Relationship between corpus callosum atrophy and cerebral metabolic asymmetries in multiple sclerosis.

abstract：:We investigated structural changes of the corpus callosum in patients with Alzheimer's disease (AD) using sagittal diffusion-weighted (DW) and magnetization transfer (MT) imaging. Patients with AD (n=23) had a significantly decreased area only in the posterior portion of the corpus callosum. Apparent diffusion coeffic...

journal_title：Journal of the neurological sciences

authors： Hanyu H,Asano T,Sakurai H,Imon Y,Iwamoto T,Takasaki M,Shindo H,Abe K

更新日期：1999-08-01 00:00:00

abstract：:We performed a population based survival analysis of all incident cases (220) of motor neuron disease (MND) in the province of Turin, Italy, during the period 1966-1980. 175 cases were diagnosed as amyotrophic lateral sclerosis (ALS), 43 as progressive muscular atrophy (PMA) and 2 as progressive bulbar palsy (PBP). Th...

journal_title：Journal of the neurological sciences

authors： Mortara P,Chiò A,Rosso MG,Leone M,Schiffer D

更新日期：1984-11-01 00:00:00

abstract：:Myositis was proven histopathologically in 4 patients (age range 36-66 years) who suffered from early or late stages of Borrelia burgdorferi infection. Muscle weakness was present in 3 patients, 1 complaining of additional myalgias. One man came to medical attention because of skin discoloration and swelling of one le...

journal_title：Journal of the neurological sciences

authors： Reimers CD,Pongratz DE,Neubert U,Pilz A,Hübner G,Naegele M,Wilske B,Duray PH,de Koning J

更新日期：1989-06-01 00:00:00

abstract：:We have evaluated cortical excitability in nine patients affected by Wilson's disease (WD) using transcranial magnetic (TMS) and electric (TES) cortical stimulation and central silent period (CSP) data. A clinical score was derived from the sum of scores assigned to extrapyramidal, pyramidal and cerebellar signs. All ...

journal_title：Journal of the neurological sciences

authors： Perretti A,Pellecchia MT,Lanzillo B,Campanella G,Santoro L

更新日期：2001-11-15 00:00:00

abstract：:In five patients with cerebral manifestation of Wilson's disease, copper was measured in CSF, serum, urine and liver, and ceruloplasmin was determined in CSF and serum. CSF copper was found to be elevated in all cases, especially in the four examined before therapy. Two patients were followed up for a period of 3 year...

journal_title：Journal of the neurological sciences

authors： Weisner B,Hartard C,Dieu C

更新日期：1987-06-01 00:00:00

abstract：:Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by segmental vasoconstriction and dilatation of intracranial arteries, usually revealed by headaches, which spontaneously resolve in few weeks. We report a patient with RCVS, revealed by thunderclap headaches, involving both internal and external ca...

journal_title：Journal of the neurological sciences

authors： Melki E,Denier C,Théaudin-Saliou M,Sachet M,Ducreux D,Saliou G

更新日期：2012-02-15 00:00:00

abstract：UNLABELLED:The King-Devick (KD) oculomotor test has recently been advocated for sideline diagnosis of concussion. Although visual processing and performance are often impaired in concussion patients, the utility of KD as a concussion diagnostic tool is not validated. PURPOSE:To examine the diagnostic value of KD, by c...

journal_title：Journal of the neurological sciences

authors： Tjarks BJ,Dorman JC,Valentine VD,Munce TA,Thompson PA,Kindt SL,Bergeron MF

更新日期：2013-11-15 00:00:00

abstract：:The present study used the nerve pathology, studied by quantitative light microscopy, as the sole basis for classification of peroneal muscular atrophy (PMA). The findings in biopsies of superficial peroneal nerves of 20 patients were compared with normal values obtained from 8 controls. Three homogeneous groups compr...

journal_title：Journal of the neurological sciences

authors： Gherardi R,Bouché P,Escourolle R,Hauw JJ

更新日期：1983-10-01 00:00:00

abstract：:We investigated regional cerebral blood flow (rCBF) using the [99mTc]-d,l-HMPAO technique with brain dedicated high resolution single photon emission computer tomography (SPECT) in 14 consecutive patients with amyotrophic lateral sclerosis (ALS), median age 62 years (45-77). Global CBF, expressed in % relative to the ...

journal_title：Journal of the neurological sciences

authors： Waldemar G,Vorstrup S,Jensen TS,Johnsen A,Boysen G

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Cladribine causes sustained reduction in peripheral T and B cell populations while sparing other immune cells. We determined two populations of dendritic cells (DCs): namely CD1c(+)/CD19(-) (myeloid DCs) and CD303(+)/CD123(+) (plasmacytoid DCs), CD19(+) B lymphocytes, CD3(+) T lymphocytes and CD4(+) or CD8(+...

journal_title：Journal of the neurological sciences

authors： Mitosek-Szewczyk K,Tabarkiewicz J,Wilczynska B,Lobejko K,Berbecki J,Nastaj M,Dworzanska E,Kolodziejczyk B,Stelmasiak Z,Rolinski J

