Pilot trial of a tele-rehab intervention to improve outcomes after stroke in Ghana: A feasibility and user satisfaction study.

Abstract:

BACKGROUND:Tele-rehabilitation after stroke holds promise for under-resourced settings, especially sub-Saharan Africa (SSA), with its immense stroke burden and severely limited physical therapy services. OBJECTIVE:To preliminarily assess the feasibility and outcomes of mobile technology-assisted physical therapy exercises for stroke survivors in Ghana. METHODS:We conducted a prospective, single arm, pre-post study involving 20 stroke survivors recruited from a tertiary medical center, who received a Smartphone with the 9zest Stroke App® to deliver individualized, goal-targeted 5-days-a-week exercise program that was remotely supervised by a tele-therapist for 12 weeks. Outcome measures included changes in stroke levity scale scores (SLS), Modified Rankin score (MRS), Montreal Cognitive Assessment (MOCA), and feasibility indicators. RESULTS:Among study participants, mean ± SD age was 54.6 ± 10.2 years, 11 (55%) were men, average time from stroke onset was 6 months. No participants dropped out. Compared with baseline status, mean ± SD scores on SLS improved from 7.5 ± 3.1 to 11.8 ± 2.2 at month 1 (p < 0.0001) and 12.2 ± 2.4 at month 3 (p < 0.0001), MOCA scores improved from 18.2 ± 4.3 to 20.4 ± 4.7 at month 1 (p = 0.14), and 22.2 ± 7.6 at month 3 (p = 0.047). Mean ± SD weekly sessions performed by participants per month was 5.7 ± 5.8 and duration of sessions was 25.5 ± 16.2 min. Erratic internet connectivity negatively affected full compliance with the intervention, although satisfaction ratings by study participants were excellent. CONCLUSION:It is feasible to administer an m-health delivered physical therapy intervention in SSA, with high user satisfaction. Randomized trials to assess the efficacy and cost-effectiveness of this intervention are warranted.

journal_name

J Neurol Sci

authors

Sarfo FS,Adusei N,Ampofo M,Kpeme FK,Ovbiagele B

doi

10.1016/j.jns.2018.01.039

subject

Has Abstract

pub_date

2018-04-15 00:00:00

pages

94-97

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(18)30055-8

journal_volume

387

pub_type

杂志文章
  • Human brain growth in the 19th and 20th century.

    abstract::Data of 2399 brain weights and ages from populations before 1880, 1885 to 1900 and 1966 to 1976 were obtained from German anatomical and pathological institutes, analyzed with non-linear and multiple linear regression analyses and the results compared. The influence of the absolute age (sample period) on brain weights...

    journal_title:Journal of the neurological sciences

    pub_type: 历史文章,杂志文章

    doi:10.1016/0022-510x(79)90202-8

    authors: Kretschmann HJ,Schleicher A,Wingert F,Zilles K,Löblich HJ

    更新日期:1979-02-01 00:00:00

  • Hydroxychloroquine reduces microglial activity and attenuates experimental autoimmune encephalomyelitis.

    abstract:BACKGROUND:Microglial activation is thought to be a key pathophysiological mechanism underlying disease activity in all forms of MS. Hydroxychloroquine (HCQ) is an antimalarial drug with immunomodulatory properties that is widely used in the treatment of rheumatological diseases. In this series of experiments, we explo...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.08.1525

    authors: Koch MW,Zabad R,Giuliani F,Hader W Jr,Lewkonia R,Metz L,Wee Yong V

    更新日期:2015-11-15 00:00:00

  • Effects of cholinergic drugs on learning impairment in ventral globus pallidus-lesioned rats.

    abstract::The excitotoxin kainic acid (10 nmol/microliter) was used to produce bilateral lesions in the nucleus basalis magnocellularis (NBM) of rats which provides extensive cholinergic innervation to the cerebral cortex. The behavioral effects of physostigmine, THA (9-amino-1,2,3,4-tetrahydroacridine hydrochloride) and NIK-24...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(89)90041-5

    authors: Ueki A,Miyoshi K

    更新日期:1989-03-01 00:00:00

  • Normal CSF neuron-specific enolase and S-100 protein levels in patients with recent non-complicated tonic-clonic seizures.

