Changes in tetrodotoxin-resistant action potentials after passive transfer of myasthenia gravis patient sera.

abstract：:Ultrastructural alterations were observed in the sciatic nerve of dystrophic mice. Myelin sheaths were abnormal in shape, abruptly ceased beyond a node of Ranvier, leaving the axon naked. These changes were seen in both afferent and efferent nerve fibres. Apparent embryonal Schwann cells and Schwann cells which were a...

journal_title：Journal of the neurological sciences

authors： Okada E,Mizuhira V,Nakamura H

更新日期：1976-08-01 00:00:00

abstract：:The aim of the present study was to evaluate whether intravenous methylprednisolone (IVMP) pulses affect the confluence and enlargement of T2 lesions in the long term in patients with relapsing-remitting (RR) multiple sclerosis (MS). Of 88 RR MS patients, randomly assigned to regular pulses of IVMP (1 g/day for 5 days...

journal_title：Journal of the neurological sciences

authors： Zivadinov R,Zorzon M,De Masi R,Nasuelli D,Cazzato G

更新日期：2008-04-15 00:00:00

abstract：:Ophthalmological examination and visual evoked responses (VERs) were repeated at 6-120 (mean 46) months after the first attack of acute optic neuritis in 80 patients who had abnormal VERs in 98 symptomatic eyes at the initial examination. The wide field VER returned to within the normal range in 19/98 (19%) symptomati...

journal_title：Journal of the neurological sciences

authors： Hely MA,McManis PG,Walsh JC,McLeod JG

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Olfactory identification impairment in amnestic mild cognitive impairment (aMCI) patients is well documented and considered to be caused by underlying Alzheimer's disease (AD) pathology, contrasting with less clear evidence in non-amnestic MCI (naMCI). The aim was to (a) compare the degree of olfactory ident...

journal_title：Journal of the neurological sciences

authors： Vyhnalek M,Magerova H,Andel R,Nikolai T,Kadlecova A,Laczo J,Hort J

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:The mechanisms for improved cognitive function post-bariatric surgery are not well understood. Markers of kidney and liver function (i.e., cystatin C and alkaline phosphatase (ALP)) are elevated in obese individuals and associated with poor neurocognitive outcomes in other samples. Bariatric surgery can impr...

journal_title：Journal of the neurological sciences

authors： Alosco ML,Spitznagel MB,Strain G,Devlin M,Cohen R,Crosby RD,Mitchell JE,Gunstad J

更新日期：2014-10-15 00:00:00

abstract：:Mitochondrial dysfunction aggravates ischemic neuronal injury through activation of various pathophysiological and molecular mechanisms. Ischemic neuronal injury is particularly intensified during reperfusion due to impairment of mitochondrial function. Mitochondrial mutilation instigates alterations in calcium homeos...

journal_title：Journal of the neurological sciences

authors： Bakthavachalam P,Shanmugam PST

更新日期：2017-04-15 00:00:00

abstract：:We studied the production within the CNS of anti-HIV antibodies, of non-specific IgG, and the presence of HIV antigens in the serum and CSF of 28 HIV infected patients belonging to group IV in the Center for Disease Control classification. CSF and serum were diluted under optimal conditions to equalize their IgG conte...

journal_title：Journal of the neurological sciences

authors： Lolli F,Colao MG,De Maio E,Di Pietro M,Galli E,Grippo A,Mazzotta F,Pinto F

更新日期：1990-11-01 00:00:00

abstract：:A point mutation at codon 210 (GTT to ATT) of the prion protein gene on chromosome 20 was found in a 48-year-old CJD-affected woman of a Chinese family. This affected woman had an early onset and long-duration form of CJD. Serial magnetic resonance image (MRI) analysis of this woman showed severe brain atrophy, promin...

journal_title：Journal of the neurological sciences

authors： Shyu WC,Hsu YD,Kao MC,Tsao WL

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:Intracranial bleeding and inflammatory reactions are common consequences of traumatic brain injury (TBI). Neutrophil gelatinase-associated lipocalin (NGAL), an iron-handling and acute phase protein, may participate in the pathogenesis of TBI. Therefore, we hypothesize that NGAL may be of high diagnostic and the...

journal_title：Journal of the neurological sciences

authors： Zhao J,Chen H,Zhang M,Zhang Y,Qian C,Liu Y,He S,Zou Y,Liu H

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:There are conflicting data on the relationship between peripheral arterial disease (PAD) as defined by an ankle-brachial index (ABI) of <0.9 and stroke risk, and these prior data have largely focused on a single race or gender. Furthermore, the association between subsequent ABIs above the established 0.9 th...

