Populations of genomic RNAs devoted to the replication or spread of a bipartite plant virus differ in genetic structure.

abstract：:Boid inclusion body disease (BIBD) is a transmissible viral disease of captive snakes that causes severe losses in snake collections worldwide. It is caused by reptarenavirus infection, which can persist over several years without overt signs but is generally associated with the eventual death of the affected snakes. ...

journal_title：Journal of virology

authors： Argenta FF,Hepojoki J,Smura T,Szirovicza L,Hammerschmitt ME,Driemeier D,Kipar A,Hetzel U

更新日期：2020-05-18 00:00:00

abstract：:Strains of Bacillus that harbor defective phage PBSX were found to be insensitive to SP-10(C), although the phage adsorbed to these insensitive strains. Strains that did not carry the phage were sensitive to SP-10(C). B. subtilis 168 ind(-), which can be tranduced by SP-10(C) but is nonpermissive for the phage, was re...

journal_title：Journal of virology

authors： Goldberg ID,Bryan T

更新日期：1968-08-01 00:00:00

abstract：UNLABELLED:Human immunodeficiency virus type 1 (HIV-1) infection in the central nervous system (CNS) is characterized by replication in macrophages or brain microglia that express low levels of the CD4 receptor and is the cause of HIV-associated dementia and related cognitive and motor disorders that affect 20 to 30% o...

journal_title：Journal of virology

authors： Zhuang K,Leda AR,Tsai L,Knight H,Harbison C,Gettie A,Blanchard J,Westmoreland S,Cheng-Mayer C

更新日期：2014-08-01 00:00:00

abstract：UNLABELLED:The HIV-1 glycoprotein 41 promotes fusion of the viral membrane with that of the target cell. Structural, biochemical, and biophysical studies suggest that its membrane-proximal external region (MPER) may interact with the HIV-1 membrane and induce its disruption and/or deformation during the process. Howeve...

journal_title：Journal of virology

authors： Apellániz B,Rujas E,Carravilla P,Requejo-Isidro J,Huarte N,Domene C,Nieva JL

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:The distribution of vesicular stomatitis virus (VSV) nucleocapsids in the cytoplasm of infected cells was analyzed by scanning confocal fluorescence microscopy using a newly developed quantitative approach called the border-to-border distribution method. Nucleocapsids were located near the cell nucleus at ea...

journal_title：Journal of virology

authors： Yacovone SK,Smelser AM,Macosko JC,Holzwarth G,Ornelles DA,Lyles DS

更新日期：2016-06-10 00:00:00

abstract：:Regulatory elements interacting with DNA-binding proteins have been investigated in the promoter sequence of the early PE38 gene in the Autographa californica nuclear polyhedrosis virus (AcNPV). A GATA motif located 50 nucleotides upstream of the PE38 transcriptional start site is recognized differentially in the cour...

journal_title：Journal of virology

authors： Krappa R,Behn-Krappa A,Jahnel F,Doerfler W,Knebel-Mörsdorf D

更新日期：1992-06-01 00:00:00

abstract：:Tomato bushy stunt virus (TBSV), a tombusvirus with a nonsegmented, plus-stranded RNA genome, codes for two essential replicase proteins. The sequence of one of the replicase proteins, namely p33, overlaps with the N-terminal domain of p92, which contains the signature motifs of RNA-dependent RNA polymerases (RdRps) i...

journal_title：Journal of virology

authors： Rajendran KS,Nagy PD

更新日期：2003-09-01 00:00:00

abstract：:During primary varicella-zoster virus (VZV) infection, it is presumed that virus is transmitted from mucosal sites to regional lymph nodes, where T cells become infected. The cell type responsible for VZV transport from the mucosa to the lymph nodes has not been defined. In this study, we assessed the susceptibility o...

journal_title：Journal of virology

authors： Abendroth A,Morrow G,Cunningham AL,Slobedman B

更新日期：2001-07-01 00:00:00

abstract：:The contribution of the hepatitis B virus enhancers I and II in the regulation of the activity of the core and the X promoters was assessed in transgenic mice. Surprisingly, despite the presence of heterologous promoters linked 5' of the X gene, the transgene expression is mostly due to core promoter (Cp) activity pre...

journal_title：Journal of virology

authors： Billet O,Grimber G,Levrero M,Seye KA,Briand P,Joulin V

更新日期：1995-09-01 00:00:00

abstract：:Five monoclonal antibodies to the matrix (M) protein of Newcastle disease virus (NDV) Australia-Victoria (AV) strain were generated and characterized. In competitive antibody-binding assays, the antibodies fell into three discrete groups. The antigenic sites described by these antibody groups were designated M1, M2, a...

