当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan.

Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan.

Abstract：

:This case-control study investigated the associations of a history of hypertension, hypercholesterolemia, and diabetes mellitus with the risk of Parkinson's disease (PD) in Japan. Included were 249 cases within 6 years of onset of PD. Controls were 368 inpatients and outpatients without a neurodegenerative disease. Data on the vascular risk factors and confounders were obtained from a self-administered questionnaire. The vascular risk factors were defined based on drug treatment. Adjustment was made for sex, age, region of residence, pack-years of smoking, years of education, leisure-time exercise, body mass index, dietary intake of energy, cholesterol, vitamin E, alcohol, and coffee and the dietary glycemic index. The proportions of hypertension, hypercholesterolemia, and diabetes mellitus prior to the onset of PD were 23.7%, 9.6%, and 4.0%, respectively, in cases. Hypertension, hypercholesterolemia, and diabetes mellitus were significantly associated with a decreased risk of PD: the adjusted ORs were 0.43 (95% CI: 0.29-0.64), 0.58 (95% CI: 0.33-0.97), and 0.38 (95% CI: 0.17-0.79), respectively. No significant differences were observed in the association of vascular risk factors with the risk of PD between men and women. We found evidence of significant inverse associations of hypertension, hypercholesterolemia, and diabetes mellitus with the risk of PD in Japan. Further well-designed investigations of the association of vascular risk factors with the risk of PD are needed, particularly large-scale prospective studies in Asia.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Miyake Y,Tanaka K,Fukushima W,Sasaki S,Kiyohara C,Tsuboi Y,Yamada T,Oeda T,Miki T,Kawamura N,Sakae N,Fukuyama H,Hirota Y,Nagai M,Fukuoka Kinki Parkinson's Disease Study Group.

doi

10.1016/j.jns.2010.03.002

subject

Has Abstract

pub_date

2010-06-15 00:00:00

pages

82-6

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(10)00105-X

journal_volume

293

pub_type

杂志文章,多中心研究

相关文献

JOURNAL OF THE NEUROLOGICAL SCIENCES文献大全
  • Relationship between corpus callosum atrophy and cerebral metabolic asymmetries in multiple sclerosis.

    abstract：:Corpus callosum (CC) atrophy by magnetic resonance imaging (MRI) is a common finding in multiple sclerosis (MS). In order to examine the relationship between CC atrophy and cortical brain metabolism, we compared the cerebral metabolic rates for glucose (CMRglc), measured by positron emission tomography (PET), of 8 MS ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(92)90131-4

    authors： Pozzilli C,Fieschi C,Perani D,Paulesu E,Comi G,Bastianello S,Bernardi S,Bettinardi V,Bozzao L,Canal N

    更新日期：1992-10-01 00:00:00

  • Risk factors for stroke among patients with hypertension: a case-control study.

    abstract：BACKGROUND:In some African countries, more than half of the adult population are estimated to be hypertensive leading to an escalated burden of stroke in the continent. We conducted the first study to unravel the major risk factors for stroke among hypertensive patients (Nigerian-Africans) using a case-control design w...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2012.11.016

    authors： Owolabi MO,Agunloye AM

    更新日期：2013-02-15 00:00:00

  • Disturbance of the glutamatergic system by glutaric acid in striatum and cerebral cortex of glutaryl-CoA dehydrogenase-deficient knockout mice: possible implications for the neuropathology of glutaric acidemia type I.

    abstract：:The role of excitotoxicity on the neuropathology of glutaric acidemia type I (GA I) is still under debate. Therefore, in the present work, we evaluated glutamate uptake by brain slices and glutamate binding to synaptic membranes, as well as glutamine synthetase activity in cerebral cortex and striatum from glutaryl-Co...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.09.003

    authors： Busanello EN,Fernandes CG,Martell RV,Lobato VG,Goodman S,Woontner M,de Souza DO,Wajner M

