Cholesterol agonistics.

abstract：BACKGROUND:Depressive disorders are persistent, recurring illnesses that cause great suffering for patients and their families. PURPOSE:To evaluate the benefits and adverse effects of newer pharmacotherapies and herbal treatments for depressive disorders in adults and adolescents. DATA SOURCES:English-language and no...

journal_title：Annals of internal medicine

authors： Williams JW Jr,Mulrow CD,Chiquette E,Noël PH,Aguilar C,Cornell J

更新日期：2000-05-02 00:00:00

abstract：:Patients with serious psychiatric disorders are frequently treated by primary care physicians, who may have difficulty keeping up with recent advances in psychiatry. This paper presents an updated synopsis for three major psychiatric illnesses: major depression, bipolar disorder, and schizophrenia. Current definitions...

journal_title：Annals of internal medicine

authors： Glick ID,Suppes T,DeBattista C,Hu RJ,Marder S

更新日期：2001-01-02 00:00:00

abstract：DESCRIPTION:Update of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for breast cancer. METHODS:The USPSTF reviewed the evidence on the following: effectiveness of breast cancer screening in reducing breast cancer-specific and all-cause mortality, as well as the incidence of advanced...

journal_title：Annals of internal medicine

authors： Siu AL,U.S. Preventive Services Task Force.

更新日期：2016-02-16 00:00:00

abstract：DESCRIPTION:This guideline is an official statement of the American College of Physicians (ACP), American College of Chest Physicians (ACCP), American Thoracic Society (ATS), and European Respiratory Society (ERS). It represents an update of the 2007 ACP clinical practice guideline on diagnosis and management of stable...

journal_title：Annals of internal medicine

authors： Qaseem A,Wilt TJ,Weinberger SE,Hanania NA,Criner G,van der Molen T,Marciniuk DD,Denberg T,Schünemann H,Wedzicha W,MacDonald R,Shekelle P,American College of Physicians.,American College of Chest Physicians.,American Thoracic

更新日期：2011-08-02 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha is present in arteries in giant cell arteritis. OBJECTIVE:To evaluate the efficacy of infliximab, an anti-tumor necrosis factor-alpha agent, in giant cell arteritis. DESIGN:Randomized, controlled trial. SETTING:22 sites in the United States, the United Kingdom, Belgium, Italy, ...

journal_title：Annals of internal medicine

authors： Hoffman GS,Cid MC,Rendt-Zagar KE,Merkel PA,Weyand CM,Stone JH,Salvarani C,Xu W,Visvanathan S,Rahman MU,Infliximab-GCA Study Group.

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To assess the accuracy of Histoplasma capsulatum variety capsulatum polysaccharide antigen testing for the identification of histoplasmosis relapse in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN:A retrospective study using stored specimens. SETTING:A referral center and several priva...

journal_title：Annals of internal medicine

authors： Wheat LJ,Connolly-Stringfield P,Blair R,Connolly K,Garringer T,Katz BP

更新日期：1991-12-15 00:00:00

abstract：BACKGROUND:Questions remain about the importance of smoking and smoking cessation after incident myocardial infarction. OBJECTIVE:To assess the association between smoking status and risk for recurrent coronary events. DESIGN:Retrospective, population-based, inception cohort study. SETTING:Health maintenance organiz...

journal_title：Annals of internal medicine

authors： Rea TD,Heckbert SR,Kaplan RC,Smith NL,Lemaitre RN,Psaty BM

更新日期：2002-09-17 00:00:00

abstract：:The coexistence of pregnancy and idiopathic hypertrophic subaortic stenosis is a potentially dangerous combination. We report a 23-year-old white woman with idiopathic hypertrophic subaortic stenosis and pregnancy who presented with severe symptoms (Class IV) and modest outflow obstruction associated with marked mitra...

journal_title：Annals of internal medicine

authors： Kolibash AJ,Ruiz DE,Lewis RP

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells can differentiate into endothelial cells and participate in angiogenesis in adults. In experimental models of acute myocardial infarction, mesenchymal stem cells led to the recovery of cardiac function through the formation of a new vascular network. OBJECTIVE:To describe treatment wi...

journal_title：Annals of internal medicine

authors： Guiducci S,Porta F,Saccardi R,Guidi S,Ibba-Manneschi L,Manetti M,Mazzanti B,Dal Pozzo S,Milia AF,Bellando-Randone S,Miniati I,Fiori G,Fontana R,Amanzi L,Braschi F,Bosi A,Matucci-Cerinic M