更新日期：2013-09-15 00:00:00

abstract：OBJECTIVE:To clarify the prevalence and clinical characteristics of myasthenia gravis (MG) in Japan. METHODS:We performed a nationwide epidemiological survey of MG in Japan. The clinical features were compared among five groups of patients, divided according to onset age. A generalized additive model (GAM) was used to...

journal_title：Journal of the neurological sciences

authors： Murai H,Yamashita N,Watanabe M,Nomura Y,Motomura M,Yoshikawa H,Nakamura Y,Kawaguchi N,Onodera H,Araga S,Isobe N,Nagai M,Kira J

更新日期：2011-06-15 00:00:00

abstract：:The purpose of the investigation was to elucidate the repeatedly discussed relationship between chronic lead intoxication and ALS. The following mean lead concentrations were determined in 9 patients with ALS: 8.65 +/- 3,91 micrograms/100 ml in the blood, 0.97 +/- 0.78 microgram/100 ml in the plasma, 19.15 +/- 5.0 mic...

journal_title：Journal of the neurological sciences

authors： Stober T,Stelte W,Kunze K

更新日期：1983-09-01 00:00:00

abstract：:Juvenile muscular atrophy of the distal upper extremity (JMADUE) is associated with airway allergy and hyperIgEaemia, suggesting the involvement of immunological processes. In this study we aimed to clarify the changes in various cytokines/chemokines in cerebrospinal fluid (CSF) from JMADUE patients. We simultaneously...

journal_title：Journal of the neurological sciences

authors： Tanaka M,Ishizu T,Ochi H,Kawano Y,Ohyagi Y,Kira J

更新日期：2008-12-15 00:00:00

abstract：:MS is a disease that patients can suffer from over several decades. The effects of ageing are therefore likely to have a bearing on the natural history of the disease and the manner in which it is treated. In this review we consider how age affects remyelination, a spontaneously occurring regenerative process that fol...

journal_title：Journal of the neurological sciences

authors： Rist JM,Franklin RJ

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:As available disease-modifying therapies (DMTs) increase, evaluating benefit/risk presents greater difficulties, requiring people with MS (PwMS) to play crucial roles in choosing treatment. Although individual attitude toward risk may predict this evaluation, its relation to personality is little studied in ...

journal_title：Journal of the neurological sciences

authors： Minacapelli E,Giordano A,Falautano M,Sangalli F,Pietrolongo E,Lorefice L,Cocco E,Lugaresi A,Comi G,Filippi M,Martinelli V

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:In Alzheimer's disease, higher educational attainment is associated with fewer cognitive deficits despite similar pathological lesions. In animal models of Parkinson's disease (PD), enhanced levels of cognitive and physical stimulation can reduce motor deficits due to dopaminergic neuronal loss. Therefore, i...

journal_title：Journal of the neurological sciences

authors： Sunwoo MK,Hong JY,Lee JJ,Lee PH,Sohn YH

更新日期：2016-03-15 00:00:00

abstract：OBJECTIVE:To determine the influence of different factors on test-retest reliability of frequently used transcranial magnetic stimulation (TMS) parameters while controlling for potential confounders in healthy subjects. METHODS:TMS was applied in 93 healthy volunteers (61% male) twice (mean retest interval of 34.0 ± 2...

journal_title：Journal of the neurological sciences

authors： Hermsen AM,Haag A,Duddek C,Balkenhol K,Bugiel H,Bauer S,Mylius V,Menzler K,Rosenow F

更新日期：2016-03-15 00:00:00

abstract：:Neuropathy has been frequently reported in patients with IgG monoclonal gammopathy of undetermined significance (MGUS) but it is still unclear whether this association has clinical or pathogenetic relevance. In order to clarify the possible role of IgG MGUS in the neuropathy we correlated the clinical and electrophysi...

journal_title：Journal of the neurological sciences

authors： Di Troia A,Carpo M,Meucci N,Pellegrino C,Allaria S,Gemignani F,Marbini A,Mantegazza R,Sciolla R,Manfredini E,Scarlato G,Nobile-Orazio E

更新日期：1999-03-15 00:00:00

abstract：:Laryngeal stridor is recognized as a characteristic clinical manifestation in patients with multiple system atrophy (MSA). However, the pathogenic mechanisms underlying this symptom are controversial. Neurogenic atrophy of the posterior cricoarytenoid muscle has been identified in cases of MSA, suggesting that larynge...

journal_title：Journal of the neurological sciences

authors： Ozawa T,Sekiya K,Aizawa N,Terajima K,Nishizawa M

更新日期：2016-02-15 00:00:00

abstract：:Menkes' disease is an inherited disturbance of copper metabolism. Addition of copper to the medium of cultured fibroblasts and lymphoblasts from patients with Menkes' disease results in an increased induction of metallothionein. We investigated the metallothionein induction in response to copper and zinc in muscle cel...

