginseng occupies a prominent position in the list of best-selling natural products in the world. Compared to the long history of use and widespread research on Asian ginseng, the study of American ginseng is relatively limited. In the past decade, some promising advances have been achieved in understanding the chemist...

journal_title：Phytochemistry

authors： Qi LW,Wang CZ,Yuan CS

更新日期：2011-06-01 00:00:00

abstract：:A cyanogenic glycoside - 6'-O-galloylsambunigrin - has been isolated from the foliage of the Australian tropical rainforest tree species Elaeocarpus sericopetalus F. Muell. (Elaeocarpaceae). This is the first formal characterisation of a cyanogenic constituent in the Elaeocarpaceae family, and only the second in the o...

journal_title：Phytochemistry

authors： Miller RE,Stewart M,Capon RJ,Woodrow IE

更新日期：2006-07-01 00:00:00

abstract：:The antifungal glycoalkaloid alpha-tomatine of the tomato plant (Lycopersicon esculentum) is proposed to protect the plant against phytopathogenic fungi. Fusarium oxysporum f. sp. lycopersici, a vascular pathogen of tomato, produces a tomatinase enzyme which hydrolyses the glycoalkaloid into non-fungitoxic compounds. ...

journal_title：Phytochemistry

authors： Lairini K,Ruiz-Rubio M

更新日期：1997-08-01 00:00:00

abstract：:From the ethanolic extract of the aerial parts of Centaurea scoparia four new sesquiterpene lactones, belonging to the guaiane class, were isolated and identified, together with a known germacranolide. The structures were elucidated by spectroscopic methods including one- and two-dimensional NMR studies. The relative ...

journal_title：Phytochemistry

authors： Youssef DT

更新日期：1998-11-20 00:00:00

abstract：:The dichloromethane extract of the stem bark of Warburgia ugandensis afforded three new coloratane sesquiterpenes, namely: 6alpha,9alpha-dihydroxy-4(13),7-coloratadien-11,12-dial (1), 4(13),7-coloratadien-12,11-olide (2), and 7beta-hydroxy-4(13),8-coloratadien-11,12-olide (3), together with nine known sesquiterpenes, ...

journal_title：Phytochemistry

authors： Wube AA,Bucar F,Gibbons S,Asres K

更新日期：2005-10-01 00:00:00

abstract：:Examination of the bulbs of Bessera elegans (Liliaceae) led to isolation of nine new and five known steroidal glycosides. The structures of the nine compounds were determined based on the results of spectroscopic analysis, including two-dimensional NMR, and hydrolysis followed by chromatographic and spectroscopic anal...

journal_title：Phytochemistry

authors： Matsuo Y,Akagi N,Hashimoto C,Tachikawa F,Mimaki Y

更新日期：2013-12-01 00:00:00

abstract：:3β-Hydroxy-5β-cholestan-6-one was identified in the EtOAc extract of Ajuga hairy roots by micro-analysis using LC-MS/MS in the multiple reaction mode (MRM). Furthermore, administration of (2,2,4,4,7,7-(2)H6)- and (2,2,4,4,6,7,7-(2)H7)-cholesterols to the hairy roots followed by LC-MS/MS analysis of the EtOAc extract o...

journal_title：Phytochemistry

authors： Fujimoto Y,Maeda I,Ohyama K,Hikiba J,Kataoka H

更新日期：2015-03-01 00:00:00

abstract：:Aconitum carmichaelii has long been used as a traditional Chinese medicine, and its processed lateral roots are known commonly as fuzi. Aconitine-type C19-diterpenoid alkaloids accumulating in the lateral roots are some of the main toxicants of this species, yet their biosynthesis remains largely unresolved. As a firs...

journal_title：Phytochemistry

authors： Zhao D,Shen Y,Shi Y,Shi X,Qiao Q,Zi S,Zhao E,Yu D,Kennelly EJ

更新日期：2018-08-01 00:00:00

abstract：:During the past 50 years there have been tremendous advances in chemical and biological techniques of analysis that have transformed research in pharmacognosy. The PSE has regularly held symposia of relevance to pharmacognosy and some of these are briefly reviewed in the area of natural products from higher plants. Th...

journal_title：Phytochemistry

authors： Phillipson JD

更新日期：2007-11-01 00:00:00

abstract：:Profiles of terpenoid glycoside metabolites in glandular trichomes of Solanum habrochaites LA1777 leaves were generated using ultrahigh performance liquid chromatography/time-of-flight mass spectrometry with multiplexing of non-selective collision-induced dissociation (CID). Profiling data suggested a diverse group of...

journal_title：Phytochemistry

authors： Ekanayaka EA,Li C,Jones AD

更新日期：2014-02-01 00:00:00

abstract：:The Arabidopsis thaliana irregular xylem4 (irx4) cinnamoyl-CoA reductase 1 (CCR1) mutant was reassessed for its purported exclusive rate-limiting or key effects on lignification. Analyses of gross growth characteristics and stem cross-section anatomy, from seedling emergence to senescence, revealed that stunted irx4 m...

journal_title：Phytochemistry

authors： Patten AM,Cardenas CL,Cochrane FC,Laskar DD,Bedgar DL,Davin LB,Lewis NG

更新日期：2005-09-01 00:00:00

abstract：:Cytochrome P450-dependent monooxygenases (P450s) belonging to the CYP93E subfamily catalyze the C-24 oxidation of the triterpene backbone during the biosynthesis of triterpenoid saponins, which are bioactive plant natural products. In our attempts to produce plant triterpenoids in the yeast Saccharomyces cerevisiae, w...

journal_title：Phytochemistry

authors： Moses T,Thevelein JM,Goossens A,Pollier J

更新日期：2014-12-01 00:00:00

abstract：:Landraces of maize (Zea mays ssp. mays) and its wild teosinte relatives (Zea mays spp. parviglumis and mexicana) were surveyed for sensitivity to fumonisin B(1), a phytotoxin produced by the maize pathogen Gibberella moniliformis. Only two of 42 Z. mays samples were highly insensitive to FB(1) (ED(50) = ca. 200 microM...

journal_title：Phytochemistry

authors： Desjardins AE,Plattner RD,Stessman RJ,McCormick SP,Millard MJ

更新日期：2005-10-01 00:00:00

abstract：:A method is described for the enrichment of odd very-long-chain polyunsaturated fatty acids (VLCPUFAs) by means of RP-HPLC and argentation TLC from total fatty acids of the dinoflagellate A. carterae and their identification as picolinyl esters by means of microbore liquid chromatography-mass spectrometry with atmosph...

journal_title：Phytochemistry

authors： Rezanka T,Nedbalová L,Sigler K

更新日期：2008-11-01 00:00:00