    更新日期：2014-11-15 00:00:00

  • Metronidazole-induced encephalopathy.

    abstract：:We report the clinical, neuropsychological, and neuroimaging findings of two patients of diffuse encephalopathy associated with the use of metronidazole. Both patients showed characteristic abnormalities on magnetic resonance imaging (MRI) with diffusion weighted imaging (DWI) and recovered incompletely after the disc...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2004.06.012

    authors： Kim DW,Park JM,Yoon BW,Baek MJ,Kim JE,Kim S

    更新日期：2004-09-15 00:00:00

  • Oxfordshire Community Stroke Project classification but not NIHSS predicts symptomatic intracerebral hemorrhage following thrombolysis.

    abstract：BACKGROUND:The Oxfordshire Community Stroke Project (OCSP) classification is a simple tool to categorize clinical stroke syndromes. We compared the outcomes of stroke patients after intravenous thrombolysis stratified by the baseline National Institutes of Health Stroke Scale (NIHSS) score or by the OCSP classification...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2012.10.003

    authors： Sung SF,Wu CS,Hsu YC,Tseng MC,Chen YW

    更新日期：2013-01-15 00:00:00

  • Light chain myeloma with oro-pharyngeal amyloidosis presenting as bulbar paralysis.

    abstract：:A 53-year old woman developed slowly progressive dysarthria, mild enlargement of the tongue and dysphagia since 1 year ago. All neurological differential diagnoses that could have explained the bulbar symptoms were excluded. The swallowing sequence was pathologic and immunoglobulins were markedly reduced. A bone marro...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(96)05326-9

    authors： Finsterer J,Wogritsch C,Pokieser P,Vesely M,Ulrich W,Grisold W,Mamoli B

    更新日期：1997-04-15 00:00:00

  • Assessment of 'on-treatment platelet reactivity' and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis.

    abstract：INTRODUCTION:The relationship between on-treatment platelet reactivity and cerebral micro-embolic signals (MES) is unknown, and has not been previously simultaneously assessed in asymptomatic and symptomatic carotid stenosis patients. METHODS:Consecutive eligible patients with ≥50% asymptomatic or recently symptomatic...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.03.015

    authors： Kinsella JA,Oliver Tobin W,Tierney S,Feeley TM,Egan B,Coughlan T,Ronan Collins D,O'Neill D,Harbison JA,Doherty CP,Madhavan P,Moore DJ,O'Neill SM,Colgan MP,Saqqur M,Murphy RP,Moran N,Hamilton G,McCabe DJH

    更新日期：2017-05-15 00:00:00

  • Incidence of rotational vertigo in supratentorial stroke: a prospective analysis of 112 consecutive patients.

    abstract：BACKGROUND:Single cases with hemispheric, cortical or subcortical, ischemic lesions presenting with rotational vertigo (RV), that challenge the notion of infratentorial or peripheral generation of RV have been published, but the incidence of this symptom in a larger series is unknown. The aim of this study was to inves...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2009.11.015

    authors： Anagnostou E,Spengos K,Vassilopoulou S,Paraskevas GP,Zis V,Vassilopoulos D

    更新日期：2010-03-15 00:00:00

  • Pilot trial of a tele-rehab intervention to improve outcomes after stroke in Ghana: A feasibility and user satisfaction study.

    abstract：BACKGROUND:Tele-rehabilitation after stroke holds promise for under-resourced settings, especially sub-Saharan Africa (SSA), with its immense stroke burden and severely limited physical therapy services. OBJECTIVE:To preliminarily assess the feasibility and outcomes of mobile technology-assisted physical therapy exerc...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2018.01.039

    authors： Sarfo FS,Adusei N,Ampofo M,Kpeme FK,Ovbiagele B

    更新日期：2018-04-15 00:00:00

  • Immunoglobulin gene rearrangement analysis in cerebrospinal fluid of patients with lymphoproliferative processes.

