Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma.

abstract：STUDY OBJECTIVE:To determine the relative importance of adiposity and fat distribution to cardiovascular risk profile. DESIGN:A cross-sectional study. SETTING:Clinical research center funded by the National Institutes of Health. PATIENTS:Convenience sample of 33 healthy premenopausal women with a wide range of body ...

journal_title：Annals of internal medicine

authors： Peiris AN,Sothmann MS,Hoffmann RG,Hennes MI,Wilson CR,Gustafson AB,Kissebah AH

更新日期：1989-06-01 00:00:00

abstract：:Physical symptoms account for more than half of all outpatient visits, but the specific causes and treatments of many common symptoms are frequently not well established. Because clinical research has primarily targeted specific diseases, symptoms-based research is still an emerging field of scientific inquiry, and op...

journal_title：Annals of internal medicine

authors： Kroenke K

更新日期：2001-05-01 00:00:00

abstract：:In an era of increasing competition in medical care, critical pathway guidelines have emerged as one of the most popular new initiatives intended to reduce costs while maintaining or even improving the quality of care. Developed primarily for high-volume hospital diagnoses, critical pathways display goals for patients...

journal_title：Annals of internal medicine

authors： Pearson SD,Goulart-Fisher D,Lee TH

更新日期：1995-12-15 00:00:00

abstract：:Many health care professionals have sustained an almost single-minded conviction that disparities in access to health care across socioeconomic groups are the key reason for the major discrepancies in health status between wealthy persons and poor persons. Others, however, have argued that a host of factors work to cr...

journal_title：Annals of internal medicine

authors： Andrulis DP

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To determine whether growth hormone replacement in older men improves functional ability. DESIGN:Randomized, controlled, double-blind trial. SETTING:General community. PATIENTS:52 healthy men older than 69 years of age with well-preserved functional ability but low baseline insulin-like growth factor 1 lev...

journal_title：Annals of internal medicine

authors： Papadakis MA,Grady D,Black D,Tierney MJ,Gooding GA,Schambelan M,Grunfeld C

更新日期：1996-04-15 00:00:00

abstract：:Immediately after the liberation of Kuwait by a coalition of allied forces in March 1991, representatives of Physicians for Human Rights traveled to Kuwait and conducted an inquiry into human rights violations allegedly perpetrated by Iraqi forces. The inquiry focused on the abuses that were said to have occurred in h...

journal_title：Annals of internal medicine

authors： Brennan TA,Kirschner R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. PURPOSE:To systematically review benefits and harms of low-dose aspirin for preventing morbidity and mortality from preeclampsia. DATA SOURCES:MEDLINE, Database of Abstracts of Reviews of Effects, PubMed, and Cochrane Centra...

journal_title：Annals of internal medicine

authors： Henderson JT,Whitlock EP,O'Connor E,Senger CA,Thompson JH,Rowland MG

更新日期：2014-05-20 00:00:00

abstract：OBJECTIVE:To determine the rate of use of prophylaxis for venous thromboembolism in high-risk hospital patients. DESIGN:A retrospective medical record review. SETTING:A community-wide study in 16 short-stay hospitals in central Massachusetts. PATIENTS:A total of 2017 patients with multiple risk factors for venous th...

journal_title：Annals of internal medicine

authors： Anderson FA Jr,Wheeler HB,Goldberg RJ,Hosmer DW,Forcier A,Patwardhan NA

更新日期：1991-10-15 00:00:00

abstract：:The Federated Council for Internal Medicine (FCIM) comprises the American Board of Internal Medicine, American College of Physicians, American Society of Internal Medicine, Association of Professors of Medicine, Association of Program Directors in Internal Medicine, and the Society of General Internal Medicine. The Co...

journal_title：Annals of internal medicine

authors：

更新日期：1992-11-01 00:00:00

abstract：PURPOSE:To review the radiofrequency ablation method, describe the technique, and discuss the indications, results, and limitations of its use in patients with cardiac tachyarrhythmias. DATA SOURCES:Peer-reviewed reports in the literature by clinical investigators who use radiofrequency catheter ablation as identified...