    abstract:PURPOSE:Increased concentrations of the nervous-system-specific proteins neuron-specific enolase (NSE) and S-100 protein (S-100) have been measured with lesions in the CNS. Elevated levels of serum NSE (s-NSE) have been found in status epilepticus, but also after single epileptic seizures. Because larger studies addres...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(00)00478-0

    authors: Palmio J,Peltola J,Vuorinen P,Laine S,Suhonen J,Keränen T

    更新日期:2001-01-15 00:00:00

  • Th2 shift in mononeuritis multiplex and increase of Th2 cells in chronic inflammatory demyelinating polyneuropathy: an intracellular cytokine analysis.

    abstract::To elucidate the T helper 1 (Th1)/T helper 2 (Th2) balance in various inflammatory neuropathies, we measured the ratio of intracellular interferon-gamma (IFN-gamma)-positive to IL-4-positive cells (intracellular IFN-gamma/IL-4 ratio) by flow cytometry in peripheral blood CD4(+) T cells of 14 patients with mononeuritis...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(01)00603-7

    authors: Horiuchi I,Ochi H,Murai H,Osoegawa M,Minohara M,Furuya H,Kira J

    更新日期:2001-12-15 00:00:00

  • Effects of long-term whole-body vibration training on mobility in patients with multiple sclerosis: A meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:This meta-analysis evaluated feasibility and efficacy of long-term whole-body vibration (WBV) training in improving mobility of multiple sclerosis (MS) patients. METHODS:The primary search of this meta-analysis was conducted from four electronic databases (PubMed, Sport, CINAHL and Cochrane) in order to fin...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jns.2015.09.357

    authors: Kantele S,Karinkanta S,Sievänen H

    更新日期:2015-11-15 00:00:00

  • LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor.

    abstract::Leucine-rich repeats and immunoglobulin-like domains (LRIG) 3 gene is mapped to chromosome 12q13.2, a region that is frequently deleted in a subset of glioblastoma multiforme (GBM). It has been reported that perinuclear LRIG3 staining correlated with low WHO grade of glioma and better survival of the patients. However...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.02.015

    authors: Guo D,Yang H,Guo Y,Xiao Q,Mao F,Tan Y,Wan X,Wang B,Lei T

    更新日期:2015-03-15 00:00:00

  • Burden of non-motor symptoms in unclear parkinsonism and tremor: A study with [123I]FP-CIT SPECT.

    abstract:BACKGROUND:Non-motor symptoms (NMSs) are clearly more prevalent in Parkinson's disease (PD) patients compared to healthy individuals. However, NMSs are also common in the elderly and other neurological conditions, and thus, it is not known whether NMSs could be used to differentiate PD from parkinsonism/tremor without ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2019.07.025

    authors: Jaakkola E,Joutsa J,Mäkinen E,Noponen T,Pitkonen M,Levo R,Mertsalmi T,Scheperjans F,Kaasinen V

    更新日期:2019-09-15 00:00:00

  • Assessment of 'on-treatment platelet reactivity' and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis.

    abstract:INTRODUCTION:The relationship between on-treatment platelet reactivity and cerebral micro-embolic signals (MES) is unknown, and has not been previously simultaneously assessed in asymptomatic and symptomatic carotid stenosis patients. METHODS:Consecutive eligible patients with ≥50% asymptomatic or recently symptomatic...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2017.03.015

    authors: Kinsella JA,Oliver Tobin W,Tierney S,Feeley TM,Egan B,Coughlan T,Ronan Collins D,O'Neill D,Harbison JA,Doherty CP,Madhavan P,Moore DJ,O'Neill SM,Colgan MP,Saqqur M,Murphy RP,Moran N,Hamilton G,McCabe DJH