    abstract：OBJECTIVE:To determine the sensitivity and specificity of clonal immunoglobulin heavy chain gene rearrangement (IGHR) analysis in the distinction of benign and malignant lymphoproliferative diseases. METHODS:A retrospective analysis was conducted of patients in whom a malignant lymphoproliferative process was suspecte...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2006.05.044

    authors： Baehring JM,Hochberg FH,Betensky RA,Longtine J,Sklar J

    更新日期：2006-09-25 00:00:00

  • Seasonal variations of 25-OH vitamin D serum levels are associated with clinical disease activity in multiple sclerosis patients.

    abstract：:Low 25-hydroxy vitamin D (25-[OH]-D) serum concentrations have been associated with higher disease activity in multiple sclerosis (MS) patients. In a large cross-sectional study we assessed the vitamin D status in MS patients in relation to seasonality and relapse rate. 415 MS-patients (355 relapsing-remitting MS and ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.01.059

    authors： Hartl C,Obermeier V,Gerdes LA,Brügel M,von Kries R,Kümpfel T

    更新日期：2017-04-15 00:00:00

  • Fingerprint inclusions. Ultrastructural demonstration of muscle fiber type specificity.

    abstract：:Fingerprint inclusions were identified in the skeletal muscle of a child with severe hypotonia. The mean Z-line and M-line widths from each of 19 muscle fibers containing the fingerprint inclusions were calculated. The mean Z-line widths were 85-99 nm, and the mean M-line widths were 75-101 nm. According to out presen...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(77)90216-7

    authors： Payne CM,Curless RG

    更新日期：1977-04-01 00:00:00

  • A census of movement disorders at a Thai university hospital.

    abstract：:There is little information available on the number of patients with movement disorders seen by physicians in Thailand. The authors reviewed the medical records of all movement disorders patients seen at the Chulalongkorn Comprehensive Movement Disorders Center (CUMDS) in Bangkok, Thailand over a 4.5-year period to de...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.11.010

    authors： Bhidayasiri R,Saksornchai K,Kaewwilai L,Phanthumchinda K

    更新日期：2011-02-15 00:00:00

  • Repeated intravenous thrombolysis after recurrent stroke. A case series and review of the literature.

    abstract：BACKGROUND:The likelihood of severe disability and death increases with each recurrent stroke. Repeated intravenous (IV) thrombolysis remains one of the therapeutic options when secondary prevention fails; however, its effects after recurrent stroke are largely unknown. The aim of the present review was to assess the r...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2014.07.039

    authors： Cappellari M,Moretto G,Bovi P

    更新日期：2014-10-15 00:00:00

  • Preservation of the C-terminus of dystrophin molecule in the skeletal muscle from Becker muscular dystrophy.

    abstract：:Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disorder of muscle in children. The DMD gene product, "dystrophin", is absent from DMD, while the allelic disease, Becker muscular dystrophy (BMD), exhibits dystrophin of abnormal size and/or quantity. But we are still uncertain about the scenario that in...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(91)90039-a

    authors： Arahata K,Beggs AH,Honda H,Ito S,Ishiura S,Tsukahara T,Ishiguro T,Eguchi C,Orimo S,Arikawa E

    更新日期：1991-02-01 00:00:00

  • [Hereditary spongiform dystrophy in young children (Canavan: van Bogaert-Bertrand)].

    abstract：:Hereditary spongiform dystrophy in young children is characterised by macrocephaly with spasticity, convulsions and ultimately a decerebrate state and diffuse electroencephalographic changes. Histological examination of the brain remains essential for its diagnosis. A review of the ultrastructural studies reported by ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(76)90101-5

    authors： Mirimanoff P

    更新日期：1976-06-01 00:00:00

  • Elevated fasting blood glucose is predictive of the severity and poor outcome in nondiabetic patients with cerebral venous thrombosis.

