Abstract:
:The molecular basis of human bitter taste perception is an area of intense research. Only 25 G protein-coupled receptors belonging to the hTAS2R gene family face the challenge to detect thousands of structurally different bitter compounds, most of which are plant metabolites. Since many natural bitter compounds are highly toxic, whereas others are part of our daily diets, bitter taste was crucial during evolution and still most likely affects our food selection. The article presented here addresses biosynthesis, functional analyses of TAS2Rs and TAS2R variants, as well as gustatory expression of hTAS2R genes.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Behrens M,Reichling C,Batram C,Brockhoff A,Meyerhof Wdoi
10.1111/j.1749-6632.2009.03897.xsubject
Has Abstractpub_date
2009-07-01 00:00:00pages
111-5eissn
0077-8923issn
1749-6632pii
NYAS03897journal_volume
1170pub_type
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