The anti-Mullerian hormone as a predictor of early pregnancy loss in subfertile women.

abstract：:One of the major causes of defective sperm function is oxidative stress, which limits the fertilizing potential of these cells as the result of collateral damage to proteins and lipids in the sperm plasma membrane. On this point, a derangement of both generation and neutralization of reactive oxygen species (ROS) is a...

journal_title：Systems biology in reproductive medicine

authors： Signorini C,Moretti E,Collodel G

更新日期：2020-10-01 00:00:00

abstract：:In the human, canonical histones are largely replaced by protamine 1 (P1) and protamine 2 (P2) during late spermatogenesis. Recent studies have demonstrated that abnormal replacement of the histones is associated with severe male infertility and has profound implications for early embryogenesis. In this review the his...

journal_title：Systems biology in reproductive medicine

authors： Nanassy L,Griffin J,Emery BR,Carrell DT

更新日期：2010-06-01 00:00:00

abstract：:The aim of this study was to evaluate the feasibility and efficiency of using a sucrose gradient-based warming protocol as a universal warming approach on human cleavage stage embryos. Between January 2013 and November 2014, a total of 118 warming cycles were performed on 705 embryos which had previously been cryopres...

journal_title：Systems biology in reproductive medicine

authors： Serdarogullari M,Coban O,Boynukalin FK,Bilgin EM,Findikli N,Bahceci M

更新日期：2019-02-01 00:00:00

abstract：:We explored the molecular mechanisms of obesity and insulin resistance in patients with polycystic ovary syndrome (PCOS) using a human embryonic stem cell model (hESCs). Three PCOS-derived and one non-PCOS-derived hESC lines were induced into adipocytes, and then total RNA was extracted. The differentially expressed P...

journal_title：Systems biology in reproductive medicine

authors： Wang F,Liu WW,Chen XM,Kong HJ,Li J,Sun YP

更新日期：2014-06-01 00:00:00

abstract：:We aimed to survey the monogenic causes of disorders of sex development (DSD) and thereby its prevalence in India. This study revealed mutations resulting in androgen insensitivity syndrome, 5α-reductase type 2 deficiency, and gonadal dysgenesis were commonly reported. Intriguingly, AR deficits were the most prevalent...

journal_title：Systems biology in reproductive medicine

authors： Nagaraja MR,Gubbala SP,Delphine Silvia CRW,Amanchy R

更新日期：2019-04-01 00:00:00

abstract：:Varicocele is currently the most common irregularity identified in males that is associated with impaired spermatogenesis. It primarily presents in the form of decreased sperm count and motility, abnormal morphology, and significantly increased sperm DNA fragmentation. Several studies have shown that surgical repair i...

journal_title：Systems biology in reproductive medicine

authors： Li F,Yamaguchi K,Okada K,Matsushita K,Ando M,Chiba K,Yue H,Fujisawa M

更新日期：2012-10-01 00:00:00

abstract：:In this retrospective study the outcomes of two protocols of controlled ovarian hyperstimulation and natural cycle in poor ovarian responders defined according to the Bologna criteria were compared to elucidate which approach is more suitable for the treatment of these patients. We comparatively analyzed 142 cycles of...

journal_title：Systems biology in reproductive medicine

authors： Stimpfel M,Vrtačnik-Bokal E,Pozlep B,Kmecl J,Virant-Klun I

更新日期：2016-08-01 00:00:00

abstract：:At least in mammals, retinoic acid is a pivotal factor in maintaining the functionality of the testis, in particular, for the progression of germ cells from mitosis to meiosis. Removal of dietary vitamin A or a targeted deletion of retinoic acid receptor alpha gene (Rara), the receptor for retinoic acid, in mice, led ...

journal_title：Systems biology in reproductive medicine

authors： Doyle TJ,Oudes AJ,Kim KH

更新日期：2009-08-01 00:00:00

abstract：:The aim of this study is to compare the expression patterns of tyrosine kinases and their ligand activators between matched myometrium and leiomyoma tissues. Total RNA extracted from 42 pairs of matched leiomyomal and adjacent myometrial tissues were hybridized to a set of 840 customized oligonucleotide microarrays to...

journal_title：Systems biology in reproductive medicine

authors： Jiang Y,Suo G,Sadarangani A,Cowan B,Wang JY

更新日期：2010-08-01 00:00:00

abstract：:For natural fertilization to occur successfully, millions of spermatozoa must be deposited in the lower end of the female genital tract during mating. Considerably fewer spermatozoa are required for fertilization when spermatozoa are deposited in the upper region of the female tract. The extreme case of assisted ferti...

journal_title：Systems biology in reproductive medicine

authors： Yanagimachi R

更新日期：2011-02-01 00:00:00

abstract：:Genomic disorders are defined as diseases caused by rearrangements of the genome incited by a genomic architecture that conveys instability. Y-chromosome related dysfunctions such as male infertility are frequently associated with gross DNA rearrangements resulting from its peculiar genomic architecture. The Y-chromos...