    abstract：BACKGROUND AND PURPOSE:Although elevated fasting blood glucose (FBG) at admission is associated with poor outcome in patients with ischemic and hemorrhagic stroke, it has not been investigated in patients with cerebral venous thrombosis (CVT). We aimed to determine the correlation between elevated FBG and severity and ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2020.117017

    authors： Wu Y,Zhou L,Yao M,Zhu Y,Ni J,Cui L,Peng B

    更新日期：2020-10-15 00:00:00

  • Multiple cerebral infarcts and intravascular central nervous system lymphoma: a rare but potentially treatable association.

    abstract：:Intravascular large B-cell lymphoma (IVLBCL) is a rare lymphoproliferative disorder characterized by massive intravascular growth of lymphoma cells with a predilection for the central nervous system (CNS). Diagnosis is generally delayed by variable clinical presentation and nonspecific laboratory findings. Brain biops...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2012.10.012

    authors： Cruto C,Taipa R,Monteiro C,Moreira I,Melo-Pires M,Correia M

    更新日期：2013-02-15 00:00:00

  • Gamma-glutamyl transpeptidase. Elevated activity in myotonic dystrophy.

    abstract：:gamma-Glutamyl transpeptidase, a membrane-bound enzyme playing an important role in the active amino acid transport across cellular membranes, is shown to be elevated in the serum of patients with myotonic muscular dystrophy. No increase of AP, LAP, GOT and GPT activities in the sera of some of the patients studied is...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(76)90105-2

    authors： Alevizos B,Spengos M,Vassilopoulos D,Stefanis C

    更新日期：1976-06-01 00:00:00

  • Utility of auditory P300 in detection of presenile dementia.

    abstract：:The significance of P300 in investigation of the cognitive changes characteristic of aging and dementia is well established. But some controversies about sensitivity and specificity of P300 latency prolongation in detection of dementia still exist, and its predictive value and specificity in "real" clinical situations...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/0022-510x(95)00093-h

    authors： Filipović SR,Kostić VS

    更新日期：1995-08-01 00:00:00

  • Increased intracranial volume in Parkinson's disease.

    abstract：BACKGROUND:Parkinson's disease (PD) and multiple system atrophy (MSA) are neurodegenerative diseases that can be difficult to diagnose and distinguish from each other. STUDY AIMS AND METHODS: Patients with PD and MSA and controls were studied with magnetic resonance imaging (MRI) using tissue segmentation and outlining...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2005.07.013

    authors： Krabbe K,Karlsborg M,Hansen A,Werdelin L,Mehlsen J,Larsson HB,Paulson OB

    更新日期：2005-12-15 00:00:00

  • Covert persistence of mdx mouse myopathy is revealed by acute and chronic effects of irradiation.

    abstract：:To compare muscle fiber loss in young and old mdx mice, we have blocked regeneration in one leg with a high dose (18 Gy) of X-rays administered at two ages; 16 days, just prior to the onset of the myopathy, and 15 weeks, when the myopathy is considered to be quiescent. Mice were examined 4 days after irradiation to lo...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(99)00061-1

    authors： Pagel CN,Partridge TA

    更新日期：1999-04-01 00:00:00

  • Gait analysis in a component timed-up-and-go test using a smartphone application.

    abstract：BACKGROUND:The timed-up-and-go test (TUG) is a popular test for mobility, but it only measures the total time to complete tasks. Recent advances in smartphone technology enables measuring respective times of 6 components in the test (Stand, Go, Turn1, Come, Turns and Sit). We examined availability of these data for ass...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2019.01.023

    authors： Ishikawa M,Yamada S,Yamamoto K,Aoyagi Y

    更新日期：2019-03-15 00:00:00

  • Factors associated with favorable outcome in botulinum toxin A treatment for chronic migraine: A clinic-based prospective study.

