Tropical spastic paraparesis-like illness occurring in a patient dually infected with HIV-1 and HTLV-II.

abstract：OBJECTIVE:To determine the role of oxidative stress in mediating HIV dementia and to identify novel therapeutic compounds that may block this oxidative stress. METHODS:Brain tissue from patients with HIV encephalitis and macaques with simian immune deficiency virus encephalitis was immunostained for lipid peroxidation...

journal_title：Neurology

authors： Turchan J,Pocernich CB,Gairola C,Chauhan A,Schifitto G,Butterfield DA,Buch S,Narayan O,Sinai A,Geiger J,Berger JR,Elford H,Nath A

更新日期：2003-01-28 00:00:00

abstract：:Supporting young people with pediatric multiple sclerosis can be challenging for families and health care providers. Adolescents may be more resilient than adults in reaction to the diagnosis but can have more difficulty planning for their futures. Appropriate, sensitive, and focused health provision should include co...

journal_title：Neurology

authors： Krupp LB,Rintell D,Charvet LE,Milazzo M,Wassmer E

更新日期：2016-08-30 00:00:00

abstract：OBJECTIVE:To report outcomes of pregnancies that occurred during the fingolimod clinical development program. METHODS:Pregnancy outcomes from phase II, phase III, and phase IV clinical studies (with optional extensions) were reported by clinical trial investigators. Fingolimod exposure in utero was defined as fingolim...

journal_title：Neurology

authors： Karlsson G,Francis G,Koren G,Heining P,Zhang X,Cohen JA,Kappos L,Collins W

更新日期：2014-02-25 00:00:00

abstract：OBJECTIVE:To investigate the relationships between structural damage in the whole brain, the temporal lobes, and the frontal lobes and cognitive decline at old age. The authors hypothesized that widespread brain damage as quantified using magnetization transfer imaging (MTI) is related to global cognitive decline, wher...

journal_title：Neurology

authors： Van Der Flier WM,Van Den Heuvel DM,Weverling-Rijnsburger AW,Spilt A,Bollen EL,Westendorp RG,Middelkoop HA,Van Buchem MA

更新日期：2002-09-24 00:00:00

abstract：:We evaluated four formulas for estimating the intra-blood-brain barrier (IBBB) synthesis of IgG in a computer model of two types of BBB damage and in 1,629 consecutively received pairs of CSF and serum. These four formulas were the IgG synthesis rate (SR), IgG(loc) (ie, local), IgG index, and IgG extended index. Resul...

journal_title：Neurology

authors： Peter JB,Bowman RL

更新日期：1992-03-01 00:00:00

abstract：:Kuru plaques are the pathologic hallmark in Gerstmann-Sträussler syndrome (GSS). To demonstrate that prion protein (PrP) is a component of kuru plaque cores, we fractionated and sequenced kuru plaque core derived peptides, following digestion with Achromobacter lyticus protease I. We identified 3 PrP-derived peptides ...

journal_title：Neurology

authors： Kitamoto T,Yamaguchi K,Doh-ura K,Tateishi J

更新日期：1991-02-01 00:00:00

abstract：:A 42-year-old man had progressive distal weakness and muscle atrophy, stocking-type sensory loss, upper motor-neuron and visual pathway lesions, and dysautonomia. Electrodiagnostic tests revealed a generalized sensorimotor peripheral neuropathy that largely involved axons. Low recumbent and upright norepinephrine leve...

journal_title：Neurology

authors： Rechthand E,Reife R,Kaplan JG

更新日期：1983-11-01 00:00:00

abstract：:INeuro@neurolist.mcg. edu: An e-mail discussion list for neurologists Neuro@neurolist.mcg.edu (Neurolist) is a discussion list for neurologists. This Internet tool, established in 1994, allows the worldwide community of neurologists to communicate quickly and efficiently using e-mail, web browsers, and newsreaders. Ne...

journal_title：Neurology

authors： Rivner MH

更新日期：1999-06-10 00:00:00

abstract：:In the present study we compared the efficacy and safety of the new dopamine agonist cabergoline (CBG) with bromocriptine (BCR) in Parkinson's disease (PD). CBG has a very long half-life and can be administered as a single daily dose. Forty-four PD patients with uncontrolled motor fluctuations participated in the stud...

journal_title：Neurology

authors： Inzelberg R,Nisipeanu P,Rabey JM,Orlov E,Catz T,Kippervasser S,Schechtman E,Korczyn AD