更新日期：2010-11-16 00:00:00

abstract：:Active-control noninferiority trials are being performed with increasing frequency when standard placebo-controlled trials are considered unethical. Three attributes are optimally required to establish noninferiority: 1) The treatment under consideration exhibits therapeutic noninferiority to the active control; 2) th...

journal_title：Annals of internal medicine

authors： Kaul S,Diamond GA

更新日期：2006-07-04 00:00:00

abstract：:Four hemodialysis patients receiving deferoxamine for metal overload had fatal rhinocerebral rhizopus infections. Serious fungal infections are not commonly seen in patients on dialysis, and none of these patients had the usual risk factors for rhizopus infection. Deferoxamine is being used with increased frequency in...

journal_title：Annals of internal medicine

authors： Windus DW,Stokes TJ,Julian BA,Fenves AZ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:The vast scientific literature on smoking and health contains few large studies with direct estimates of long-term mortality by smoking habits. Data have been lacking, particularly for women. OBJECTIVE:To study smoking and deaths and causes of death in women and men of middle age (40 to 70 years of age). D...

journal_title：Annals of internal medicine

authors： Vollset SE,Tverdal A,Gjessing HK

更新日期：2006-03-21 00:00:00

abstract：BACKGROUND:With suspected deep venous thrombosis and normal results on proximal vein ultrasonography, a negative d-dimer result may exclude thrombosis and a positive D-dimer result may be an indication for venography. OBJECTIVE:To evaluate and compare the safety of 2 diagnostic strategies for deep venous thrombosis. ...

journal_title：Annals of internal medicine

authors： Kearon C,Ginsberg JS,Douketis J,Crowther MA,Turpie AG,Bates SM,Lee A,Brill-Edwards P,Finch T,Gent M

更新日期：2005-04-05 00:00:00

abstract：:Abdominal aortic aneurysms (AAAs) occur in 1 of 20 older men, remain asymptomatic for many years, and, if left untreated, cause death from rupture in about one third of patients. Ultrasonography is a suitable screening test for AAA, and elective repair can prevent rupture. Although these features suggest a promising t...

journal_title：Annals of internal medicine

authors： Lederle FA

更新日期：2003-09-16 00:00:00

abstract：:The 1986 False Claims Act Amendments authorize private citizens to sue on behalf of the U.S. government to recover federal funds from fraudulent recipients. The "relator" receives a share of any proceeds from a successful lawsuit. Originally enacted because of defense procurement scandals, this statute also applies to...

journal_title：Annals of internal medicine

authors： Hsia DC

更新日期：1991-06-15 00:00:00

abstract：BACKGROUND:Depression collaborative care implementation using community engagement and planning (CEP) across programs improves 6-month client outcomes in minority communities, compared with technical assistance to individual programs (resources for services [RS]). However, 12-month outcomes are unknown. OBJECTIVE:To c...

journal_title：Annals of internal medicine

authors： Chung B,Ong M,Ettner SL,Jones F,Gilmore J,McCreary M,Sherbourne C,Ngo V,Koegel P,Tang L,Dixon E,Miranda J,Belin TR,Wells KB

更新日期：2014-11-18 00:00:00

abstract：STUDY OBJECTIVE:To determine the efficacy of continuous intravenous infusion of prostacyclin (epoprostenol) in primary pulmonary hypertension. DESIGN:Randomized trial with 8-week treatment periods and nonrandomized treatment for up to 18 months. SETTING:Four referral centers. PATIENTS:Sequential sample of 24 patient...

journal_title：Annals of internal medicine

authors： Rubin LJ,Mendoza J,Hood M,McGoon M,Barst R,Williams WB,Diehl JH,Crow J,Long W

更新日期：1990-04-01 00:00:00

abstract：:Ninety-six patients with life-threatening ventricular arrhythmias refractory to two or more conventional agents were treated with amiodarone and followed for 6 to 40 months (mean, 15 months). Currently, 75 are alive and well. Seven patients died from nonarrhythmic and five from arrhythmic causes. Nonfatal arrhythmias ...

journal_title：Annals of internal medicine

authors： Nademanee K,Singh BN,Hendrickson J,Intarachot V,Lopez B,Feld G,Cannom DS,Weiss JL

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Lateral epicondylitis is a common condition for which botulinum toxin has been reported to have a therapeutic role in uncontrolled studies. OBJECTIVE:To determine if an injection of botulinum toxin is more effective than placebo for reducing pain in adults with lateral epicondylitis. DESIGN:Randomized, dou...

