Neurotransmitter amino acids in cerebrospinal fluid of patients with Parkinson's disease.

abstract：:Postnatal development of the human visual cortex is characterized by an overshooting growth pattern of its volume with a maximum at 8 postnatal months and by loss of a substantial proportion of its neurons. The highest rate of reduction in neuronal numbers is observed in layers II-IVa, with other layers showing a more...

journal_title：Journal of the neurological sciences

authors： Klekamp J,Riedel A,Harper C,Kretschmann HJ

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Platelet-leukocyte aggregations (PLA) play key roles in acute ischemic stroke (AIS) process and they are formed by the combination of P-selectin (SELP) expressed on the surface of the platelet membranes with P-selectin glycoprotein ligand-1(PSGL-1) expressed on the surface of the leukocytes. There are geneti...

journal_title：Journal of the neurological sciences

authors： Tao L,Changfu W,Linyun L,Bing M,Xiaohui H

更新日期：2016-08-15 00:00:00

abstract：:Low fluidity was observed in the erythrocyte membranes of familial chorea-acanthocytosis by spin labeling with 12NS. The high content of the saturated fatty acids support the finding of low fluidity. Other lipid contents (cholesterol and phospholipids) and the cholesterol/phospholipid ratio were within normal ranges. ...

journal_title：Journal of the neurological sciences

authors： Oshima M,Osawa Y,Asano K,Saito T

更新日期：1985-05-01 00:00:00

abstract：:The predictive validity of evoked potentials (EPs) and event-related potentials (ERPs) in multiple sclerosis (MS) has not yet been fully investigated, as only the sensitivity of these tests has sofar been reported. EPs (short, middle and long latency auditory evoked potentials and visual evoked potentials) and ERPs (v...

journal_title：Journal of the neurological sciences

authors： van Dijk JG,Jennekens-Schinkel A,Caekebeke JF,Singh A,Zwinderman AH

更新日期：1992-05-01 00:00:00

abstract：:Neocortical lesions (NLs) are an important component of multiple sclerosis (MS) pathology and may account for part of the physical and cognitive disability. Visualizing NLs of patients with MS using magnetic resonance imaging (MRI) poses several significant challenges. We optimized the inversion time (TI) of T(1)-base...

journal_title：Journal of the neurological sciences

authors： Bagnato F,Yao B,Cantor F,Merkle H,Condon E,Montequin M,Moore S,Quezado M,Tkaczyk D,McFarland H

更新日期：2009-07-15 00:00:00

abstract：:We present a patient with Parkinson's disease whose bilateral tremor transiently resolved after a unilateral left ventrolateral thalamotomy. The transient resolution of the bilateral tremor was associated with a focal thalamic lesion and a second lesion in the corpus callosum. The mechanism of this phenomenon may be r...

journal_title：Journal of the neurological sciences

authors： Greene KA,Wallace RC,Fram EK,Shetter AG,Lieberman AN

更新日期：1995-03-01 00:00:00

abstract：:Glucose-regulated protein (GRP) 94 is a member of the stress protein family, which is localized in the endoplasmic reticulum (ER). Spinal cord injury (SCI) induced ER stress that results in apoptosis. However, the role of GRP94 in injury of the central nervous system remains unknown. In this study, we performed SCI in...

journal_title：Journal of the neurological sciences

authors： Xu D,Cui S,Sun Y,Bao G,Li W,Liu W,Zhu X,Fan J,Wang Y,Cui Z

更新日期：2011-10-15 00:00:00

abstract：OBJECTIVE:To explore the role of cardiovascular risk factors and the different NOTCH-3 mutations to explain the variability observed in the clinical presentation of CADASIL. METHODS:This was a retrospective cohort study of 331 individuals, 90 were carriers of four mutations in the NOTCH3 gene. These four mutations are...

journal_title：Journal of the neurological sciences

authors： Ospina C,Arboleda-Velasquez JF,Aguirre-Acevedo DC,Zuluaga-Castaño Y,Velilla L,Garcia GP,Quiroz YT,Lopera F

更新日期：2020-12-15 00:00:00

abstract：:Although control of hypertension is established as an important factor in the primary and secondary prevention of stroke, management of blood pressure in the setting of acute ischemic stroke remains controversial. Given limited data, the general consensus is that there is no proven benefit to lowering blood pressure i...

journal_title：Journal of the neurological sciences

authors： Wityk RJ

更新日期：2007-10-15 00:00:00

abstract：:The recent history of clinical trials in ALS is marked by a great diversity in trial design. This has limited the comparability of the trial results, and has resulted in intense discussions about which parameters should or should not be evaluated when testing a new drug for ALS. This article discusses, without any cla...