journal_title：Journal of the neurological sciences

authors： Ovbiagele B

更新日期：2009-01-15 00:00:00

abstract：BACKGROUND AND PURPOSE:The progression of cognitive deterioration in patients with Alzheimer's disease (AD) is considerably variable. The ability to predict the progression rate is important for clinicians to treat and manage patients with AD. We examined the possible relationship between the rate of cognitive deterior...

journal_title：Journal of the neurological sciences

authors： Hanyu H,Sato T,Hirao K,Kanetaka H,Iwamoto T,Koizumi K

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:In the diagnostic work-up of young stroke patients angiography is still considered as mandatory to identify otherwise undetected causes of stroke. We hypothesized that stroke cause is more heterogeneous among patients with a territorial infarct, whereas in lacunar stroke it is generally small vessel disease....

journal_title：Journal of the neurological sciences

authors： de Jong S,Lodder J,Luijckx GJ

更新日期：2004-07-15 00:00:00

abstract：:We report three related patients with autosomal dominant hereditary motor and sensory neuropathy (HMSN). An unusual and characteristic feature was calf enlargement, caused by muscle fiber hypertrophy predominantly of type 1 fibers. None of the family members showed atrophy of the legs. Sural nerve pathology disclosed ...

journal_title：Journal of the neurological sciences

authors： Sakashita Y,Sakato S,Komai K,Takamori M

更新日期：1992-11-01 00:00:00

abstract：:Cutaneomuscular reflexes have been recorded from the first dorsal interosseous muscle during a sustained abduction of the index finger of 20 subjects (25 recordings) following stimulation of the digital nerves at the following frequencies: 2 Hz, 3 Hz, 5 Hz, 7 Hz and 9 Hz, presented in random order. Five hundred stimul...

journal_title：Journal of the neurological sciences

authors： Harrison LM,Norton JA,Stephens JA

更新日期：2000-08-01 00:00:00

abstract：:Previously, we demonstrated that neuronal nitric oxide synthase (nNOS) is activated and promotes muscle atrophy in skeletal muscle during tail suspension, a model of unloading and denervation. Here, we examined patients with amyotrophic lateral sclerosis (ALS) and mutant (H46R) SOD1 transgenic (Tg) mice model using im...

journal_title：Journal of the neurological sciences

authors： Suzuki N,Mizuno H,Warita H,Takeda S,Itoyama Y,Aoki M

更新日期：2010-07-15 00:00:00

abstract：:Prefrontal corticofugal systems, as studied with anterograde HRP histochemistry, revealed projections to preoculomotor and oculomotor centers in the diencephalon and brainstem which may underlie direct cortical influence on eye movement. Because of the location of these preoculomotor trajectories, stimulation and lesi...

journal_title：Journal of the neurological sciences

authors： Leichnetz GR

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Molecular diagnosis of hereditary spastic paraplegias (HSP) is a difficult task due to great clinical and genetic heterogeneity. We aimed to characterize clinical and molecular findings of HSP families from Rio Grande do Sul, Brazil; and to evaluate the diagnostic yield of a next-generation sequencing (NGS) ...

journal_title：Journal of the neurological sciences

authors： Burguez D,Polese-Bonatto M,Scudeiro LAJ,Björkhem I,Schöls L,Jardim LB,Matte U,Saraiva-Pereira ML,Siebert M,Saute JAM

更新日期：2017-12-15 00:00:00

abstract：:Hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) is a rare, life-threatening disease, caused by point mutations in the transthyretin gene. It is a heterogeneous, multisystem disease with rapidly progressing polyneuropathy (including sensory, motor, and autonomic impairments) and cardiac dysfunction. M...

journal_title：Journal of the neurological sciences

authors： Dyck PJB,González-Duarte A,Obici L,Polydefkis M,Wiesman JF,Antonino I,Litchy WJ,Dyck PJ

更新日期：2019-10-15 00:00:00

abstract：:Long-term effects of MPTP on striatal dopamine (DA) content and the influence of aging on the recovery were investigated in mice. Male C57BL/6J mice, young (2-month-old) and mature (10-month-old), were used. Two different dosage schedules of MPTP, i.e., 4 doses subcutaneous injections of 20 mg/kg each, and 4 doses sub...

journal_title：Journal of the neurological sciences

authors： Saitoh T,Niijima K,Mizuno Y

更新日期：1987-02-01 00:00:00

abstract：:Bacillus Calmette-Guérin (BCG) and Mycobacterium avium subspecies paratuberculosis (MAP) have been associated with multiple sclerosis (MS). Clinical data indicates that BCG vaccination exerts anti-inflammatory effects in MS; conversely, MAP is thought to be one of the possible infectious factors responsible of MS thro...