    更新日期:2017-05-15 00:00:00

  • Sleep hygiene and its association with daytime sleepiness, depressive symptoms, and quality of life in patients with mild obstructive sleep apnea.

    abstract:PURPOSE:To investigate the direct and indirect associations of sleep hygiene with daytime sleepiness, depressive symptoms, and quality of life (QoL), in newly diagnosed, untreated patients with mild obstructive sleep apnea (OSA). METHODS:Data were collected from adults with mild OSA. The Sleep Hygiene Index (SHI), Sle...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.10.017

    authors: Lee SA,Paek JH,Han SH

    更新日期:2015-12-15 00:00:00

  • Lower urinary tract dysfunction in patients with functional movement disorders.

    abstract:INTRODUCTION:Functional movement disorders (FMD) are not associated with the kind of structural or biochemical alterations seen in other movement disorders and therefore would be unlikely to be associated with lower urinary tract (LUT) dysfunction. However, LUT symptoms have been observed in patients with FMD. OBJECTI...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.12.048

    authors: Batla A,Pareés I,Edwards MJ,Stamelou M,Bhatia KP,Panicker JN

    更新日期:2016-02-15 00:00:00

  • Morphometric and high resolution scanning electron microscopy analysis of low-level laser therapy and latex protein (Hevea brasiliensis) administration following a crush injury of the sciatic nerve in rats.

    abstract::This study evaluated the effect of low-level laser therapy (LLLT; 15 J/cm(2)) and a latex protein (F1) on a crush injury of the sciatic (ischiadicus) nerve. Seventy-two rats (male, 250 g) were divided into 6 groups: CG, control; EG, exposed nerve; IG, injured nerve without treatment; LG, injured nerve with LLLT; HG, i...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2014.12.043

    authors: Dias FJ,Issa JP,Coutinho-Netto J,Fazan VP,Sousa LG,Iyomasa MM,Papa PC,Watanabe IS

    更新日期:2015-02-15 00:00:00

  • Adverse changes in fibre type composition of the human masseter versus biceps brachii muscle during aging.

    abstract::The fibre composition of functionally different regions, the superficial and the deep portions, of the human masseter and the biceps brachii muscles of six elderly subjects (mean age 74 years) was studied by morphological and enzyme-histochemical methods. When compared to previous data for young adults, the masseter m...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(97)00208-6

    authors: Monemi M,Eriksson PO,Eriksson A,Thornell LE

    更新日期:1998-01-21 00:00:00

  • High resolution positron emission tomography demonstrates basal ganglia dysfunction in early Parkinson's disease.

    abstract::High resolution positron emission tomography (PET) with the newly developed HRRT scanner (Siemens/CTI) permits the reliable quantification of 18-Fluorodeoxyglucose (FDG) uptake as a marker of neuronal activity in small subcortical nuclei which are involved in the pathophysiology of Parkinson's disease (PD). We investi...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2008.08.029

    authors: Eggers C,Hilker R,Burghaus L,Schumacher B,Heiss WD

    更新日期:2009-01-15 00:00:00

  • Chronic progressive spinobulbar spasticity with disturbance of voluntary eyelid closure. Report of a case with special reference to MRI and electrophysiological findings.

    abstract::We describe a 56-year-old man who had a progressive pseudobulbar palsy, spastic tetraparesis, forced laughing and disturbance of voluntary eyelid closure, and was clinically compatible with chronic progressive spinobulbar spasticity. Magnetic resonance images (MRI) revealed atrophy of the bilateral motor cortices and ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(90)90131-6

    authors: Nishimura M,Tojima M,Suga M,Hirose K,Tanabe H

    更新日期:1990-05-01 00:00:00

  • Occurrence of fatigue over 20 years after recovery from Guillain-Barré syndrome.

    abstract:INTRODUCTION:Reports regarding outcome of Guillain-Barré syndrome (GBS) are usually limited to relatively short follow-up. We assessed the occurrence of fatigue and correlated it to clinical measures in patients who had suffered from GBS over 20 years previously. METHODS:We contacted 24 patients with GBS requiring in-...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2012.01.024

    authors: Drory VE,Bronipolsky T,Bluvshtein V,Catz A,Korczyn AD

    更新日期:2012-05-15 00:00:00

  • Unusual features of the Guillain-Barré syndrome after rabies vaccine prepared in suckling mouse brain.

