Metronidazole-induced encephalopathy.

abstract：:Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disorder of muscle in children. The DMD gene product, "dystrophin", is absent from DMD, while the allelic disease, Becker muscular dystrophy (BMD), exhibits dystrophin of abnormal size and/or quantity. But we are still uncertain about the scenario that in...

journal_title：Journal of the neurological sciences

authors： Arahata K,Beggs AH,Honda H,Ito S,Ishiura S,Tsukahara T,Ishiguro T,Eguchi C,Orimo S,Arikawa E

更新日期：1991-02-01 00:00:00

abstract：:Vitamin B1- and B-deficient encephalopathy was produced in adult Wistar rats and the effect of methylcobalamin was studied. These experiments were performed in vitamin B1- or B-deficient rats with or without the administration of guanidine, a magnesium antagonist. These encephalopathic rats showed symmetrical lesions ...

journal_title：Journal of the neurological sciences

authors： Goto I,Nagara H,Tateishi J,Kuroiwa Y

更新日期：1987-01-01 00:00:00

abstract：:To improve the understanding of neuronal cell swelling in cerebral ischemia, cell volume regulation, viability, intracellular electrolytes, and lactate production of Neuro-2A neuroblastoma cells were studied using an in vitro model. The volume regulatory capacity of Neuro-2A cells was assessed after incubation in hypo...

journal_title：Journal of the neurological sciences

authors： Mackert BM,Staub F,Peters J,Baethmann A,Kempski O

更新日期：1996-07-01 00:00:00

abstract：:Cultured post-fused human skeletal muscle monolayers exposed to WSN influenza A virus were analyzed by scanning and transmission electron microscopy. At 12-14h post-inoculation (p.i.), affected mononuclear cells retracted from the cell surface, but remained anchored to the substrate by taut filar processes. Retraction...

journal_title：Journal of the neurological sciences

authors： Miranda AF,Gamboa ET,Armstrong CL,Hsu KC

更新日期：1978-03-01 00:00:00

abstract：:The thyroid hormone thyroxine (T4), administered post-natally to neonatal rats, has been shown to accelerate development of auditory function, as expressed by auditory nerve-brainstem evoked responses. This study investigated whether this earlier development was also reflected in other sensory modalities. Rat pups wer...

journal_title：Journal of the neurological sciences

authors： Freeman S,Sohmer H

更新日期：1995-02-01 00:00:00

abstract：:We measured the diameter of the most distal portion of the axonal initial segment, the neuronal size of anterior horn cells, and the length of the axon hillock plus the initial segment (AH+IS) in the lumbar spinal cord in motor neuron disease. Three patients with amyotrophic lateral sclerosis (ALS) and one with lower ...

journal_title：Journal of the neurological sciences

authors： Sasaki S,Maruyama S

更新日期：1992-07-01 00:00:00

abstract：:The significance of P300 in investigation of the cognitive changes characteristic of aging and dementia is well established. But some controversies about sensitivity and specificity of P300 latency prolongation in detection of dementia still exist, and its predictive value and specificity in "real" clinical situations...

journal_title：Journal of the neurological sciences

authors： Filipović SR,Kostić VS

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Direct oral anticoagulants (DOACs) can reduce the frequency of cardioembolic stroke with non-valvular atrial fibrillation as well as or better compared to vitamin K antagonists (VKAs). However, whether taking DOACs prior to stroke can prevent acute major cerebral artery occlusion (MCAO) has not been fully el...

journal_title：Journal of the neurological sciences

authors： Tomari S,Arima J,Yoshida T,Yamashita H,Sata R,Hamada R,Kanda N,Takashima H

更新日期：2019-07-15 00:00:00

abstract：:Recently an association between statins and the onset and more rapid disease course of amyotrophic lateral sclerosis (ALS) was reported, while other studies rejected such a link. The role of gender in that controversy is unclear. We evaluated the gender-specific effect of statins on the rate of functional decline in p...

journal_title：Journal of the neurological sciences

authors： Nefussy B,Hirsch J,Cudkowicz ME,Drory VE

更新日期：2011-01-15 00:00:00

abstract：:Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are highly specific for neuromyelitis optica (NMO). However, the molecular mechanism of NMO still remains unclear. The purpose of this study was to identify the possible humoral mechanisms responsible for the occurrence of astrocytic damage. Human prima...

journal_title：Journal of the neurological sciences

authors： Haruki H,Sano Y,Shimizu F,Omoto M,Tasaki A,Oishi M,Koga M,Saito K,Takahashi T,Nakada T,Kanda T

更新日期：2013-08-15 00:00:00

abstract：:We performed post-mortem examinations of three patients with progressive neurogenic amyotrophy of long duration. One patient had been clinically diagnosed as having sporadic amyotrophic lateral sclerosis (ALS) and two had been diagnosed with progressive spinal muscular atrophy (PSMA). The disease durations were 10, 17...