journal_title：Annals of internal medicine

authors： Manolis AS,Wang PJ,Estes NA 3rd

更新日期：1994-09-15 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of all-trans retinoic acid to induce complete remission and to examine its effects on duration of remission and survival in patients with acute promyelocytic leukemia. DESIGN:Phase II evaluation and comparison with historical control patients. SETTING:Tertiary care cancer...

journal_title：Annals of internal medicine

authors： Frankel SR,Eardley A,Heller G,Berman E,Miller WH Jr,Dmitrovsky E,Warrell RP Jr

更新日期：1994-02-15 00:00:00

abstract：Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

journal_title：Annals of internal medicine

authors： Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

更新日期：2020-03-03 00:00:00

abstract：:Streptococcus pneumoniae causes substantial morbidity and mortality. Incidence and severity are increased among populations with some chronic diseases. The currently available polyvalent polysaccharide vaccine induces antibody production among immunologically competent recipients against the 14 serotypes responsible f...

journal_title：Annals of internal medicine

authors： Schwartz JS

更新日期：1982-02-01 00:00:00

abstract：:Because the cholesterol-rich very low density (VLD) lipoproteins of subjects with type III hyperlipoproteinemia are distinctively enriched in apolipoprotein E, a radial immunodiffusion assay for apolipoprotein E in whole plasma was developed. Its diagnostic usefulness was tested in randomly selected (n = 174) and hype...

journal_title：Annals of internal medicine

authors： Kushwaha RS,Hazzard WR,Wahl PW,Hoover JJ

更新日期：1977-11-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death among women in the United States, and stroke is third. This article uses a case scenario to examine female sex-specific cardiovascular risk factors across the lifespan and describes a precision medicine-based approach to risk factor modification and primary preventi...

journal_title：Annals of internal medicine

authors： Bello NA,Miller EC,Cleary KL,Wapner R

更新日期：2019-12-03 00:00:00

abstract：DESCRIPTION:Reaffirmation of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for testicular cancer. METHODS:The USPSTF performed a targeted literature search for benefits and harms of screening for testicular cancer in asymptomatic males and found no new studies. RECOMMENDA...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2011-04-05 00:00:00

abstract：BACKGROUND:Medicare's value-based purchasing (VBP) and the Hospital Readmissions Reduction Program (HRRP) could disproportionately affect safety-net hospitals. OBJECTIVE:To determine whether safety-net hospitals incur larger financial penalties than other hospitals under VBP and HRRP. DESIGN:Cross-sectional analysis....

journal_title：Annals of internal medicine

authors： Gilman M,Hockenberry JM,Adams EK,Milstein AS,Wilson IB,Becker ER

更新日期：2015-09-15 00:00:00

abstract：BACKGROUND:Noninvasive testing for Helicobacter pylori is widely available and has been considered as an initial management strategy for uninvestigated dyspepsia. However, data to guide clinicians in the management of patients with dyspepsia who are seropositive for H. pylori are lacking. OBJECTIVE:To examine the econ...

journal_title：Annals of internal medicine

authors： Ofman JJ,Etchason J,Fullerton S,Kahn KL,Soll AH

更新日期：1997-02-15 00:00:00

abstract：:Gentamicin and tobramycin were compared for cost effectiveness in the treatment of adult patients with serious infections in a general medical service. We used data from a randomized double-blind trial in which the only observed difference between the clinical effects of these aminoglycosides was the incidence of neph...

journal_title：Annals of internal medicine

authors： Holloway JJ,Smith CR,Moore RD,Feroli ER Jr,Lietman PS

更新日期：1984-12-01 00:00:00

abstract：:Reversible cerebral vasoconstriction syndromes (RCVS) comprise a group of diverse conditions, all characterized by reversible multifocal narrowing of the cerebral arteries heralded by sudden (thunderclap), severe headaches with or without associated neurologic deficits. Reversible cerebral vasoconstriction syndromes a...

journal_title：Annals of internal medicine

authors： Calabrese LH,Dodick DW,Schwedt TJ,Singhal AB

更新日期：2007-01-02 00:00:00

abstract：:The mechanisms of flushing reactions are pharmacologically and physiologically heterogeneous. Flushing may result from agents acting directly on the vascular smooth muscle or may be mediated by vasomotor nerves. Vasomotor nerves may lead to flushing as a result of events at both peripheral and central sites. In suscep...

