Acute severe aortic regurgitation. Pathophysiology, clinical recognition, and management.

abstract：:Because the cholesterol-rich very low density (VLD) lipoproteins of subjects with type III hyperlipoproteinemia are distinctively enriched in apolipoprotein E, a radial immunodiffusion assay for apolipoprotein E in whole plasma was developed. Its diagnostic usefulness was tested in randomly selected (n = 174) and hype...

journal_title：Annals of internal medicine

authors： Kushwaha RS,Hazzard WR,Wahl PW,Hoover JJ

更新日期：1977-11-01 00:00:00

abstract：:Considerable evidence links elevated blood cholesterol levels to the development of atherosclerosis. The National Cholesterol Education Program (NCEP) has recently published revised guidelines for detecting and treating hypercholesterolemia in adults. Included in these guidelines is the recommendation that all adults ...

journal_title：Annals of internal medicine

authors： LaRosa JC

更新日期：1996-03-01 00:00:00

abstract：:Electrophysiologic studies were done in 32 patients with aortic stenosis. In 24 patients with intact A-V conduction, A-H intervals ranged from 55 to 145 msec and were prolonged in two. Two had split His bundle potentials. The H-V intervals ranged from 25 to 94 msec and were prolonged in 12. The mean H-V interval was 6...

journal_title：Annals of internal medicine

authors： Dhingra RC,Amat-y-Leon F,Pietras RJ,Wyndham C,Deedwania PC,Wu D,Denes P,Rosen KM

更新日期：1977-09-01 00:00:00

abstract：:Smoking remains the leading cause of preventable death in the United States, yet it is still regarded by many as merely a bad habit. Most smokers want to quit but find it difficult. Behavioral counseling and pharmacotherapies are available, safe, and effective in the treatment of tobacco dependence. Nicotine replaceme...

journal_title：Annals of internal medicine

authors： Steinberg MB,Schmelzer AC,Richardson DL,Foulds J

更新日期：2008-04-01 00:00:00

abstract：:Position statements opposing legalization of physician-assisted suicide by organizations such as the American College of Physicians-American Society of Internal Medicine rightly emphasize that palliative care should be the standard of care for the dying, and that the inadequacies that exist in its delivery should be r...

journal_title：Annals of internal medicine

authors： Quill TE,Cassel CK

更新日期：2003-02-04 00:00:00

abstract：:Disseminated candidiasis has become an important infection, particularly in immunocompromised and postoperative patients. Although serologic tests may, in some settings, facilitate a premortem diagnosis, the disease is usually diagnosed by comprehensive clinical evaluation. Detection of the relatively newly recognized...

journal_title：Annals of internal medicine

authors： Edwards JE Jr,Lehrer RI,Stiehm ER,Fischer TJ,Young LS

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain. PURPOSE:To identify particular exercise intervention characteristics that decrease pain and improve function in adults with nonspecific ...

journal_title：Annals of internal medicine

authors： Hayden JA,van Tulder MW,Tomlinson G

更新日期：2005-05-03 00:00:00

abstract：Background:Zika virus has spread rapidly in the Americas and has been imported into many nonendemic countries by travelers. Objective:To describe clinical manifestations and epidemiology of Zika virus disease in travelers exposed in the Americas. Design:Descriptive, using GeoSentinel records. Setting:63 travel and t...

journal_title：Annals of internal medicine

authors： Hamer DH,Barbre KA,Chen LH,Grobusch MP,Schlagenhauf P,Goorhuis A,van Genderen PJ,Molina I,Asgeirsson H,Kozarsky PE,Caumes E,Hagmann SH,Mockenhaupt FP,Eperon G,Barnett ED,Bottieau E,Boggild AK,Gautret P,Hynes NA,Kuhn

更新日期：2017-01-17 00:00:00

abstract：:We report a case of combined idiopathic immune neutropenia and immune thrombocytopenia (thromboneutropenia). Therapy with prednisone was ineffective. Treatment with vincristine raised the patient's platelet count but did not increase the neutrophil count. Splenectomy led to a prompt complete remission. Using radioimmu...

