NIH Conference. Alzheimer's disease and Down's syndrome: new insights.

abstract：BACKGROUND:Urine tests for Chlamydia trachomatis permit expansion of screening beyond traditional clinic environments. Prevention of infection in teenagers is a high priority. OBJECTIVE:To define the prevalence of C. trachomatis among teenagers by using the ligase chain reaction assay on urine specimens and to evaluat...

journal_title：Annals of internal medicine

authors： Marrazzo JM,White CL,Krekeler B,Celum CL,Lafferty WE,Stamm WE,Handsfield HH

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:To evaluate the possibility that fibrinogen represents a cardiovascular risk factor. DATA IDENTIFICATION:A computerized literature search (1980 to 1992) identified all published epidemiologic studies on fibrinogen and cardiovascular disease. Clinical and basic research data were found by separate searches. Ref...

journal_title：Annals of internal medicine

authors： Ernst E,Resch KL

更新日期：1993-06-15 00:00:00

abstract：Background:Patients desire information about health care costs because they are increasingly responsible for these costs. Public Web sites that offer cost information could inform provider-patient discussions of costs at the point of care. Objective:To evaluate tools to facilitate the use of publicly available cost in...

journal_title：Annals of internal medicine

authors： Fox KS,Gray CE,Williamson ME,MacKenzie JA

更新日期：2019-05-07 00:00:00

abstract：:Ten patients with lupus nephritis and marked proteinuria (3.9 g or more/d) that did not respond adequately to treatment with prednisone alone or prednisone in combination with azathioprine were treated with total lymphoid irradiation in an uncontrolled feasibility study. Within 6 weeks after the start of total lymphoi...

journal_title：Annals of internal medicine

authors： Strober S,Field E,Hoppe RT,Kotzin BL,Shemesh O,Engleman E,Ross JC,Myers BD

更新日期：1985-04-01 00:00:00

abstract：PURPOSE:To synthesize new data on breast cancer screening for the U.S. Preventive Services Task Force. DATA SOURCES:MEDLINE; the Cochrane Controlled Trials Registry; and reference lists of reviews, editorials, and original studies. STUDY SELECTION:Eight randomized, controlled trials of mammography and 2 trials evalua...

journal_title：Annals of internal medicine

authors： Humphrey LL,Helfand M,Chan BK,Woolf SH

更新日期：2002-09-03 00:00:00

abstract：:Patients with variant angina refractory to medical therapy pose a difficult management problem. We report two patients with variant angina who had focal spasm in coronary arteries with fixed obstructions of less than 20% of the luminal diameter. Ischemic episodes were accompanied by malignant ventricular arrhythmias a...

journal_title：Annals of internal medicine

authors： Sussman EJ,Goldberg S,Poll DS,MacVaugh H 3rd,Simson MB,Silber SA,Kastor JA

更新日期：1981-06-01 00:00:00

abstract：:A model of activation, proliferation, and differentiation of human lymphocyte responses is described, and the complex immunoregulatory modulation of this system discussed with regard to normal immune function and the aberrancies expressed in diseases characterized by abnormalities of immune function. Recent advances i...

journal_title：Annals of internal medicine

authors： Fauci AS,Lane HC,Volkman DJ

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Progress of diabetes care is a subject of public health concern. OBJECTIVE:To assess changes in quality of diabetes care in the United States by using standardized measures. DESIGN:National population-based, serial cross-sectional surveys. SETTING:National Health and Nutrition Examination Survey (1988-199...

journal_title：Annals of internal medicine

authors： Saaddine JB,Cadwell B,Gregg EW,Engelgau MM,Vinicor F,Imperatore G,Narayan KM

更新日期：2006-04-04 00:00:00

abstract：OBJECTIVE:To describe 13 infections caused by Mycobacterium haemophilum. DESIGN:Identification of patients by microbiologic record review, followed by medical record review and a case-control study. SETTING:Seven metropolitan hospitals in New York. PATIENTS:All patients with M. haemophilum infections diagnosed betwe...

journal_title：Annals of internal medicine

authors： Straus WL,Ostroff SM,Jernigan DB,Kiehn TE,Sordillo EM,Armstrong D,Boone N,Schneider N,Kilburn JO,Silcox VA,LaBombardi V,Good RC

更新日期：1994-01-15 00:00:00

abstract：Background:FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. Objective:To compare the safety, immunogenicity, and exploratory efficacy of different formulations and dosing regimens of FLU-v versus placebo. Design:Randomized, double-blind, placebo-controlled, single-center...