    abstract::Five patients with acute polyneuritis following treatment with rabies vaccine prepared in suckling mouse brains are reported. These patients had severe and protracted disease. The extensive cranial nerve involvement, high mortality rate, and disabling longterm sequelae were in contrast to cases of the Guillain-Barré s...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(87)90099-2

    authors: Cabrera J,Griffin DE,Johnson RT

    更新日期:1987-11-01 00:00:00

  • Motor-dominant polyneuropathy due to IgM monoclonal antibody against disialosyl gangliosides in a patient with mantle cell lymphoma.

    abstract::A rapidly progressive motor-dominant neuropathy associated with IgM monoclonal antibody against gangliosides with disialosyl residues, GD3, GD1b, GT1b, and GQ1b, in a 60-year-old Japanese man with mantle cell lymphoma is reported. Plasma exchange and chemotherapy for mantle cell lymphoma were performed for the neuropa...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2013.11.026

    authors: Mori A,Ueno Y,Kuroki T,Hoshino Y,Shimura H,Sekiguchi Y,Noguchi M,Hamada Y,Kusunoki S,Hattori N,Urabe T

    更新日期:2014-02-15 00:00:00

  • Effects of the rotigotine transdermal patch versus oral levodopa on swallowing in patients with Parkinson's disease.

    abstract:OBJECTIVES:Abnormal swallowing or dysphagia is a potentially fatal symptom in Parkinson's disease (PD) and is characterized by frequent silent aspiration, which is an unrecognized risk for aspiration pneumonia. While the effects of oral levodopa on swallowing functions remain controversial, several small-scale studies ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2019.07.003

    authors: Hirano M,Isono C,Fukuda K,Ueno S,Nakamura Y,Kusunoki S

    更新日期:2019-09-15 00:00:00

  • NMO sera down-regulate AQP4 in human astrocyte and induce cytotoxicity independent of complement.

    abstract::Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are highly specific for neuromyelitis optica (NMO). However, the molecular mechanism of NMO still remains unclear. The purpose of this study was to identify the possible humoral mechanisms responsible for the occurrence of astrocytic damage. Human prima...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2013.05.035

    authors: Haruki H,Sano Y,Shimizu F,Omoto M,Tasaki A,Oishi M,Koga M,Saito K,Takahashi T,Nakada T,Kanda T

    更新日期:2013-08-15 00:00:00

  • Neurocysticercosis presenting as a vertical one-and-a-half syndrome with associated contralesional horizontal gaze paresis.

    abstract::We describe a patient presenting with vertical one-and-a-half syndrome and concomitant contralesional horizontal gaze paresis as the result of a solitary neurocysticercosis (NCC) lesion in the right midbrain extending into the thalamomesencephalic junction. The patient received an albendazole-dexamethasone course whic...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2012.08.022

    authors: Mesraoua B,Deleu D,D'souza A,Imam YZ,Melikyan G

    更新日期:2012-12-15 00:00:00

  • Light chain myeloma with oro-pharyngeal amyloidosis presenting as bulbar paralysis.

    abstract::A 53-year old woman developed slowly progressive dysarthria, mild enlargement of the tongue and dysphagia since 1 year ago. All neurological differential diagnoses that could have explained the bulbar symptoms were excluded. The swallowing sequence was pathologic and immunoglobulins were markedly reduced. A bone marro...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(96)05326-9

    authors: Finsterer J,Wogritsch C,Pokieser P,Vesely M,Ulrich W,Grisold W,Mamoli B

    更新日期:1997-04-15 00:00:00

  • Non-familial degenerative disease and atrophy of brainstem and cerebellum. Clinical and CT data in 47 patients.