journal_title：Journal of the neurological sciences

authors： Cossu D,Mameli G,Masala S,Cocco E,Frau J,Marrosu MG,Sechi LA

更新日期：2014-12-15 00:00:00

abstract：:A monoclonal antibody (MAb) raised against central nervous system (CNS) myelin (212) and a MAb (308) raised against brain with Semliki Forest virus (SFV) were both found to react against the same CNS glycolipids. Both these MAbs were also found to react strongly with SFV and against certain brain glycolipid fractions ...

journal_title：Journal of the neurological sciences

authors： Khalili-Shirazi A,Gregson N,Webb HE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Data on the determinants and outcome of ischemic stroke (IS) from the Arabian Gulf countries (AGC) are still scanty. The aim of this study was to characterize IS in six large stroke centers on the Arabian peninsula. METHODS:IS subtypes were evaluated in four AGC from January 2006 to December 2007 in a large...

journal_title：Journal of the neurological sciences

authors： Deleu D,Inshasi J,Akhtar N,Ali J,Vurgese T,Ali S,Rajan M,AlMutairy M,Zayed A,Paulose G,Nouri K,Thussu A,Miyares FR,Abdeen T,AlHail H,Alshubaili A,Mahmoud H

更新日期：2011-01-15 00:00:00

abstract：:Churg-Strauss syndrome (CSS) is a rare systemic vasculitis, almost invariably accompanied by asthma, nasal polyposis, paranasal sinus abnormalities, and increased peripheral blood eosinophil count. Neurological involvement as peripheral neuropathy is a common feature, whereas cerebral involvement is extremely rare. He...

journal_title：Journal of the neurological sciences

authors： Mencacci NE,Bersano A,Cinnante CM,Ciammola A,Corti S,Meroni PL,Silani V

更新日期：2011-02-15 00:00:00

abstract：:This study describes the electrophysiological responses of endoneurial preparations derived from rat sciatic nerve to acute hypoxia in vitro. Preparations from control rats exhibited a 40% decline in compound action potential (CAP) amplitude after 40 min exposure to medium gassed with 8% O2. In preparations from 4 wee...

journal_title：Journal of the neurological sciences

authors： Calcutt NA,Carrington AL,Ettlinger CB,Tomlinson DR

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Single cases with hemispheric, cortical or subcortical, ischemic lesions presenting with rotational vertigo (RV), that challenge the notion of infratentorial or peripheral generation of RV have been published, but the incidence of this symptom in a larger series is unknown. The aim of this study was to inves...

journal_title：Journal of the neurological sciences

authors： Anagnostou E,Spengos K,Vassilopoulou S,Paraskevas GP,Zis V,Vassilopoulos D

更新日期：2010-03-15 00:00:00

abstract：:The specificity of anatomo-clinical observations were investigated on 776 out of 982 consecutive persons hospitalized at the University Psychiatric Clinic of Geneva. Discriminant function analysis shows that most of the anatomical classes (no dementia, senile dementia, Alzheimerized senile dementia and Alzheimer's pre...

journal_title：Journal of the neurological sciences

authors： Todorov AB,Go RC,Constantinidis J,Elston RC

更新日期：1975-09-01 00:00:00

abstract：:Hereditary spongiform dystrophy in young children is characterised by macrocephaly with spasticity, convulsions and ultimately a decerebrate state and diffuse electroencephalographic changes. Histological examination of the brain remains essential for its diagnosis. A review of the ultrastructural studies reported by ...

journal_title：Journal of the neurological sciences

authors： Mirimanoff P

更新日期：1976-06-01 00:00:00

abstract：:The effects of synergist tenotomy have been studied on rat soleus muscles after denervation and after interference with sciatic axoplasmic flow with colchicine. The results suggest that neural, as well as muscular, factors cause compensatory hypertrophy (CH) of soleus. The myogenic factor may be mild depolarization of...

journal_title：Journal of the neurological sciences

authors： Hofmann WW

更新日期：1980-03-01 00:00:00

abstract：:The incidence of carpal tunnel syndrome is increased during pregnancy. The common conventional therapeutic approach is conservative, as symptoms usually abate after delivery. We describe our experience with 65 hands (50 patients), who were treated initially by a conservative approach and later, when required, surgical...

journal_title：Journal of the neurological sciences

authors： Stahl S,Blumenfeld Z,Yarnitsky D

更新日期：1996-03-01 00:00:00

abstract：:A case of demyelinating polyneuropathy is reported which was clinically and pathologically indistinguishable from the Guillain-Barré syndrome, with the exception that the symptoms progressed steadily for 7 months. Pathologically, the peripheral nerves and intraspinal roots showed selective demyelination with axonal sp...

journal_title：Journal of the neurological sciences

authors： Torvik A,Lundar T

更新日期：1977-05-01 00:00:00