journal_title：Journal of the neurological sciences

authors： Borasio GD

更新日期：1997-10-01 00:00:00

abstract：:Menkes' disease is an inherited disturbance of copper metabolism. Addition of copper to the medium of cultured fibroblasts and lymphoblasts from patients with Menkes' disease results in an increased induction of metallothionein. We investigated the metallothionein induction in response to copper and zinc in muscle cel...

journal_title：Journal of the neurological sciences

authors： Herzberg NH,Wolterman RA,van den Berg GJ,Barth PG,Bolhuis PA

更新日期：1990-12-01 00:00:00

abstract：PURPOSE:To investigate the clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-ON) in patients with varying ages of onset in China. METHODS:Patients displaying symptoms of MOG-ON were recruited from the Neuro-ophthalmology Department in the Chinese Peo...

journal_title：Journal of the neurological sciences

authors： Song H,Zhou H,Yang M,Xu Q,Sun M,Wei S

更新日期：2019-05-15 00:00:00

abstract：INTRODUCTION:Magnetization transfer ratio (MTR) histogram analysis can be used as a method for quantifying overall disease burden in MS. We studied correlations between MTR histogram and clinical parameters in MS subgroups. Contrary to earlier studies we placed special emphasis on the lower MTR range, to explore the ef...

journal_title：Journal of the neurological sciences

authors： Kalkers NF,Hintzen RQ,van Waesberghe JH,Lazeron RH,van Schijndel RA,Adèr HJ,Polman CH,Barkhof F

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Sweating on the palms of the hands and soles of the feet, so-called emotional sweating, is considered to be mediated by the limbic system, including the amygdala and anterior cingulate cortex. To reveal involvement of the limbic system in emotional sweating, we evaluated emotional sweating on the palms in pat...

journal_title：Journal of the neurological sciences

authors： Asahina M,Fujinuma Y,Yamanaka Y,Fukushima T,Katagiri A,Ito S,Kuwabara S

更新日期：2011-07-15 00:00:00

abstract：:In rabbits subjected to bicuculline (BC)- or pentylenetetrazole (PTZ)-seizures of 3 or 20 min duration or to adrenaline-induced hypertension, specific gravity (SG) was measured bilaterally in 15 regional brain areas in order to detect possible associations between the regionally limited blood-brain barrier openings du...

journal_title：Journal of the neurological sciences

authors： Nitsch C,Fujiwara K,Kuroiwa T,Klatzo I

更新日期：1984-05-01 00:00:00

abstract：:There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia (FRDA), multiple sclerosis and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species (ROS) and/or reactive nitrogen species (...

journal_title：Journal of the neurological sciences

authors： Calabrese V,Lodi R,Tonon C,D'Agata V,Sapienza M,Scapagnini G,Mangiameli A,Pennisi G,Stella AM,Butterfield DA

更新日期：2005-06-15 00:00:00

abstract：:The mirror system includes a group of neurons in the monkey cortex that discharge both when a movement is executed and when that same movement is observed. An equivalent system in humans has been proposed to mediate action and emotion understanding, being therefore related to theory of mind. Theory of mind (TOM) is th...

journal_title：Journal of the neurological sciences

authors： Alegre M,Guridi J,Artieda J

更新日期：2011-11-15 00:00:00

abstract：BACKGROUND:Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy, also called distal myopathy with rimmed vacuoles (DMRV) or hereditary inclusion body myopathy (HIBM), is a rare, progressive autosomal recessive disorder caused by mutations in the GNE gene. Here, we examined the relationship b...

journal_title：Journal of the neurological sciences

authors： Mori-Yoshimura M,Monma K,Suzuki N,Aoki M,Kumamoto T,Tanaka K,Tomimitsu H,Nakano S,Sonoo M,Shimizu J,Sugie K,Nakamura H,Oya Y,Hayashi YK,Malicdan MC,Noguchi S,Murata M,Nishino I

更新日期：2012-07-15 00:00:00

abstract：:Two transgenic strains of mutant mice lacking hypoxanthine-guanidine phosphoribosyltransferase (HPRT) activity were examined behaviorally and neurochemically for phenotypic similarity to the human Lesch-Nyhan syndrome. In this syndrome, male children markedly deficient in the enzyme HPRT develop self-mutilation and se...

journal_title：Journal of the neurological sciences

authors： Finger S,Heavens RP,Sirinathsinghji DJ,Kuehn MR,Dunnett SB

更新日期：1988-09-01 00:00:00

abstract：:Antiserum to the myelin lipid galactocerebroside (GalC) causes rapidly progressive focal demyelination when injected into guinea pig optic nerves. The capacity of anti-GalC to induce central nervous system demyelination is complement-dependent, and demyelinating activity is present in the immunoglobulin fraction of an...

