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Multiple cerebral infarcts and intravascular central nervous system lymphoma: a rare but potentially treatable association.

Abstract：

:Intravascular large B-cell lymphoma (IVLBCL) is a rare lymphoproliferative disorder characterized by massive intravascular growth of lymphoma cells with a predilection for the central nervous system (CNS). Diagnosis is generally delayed by variable clinical presentation and nonspecific laboratory findings. Brain biopsy is the gold standard diagnostic test. Prognosis is poor with a high mortality rate. We report a case of "in vivo" diagnosis of IVLBCL presenting with rapidly progressive encephalopathy secondary to multiple cerebral infarcts. This case highlights IVLBCL as a possible cause of unexplained multifocal and recurrent strokes. Earlier diagnosis and consequent earlier treatment may be associated with better prognosis.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Cruto C,Taipa R,Monteiro C,Moreira I,Melo-Pires M,Correia M

doi

10.1016/j.jns.2012.10.012

subject

Has Abstract

pub_date

2013-02-15 00:00:00

pages

183-5

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(12)00569-2

journal_volume

325

pub_type

杂志文章

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