当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > Prevalence and pattern of cognitive impairment in systemic lupus erythematosus patients with and without overt neuropsychiatric manifestations.

Prevalence and pattern of cognitive impairment in systemic lupus erythematosus patients with and without overt neuropsychiatric manifestations.

Abstract：

:The prevalence and pattern of cognitive impairment in systemic lupus erythematosus (SLE) patients with (NPSLE) and without (nSLE) overt neuropsychiatric manifestations were investigated. Fifty-two nSLE patients, 23 NPSLE patients and 27 healthy controls were evaluated with a battery of standardized neuropsychological and psychological tests. Disease duration, disease activity index, and current corticosteroid therapy were collected. Cognitive impairment was identified in 14 (26.9%) and in 12 (52.2%) of subjects with nSLE and NPSLE, respectively. Both SLE groups showed a significant impairment compared with controls on tasks assessing verbal and non-verbal long-term memory, and visuoconstructional abilities. In addition, NPSLE patients reported worse performances than both nSLE patients and controls on task evaluating short-term visuospatial memory. NPSLE subjects were significantly more anxious and depressed compared to both nSLE subjects and controls. By multivariate analysis, only depression levels, among clinical variables, significantly predicted cognitive performance. This study shows that cognitive impairment occurs frequently in both nSLE and NPSLE subjects. The higher frequency in NPSLE may be related to coexisting depressive disturbances.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Monastero R,Bettini P,Del Zotto E,Cottini E,Tincani A,Balestrieri G,Cattaneo R,Camarda R,Vignolo LA,Padovani A

doi

10.1016/s0022-510x(00)00492-5

subject

Has Abstract

pub_date

2001-02-15 00:00:00

pages

33-9

issue

1

eissn

0022-510X

issn

1878-5883

pii

S0022510X00004925

journal_volume

184

pub_type

临床试验,杂志文章

相关文献

JOURNAL OF THE NEUROLOGICAL SCIENCES文献大全
  • Effect of partial denervation on motor units in the ageing rat medial gastrocnemius.

    abstract：:The ageing neuromuscular system is thought to undergo a continual process of reorganization as motoneurones are lost and surviving motor nerves reinnervate neighbouring denervated muscle fibres. However, the extent to which collateral reinnervation is able to compensate for neural deficits in the ageing individual is ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(92)90148-e

    authors： Einsiedel LJ,Luff AR

    更新日期：1992-10-01 00:00:00

  • Predisposing role of vitamin D receptor (VDR) polymorphisms in the development of multiple sclerosis: A case-control study.

    abstract：:Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) with a complex etiology. Given the Vitamin D receptor (VDR) gene, it is considered an outstanding risk component associated with MS. The aim of the present study has been to explore and e...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.05.053

    authors： Abdollahzadeh R,Fard MS,Rahmani F,Moloudi K,Kalani BS,Azarnezhad A

    更新日期：2016-08-15 00:00:00

  • Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.

    abstract：:Protein stabilization and oligonucleotide therapies are being tested in transthyretin amyloid polyneuropathy (TTR FAP) trials. From retrospective analysis of 97 untreated TTR FAP patients, we test the adequacy of Neuropathy Impairment Score+7 tests (NIS+7) and modifications to comprehensively score impairments for use...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.06.041

    authors： Suanprasert N,Berk JL,Benson MD,Dyck PJ,Klein CJ,Gollob JA,Bettencourt BR,Karsten V,Dyck PJ

    更新日期：2014-09-15 00:00:00

  • The small sodium-channel blocking factor in the cerebrospinal fluid of multiple sclerosis patients is probably an oligopeptide.

    abstract：:An endogenous factor that is able to reduce the fast transient sodium current of excitable cells has been reported to exist in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients. This was confirmed with nine clinically definite MS patients in the acute relapse. In order to purify and chemically identify...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(99)00285-3

    authors： Aulkemeyer P,Hausner G,Brinkmeier H,Weber F,Würz A,Heidenreich F,Rüdel R

    更新日期：2000-01-01 00:00:00

  • Unlike myofibers, neuromuscular junctions remain stable during prolonged muscle unloading.

    abstract：:This study assessed the effect of muscle unloading on the neuromuscular system. Sixteen male Fischer 344 rats were randomly assigned to either a hindlimb suspension (unloaded) or control group (N=8/group) for 16 days. Following this intervention period, pre- and postsynaptic features of the neuromuscular junctions (NM...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(02)00455-0

    authors： Deschenes MR,Will KM,Booth FW,Gordon SE

    更新日期：2003-06-15 00:00:00

  • Cerebrovascular reactivity over time course in healthy subjects.

    abstract：INTRODUCTION:Cerebrovascular reactivity (CVR) reflects the compensatory dilatory capacity of cerebral arterioles to a dilatory stimulus and is an important mechanism for maintaining constant cerebral blood flow. Many pathological conditions are associated with an impaired CVR thus contributing to a higher risk of cereb...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2006.06.009

    authors： Schwertfeger N,Neu P,Schlattmann P,Lemke H,Heuser I,Bajbouj M

    更新日期：2006-11-15 00:00:00

  • Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis.