journal_title：Annals of internal medicine

authors： Wong SM,Hui AC,Tong PY,Poon DW,Yu E,Wong LK

更新日期：2005-12-06 00:00:00

abstract：:The diagnostic and therapeutic value of the angiotensin converting enzyme inhibitor teprotide (SQ 20881) was assessed in 18 patients with hypertensive emergencies. Mean blood pressure fell 31 +/- 18 mm Hg in the 10 subjects who responded to 1 mg/kg body weight administered intravenously, whereas it fell 5 +/- 3 mm Hg ...

journal_title：Annals of internal medicine

authors： Tifft CP,Gavras H,Kershaw GR,Gavras I,Brunner HR,Liang CS,Chobanian AV

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Few treatments exist for coronavirus disease 2019 (COVID-19). PURPOSE:To evaluate the effectiveness and harms of remdesivir for COVID-19. DATA SOURCES:Several databases, tables of contents of journals, and U.S. Food and Drug Administration and company websites were searched from 1 January through 31 August...

journal_title：Annals of internal medicine

authors： Wilt TJ,Kaka AS,MacDonald R,Greer N,Obley A,Duan-Porter W

更新日期：2020-10-05 00:00:00

abstract：:Simulation is a versatile technique used in a variety of health care settings for a variety of purposes, but the extent to which simulation may improve patient safety remains unknown. This systematic review examined evidence on the effects of simulation techniques on patient safety outcomes. PubMed and the Cochrane Li...

journal_title：Annals of internal medicine

authors： Schmidt E,Goldhaber-Fiebert SN,Ho LA,McDonald KM

更新日期：2013-03-05 00:00:00

abstract：:Systematic reviewers increasingly must decide whether and how to incorporate existing systematic reviews into complex systematic reviews that are commissioned to support clinical guideline development or for other health policy uses. To date, however, this issue has been largely unexamined. Reviewers seeking to incorp...

journal_title：Annals of internal medicine

authors： Whitlock EP,Lin JS,Chou R,Shekelle P,Robinson KA

更新日期：2008-05-20 00:00:00

abstract：:A 17-year-old girl with a clinical diagnosis of adult-type juvenile rheumatoid arthritis developed a severe hepatotoxic reaction to 3.6 g of aspirin per day. This was associated with a microangiopathic anemia and transient congestive cardiac failure. She responded well to steroids, and when all laboratory test finding...

journal_title：Annals of internal medicine

authors： Sbarbaro JA,Bennett RM

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain. PURPOSE:To identify particular exercise intervention characteristics that decrease pain and improve function in adults with nonspecific ...

journal_title：Annals of internal medicine

authors： Hayden JA,van Tulder MW,Tomlinson G

更新日期：2005-05-03 00:00:00

abstract：:Neuropathologic and neurochemical studies of older adults with Down's syndrome and those with Alzheimer's disease reveal striking similarities. Genetic studies indicate that near relatives of patients with Alzheimer's disease are at increased risk of developing Alzheimer's disease, and the risk appears to be age speci...

journal_title：Annals of internal medicine

authors： Cutler NR,Heston LL,Davies P,Haxby JV,Schapiro MB

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Studies suggest that vitamin D supplementation may reduce cancer and fracture risks. PURPOSE:To examine the benefits and harms of vitamin D with or without calcium supplementation on clinical outcomes of cancer and fractures in adults. DATA SOURCES:English-language studies identified from MEDLINE and the C...

journal_title：Annals of internal medicine

authors： Chung M,Lee J,Terasawa T,Lau J,Trikalinos TA

更新日期：2011-12-20 00:00:00

abstract：:Sudden cardiac death remains a leading cause of death in the United States, accounting for more than 350,000 deaths each year, and the survival rate of victims remains low. Most survivors face a significant risk for recurrence. The typical substrate is chronic--abnormal myocardium with fibrosis (often from previous my...

journal_title：Annals of internal medicine

authors： Akhtar M,Garan H,Lehmann MH,Troup PJ

更新日期：1991-03-15 00:00:00

abstract：:It is well recognized that physicians' relationships with their patients can have healing effects, but the skills in this area of medical practice are understudied. This article reports on research designed to identify a core set of healing skills. The authors interviewed 50 practitioners, who were identified by their...

journal_title：Annals of internal medicine

authors： Churchill LR,Schenck D

更新日期：2008-11-18 00:00:00

abstract：BACKGROUND:Bed alarm systems intended to prevent hospital falls have not been formally evaluated. OBJECTIVE:To investigate whether an intervention aimed at increasing bed alarm use decreases hospital falls and related events. DESIGN:Pair-matched, cluster randomized trial over 18 months. Nursing units were allocated b...

journal_title：Annals of internal medicine

authors： Shorr RI,Chandler AM,Mion LC,Waters TM,Liu M,Daniels MJ,Kessler LA,Miller ST

更新日期：2012-11-20 00:00:00