Temporal profiling of rat transcriptomes in retinol-replenished vitamin A-deficient testis.

abstract：:Primary ovarian insufficiency (POI) affects ~1% of women in the general population. Despite numerous attempts at identifying POI genetic aetiology, coding mutations in only a few genes have been functionally related to POI pathogenesis. It has been suggested that mutant BMPR2 might contribute towards the phenotype. Se...

journal_title：Systems biology in reproductive medicine

authors： Patiño LC,Silgado D,Laissue P

更新日期：2017-06-01 00:00:00

abstract：:In order to identify unreliable data in a dataset of motility parameters obtained from a pilot study acquired by a veterinarian with experience in boar semen handling, but without experience in the operation of a computer assisted sperm analysis (CASA) system, a multivariate graphical and statistical analysis was perf...

journal_title：Systems biology in reproductive medicine

authors： Martínez LB,Crispín RH,Mendoza MM,Gallegos OH,Martínez AA

更新日期：2013-06-01 00:00:00

abstract：:Both microdrop and open methods are commonly used for in vitro fertilization (IVF) protocols for embryo culture as well as oocyte insemination. However, few comparative studies evaluating the microdrop or open method of insemination on the fertilization outcome and subsequent embryo development have been performed. A ...

journal_title：Systems biology in reproductive medicine

authors： Li Y,Li T,Mai Q,Long L,Ou J

更新日期：2014-06-01 00:00:00

abstract：:Complete deletions in the AZF (a, b, and c) sub-regions of the Y-chromosome have been shown to contribute to unexplained male infertility. However, the role of partial AZFc deletions in male infertility remains to be verified. Three types of partial AZFc deletions have been identified. They are gr/gr, b1/b3, and b2/b3...

journal_title：Systems biology in reproductive medicine

authors： Almeamar HA,Ramachandran V,Ismail P,Nadkarni P,Fawzi N

更新日期：2013-04-01 00:00:00

abstract：:We aimed to assess the possible presence of a seasonal pattern in three parameters of semen analysis: sperm concentration, morphology, and motility as a function of the time of ejaculation and sperm production (spermatogenesis) in normal and oligozoospermic men. This retrospective study included a consecutive series o...

journal_title：Systems biology in reproductive medicine

authors： Ozelci R,Yılmaz S,Dilbaz B,Akpınar F,Akdag Cırık D,Dilbaz S,Ocal A

更新日期：2016-12-01 00:00:00

abstract：:Maternal obesity can cause complications for both women and their offspring for generations. Therefore, we intended to verify the repercussions of induction of transgenerational obesity on biochemical parameters, reproductive performance, and congenital anomaly frequency in Wistar rats. Female rats were used from succ...

journal_title：Systems biology in reproductive medicine

authors： Soares TS,Andreolla AP,Miranda CA,Klöppel E,Rodrigues LS,Moraes-Souza RQ,Damasceno DC,Volpato GT,Campos KE

更新日期：2018-02-01 00:00:00

abstract：:Assisted reproductive technology has evolved tremendously since the emergence of in vitro fertilization (IVF). In the course of the recent decade, there have been significant efforts in order to minimize multiple gestations, while improving percentages of singleton pregnancies and offering individualized services in I...

journal_title：Systems biology in reproductive medicine

authors： Simopoulou M,Sfakianoudis K,Antoniou N,Maziotis E,Rapani A,Bakas P,Anifandis G,Kalampokas T,Bolaris S,Pantou A,Pantos K,Koutsilieris M

更新日期：2018-10-01 00:00:00

abstract：:The aim of this study was to evaluate the feasibility and efficiency of using a sucrose gradient-based warming protocol as a universal warming approach on human cleavage stage embryos. Between January 2013 and November 2014, a total of 118 warming cycles were performed on 705 embryos which had previously been cryopres...

journal_title：Systems biology in reproductive medicine

authors： Serdarogullari M,Coban O,Boynukalin FK,Bilgin EM,Findikli N,Bahceci M

更新日期：2019-02-01 00:00:00

abstract：:What is the impact of intentional weight loss and regain on serum androgens in women? We conducted an ancillary analysis of prospectively collected samples from a randomized controlled trial. The trial involved supervised 10% weight loss (8.5 kg on average) with diet and exercise over 4-6 months followed by supervised...

journal_title：Systems biology in reproductive medicine

authors： Aubuchon M,Liu Y,Petroski GF,Thomas TR,Polotsky AJ

更新日期：2016-08-01 00:00:00

abstract：:Artificial insemination has achieved a dynamic increase in genetic progress, and this is due to the improvement of sperm preservation technology. In recent years, a lot of attention has been paid to optimizing bull sperm storage environment and objectifying methods of sperm quality analysis. This review presents bull ...