journal_title：Annals of internal medicine

authors： Pleguezuelos O,Dille J,de Groen S,Oftung F,Niesters HGM,Islam MA,Næss LM,Hungnes O,Aldarij N,Idema DL,Perez AF,James E,Frijlink HW,Stoloff G,Groeneveld P,Hak E

更新日期：2020-04-07 00:00:00

abstract：:Although many manifestations of giant cell arteries are increasingly recognized, little attention has been paid to respiratory symptoms associated with this disorder. We report the cases of 16 patients with giant cell arteritis who had prominent symptoms related to the respiratory tract including cough, sore throat, a...

journal_title：Annals of internal medicine

authors： Larson TS,Hall S,Hepper NG,Hunder GG

更新日期：1984-11-01 00:00:00

abstract：:The syndrome of bulimia is a common disorder and can be associated with serious psychological and physical morbidity. Unfortunately, many patients are reluctant to discuss their symptoms with their physicians and few clues can be found on physical examination to aid in the diagnosis. Possible physical signs include ul...

journal_title：Annals of internal medicine

authors： Mitchell JE,Seim HC,Colon E,Pomeroy C

更新日期：1987-07-01 00:00:00

abstract：:In an effort to prevent cytomegalovirus infection among seronegative patients having marrow transplants, a globulin with high antibody levels against cytomegalovirus was given before and for 11 weeks after transplantation in a randomized trial. Among 36 patients who received no prophylactic granulocyte transfusions, g...

journal_title：Annals of internal medicine

authors： Meyers JD,Leszczynski J,Zaia JA,Flournoy N,Newton B,Snydman DR,Wright GG,Levin MJ,Thomas ED

更新日期：1983-04-01 00:00:00

abstract：:For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

journal_title：Annals of internal medicine

authors： Falk RH,Leavitt JI

更新日期：1991-04-01 00:00:00

abstract：:Two cases of patients having calcification within the sella turcica (pituitary stones) have been studied and followed up, one patient for 18 years. A detailed analysis of the radiographic findings and endocrinologic profiles of these two patients is presented. The rarity of bona fide pituitary stones and their benign ...

journal_title：Annals of internal medicine

authors： Di Chiro G,Saldino R,McGuffin WL Jr,Sachson RA,Gorden P,Bartter FC

更新日期：1975-07-01 00:00:00

abstract：:A 34-year-old man had polar extremes of B cell dysfunction: systemic lupus erythematosus evolving into common variable hypogammaglobulinemia. He presented in 1974 with seizures and six other criteria for systemic lupus erythematosus; his antinuclear antibody titer was 1:1024 and IgG level, 2870 mg/dL. After 5 months o...

journal_title：Annals of internal medicine

authors： Sussman GL,Rivera VJ,Kohler PF

更新日期：1983-07-01 00:00:00

abstract：PURPOSE:It is currently unknown whether intensive insulin treatment of diabetes decreases the risk for cardiovascular complications by lowering glucose levels or increases the risk by postulated direct atherogenic effects. This article reviews published data from two long-term, randomized clinical trials that compared ...

journal_title：Annals of internal medicine

authors： Genuth S

更新日期：1996-01-01 00:00:00

abstract：:A retrospective analysis of the course of systemic lupus erythematosus in pregnant patients hospitalized at UCLA during a 15-year period provided important prognostic information. Women with systemic lupus erythematosus became pregnant if renal function was reasonably well preserved. Pregnancy infrequently posed a ser...

journal_title：Annals of internal medicine

authors：

更新日期：1981-05-01 00:00:00

abstract：DESCRIPTION:Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and othe...

journal_title：Annals of internal medicine

authors： Carson JL,Grossman BJ,Kleinman S,Tinmouth AT,Marques MB,Fung MK,Holcomb JB,Illoh O,Kaplan LJ,Katz LM,Rao SV,Roback JD,Shander A,Tobian AA,Weinstein R,Swinton McLaughlin LG,Djulbegovic B,Clinical Transfusion Medicine Com

更新日期：2012-07-03 00:00:00

abstract：BACKGROUND:Diagnosis of pulmonary embolism requires clinical probability assessment. Implicit assessment is accurate but is not standardized, and current prediction rules have shortcomings. OBJECTIVE:To construct a simple score based entirely on clinical variables and independent from physicians' implicit judgment. D...

journal_title：Annals of internal medicine

authors： Le Gal G,Righini M,Roy PM,Sanchez O,Aujesky D,Bounameaux H,Perrier A

更新日期：2006-02-07 00:00:00

abstract：PURPOSE:Cost-utility analysis is a type of cost-effectiveness analysis in which health effects are measured in terms of quality-adjusted life-years (QALYs) gained. Such analyses have become popular for examining the health and economic consequences of health and medical interventions, and they have been recommended by ...