journal_title：Annals of internal medicine

authors： Linker CA,Newcom SR,Nilsson CM,Wolf JL,Shuman MA

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Physical activity has been related to enhanced bone mass and improved physical functioning and thus may reduce the risk for osteoporotic fracture. OBJECTIVE:To determine whether higher levels of physical activity are related to lower incidence of hip, wrist, and vertebral fractures. DESIGN:Prospective coho...

journal_title：Annals of internal medicine

authors： Gregg EW,Cauley JA,Seeley DG,Ensrud KE,Bauer DC

更新日期：1998-07-15 00:00:00

abstract：:Sera of 24 patients with an unexplained pneumonia were tested for the presence of antibodies against the Legionnaires' disease bacterium. Fifteen patients had positive serology. The series comprised 12 male and three female patients ranging in age from 17 to 66 years (mean, 51.1 years). All of the patients had a high ...

journal_title：Annals of internal medicine

authors： Meenhorst PL,van der Meer JW,Borst J

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Early prenatal care is vital for improving maternal health outcomes and health behaviors, but medically vulnerable and underserved populations are less likely to begin prenatal care in the first trimester. In 2017, the Health Center Program provided safety-net care to more than 27 million persons, including ...

journal_title：Annals of internal medicine

authors： Robbins C,Martocci S

更新日期：2020-12-01 00:00:00

abstract：SOURCE CITATION:Tsapas A, Avgerinos I, Karagiannis T, et al. Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: a systematic review and network meta-analysis. Ann Intern Med. 2020;173:278-86. 32598218. ...

journal_title：Annals of internal medicine

authors： Gandhi GY

更新日期：2020-11-17 00:00:00

abstract：OBJECTIVE:To examine, from the perspective of primary care physicians, the value of mental status findings and ancillary tests in diagnosing dementia or its causes. DATA SOURCES:Studies identified using MEDLINE and bibliographies of pertinent articles. STUDY SELECTION:Selection based on availability of information on...

journal_title：Annals of internal medicine

authors： Siu AL

更新日期：1991-07-15 00:00:00

abstract：:The usefulness of HbA, as a monitor of metabolic control was studied in 15 diabetic outpatients during periods of stable, deteriorating, and improving control. Mean fasting concentrations of HbA, and plasma glucose during a 3-month period of stable control were 12.6% +/- 0.8% and 120 +/- 8 mg/dL, respectively. One wee...

journal_title：Annals of internal medicine

authors： Boden G,Master RW,Gordon SS,Shuman CR,Owen OE

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Primary aldosteronism is a common cause of treatment-resistant hypertension. However, evidence from local health systems suggests low rates of testing for primary aldosteronism. OBJECTIVE:To evaluate testing rates for primary aldosteronism and evidence-based hypertension management in patients with treatmen...

journal_title：Annals of internal medicine

authors： Cohen JB,Cohen DL,Herman DS,Leppert JT,Byrd JB,Bhalla V

更新日期：2020-12-29 00:00:00

abstract：SOURCE CITATION:Mahady SE, Margolis KL, Chan A, et al. Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial. Gut. 2020. [Epub ahead of print.] 32747412. ...

journal_title：Annals of internal medicine

authors： Hirsch C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Exercise stress testing in patients with abdominal aortic aneurysms may cause enlargement or rupture of aneurysms. OBJECTIVE:To evaluate the safety of treadmill exercise stress testing in patients with abdominal aortic aneurysms. DESIGN:Retrospective descriptive study. SETTING:Tertiary care center. PATIE...

journal_title：Annals of internal medicine

authors： Best PJ,Tajik AJ,Gibbons RJ,Pellikka PA

更新日期：1998-10-15 00:00:00

abstract：:In the 5 years since its release for clinical use, acyclovir (9-[2-hydroxyethoxymethyl]guanine) has proved to be a safe and effective agent for therapy of herpes simplex and varicella-zoster infections. The drug's availability in topical, oral, and intravenous preparations has allowed its use in a range of clinical si...