journal_title：Journal of the neurological sciences

authors： Iwanaga K,Hayashi S,Oyake M,Horikawa Y,Hayashi T,Wakabayashi M,Kondo H,Tsuji S,Takahashi H

更新日期：1997-03-10 00:00:00

abstract：:In this study, we examined transient ischemia-induced changes in transcription factor E2F1 and c-myb expressions in the gerbil hippocampus after 5 min of transient forebrain ischemia. E2F1 immunoreactivity significantly increased in the CA1 region 6-12 h after ischemia/reperfusion. c-myb immunoreactivity increased mai...

journal_title：Journal of the neurological sciences

authors： Hwang IK,Yoo KY,Cho BM,Hwang HS,Kim SM,Oh SM,Choi SK,Hwang DY,Won MH,Moon SM

更新日期：2006-09-25 00:00:00

abstract：:Several neuroimaging techniques are promising tools as early markers of brain pathology in Alzheimer's disease (AD). On structural MRI, atrophy of the entorhinal cortex is present already in mild cognitive impairment (MCI). In the autosomal dominant forms of AD, the rate of atrophy of medial temporal structures separa...

journal_title：Journal of the neurological sciences

authors： Masdeu JC,Zubieta JL,Arbizu J

更新日期：2005-09-15 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) and cholecystokinin (CCK) have been measured, by radioimmunoassay, in cerebral cortex obtained at autopsy from patients without neurological or psychiatric disease and from patients with Alzheimer's disease, depression and schizophrenia. Sephadex gel filtration indicated that over 9...

journal_title：Journal of the neurological sciences

authors： Perry RH,Dockray GJ,Dimaline R,Perry EK,Blessed G,Tomlinson BE

更新日期：1981-09-01 00:00:00

abstract：INTRODUCTION:The underlying pathophysiology of neurological complications in patients with hemolytic-uremic syndrome (HUS) remains unclear. It was recently attributed to a direct cytotoxic effect of Shiga toxin 2 (Stx2) in the thalamus. Conventional MRI of patients with Stx2-caused HUS revealed - despite severe neurolo...

journal_title：Journal of the neurological sciences

authors： Krämer J,Deppe M,Göbel K,Tabelow K,Wiendl H,Meuth SG

更新日期：2015-09-15 00:00:00

abstract：:Impairment of nervous function and thiamine metabolism were studied in 40 patients suffering from pernicious anaemia, 20 of whom had not been treated and the other 20 were on hydroxocobalamin therapy. Of the untreated patients 13 (65%) showed signs of peripheral nerve dysfunction with reduced conduction velocities, as...

journal_title：Journal of the neurological sciences

authors： Cox-Klazinga M,Endtz LJ

更新日期：1980-03-01 00:00:00

abstract：:To develop diagnostic criteria for chronic inflammatory demyelinating polyneuropathy (CIDP), a retrospective series of patients' records diagnosed by sexpert consensus as CIDP or other chronic polyneuropathies were analyzed. Classification and regression tree analysis was applied to 150 patients to derive a classifica...

journal_title：Journal of the neurological sciences

authors： Koski CL,Baumgarten M,Magder LS,Barohn RJ,Goldstein J,Graves M,Gorson K,Hahn AF,Hughes RA,Katz J,Lewis RA,Parry GJ,van Doorn P,Cornblath DR

更新日期：2009-02-15 00:00:00

abstract：:Nitric oxide (NO) may be involved in myelin and oligodendrocyte injury associated with multiple sclerosis (MS), a demyelinating disease of unknown etiology. The cerebrospinal fluid (CSF) from MS patients may provide an important signal inducing a pathologic process within the central nervous system (CNS). To investiga...

journal_title：Journal of the neurological sciences

authors： Xiao BG,Zhang GX,Ma CG,Link H

更新日期：1996-10-01 00:00:00

abstract：:Five French families with Creutzfeldt-Jakob disease (CJD) were found to have either of 2 different point mutations (at codons 178 and 200) in the amyloid precursor gene (PRNP) on chromosome 20. The ancestry of these and other CJD families outside of France suggests that the codon 178 mutation had a northern European o...

journal_title：Journal of the neurological sciences

authors： Brown P,Goldfarb LG,Cathala F,Vrbovská A,Sulima M,Nieto A,Gibbs CJ Jr,Gajdusek DC

更新日期：1991-10-01 00:00:00

abstract：:An immunocytochemical study of surface and cytoplasmic markers of the monocyte/macrophage lineage was undertaken on peripheral blood (PB) and cerebrospinal fluid (CSF) cells in patients with multiple sclerosis (MS) or other neurological diseases (OND) and in three healthy controls. Size and granularity were assessed b...

journal_title：Journal of the neurological sciences

authors： Salmaggi A,Sandberg-Wollheim M

更新日期：1993-12-15 00:00:00

abstract：:Diabetic nerve reveals a peculiar paradox between its physiological resistance to ischemia, in conducting impulses for longer than control nerve during ischemia, and its morphological liability to more severe pathological changes of nerve fiber when rendered ischemic. These paradoxical phenomena, however, have never b...