journal_title：Annals of internal medicine

authors： Neumann PJ,Stone PW,Chapman RH,Sandberg EA,Bell CM

更新日期：2000-06-20 00:00:00

abstract：PURPOSE:To integrate information from the various disciplines that contribute to the understanding of the cause and prevention of sudden cardiac death: identification of new approaches from applied clinical epidemiology; identification and control of transient risk factors; and evaluation of the results of intervention...

journal_title：Annals of internal medicine

authors： Myerburg RJ,Kessler KM,Castellanos A

更新日期：1993-12-15 00:00:00

abstract：BACKGROUND:Because psychological approaches are likely to produce sustained benefits without the risk for tolerance or adverse effects associated with pharmacologic approaches, cognitive behavioral therapy for insomnia (CBT-i) is now commonly recommended as first-line treatment for chronic insomnia. PURPOSE:To determi...

journal_title：Annals of internal medicine

authors： Trauer JM,Qian MY,Doyle JS,Rajaratnam SM,Cunnington D

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:A sensitive and acceptable screening regimen for women at high risk for breast cancer is essential. Contrast-enhanced magnetic resonance imaging (MRI) of the breast is highly sensitive for diagnosis of breast cancer but has variable specificity. PURPOSE:To summarize the sensitivity, specificity, likelihood ...

journal_title：Annals of internal medicine

authors： Warner E,Messersmith H,Causer P,Eisen A,Shumak R,Plewes D

更新日期：2008-05-06 00:00:00

abstract：:The clinical implications of newly acquired left bundle-branch block (LBBB) were examined prospectively in the Framingham Study population. During 18 years of observation 55 people developed LBBB. The mean age at the onset of LBBB was 62; LBBB occurred largely in people with antecedent hypertension, cardiac enlargemen...

journal_title：Annals of internal medicine

authors： Schneider JF,Thomas HE Jr,Kreger BE,McNamara PM,Kannel WB

更新日期：1979-03-01 00:00:00

abstract：:Prothrombin complex concentrates are used in the treatment of the congenital bleeding disorders associated with Factors II, VII, IX, and X deficiencies. They have also been extensively used to treat acquired coagulation abnormalities secondary to vitamin K deficiency, warfarin ingestion, and various types of liver dis...

journal_title：Annals of internal medicine

authors： Cederbaum AI,Blatt PM,Roberts HR

更新日期：1976-06-01 00:00:00

abstract：:Acute severe aortic regurgitation is a relatively unfamiliar, though life-threatening, disease. We review its diverse causes, anatomic faults, and hemodynamic sequelae and set the stage for an understanding of the clinical manifestations in light of their physiologic mechanisms. Clinical information includes the natur...

journal_title：Annals of internal medicine

authors： Morganroth J,Perloff JK,Zeldis SM,Dunkman WB

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Without population-based evidence, some clinicians recommend short-term suspension of hormone therapy to improve the performance of mammography. Hormone therapy increases breast density, and abnormal screening mammograms are more common among women with denser breasts and among women using hormone therapy. ...

journal_title：Annals of internal medicine

authors： Buist DS,Anderson ML,Reed SD,Aiello Bowles EJ,Fitzgibbons ED,Gandara JC,Seger D,Newton KM

更新日期：2009-06-02 00:00:00

abstract：STUDY OBJECTIVE:To determine if the combination of ganciclovir and intravenous cytomegalovirus immunoglobulin is effective in patients with cytomegalovirus pneumonia after bone marrow transplant. DESIGN:Consecutive entry trial with treatment for a minimum of 14 days. PATIENTS:Consecutive sample of 25 patients with bo...

journal_title：Annals of internal medicine

authors： Reed EC,Bowden RA,Dandliker PS,Lilleby KE,Meyers JD

更新日期：1988-11-15 00:00:00

abstract：:The U.S. Food and Drug Administration (FDA) Amendments Act of 2007 mandated that the FDA develop a system for using automated health care data to identify risks of marketed drugs and other medical products. The Observational Medical Outcomes Partnership is a public-private partnership among the FDA, academia, data own...

journal_title：Annals of internal medicine

authors： Stang PE,Ryan PB,Racoosin JA,Overhage JM,Hartzema AG,Reich C,Welebob E,Scarnecchia T,Woodcock J

更新日期：2010-11-02 00:00:00