更新日期：1996-09-01 00:00:00

abstract：:Using a 1.5-tesla GE Signa MR scanner, we imaged the brains of 14 right-handed Tourette's syndrome (TS) patients (11 men, three women), aged 18 to 49 years, who had minimal lifetime neuroleptic exposure. We also studied an equal number of normal controls individually matched for age, sex, and handedness and group-matc...

journal_title：Neurology

authors： Peterson B,Riddle MA,Cohen DJ,Katz LD,Smith JC,Hardin MT,Leckman JF

更新日期：1993-05-01 00:00:00

abstract：:Pathologic changes and distribution of lesions of the spinal cord were studied in 16 patients who suffered from "anoxic" episodes. The lesions were symmetrical and limited to the gray matter. The vulnerability of the spinal cord was most marked in the lumbosacral region, although almost every nucleus throughout the sp...

journal_title：Neurology

authors： Azzarelli B,Roessmann U

更新日期：1977-11-01 00:00:00

abstract：OBJECTIVE:To determine factors (including the role of specific disease modulatory treatments [DMTs]) associated with (1) baseline, (2) on-treatment, and (3) change (from treatment start to on-treatment assessment) in plasma neurofilament light chain (pNfL) concentrations in relapsing-remitting multiple sclerosis (RRMS)...

journal_title：Neurology

authors： Delcoigne B,Manouchehrinia A,Barro C,Benkert P,Michalak Z,Kappos L,Leppert D,Tsai JA,Plavina T,Kieseier BC,Lycke J,Alfredsson L,Kockum I,Kuhle J,Olsson T,Piehl F

更新日期：2020-03-17 00:00:00

abstract：:In 10 patients with chronic autonomic failure, the sympathetic perivascular nerve plexuses from quadriceps muscle biopsies were studied by catecholamine fluorescence and electronmicroscopy. There was almost complete absence of catecholamine fluorescence and fewer than normal numbers of small granular (noradrenergic) v...

journal_title：Neurology

authors： Bannister R,Crowe R,Eames R,Burnstock G

更新日期：1981-12-01 00:00:00

abstract：:We studied 20 patients with an acute parietal stroke with hemisensory disturbances but no visual field deficit and no or only slight motor weakness, without thalamic involvement on CT or MRI and found three main sensory syndromes. (1) The pseudothalamic sensory syndrome consists of a faciobrachiocrural impairment of e...

journal_title：Neurology

authors： Bassetti C,Bogousslavsky J,Regli F

更新日期：1993-10-01 00:00:00

abstract：:Four men with evidence of hemiatrophy resulting from early-life hemispheral injury developed unilateral hemiparkinsonism on the side of the hemiatrophy. The parkinsonism began in the fourth decade and has remained unilateral for 5 to 35 years. In all four patients, the parkinsonism was slowly progressive, but the clin...

journal_title：Neurology

authors： Klawans HL

更新日期：1981-05-01 00:00:00

abstract：OBJECTIVE:To evaluate an observational-behavioral pain tool among individuals with acute poststroke aphasia. METHODS:We performed a randomized, double-blind, controlled study of experimental pain assessment among 36 adult patients with acute poststroke aphasia. Patients were administered 3 levels of mechanical pain, i...

journal_title：Neurology

authors： Soares CD,Panuganti PK,Shrivastava A,Aroor S,Keinath KM,Bromagen MC,Howard ME,Carlson C,Smith JH

更新日期：2018-08-28 00:00:00

abstract：BACKGROUND:According to widely used criteria (Bohan and Peter criteria, 1975), dermatomyositis (DM) is differentiated from polymyositis (PM) only by skin changes. More recent criteria also include histopathologic characteristics enabling the distinction between PM and DM and the differentiation of sporadic inclusion bo...

journal_title：Neurology

authors： van der Meulen MF,Bronner IM,Hoogendijk JE,Burger H,van Venrooij WJ,Voskuyl AE,Dinant HJ,Linssen WH,Wokke JH,de Visser M

更新日期：2003-08-12 00:00:00

abstract：:Isovaleric acidemia (IVA) is an inborn error of leucine metabolism, resulting in an accumulation of isovaleric acid in the body fluids. The neuropathologic findings in an 11-day-old infant with IVA consisted of diffuse cerebral edema, massive cerebellar hemorrhage, upward transtentorial herniation, and focal degenerat...

journal_title：Neurology

authors： Fischer AQ,Challa VR,Burton BK,McLean WT

更新日期：1981-06-01 00:00:00

abstract：:The term "Wernicke's area" is most often used as an anatomical label for the gyri forming the lower posterior left sylvian fissure. Although traditionally this region was held to support language comprehension, modern imaging and neuropsychological studies converge on the conclusion that this region plays a much large...