    abstract：BACKGROUND:Botulinum toxin A (BTA) responders have elevated levels of calcitonin gene-related and vasoactive intestinal peptides, which are potent vasodilators. We aimed to investigate neurovascular features as a predictor of BTA treatment response in patients with chronic migraine. METHODS:We prospectively recruited ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.01.054

    authors： Lee MJ,Lee C,Choi H,Chung CS

    更新日期：2016-04-15 00:00:00

  • Parcellation-based tractographic modeling of the ventral attention network.

    abstract：INTRODUCTION:The ventral attention network (VAN) is an important mediator of stimulus-driven attention. Multiple cortical areas, such as the middle and inferior frontal gyri, anterior insula, inferior parietal lobule, and temporo-parietal junction have been linked in this processing. However, knowledge of network conne...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2019.116548

    authors： Allan PG,Briggs RG,Conner AK,O'Neal CM,Bonney PA,Maxwell BD,Baker CM,Burks JD,Sali G,Glenn CA,Sughrue ME

    更新日期：2020-01-15 00:00:00

  • A novel monoclonal antibody which reacts with a high molecular weight neuronal cytoplasmic protein and myelin basic protein (MBP) in a patient with macroglobulinemia.

    abstract：:We report on the case of a 70-year-old man with primary macroglobulinemia who showed cranial polyneuropathy and extensive radiculoneuropathy. His serum contained an IgM lambda monoclonal antibody which reacted with both a high molecular weight protein in grey matter and purified myelin basic protein (MBP) on immunoblo...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(96)05305-1

    authors： Kira J,Inuzuka T,Hozumi I,Wada H,Tanaka K,Gondo H,Sato S,Tsuji S,Kobayashi T

    更新日期：1997-05-01 00:00:00

  • Meiotic instability of the CAG repeats in the SCA6/CACNA1A gene in two Japanese SCA6 families.

    abstract：:Intergenerational stability of the CAG repeat number has been considered to be a specific molecular feature of SCA6 compared with other CAG repeat diseases. Nevertheless, we showed meiotic instability of the CAG repeats in the SCA6/CACNL1A gene in two Japanese SCA6 families, including de novo expansion. In one family,...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(01)00466-x

    authors： Shimazaki H,Takiyama Y,Sakoe K,Amaike M,Nagaki H,Namekawa M,Sasaki H,Nakano I,Nishizawa M

    更新日期：2001-04-01 00:00:00

  • The acute effects of alcohol on plasma creatine kinase (CK) activity in the rat.

    abstract：:The acute effect of a single intraperitoneal dose of alcohol (2 g kg-1 body weight) was studied in normally fed rats anaesthetised with sodium pentabarbitone . Rapidly achieved high blood alcohol levels were accompanied by an equally rapid but transient 4-fold increase in the total creatine kinase (CK) activity in the...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(84)90153-9

    authors： Spargo E

    更新日期：1984-03-01 00:00:00

  • Patterns of levels of biological metals in CSF differ among neurodegenerative diseases.

    abstract：:We measured the levels of some biological metals: copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), and zinc (Zn) in the cerebrospinal fluid (CSF) in patients with neurodegenerative diseases (52 patients with amyotrophic lateral sclerosis (ALS)), 21 patients with Alzheimer's disease (AD), and 20 patients with Pa...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.01.003

    authors： Hozumi I,Hasegawa T,Honda A,Ozawa K,Hayashi Y,Hashimoto K,Yamada M,Koumura A,Sakurai T,Kimura A,Tanaka Y,Satoh M,Inuzuka T

    更新日期：2011-04-15 00:00:00

  • The significance of cerebral atrophy for the symptomatology of Parkinson's disease.

    abstract：:Hitherto published results on the impact of brain atrophy on the neurological and psychopathological sympion of this problem without risk of complications. We investigated 173 parkinsonian patients (89 men, 84 women) aged 37--83 years. Besides CT in all patients a standardized neurological and psychopathological inves...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(79)90050-9

    authors： Schneider E,Fischer PA,Jacobi P,Becker H,Hacker H

    更新日期：1979-07-01 00:00:00