journal_title：Journal of virology

authors： Faaberg KS,Peeples ME

更新日期：1988-02-01 00:00:00

abstract：:Mutations at amino acids 143, 148, and 155 in HIV-1 integrase (IN) define primary resistance pathways in subjects failing raltegravir (RAL)-containing treatments. Although each pathway appears to be genetically distinct, shifts in the predominant resistant virus population have been reported under continued drug press...

journal_title：Journal of virology

authors： Fransen S,Gupta S,Frantzell A,Petropoulos CJ,Huang W

更新日期：2012-07-01 00:00:00

abstract：:We have studied the fate of CD4 in CEM T cells expressing a human immunodeficiency virus type 1 HIV-1 Nef protein. Nef triggered a rapid endocytosis and a degradation of CD4, while most of the p56lck was upheld at the cell membrane. In the presence of Nef, CD4 accumulated in acidic intracellular vesicles that were not...

journal_title：Journal of virology

authors： Schwartz O,Dautry-Varsat A,Goud B,Maréchal V,Subtil A,Heard JM,Danos O

更新日期：1995-01-01 00:00:00

abstract：:During the acute phase of infection with influenza A virus, the degree of lymphopenia correlates with severity of disease. Factors that contribute to T-cell activation during influenza virus infection may contribute to this observation. Since the immune response is initiated when dendritic cells (DC) interact with T c...

journal_title：Journal of virology

authors： Oh S,McCaffery JM,Eichelberger MC

更新日期：2000-06-01 00:00:00

abstract：:A novel phage lambda mutation, called dc10, which interferes with proper lambda head assembly has been isolated and characterized. Phage lambda carrying this mutation is (i) unable to form plaques at 30 or 37 degrees C but does so at 42 degrees C and (ii) unable to form plaques at 42 degrees C on pN-constitutive hosts...

journal_title：Journal of virology

authors： Georgopoulos CP,Bisig R,Magazin M,Eisen H,Court D

更新日期：1979-02-01 00:00:00

abstract：:The structure of recombinant virus-like particles of malabaricus grouper nervous necrosis virus (MGNNV), a fish nodavirus isolated from the grouper Epinephelus malabaricus, was determined by electron cryomicroscopy (cryoEM) and three-dimensional reconstruction at 23-A resolution. The cryoEM structure, sequence compari...

journal_title：Journal of virology

authors： Tang L,Lin CS,Krishna NK,Yeager M,Schneemann A,Johnson JE

更新日期：2002-06-01 00:00:00

abstract：:Hpt-13 is a Chinese hamster cell line deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) and sensitive to a medium containing 10(-4) M hypoxanthine, 5.5 X 10(-6) M aminopterin, and 10(-4) M thymidine. In this cell line there is a high incidence of cells resistant to this selective medium after an incubat...

journal_title：Journal of virology

authors： Marengo C,Mbikay M,Weber J,Thirion JP

更新日期：1981-04-01 00:00:00

abstract：:The tempo and intensity of retroviral neuropathogenesis are dependent on the capacity of the virus to invade the central nervous system. For murine leukemia viruses, an important determinant of neuroinvasiveness is the virus-encoded protein glycosylated Gag, the function of which in the virus life cycle is not known. ...

journal_title：Journal of virology

authors： Fujisawa R,McAtee FJ,Wehrly K,Portis JL

更新日期：1998-07-01 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is known to infect stem cells in the neonatal central nervous system. Here, we evaluated the effects of CVB3 infection on the major source and repository of stem cells, the bone marrow (BM). Viral genome was detectable in BM within 24 h of infection, and productive infection of BM cells was ev...

journal_title：Journal of virology

authors： Althof N,Whitton JL

更新日期：2013-03-01 00:00:00

abstract：:Gammaherpesviruses are ubiquitous pathogens that establish lifelong infections and are associated with a variety of malignancies, including lymphomas. Interferon regulatory factor 7 (IRF-7) is an innate immune transcription factor that restricts acute replication of diverse viruses, including murine gammaherpesvirus 6...

journal_title：Journal of virology

authors： Johnson KE,Aurubin CA,Jondle CN,Lange PT,Tarakanova VL

更新日期：2020-11-23 00:00:00

abstract：:Friend murine spleen focus-forming virus (SFFV) encodes a glycoprotein designated gp52, which is responsible for the leukemogenic properties of the virus. gp52 lacks a cytoplasmic domain and is defective in its transport to the cell surface. We constructed a chimeric envelope gene which codes for a molecule with an ex...