journal_title：Journal of the neurological sciences

authors： Sergott RC,Brown MJ,Silberberg DH,Lisak RP

更新日期：1984-06-01 00:00:00

abstract：:The aim of the present study was to evaluate whether intravenous methylprednisolone (IVMP) pulses affect the confluence and enlargement of T2 lesions in the long term in patients with relapsing-remitting (RR) multiple sclerosis (MS). Of 88 RR MS patients, randomly assigned to regular pulses of IVMP (1 g/day for 5 days...

journal_title：Journal of the neurological sciences

authors： Zivadinov R,Zorzon M,De Masi R,Nasuelli D,Cazzato G

更新日期：2008-04-15 00:00:00

abstract：:Fatty acid compositions of erythrocyte membrane phospholipids including phosphatidylethanolamine subclasses, blood plasma and mononuclear cells of 8 patients with myotonic dystrophy (MyD) and 8 normal controls were analyzed by high performance liquid chromatography. Slight changes (decreased C18:2 and increased C16:0)...

journal_title：Journal of the neurological sciences

authors： Antoku Y,Sakai T,Goto I,Iwashita H,Kuroiwa Y

更新日期：1985-12-01 00:00:00

abstract：:Thirty-one HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 34 asymptomatic carriers were studied in order to investigate the presence of anti-lymphocyte antibodies in their sera. 32% of the patients produced allolymphocytotoxic antibodies reactive to peripheral blood lymphocytes (mainl...

journal_title：Journal of the neurological sciences

authors： Godoy AJ,Itoyama Y,Tokunaga K,Hara H,Kawaga Y,Kiyokawa H,Maeda Y,Goto I

更新日期：1994-08-01 00:00:00

abstract：:The p53-related p73 protein is an important mediator of apoptosis, development and tumorigenesis. Previously, we showed that over-expression of the p73beta isoform induced apoptosis in proliferating neuronal cells; however, the study did not address the effect of p73 in post-mitotic neurons. To address this question, ...

journal_title：Journal of the neurological sciences

authors： Jiang Y,Lo W,Akhmametyeva EM,Chang LS

更新日期：2006-01-15 00:00:00

abstract：:Fast and slow components of anterograde axoplasmic transport have been studied in the sensory fibres of the vagus nerve of alloxan-diabetic rabbits and age-matched controls by incorporation of tritiated leucine into nodose ganglion cells. The diabetic rabbits were maintained for 2 months with blood glucose levels in t...

journal_title：Journal of the neurological sciences

authors： Bajada S,Sharma AK,Thomas PK

更新日期：1980-09-01 00:00:00

abstract：:A boy, who had shown muscle weakness and hypotonia from early childhood and fiber type disproportion (FTD) with no dystrophic changes on muscle biopsy, was initially diagnosed as having congenital fiber type disproportion (CFTD). Subsequently, he developed cardiac conduction blocks. We reconsidered the diagnosis as po...

journal_title：Journal of the neurological sciences

authors： Kajino S,Ishihara K,Goto K,Ishigaki K,Noguchi S,Nonaka I,Osawa M,Nishino I,Hayashi YK

更新日期：2014-05-15 00:00:00

abstract：:The cause of amyotrophic lateral sclerosis is unknown. In this review clinical and scientific data that are pertinent to understanding this disease are reviewed. There are currently several major controversies concerning the possible role of immunological factors, genetic factors, environmental toxins, and viral infec...

journal_title：Journal of the neurological sciences

authors： Swash M,Schwartz MS

更新日期：1992-11-01 00:00:00

abstract：:Depression is frequently associated with Parkinson disease (PD) but neural basis is still unclear. In previous studies white matter changes present as signal hyperintesities on T2-wighted MRI studies (WMHs) commonly observed in older adults have been associated with depressive symptomatology. In this study we investig...

journal_title：Journal of the neurological sciences

authors： Petrovic IN,Stefanova E,Kozic D,Semnic R,Markovic V,Daragasevic NT,Kostic VS

更新日期：2012-11-15 00:00:00

abstract：:Sensory ataxia in inorganic germanium intoxication is rare. A 63-year-old housewife had taken inorganic germanium preparations at a dosage of 36 mg a day for about 6 years (total dose about 80 g). She subsequently developed difficulty in writing and gait disturbance with peripheral neuropathy and renal involvement. Ge...

journal_title：Journal of the neurological sciences

authors： Asaka T,Nitta E,Makifuchi T,Shibazaki Y,Kitamura Y,Ohara H,Matsushita K,Takamori M,Takahashi Y,Genda A

更新日期：1995-06-01 00:00:00

abstract：:Swallowing function in myasthenia gravis (MG) was investigated by videofluoroscopy (VF). A total of 23 VF examinations were performed on 11 MG patients at various time points over the exacerbation and remission stages of disease. The assessment parameters on VF examination are set as follows: bolus transport from the ...

journal_title：Journal of the neurological sciences

authors： Higo R,Nito T,Tayama N

更新日期：2005-04-15 00:00:00