journal_title：Journal of the neurological sciences

authors： Herzberg NH,Wolterman RA,van den Berg GJ,Barth PG,Bolhuis PA

更新日期：1990-12-01 00:00:00

abstract：:The case of an 18-year-old woman is reported who had developed progressive inability to use her left limbs since the age of 13 years. Ataxic hemiparesis was noted on the left side. A CT scan of the brain revealed a non-enhancing hypodense lesion in the cerebellopontine angle with a supratentorial extension consistent ...

journal_title：Journal of the neurological sciences

authors： Gupta PK,Anjaneyulu A,Borgohain R,Dinakar I

更新日期：1994-09-01 00:00:00

abstract：:Low 25-hydroxy vitamin D (25-[OH]-D) serum concentrations have been associated with higher disease activity in multiple sclerosis (MS) patients. In a large cross-sectional study we assessed the vitamin D status in MS patients in relation to seasonality and relapse rate. 415 MS-patients (355 relapsing-remitting MS and ...

journal_title：Journal of the neurological sciences

authors： Hartl C,Obermeier V,Gerdes LA,Brügel M,von Kries R,Kümpfel T

更新日期：2017-04-15 00:00:00

abstract：:We measured the levels of some biological metals: copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), and zinc (Zn) in the cerebrospinal fluid (CSF) in patients with neurodegenerative diseases (52 patients with amyotrophic lateral sclerosis (ALS)), 21 patients with Alzheimer's disease (AD), and 20 patients with Pa...

journal_title：Journal of the neurological sciences

authors： Hozumi I,Hasegawa T,Honda A,Ozawa K,Hayashi Y,Hashimoto K,Yamada M,Koumura A,Sakurai T,Kimura A,Tanaka Y,Satoh M,Inuzuka T

更新日期：2011-04-15 00:00:00

abstract：:Psychiatric and intellectual comorbidities are common in patients with epilepsy. However, data on the use of antiepileptic drugs in these patients are still lacking. This study assessed the real-world effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients with intellectual disability and ps...

journal_title：Journal of the neurological sciences

authors： Doherty CP,Rheims S,Assenza G,Boero G,Chaves J,McMurray R,Villanueva V

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND AND PURPOSE:Delirium frequently complicates acute stroke and worsens outcomes. Because delirium is potentially preventable, predicting its occurrence is essential. Although several prediction scores have been proposed, nurses need to quickly predict delirium in stroke care units (SCUs). We aimed to develop a...

journal_title：Journal of the neurological sciences

authors： Nakamizo T,Kanda T,Kudo Y,Sugawara E,Hashimoto E,Okazaki A,Usuda M,Nagai T,Hara H,Johkura K

更新日期：2020-08-15 00:00:00

abstract：BACKGROUND:Ischemic stroke is the end phenotype of a complex interaction between various genetic and environmental factors. OBJECTIVE:We aimed to explore association of two lipid-relevant genetic variants and conventional risk factors with risk of having ischemic stroke in Northern Han Chinese. METHODS:Genotyping was...

journal_title：Journal of the neurological sciences

authors： Wang B,Zhao H,Zhou L,Dai X,Wang D,Cao J,Niu W

更新日期：2009-01-15 00:00:00

abstract：:Post stroke dementia (PSD) develops in up to 40% of patients and often co-exists with Alzheimer's disease in the elderly. Unsurprisingly, the combination of stroke and dementia is associated with considerable morbidity and mortality, and is devastating to patients and carers. Limited trial evidence suggests that lower...

journal_title：Journal of the neurological sciences

authors： Ankolekar S,Geeganage C,Anderton P,Hogg C,Bath PM

更新日期：2010-12-15 00:00:00

abstract：:Somatosensory evoked potentials (SEPs) following median nerve stimulation were abnormal in 7 patients with sensory impairment due to vitamin B12 deficiency. Extensor plantar reflexes indicated a central sensory pathway lesion in 4 cases and absent tendon jerks suggested peripheral neuropathy in 4, but median nerve SEP...

journal_title：Journal of the neurological sciences

authors： Jones SJ,Yu YL,Rudge P,Kriss A,Gilois C,Hirani N,Nijhawan R,Norman P,Will R

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:There is insufficient data on the efficacy of intravenous immunoglobulins (IVIg) as maintenance treatment in myasthenia gravis (MG). We therefore examined response to maintenance IVIg therapy in a cohort of MG patients. METHODS:We reviewed all MG patient files treated with IVIg in our neuro-immunology clini...

journal_title：Journal of the neurological sciences

authors： Hellmann MA,Mosberg-Galili R,Lotan I,Steiner I

更新日期：2014-03-15 00:00:00

abstract：:Multiple studies on cerebral ischemia have been performed in animal models to propose different strategies of neuroprotection that mitigate either the early or late consequences of the disease. These therapies have been successful in reducing the volume of infarction, the proinflammatory cascade, and the amount of fre...

journal_title：Journal of the neurological sciences

authors： Gutiérrez-Vargas JA,Cardona-Gómez GP

更新日期：2020-01-15 00:00:00