journal_title：Systems biology in reproductive medicine

authors： Carvalho CM,Zhang F,Lupski JR

更新日期：2011-02-01 00:00:00

abstract：:The GIRK2-containing inward-rectifying K(+) ion channels have been implicated in mammalian spermatogenesis. While the Girk2 null mice are fertile, the male weaver transgenic mice carrying a gain-of-function mutation in the Girk2 gene are infertile. To establish the exact period of spermatogenesis affected by this muta...

journal_title：Systems biology in reproductive medicine

authors： Yi YJ,Sung DY,Millette C,Sutovsky M,Kennedy C,Sutovsky P,Thompson W,Thomas K

更新日期：2011-12-01 00:00:00

abstract：:Phthalates are ubiquitous industrial chemicals that are reported to adversely affect human reproductive outcomes. Divergent effects on semen quality have been reported in a limited number of studies. To assess the possible contribution of regional differences in phthalate exposure to these results, we wished to determ...

journal_title：Systems biology in reproductive medicine

authors： Wirth JJ,Rossano MG,Potter R,Puscheck E,Daly DC,Paneth N,Krawetz SA,Protas BM,Diamond MP

更新日期：2008-05-01 00:00:00

abstract：:Primary ovarian insufficiency (POI) affects ~1% of women in the general population. Despite numerous attempts at identifying POI genetic aetiology, coding mutations in only a few genes have been functionally related to POI pathogenesis. It has been suggested that mutant BMPR2 might contribute towards the phenotype. Se...

journal_title：Systems biology in reproductive medicine

authors： Patiño LC,Silgado D,Laissue P

更新日期：2017-06-01 00:00:00

abstract：:In many species, extended semen can be stored at low temperatures to slow bacterial growth. However, boar semen performs poorly at temperatures below 15 °C and this poses unique challenges, as it is not easy to maintain a constant 15-19 °C during shipment. Some extenders have been formulated with egg yolk for storage ...

journal_title：Systems biology in reproductive medicine

authors： Casas I,Miller-Lux Y,Osborne B,Bonet S,Althouse GC

更新日期：2015-01-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF), a major angiogenic factor, is known to play an important role in the development of endometriosis. The aim of this study was to investigate the association of three VEGF (-460 C/T, +405 G/C, and +936 C/T) polymorphisms with the risk of endometriosis in the Tunisian popula...

journal_title：Systems biology in reproductive medicine

authors： Henidi B,Kaabachi W,Naouali A,Kaabachi S,Zhioua A,Haj Sassi F,Hamzaoui K

更新日期：2015-01-01 00:00:00

abstract：:Reproductive biology is considered a specialty field, however, an argument can be made that it is instead generally applicable to many fields of biology. The one-cell embryo is presented here as a model system for the study of eukaryotic DNA replication, apoptotic DNA degradation, and signaling mechanisms between the ...

journal_title：Systems biology in reproductive medicine

authors： Ortega MA,Sil P,Ward WS

更新日期：2011-02-01 00:00:00

abstract：:Maternal obesity can cause complications for both women and their offspring for generations. Therefore, we intended to verify the repercussions of induction of transgenerational obesity on biochemical parameters, reproductive performance, and congenital anomaly frequency in Wistar rats. Female rats were used from succ...

journal_title：Systems biology in reproductive medicine

authors： Soares TS,Andreolla AP,Miranda CA,Klöppel E,Rodrigues LS,Moraes-Souza RQ,Damasceno DC,Volpato GT,Campos KE

更新日期：2018-02-01 00:00:00

abstract：:To date we have yet to examine whether amino acid (AA) transport in human ovarian follicles is affected by competitive inhibition. In contrast, transplacental transfer of AAs in late-gestation sheep is characterized by reciprocal competition. This phenomenon has been described by algebraic equations of umbilical uptak...

journal_title：Systems biology in reproductive medicine

authors： Jóźwik M,Jóźwik M,Milewska AJ,Battaglia FC,Jóźwik M

更新日期：2017-10-01 00:00:00

abstract：:Multiple prevention therapy has gained importance for the prevention and treatment of sexually transmitted diseases, especially HIV/AIDS. Antiretroviral drugs encapsulated in nanoparticles have been developed for efficient delivery of the drugs to the vaginal surface. Lactoferrin nanoparticles (LFNPs) encapsulating an...

journal_title：Systems biology in reproductive medicine

authors： Madugulla L,Ravula AR,Kondapi AK,Yenugu S

更新日期：2019-06-01 00:00:00

abstract：:During spermatogenesis, changes in sperm nuclear morphology are associated with the replacement of core somatic histones by protamines. Although protamines are the major nucleoproteins of mature sperm, not all species totally replace the histones. Histone H1, along with protamines, mediates chromatin condensation into...