journal_title：Annals of internal medicine

authors： Dorsky DI,Crumpacker CS

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:To determine the number and distribution of internists in subspecialty training and compare with data collected since 1976; to determine the distribution of activity of subspecialty fellows; and to focus on hematology and oncology. DESIGN:Repeated mail survey with telephone follow-up. PARTICIPANTS:All direc...

journal_title：Annals of internal medicine

authors： Lyttle CS,Andersen RM,Neymarc K,Schmidt C,Kohrman CH,Levey GS

更新日期：1991-01-01 00:00:00

abstract：:Many investigations consider the presence of e antigen (HBeAg) valuable in predicting which patients with acute hepatitis B are at risk of remaining infected and developing chronic liver disease. We tested this hypothesis in a retrospective study of serial samples from patients undergoing long-term hemodialysis. We fo...

journal_title：Annals of internal medicine

authors： Werner BG,Blumberg BS

更新日期：1978-09-01 00:00:00

abstract：:Levels of circulating platelet aggregates and plasma beta-thromboglobulin reflect the degree of platelet activation in vascular injury and repair. Both values were evaluated in 38 patients with scleroderma and 18 control subjects matched for age, sex, and race. Circulating platelet aggregates (expressed as percentage ...

journal_title：Annals of internal medicine

authors： Kahaleh MB,Osborn I,Leroy EC

更新日期：1982-05-01 00:00:00

abstract：Background:Cardiovascular implantable electronic devices (CIEDs) are associated with procedure-related complications, yet little is known about variation in complication rates among institutions that may suggest disparities in care quality. Objective:To assess institutional variation in risk-standardized complication ...

journal_title：Annals of internal medicine

authors： Ranasinghe I,Labrosciano C,Horton D,Ganesan A,Curtis JP,Krumholz HM,McGavigan A,Hossain S,Air T,Hariharaputhiran S

更新日期：2019-09-03 00:00:00

abstract：:The past 2 decades have seen a revolution in legal access to cannabis, driven largely by activists and business interests. As a result, the population of cannabis users nationwide-especially daily users-has grown significantly. An estimated 4.5-7 million persons in the United States now meet criteria for cannabis use ...

journal_title：Annals of internal medicine

authors： Williams AR,Hill KP

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Data suggest that the effects of coronavirus disease 2019 (COVID-19) differ among U.S. racial/ethnic groups. PURPOSE:To evaluate racial/ethnic disparities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates and COVID-19 outcomes, factors contributing to disparities, and intervent...

journal_title：Annals of internal medicine

authors： Mackey K,Ayers CK,Kondo KK,Saha S,Advani SM,Young S,Spencer H,Rusek M,Anderson J,Veazie S,Smith M,Kansagara D

更新日期：2020-12-01 00:00:00

abstract：:Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation sugges...

journal_title：Annals of internal medicine

authors： Kitahara M,Cosgriff TM,Eyre HJ

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE:To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to ...

journal_title：Annals of internal medicine

authors： Petersen LA,Simpson K,Sorelle R,Urech T,Chitwood SS

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Because psychological approaches are likely to produce sustained benefits without the risk for tolerance or adverse effects associated with pharmacologic approaches, cognitive behavioral therapy for insomnia (CBT-i) is now commonly recommended as first-line treatment for chronic insomnia. PURPOSE:To determi...

journal_title：Annals of internal medicine

authors： Trauer JM,Qian MY,Doyle JS,Rajaratnam SM,Cunnington D

更新日期：2015-08-04 00:00:00

abstract：SOURCE CITATION:Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in patients with chronic coronary disease. N Engl J Med. 2020;383:1838-47. 32865380. ...

journal_title：Annals of internal medicine

authors： Cohn JN

更新日期：2021-01-01 00:00:00

abstract：:Severe pulmonary hypertension without pulmonary fibrosis occurred in 10 patients with the CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia), reputedly a benign variant of progressive systemic sclerosis. Time from the initial symptom, Raynaud's phenomenon, to the r...

journal_title：Annals of internal medicine

authors： Salerni R,Rodnan GP,Leon DF,Shaver JA

更新日期：1977-04-01 00:00:00