    abstract::We studied the clinical features of 47 patients with a non-hereditary degenerative disease and with atrophy of brainstem or cerebellum or both in CT scanning. There was no relation between the CT findings and duration or severity of the disease, nor with the kind of the neurological signs which comprised ataxia, a hyp...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(90)90073-v

    authors: Staal A,Meerwaldt JD,van Dongen KJ,Mulder PG,Busch HF

    更新日期:1990-03-01 00:00:00

  • Visual deprivation elicits subclinical postural inflexibilities in early Parkinson's disease.

    abstract:BACKGROUND:Postural instability is often experienced in the late stages of PD and is a marker of disease progression. Little information is available on the role of visual inputs as an adaptive strategy to compensate for postural instability in PD. The purpose of this study was to determine visual dependency for postur...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.01.022

    authors: Panyakaew P,Anan C,Bhidayasiri R

    更新日期:2015-02-15 00:00:00

  • Two-dimensional immunoelectrophoresis of unconcentrated cerebrospinal fluid.

    abstract::The two-dimensional immunoelectrophoresis on cellulose acetate, already utilized for serum proteins, has been applied to CSF proteins. The technical modifications which allow the use of unconcentrated CSF are described. By utilizing a particularly suitable supporting medium, a good separation of proteins is achieved; ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(78)90203-4

    authors: Baggio G,Bertolotto A,Moretti MG,Palmucci LC

    更新日期:1978-07-01 00:00:00

  • Sensorimotor network in cervical dystonia and the effect of botulinum toxin treatment: a functional MRI study.

    abstract:BACKGROUND:The evidence suggests that the origin of primary dystonia is at least partly associated with widespread dysfunction of the basal ganglia and cortico-striato-thalamo-cortical circuits. The aim of the study was to assess the sensorimotor activation pattern outside the circuits controlling the affected body par...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jns.2011.03.040

    authors: Opavský R,Hluštík P,Otruba P,Kaňovský P

    更新日期:2011-07-15 00:00:00

  • Hippocampal size and dementia in stroke patients: the Sydney stroke study.

    abstract:BACKGROUND:Hippocampal atrophy is an early feature of Alzheimer's disease (AD) but it has also been reported in vascular dementia (VaD). It is uncertain whether hippocampal size can help differentiate the two disorders. METHODS:We assessed 90 stroke/TIA patients 3-6 months after the event, and 75 control subjects, wit...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2007.04.006

    authors: Sachdev PS,Chen X,Joscelyne A,Wen W,Altendorf A,Brodaty H

    更新日期:2007-09-15 00:00:00

  • Multiple sclerosis associated with Leber's Hereditary Optic Neuropathy.

    abstract::The cause of multiple sclerosis is unknown although it is recognised to involve an inflammatory process associated with demyelinating plaques and more widespread neurodegeneration. It appears to have become progressively more common in females which is further discussed in this issue, and genetic factors, as identifie...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.jns.2009.09.009

    authors: Palace J

    更新日期:2009-11-15 00:00:00

  • Temporal profile of thromboxane-prostacyclin imbalance in experimental spinal cord injury.

    abstract::Thromboxane-prostacyclin imbalance may be an important determinant of platelet-vessel wall interactions that are vital in circulatory homeostasis. In experimental spinal cord injury, the vascular damage contributes substantially to the process of progressive secondary injury culminating in post-traumatic myelopathy. I...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(88)90019-6

    authors: Hsu CY,Halushka PV,Spicer KM,Hogan EL,Martin HF

    更新日期:1988-01-01 00:00:00

  • Covert persistence of mdx mouse myopathy is revealed by acute and chronic effects of irradiation.

    abstract::To compare muscle fiber loss in young and old mdx mice, we have blocked regeneration in one leg with a high dose (18 Gy) of X-rays administered at two ages; 16 days, just prior to the onset of the myopathy, and 15 weeks, when the myopathy is considered to be quiescent. Mice were examined 4 days after irradiation to lo...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(99)00061-1

    authors: Pagel CN,Partridge TA

    更新日期:1999-04-01 00:00:00