journal_title：Journal of virology

authors： Srinivas RV,Kilpatrick DR,Compans RW

更新日期：1987-12-01 00:00:00

abstract：:Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that causes neurological diseases in a variety of warm-blooded animal species. There is general consensus that BDV can also infect humans, being a possible zoonosis. Although the clinical consequences of human BDV infection are still controversial,...

journal_title：Journal of virology

authors： Bajramovic JJ,Syan S,Brahic M,de la Torre JC,Gonzalez-Dunia D

更新日期：2002-06-01 00:00:00

abstract：:Two strains of minute virus of mice (MVM) show different host cell specificities. The prototype strain MVM(p) grows in fibroblasts, whereas the immunosuppressive variant MVM(i) grows in T lymphocytes. In this study, we have mapped on the viral genome a cell type-specific determinant: it is located between 69 and 85 ma...

journal_title：Journal of virology

authors： Antonietti JP,Sahli R,Beard P,Hirt B

更新日期：1988-02-01 00:00:00

abstract：:Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [aa] 61 to 87 using PB1-F2 amino acid numbering) of the PB1-F2-derived C-terminal peptides from influenza A viruses inducing high or low levels of cell death, we identif...

journal_title：Journal of virology

authors： Alymova IV,Samarasinghe A,Vogel P,Green AM,Weinlich R,McCullers JA

更新日期：2014-01-01 00:00:00

abstract：:Transgene expression after the administration of recombinant adenovirus with E1 deleted is constantly transient. It is admitted that E1A-substituting activities of cellular or viral origin allow viral antigen synthesis and trigger cytotoxic lymphocyte-mediated clearance of the recipient cells. Our approach to solving ...

journal_title：Journal of virology

authors： Yeh P,Dedieu JF,Orsini C,Vigne E,Denefle P,Perricaudet M

更新日期：1996-01-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) accessory protein Vpu enhances virus particle release by counteracting a host factor that retains virions at the surfaces of infected cells. It was recently demonstrated that cellular protein BST-2/CD317/Tetherin restricts HIV-1 release in a Vpu-dependent manner. Calcium...

journal_title：Journal of virology

authors： Bego MG,Dubé M,Mercier J,Cohen EA

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:Since the 1960s, simian hemorrhagic fever virus (SHFV; Nidovirales, Arteriviridae) has caused highly fatal outbreaks of viral hemorrhagic fever in captive Asian macaque colonies. However, the source(s) of these outbreaks and the natural reservoir(s) of this virus remain obscure. Here we report the identifica...

journal_title：Journal of virology

authors： Bailey AL,Lauck M,Sibley SD,Pecotte J,Rice K,Weny G,Tumukunde A,Hyeroba D,Greene J,Correll M,Gleicher M,Friedrich TC,Jahrling PB,Kuhn JH,Goldberg TL,Rogers J,O'Connor DH

更新日期：2014-11-01 00:00:00

abstract：:Transcription and replication signals within the negative-sense genomic RNA of vesicular stomatitis virus (VSV) are located at the 3' terminus. To identify these signals, we have used a transcription- and replication-competent minigenome of VSV to generate a series of deletions spanning the first 47 nucleotides at the...

journal_title：Journal of virology

authors： Li T,Pattnaik AK

更新日期：1999-01-01 00:00:00

abstract：:The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) host cell passages. High and low multiplicities were used to examine the effect of de...

journal_title：Journal of virology

authors： Weaver SC,Brault AC,Kang W,Holland JJ

更新日期：1999-05-01 00:00:00

abstract：:We have previously shown that two inhibitors specific for cellular cyclin-dependent kinases (cdks), Roscovitine (Rosco) and Olomoucine (Olo), block the replication of herpes simplex virus (HSV). Based on these results, we demonstrated that HSV replication requires cellular cdks that are sensitive to these drugs (L. M....

journal_title：Journal of virology

authors： Schang LM,Rosenberg A,Schaffer PA

更新日期：2000-03-01 00:00:00

abstract：:The membrane fusion events which initiate human immunodeficiency virus type 1 (HIV-1) infection and promote cytopathic syncytium formation in infected cells commence with the binding of the HIV envelope glycoprotein (Env) to CD4 and an appropriate coreceptor. Here, we show that HIV Env-coreceptor interactions activate...

journal_title：Journal of virology

authors： Pontow SE,Heyden NV,Wei S,Ratner L

更新日期：2004-07-01 00:00:00