journal_title：Journal of the neurological sciences

authors： Nukada H

更新日期：1993-11-01 00:00:00

abstract：INTRODUCTION:The NR4A2 transcription factor is important in the development, survival and phenotype of dopaminergic neurons and it is postulated as a possible biomarker for Parkinson's disease (PD). Therefore, our aim was to analyze in a sample of a Mexican population with idiopathic PD, mutations (in two hotspot mutat...

journal_title：Journal of the neurological sciences

authors： Ruiz-Sánchez E,Yescas P,Rodríguez-Violante M,Martínez-Rodríguez N,Díaz-López JN,Ochoa A,Valdes-Rojas SS,Magos-Rodríguez D,Rojas-Castañeda JC,Cervantes-Arriaga A,Canizales-Quinteros S,Rojas P

更新日期：2017-08-15 00:00:00

abstract：:Low fluidity was observed in the erythrocyte membranes of familial chorea-acanthocytosis by spin labeling with 12NS. The high content of the saturated fatty acids support the finding of low fluidity. Other lipid contents (cholesterol and phospholipids) and the cholesterol/phospholipid ratio were within normal ranges. ...

journal_title：Journal of the neurological sciences

authors： Oshima M,Osawa Y,Asano K,Saito T

更新日期：1985-05-01 00:00:00

abstract：:In 6 baboons the deep peroneal nerve was compressed for 1 hr by a weighted cord laid over the leg just above the ankle. The procedure was carried out on both sides in a single experiment. On one side the whole leg was rendered ischaemic by a cuff round the thigh which was maintained for 3 or 4 hr before and during the...

journal_title：Journal of the neurological sciences

authors： Williams IR,Jefferson D,Gilliatt RW

更新日期：1980-05-01 00:00:00

abstract：:We investigated regional cerebral blood flow (rCBF) using the [99mTc]-d,l-HMPAO technique with brain dedicated high resolution single photon emission computer tomography (SPECT) in 14 consecutive patients with amyotrophic lateral sclerosis (ALS), median age 62 years (45-77). Global CBF, expressed in % relative to the ...

journal_title：Journal of the neurological sciences

authors： Waldemar G,Vorstrup S,Jensen TS,Johnsen A,Boysen G

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Supratentorial stroke can cause conjugate eye deviation directed contralateral to the affected side (wrong-way deviation). It is rare and thought to be associated exclusively with hemorrhagic stroke. We prospectively investigated the clinical features and prognostic significance of this wrong-way...

journal_title：Journal of the neurological sciences

authors： Johkura K,Nakae Y,Yamamoto R,Mitomi M,Kudo Y

更新日期：2011-09-15 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of studies on neuropsychological complications after cardiac surgery used the raw variation of selective tests scores to define the occurrence of cognitive decline. We prospectively estimated the frequency of cognitive impairment after cardiac surgery, with a particular emphasis on p...

journal_title：Journal of the neurological sciences

authors： Di Carlo A,Perna AM,Pantoni L,Basile AM,Bonacchi M,Pracucci G,Trefoloni G,Bracco L,Sangiovanni V,Piccini C,Palmarini MF,Carbonetto F,Biondi E,Sani G,Inzitari D

更新日期：2001-07-15 00:00:00

abstract：:The findings of various studies reporting temporal changes in CSF total nitrite/nitrate (NOx) levels after subarachnoid hemorrhage (SAH) vary considerably. The study group comprised 10 patients with SAH and 10 control subjects. Total nitrite/nitrate concentration was measured by a vanadium-based assay with the colorim...

journal_title：Journal of the neurological sciences

authors： Rejdak K,Petzold A,Sharpe MA,Kay AD,Kerr M,Keir G,Thompson EJ,Giovannoni G

更新日期：2004-04-15 00:00:00

abstract：OBJECTIVES:Though much information exists about the diagnosis, treatment, and epidemiology of myasthenia gravis (MG), a comprehensive data registry and biorepository is critical to better understand disease mechanisms, treatment outcomes, and the impact of treatment strategies. We aimed to design and implement the "Exp...

journal_title：Journal of the neurological sciences

authors： Anil R,Kumar A,Alaparthi S,Sharma A,Nye JL,Roy B,O'Connor KC,Nowak RJ

更新日期：2020-07-15 00:00:00

abstract：:In this paper we review the findings of magnetic resonance imaging (MRI) in optic neuritis and visual dysfunction due to other optic neuropathies. With advances in MRI technology, it has become possible to visualise optic nerve pathology. STIR and RARE sequences, contrast-enhanced sequences, and phased array surface c...

journal_title：Journal of the neurological sciences

authors： Gass A,Moseley IF

更新日期：2000-01-15 00:00:00