journal_title：Annals of internal medicine

authors： Wilkin JK

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of housestaff physician reporting as a method for identifying adverse events on a medical service and to compare the physician reporting mechanism with a retrospective record review mechanism. SETTING:Medical service of an urban, university-affiliated teaching hospital. DESIGN:Co...

journal_title：Annals of internal medicine

authors： O'Neil AC,Petersen LA,Cook EF,Bates DW,Lee TH,Brennan TA

更新日期：1993-09-01 00:00:00

abstract：SOURCE CITATION:Tsapas A, Avgerinos I, Karagiannis T, et al. Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: a systematic review and network meta-analysis. Ann Intern Med. 2020;173:278-86. 32598218. ...

journal_title：Annals of internal medicine

authors： Gandhi GY

更新日期：2020-11-17 00:00:00

abstract：:Traditional educational methods change clinical practice only with considerable effort and difficulty. In particular, the teaching of critical appraisal in the setting of journal clubs does not increase the amount of medical research read by trainees. Experiential learning theory, corroborated by the success of proble...

journal_title：Annals of internal medicine

authors： Badgett RG,O'Keefe M,Henderson MC

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:High intake of folate may reduce risk for colon cancer, but the dosage and duration relations and the impact of dietary compared with supplementary sources are not well understood. OBJECTIVE:To evaluate the relation between folate intake and incidence of colon cancer. DESIGN:Prospective cohort study. SETT...

journal_title：Annals of internal medicine

authors： Giovannucci E,Stampfer MJ,Colditz GA,Hunter DJ,Fuchs C,Rosner BA,Speizer FE,Willett WC

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:To review epidemiologic studies on the association between homocyst(e)ine level and risk for cardiovascular disease and the potential benefits of homocysteine-decreasing therapies. DATA SOURCES:Computerized and manual searches of the literature on total homocysteine levels and cardiovascular disease. STUDY SE...

journal_title：Annals of internal medicine

authors： Eikelboom JW,Lonn E,Genest J Jr,Hankey G,Yusuf S

更新日期：1999-09-07 00:00:00

abstract：BACKGROUND:The established International Prognostic Index for lymphomas has not included patients with systemic AIDS-related non-Hodgkin lymphoma. OBJECTIVE:To establish the most appropriate prognostic index for use in patients with systemic AIDS-related non-Hodgkin lymphoma. DESIGN:A prospective study involving univ...

journal_title：Annals of internal medicine

authors： Bower M,Gazzard B,Mandalia S,Newsom-Davis T,Thirlwell C,Dhillon T,Young AM,Powles T,Gaya A,Nelson M,Stebbing J

更新日期：2005-08-16 00:00:00

abstract：OBJECTIVE:To describe 13 infections caused by Mycobacterium haemophilum. DESIGN:Identification of patients by microbiologic record review, followed by medical record review and a case-control study. SETTING:Seven metropolitan hospitals in New York. PATIENTS:All patients with M. haemophilum infections diagnosed betwe...

journal_title：Annals of internal medicine

authors： Straus WL,Ostroff SM,Jernigan DB,Kiehn TE,Sordillo EM,Armstrong D,Boone N,Schneider N,Kilburn JO,Silcox VA,LaBombardi V,Good RC

更新日期：1994-01-15 00:00:00

abstract：BACKGROUND:Recent evidence shows that arthroscopic partial meniscectomy (APM) offers no benefit over conservative treatment of patients with a degenerative meniscus tear. However, patients who report mechanical symptoms (sensations of knee catching or locking) may benefit from APM. OBJECTIVE:To assess whether APM impr...

journal_title：Annals of internal medicine

authors： Sihvonen R,Englund M,Turkiewicz A,Järvinen TL,Finnish Degenerative Meniscal Lesion Study Group.

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:In AIDS, nodular skin disease can result from various causes. OBJECTIVE:To report a new manifestation of microsporidial infection presenting as nodular skin disease with underlying osteomyelitis. DESIGN:Case report. SETTING:Tertiary-care military medical center in Washington, D.C. PATIENT:A 36-year-old w...

journal_title：Annals of internal medicine

authors： Kester KE,Turiansky GW,McEvoy PL

更新日期：1998-06-01 00:00:00