journal_title：Neurology

authors： Binder JR

更新日期：2015-12-15 00:00:00

abstract：OBJECTIVE:To examine the lifetime prevalence and the concordance risk of cluster headache (CH) in a twin sample representative of the Swedish general population. METHODS:The authors assessed CH as defined by the second edition of the International Classification of Headache Disorders in 31,750 registered twins born fr...

journal_title：Neurology

authors： Ekbom K,Svensson DA,Pedersen NL,Waldenlind E

更新日期：2006-09-12 00:00:00

abstract：:Inhibitory antibody to von Willebrand factor (vWF)-cleaving protease (ADAMTS13) was detected in a patient with intravascular lymphomatosis. The increased serum level of the antibody paralleled an increase in the expression of uncleaved vWF, which might cause microvascular thrombosis and platelet consumption. Malignant...

journal_title：Neurology

authors： Kawahara M,Kanno M,Matsumoto M,Nakamura S,Fujimura Y,Ueno S

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:Two recent studies suggest that the risk of ALS is increased among Gulf War veterans. It is not known whether military service outside of the Gulf War is associated with increased risk of ALS. METHODS:The authors prospectively assessed the relation between service in the military and ALS mortality among par...

journal_title：Neurology

authors： Weisskopf MG,O'Reilly EJ,McCullough ML,Calle EE,Thun MJ,Cudkowicz M,Ascherio A

更新日期：2005-01-11 00:00:00

abstract：OBJECTIVE:To describe neurodevelopment and head growth in HIV-1-infected and exposed uninfected infants with and without in utero exposure to opiates and cocaine. METHODS:Using data from a multicenter cohort study of HIV-1-infected women and their children, the authors fit repeated measures regression models to estima...

journal_title：Neurology

authors： Macmillan C,Magder LS,Brouwers P,Chase C,Hittelman J,Lasky T,Malee K,Mellins CA,Velez-Borras J

更新日期：2001-10-23 00:00:00

abstract：OBJECTIVE:To determine the efficacy and tolerability of unilateral thalamic deep brain stimulation (DBS) for patients with medically refractory essential tremor (ET) and the tremor associated with Parkinson's disease (PD). BACKGROUND:The tremor of ET and PD may produce functional disability despite optimal medical the...

journal_title：Neurology

authors： Ondo W,Jankovic J,Schwartz K,Almaguer M,Simpson RK

更新日期：1998-10-01 00:00:00

abstract：:A clinical procedure for determining contrast sensitivity was performed on patients with suspected sella area masses. The test consisted of a series of six plates, each containing a bar pattern of fixed sinusoidal spatial frequency in which contrast varies along the length of the bar. Patients with compressive lesions...

journal_title：Neurology

authors： Kupersmith MJ,Siegel IM,Carr RE

更新日期：1981-05-01 00:00:00

abstract：:Oligoclonal bands ( OCBs ) were examined in CSF from 23 normal controls, 8 cases of inflammatory neurologic diseases, 24 cases of noninflammatory neurologic diseases, 27 sporadic cases of MS, and the 29 MS twin pairs, by isoelectric focusing followed by silver staining or western transblotting and immunoperoxidase sta...

journal_title：Neurology

authors： Xu XH,McFarlin DE

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that concussion-related brain alterations seen at symptomatic injury and medical clearance to return to play (RTP) will have dissipated by 1 year after RTP. METHODS:For this observational study, 24 athletes with concussion were scanned longitudinally within 1 week after injury, at RTP,...

journal_title：Neurology

authors： Churchill NW,Hutchison MG,Graham SJ,Schweizer TA

更新日期：2019-11-19 00:00:00

abstract：:Intracranial hypertension in the absence of an intracranial mass lesion or hydrocephalus can be caused by an alteration of one or more of the four determinants of cerebrospinal fluid (CSF) pressure: (1) intrasagittal sinus pressure, (2) resistance of arachnoid villi to the egress of CSF, (3) rate of production of CSF,...

journal_title：Neurology

authors： Donaldson JO

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS). METHODS:Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychoso...

journal_title：Neurology

authors： Rabkin J,Goetz R,Murphy JM,Factor-Litvak P,Mitsumoto H,ALS COSMOS Study Group.

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVE:To investigate the pathogenesis of proximal diabetic neuropathy (PDN) with nerve and muscle biopsies. BACKGROUND:Recent evidence suggests that nerve ischemia secondary to immune-mediated vasculopathy rather than diabetic microangiopathy may be responsible for PDN. METHOD:- Fifteen patients with PDN and two ...

journal_title：Neurology

authors： Kelkar P,Masood M,Parry GJ

更新日期：2000-07-12 00:00:00