journal_title：Systems biology in reproductive medicine

authors： Kowalczyk A,Kuczaj M,Czerniawska-Piątkowska E

更新日期：2020-10-01 00:00:00

abstract：:Assessment of sperm DNA damage has been suggested as a negative predictor of fertility potential. Multiple pathological factors acting at both the intra-testicular and post-testicular levels may contribute to sperm DNA damage. The relative contribution of each of these factors in an individual with high DNA damage (>3...

journal_title：Systems biology in reproductive medicine

authors： Moskovtsev SI,Lecker I,Mullen JB,Jarvi K,Willis J,White J,Lo KC

更新日期：2009-03-01 00:00:00

abstract：:The etiology of adverse pregnancy outcomes is not well understood. Wildlife observations provide considerable evidence that environmental contaminants can play a critical role in reproductive and developmental dysfunction. Early evidence leading to a widespread awareness of the impact of environmental chemicals on sur...

journal_title：Systems biology in reproductive medicine

authors： Hamlin HJ,Guillette LJ Jr

更新日期：2010-04-01 00:00:00

abstract：:In many species, extended semen can be stored at low temperatures to slow bacterial growth. However, boar semen performs poorly at temperatures below 15 °C and this poses unique challenges, as it is not easy to maintain a constant 15-19 °C during shipment. Some extenders have been formulated with egg yolk for storage ...

journal_title：Systems biology in reproductive medicine

authors： Casas I,Miller-Lux Y,Osborne B,Bonet S,Althouse GC

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study is to compare the pregnancy and live birth rates of a natural cycle in vitro fertilization (IVF) combined with in vitro maturation (IVM) treatment (natural cycle IVF/M) by the presence or absence of mature oocytes retrieved. Infertile women were divided into two groups: (A) patients with ma...

journal_title：Systems biology in reproductive medicine

authors： Yang SH,Patrizio P,Yoon SH,Lim JH,Chian RC

更新日期：2012-06-01 00:00:00

abstract：:The object of this study was to investigate the effect of molybdenum on the development of mouse preimplantation embryos cultured in vitro. Zygotes were flushed from one outbred mouse strain (Kunming), and then were cultured in potassium simplex optimized medium (KSOM) containing 0, 5, 10, 20, 40, 80, 120, and 160 µg/...

journal_title：Systems biology in reproductive medicine

authors： Bi CM,Zhang YL,Liu FJ,Zhou TZ,Yang ZJ,Gao SY,Wang SD,Chen XL,Zhai XW,Ma XG,Jin LJ,Wang S

更新日期：2013-04-01 00:00:00

abstract：:The aim of this study is to compare the expression patterns of tyrosine kinases and their ligand activators between matched myometrium and leiomyoma tissues. Total RNA extracted from 42 pairs of matched leiomyomal and adjacent myometrial tissues were hybridized to a set of 840 customized oligonucleotide microarrays to...

journal_title：Systems biology in reproductive medicine

authors： Jiang Y,Suo G,Sadarangani A,Cowan B,Wang JY

更新日期：2010-08-01 00:00:00

abstract：:Phthalates are ubiquitous industrial chemicals that are reported to adversely affect human reproductive outcomes. Divergent effects on semen quality have been reported in a limited number of studies. To assess the possible contribution of regional differences in phthalate exposure to these results, we wished to determ...

journal_title：Systems biology in reproductive medicine

authors： Wirth JJ,Rossano MG,Potter R,Puscheck E,Daly DC,Paneth N,Krawetz SA,Protas BM,Diamond MP

更新日期：2008-05-01 00:00:00

abstract：:The study of embryos with the tools and mindset of physics, started by Wilhelm His in the 1880s, has resumed after a hiatus of a century. The Embryo Physics Course convenes online allowing interested researchers and students, who are scattered around the world, to gather weekly in one place, the virtual world of Secon...

journal_title：Systems biology in reproductive medicine

authors： Gordon R

更新日期：2013-06-01 00:00:00

abstract：:Varicocele is currently the most common irregularity identified in males that is associated with impaired spermatogenesis. It primarily presents in the form of decreased sperm count and motility, abnormal morphology, and significantly increased sperm DNA fragmentation. Several studies have shown that surgical repair i...

journal_title：Systems biology in reproductive medicine

authors： Li F,Yamaguchi K,Okada K,Matsushita K,Ando M,Chiba K,Yue H,Fujisawa M

更新日期：2012-10-01 00:00:00

abstract：:During spermatogenesis, changes in sperm nuclear morphology are associated with the replacement of core somatic histones by protamines. Although protamines are the major nucleoproteins of mature sperm, not all species totally replace the histones. Histone H1, along with protamines, mediates chromatin condensation into...