journal_title：Systems biology in reproductive medicine

authors： Sánchez-Vázquez ML,Flores-Alonso JC,Merchant-Larios H,Reyes R

更新日期：2008-11-01 00:00:00

abstract：:The ICSI procedure was invented to treat severe male infertility but is often used even if the sperm quality parameters are normal. This practice has recently been called into question, but there is still no clear answer especially in terms of sperm morphology, regarding when it is necessary to perform ICSI and when c...

journal_title：Systems biology in reproductive medicine

authors： Stimpfel M,Jancar N,Vrtacnik-Bokal E,Virant-Klun I

更新日期：2019-12-01 00:00:00

abstract：:Pulsatile secretion of hormones in the hypothalamic-pituitary-gonadal axis is critical for normal functioning of the reproductive system. Thus, appropriate characterization of pulsatile secretion is important for identifying the (patho)physiology of reproductive conditions. Existing analysis methods often fail to adeq...

journal_title：Systems biology in reproductive medicine

authors： Liu H,Polotsky AJ,Grunwald GK,Carlson NE

更新日期：2018-02-01 00:00:00

abstract：:For patients with recurrent implantation failure in IVF, histologic or transcriptomic testing of the endometrium during the mid-secretory phase is often considered. Histological dating of endometrial biopsies (Noyes criteria) can determine if endometrial morphology is consistent with the period of receptivity. Alterna...

journal_title：Systems biology in reproductive medicine

authors： Cohen AM,Ye XY,Colgan TJ,Greenblatt EM,Chan C

更新日期：2020-12-01 00:00:00

abstract：:Assisted reproductive technology has evolved tremendously since the emergence of in vitro fertilization (IVF). In the course of the recent decade, there have been significant efforts in order to minimize multiple gestations, while improving percentages of singleton pregnancies and offering individualized services in I...

journal_title：Systems biology in reproductive medicine

authors： Simopoulou M,Sfakianoudis K,Antoniou N,Maziotis E,Rapani A,Bakas P,Anifandis G,Kalampokas T,Bolaris S,Pantou A,Pantos K,Koutsilieris M

更新日期：2018-10-01 00:00:00

abstract：:Increased trophoblast apoptosis has been implicated in pregnancies complicated by fetal growth restriction and preeclampsia (EC). We investigated placenta growth factor (PLGF) signaling during trophoblast apoptosis in culture and X-linked inhibitor of apoptosis protein (XIAP) and apoptosis inducible factor (AIF) in th...

journal_title：Systems biology in reproductive medicine

authors： Arroyo J,Price M,Straszewski-Chavez S,Torry RJ,Mor G,Torry DS

更新日期：2014-10-01 00:00:00

abstract：:There are variant rates of oocyte degeneration after intracytoplasmic sperm injection (ICSI) among different patients. Oocyte degeneration after ICSI may reflect the cohort of oocyte quality and subsequent embryo development capacity and clinical outcome. This retrospective study analyzed 255 cycles with at least one ...

journal_title：Systems biology in reproductive medicine

authors： Liu L,Cai J,Li P,Jiang X,Ren J

更新日期：2017-04-01 00:00:00

abstract：:Complete deletions in the AZF (a, b, and c) sub-regions of the Y-chromosome have been shown to contribute to unexplained male infertility. However, the role of partial AZFc deletions in male infertility remains to be verified. Three types of partial AZFc deletions have been identified. They are gr/gr, b1/b3, and b2/b3...

journal_title：Systems biology in reproductive medicine

authors： Almeamar HA,Ramachandran V,Ismail P,Nadkarni P,Fawzi N

更新日期：2013-04-01 00:00:00

abstract：:In order to identify unreliable data in a dataset of motility parameters obtained from a pilot study acquired by a veterinarian with experience in boar semen handling, but without experience in the operation of a computer assisted sperm analysis (CASA) system, a multivariate graphical and statistical analysis was perf...

journal_title：Systems biology in reproductive medicine

authors： Martínez LB,Crispín RH,Mendoza MM,Gallegos OH,Martínez AA

更新日期：2013-06-01 00:00:00

abstract：:Spermatozoa contain a complex population of RNAs including messenger RNAs (mRNAs) and small RNAs such as microRNAs (miRNA). It has been reported that these RNAs can be used to understand the mechanisms by which toxicological exposure affects spermatogenesis. The aim of our study was to compare mRNA and miRNA profiles ...

journal_title：Systems biology in reproductive medicine

authors： Metzler-Guillemain C,Victorero G,Lepoivre C,Bergon A,Yammine M,Perrin J,Sari-Minodier I,Boulanger N,Rihet P,Nguyen C

更新日期：2015-06-01 00:00:00