journal_title：Systems biology in reproductive medicine

authors： Sánchez-Vázquez ML,Flores-Alonso JC,Merchant-Larios H,Reyes R

更新日期：2008-11-01 00:00:00

abstract：:Preimplantation embryos may have an increased risk of having mismatches due to the rates of cell proliferation and DNA replication. Elimination of mismatches in human gametes and embryos has not been investigated. In this study we developed a sensitive functional assay to examine the repair or elimination of mismatche...

journal_title：Systems biology in reproductive medicine

authors： Tulay P,Jaroudi S,Doshi A,SenGupta SB

更新日期：2016-12-01 00:00:00

abstract：:A very common conception about the function of the spermatozoon is that its unique role is to transmit the paternal genome to the next generation. Most of the sperm genome is known to be condensed in many species by protamines, which are small and extremely positively charged proteins (50-70% arginine) with the functi...

journal_title：Systems biology in reproductive medicine

authors： Barrachina F,Anastasiadi D,Jodar M,Castillo J,Estanyol JM,Piferrer F,Oliva R

更新日期：2018-12-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF), a major angiogenic factor, is known to play an important role in the development of endometriosis. The aim of this study was to investigate the association of three VEGF (-460 C/T, +405 G/C, and +936 C/T) polymorphisms with the risk of endometriosis in the Tunisian popula...

journal_title：Systems biology in reproductive medicine

authors： Henidi B,Kaabachi W,Naouali A,Kaabachi S,Zhioua A,Haj Sassi F,Hamzaoui K

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate the predictive value of the anti-Mullerian hormone (AMH) level for early pregnancy loss and to compare the significance of AMH level to age as prognostic factors of pregnancy loss in subfertile women. The outcome of 848 subfertile patients confirmed with intrauterine pregnancies b...

journal_title：Systems biology in reproductive medicine

authors： Hong S,Chang E,Han EJ,Min SG,Kim S,Kang MK,Cha DH,Shim SH,Park HJ

更新日期：2020-12-01 00:00:00

abstract：:The GIRK2-containing inward-rectifying K(+) ion channels have been implicated in mammalian spermatogenesis. While the Girk2 null mice are fertile, the male weaver transgenic mice carrying a gain-of-function mutation in the Girk2 gene are infertile. To establish the exact period of spermatogenesis affected by this muta...

journal_title：Systems biology in reproductive medicine

authors： Yi YJ,Sung DY,Millette C,Sutovsky M,Kennedy C,Sutovsky P,Thompson W,Thomas K

更新日期：2011-12-01 00:00:00

abstract：:Increased trophoblast apoptosis has been implicated in pregnancies complicated by fetal growth restriction and preeclampsia (EC). We investigated placenta growth factor (PLGF) signaling during trophoblast apoptosis in culture and X-linked inhibitor of apoptosis protein (XIAP) and apoptosis inducible factor (AIF) in th...

journal_title：Systems biology in reproductive medicine

authors： Arroyo J,Price M,Straszewski-Chavez S,Torry RJ,Mor G,Torry DS

更新日期：2014-10-01 00:00:00

abstract：:FSH in infertile patients may be measured in the normal range and abnormal semen analysis findings may be observed in patients with normal FSH values. A recent study predicts that the sperm morphology and concentration may be impaired if the FSH value is above 4.5 IU/L. Therefore, this study aimed to define a clinical...

journal_title：Systems biology in reproductive medicine

authors： Ozkaya M,Oztekin U,Caniklioglu M,Ekmekcioglu O

更新日期：2020-10-01 00:00:00

abstract：:Multiple prevention therapy has gained importance for the prevention and treatment of sexually transmitted diseases, especially HIV/AIDS. Antiretroviral drugs encapsulated in nanoparticles have been developed for efficient delivery of the drugs to the vaginal surface. Lactoferrin nanoparticles (LFNPs) encapsulating an...

journal_title：Systems biology in reproductive medicine

authors： Madugulla L,Ravula AR,Kondapi AK,Yenugu S

更新日期：2019-06-01 00:00:00

abstract：:One of the major causes of defective sperm function is oxidative stress, which limits the fertilizing potential of these cells as the result of collateral damage to proteins and lipids in the sperm plasma membrane. On this point, a derangement of both generation and neutralization of reactive oxygen species (ROS) is a...

journal_title：Systems biology in reproductive medicine

authors： Signorini C,Moretti E,Collodel G

更新日期：2020-10-01 00:00:00

abstract：:We have earlier shown that cobalt chloride (CoCl2)-induced hypoxia and second messenger 8-bromoadenosine 3', 5'-cyclic adenosine monophosphate (8-Br-cAMP) stimulates vascular endothelial growth factor (VEGF) production in Leydig tumor cell derived MA-10 cells. Both stimuli follow common signal transduction pathways in...

journal_title：Systems biology in reproductive medicine

authors： Kumar A,Rani L,Dhole B

更新日期：2014-04-01 00:00:00