    abstract：:Multiple sclerosis is an inflammatory disease of the central nervous system (CNS) which includes a neurodegenerative component. Brain derived neurotrophic factor (BDNF) is a neuroprotective agent which might be useful in preventing neurodegeneration but its application has been limited because the blood brain barrier ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2008.02.011

    authors： Makar TK,Trisler D,Sura KT,Sultana S,Patel N,Bever CT

    更新日期：2008-07-15 00:00:00

  • Serum levels of vitamin A in Parkinson's disease.

    abstract：:To elucidate a possible role of vitamin A in the pathogenesis of Parkinson's disease (PD) we compared serum levels of retinol (vitamin A), measured by HPLC, and the vitamin A/retinol binding protein (RBP) ratio of 42 PD patients (22 males and 20 females, mean age 67.3 +/- 1.34 years) and their respective spouses as co...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(92)90114-z

    authors： Jiménez-Jiménez FJ,Molina JA,Fernández-Calle P,Vázquez A,Pondal M,del Ser T,Gómez-Pastor A,Codoceo R

    更新日期：1992-08-01 00:00:00

  • Gait analysis in a component timed-up-and-go test using a smartphone application.

    abstract：BACKGROUND:The timed-up-and-go test (TUG) is a popular test for mobility, but it only measures the total time to complete tasks. Recent advances in smartphone technology enables measuring respective times of 6 components in the test (Stand, Go, Turn1, Come, Turns and Sit). We examined availability of these data for ass...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2019.01.023

    authors： Ishikawa M,Yamada S,Yamamoto K,Aoyagi Y

    更新日期：2019-03-15 00:00:00

  • White matter changes mimicking a leukodystrophy in a patient with Mucopolysaccharidosis: characterization by MRI.

    abstract：:Mucopolysaccharidosis (MPS) type I (alpha-iduronidase deficiency) is characterized by storage and massive urinary excretion of dermatan sulfate and heparan sulfate; it may be distinguished into three different subtypes based on age at onset and severity of the clinical symptoms. We report on progressive white matter i...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(02)00014-x

    authors： Barone R,Parano E,Trifiletti RR,Fiumara A,Pavone P

    更新日期：2002-03-30 00:00:00

  • Magnetization transfer ratio in cerebral white matter lesions of Binswanger's disease.

    abstract：:We measured the magnetization transfer (MT) ratios in white matter lesions of Binswanger's disease (BD) and compared them with BD and with similar-appearing changes in non-demented elderly subjects and cerebral infarction. Four subject groups were studied: 30 patients with BD and periventricular hyperintensity (PVH) o...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(99)00122-7

    authors： Hanyu H,Asano T,Sakurai H,Iwamoto T,Takasaki M,Shindo H,Abe K

    更新日期：1999-07-01 00:00:00

  • Adoptive transfer of experimental allergic encephalomyelitis with lectin-activated spleen cells.

    abstract：:Adoptive transfer of experimental allergic encephalomyelitis (EAE) was achieved in Lewis rats using spleen cells incubated in vitro with various lectins. When stimulated with concanavalin A (Con A), its derivative succinyl-Con A, Lens culinaris or Pisum sativum agglutinin, spleen cells obtained from rats immunized wit...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(84)90014-5

    authors： Takenaka A,Kaneko K,Mori R,Itoyama Y

    更新日期：1984-11-01 00:00:00

  • Increased interhemispheric resting-state functional connectivity in paroxysmal kinesigenic dyskinesia: a resting-state fMRI study.

    abstract：PURPOSE:Paroxysmal kinesigenic dyskinesia (PKD) is a rare movement disorder. The underlying neural mechanisms have not been fully understood. This study aimed to examine the alteration of resting-state functional connectivity (RSFC) between interhemispheric homotopic regions in PKD using a technique called "voxel-mirro...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.02.046

    authors： Ren J,Lei D,Yang T,An D,Xiao F,Li L,Huang X,Gong Q,Zhou D

    更新日期：2015-04-15 00:00:00

  • Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.

    abstract：OBJECT:The purpose of this study was to determine the effects of diazoxide on apoptosis and the relative mechanisms in a model of brain injury induced by cerebral ischemia/reperfusion (I/R) during deep hypothermia. METHODS:Three-week-old Sprague-Dawley male rats were randomly and equitably divided into sham-operated g...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2007.10.029

    authors： He X,Mo X,Gu H,Chen F,Gu Q,Peng W,Qi J,Shen L,Sun J,Zhang R,Kj Y

    更新日期：2008-05-15 00:00:00

  • Further studies of mitochondrial and lipid storage myopathies.

    abstract：:Further observations on a family with facioscapulohumeral (FSH) muscular dystrophy due to mitochondrial myopathy, and on a case with lipid storage myopathy are reported. One member of the family with FSH muscular dystrophy died due to a viral pneumonia, during which she developed gross hyperlacticacidaemia and acidosi...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(78)90003-5

    authors： Bradley WG,Tomlinson BE,Hardy M

    更新日期：1978-02-01 00:00:00

  • Ubiquitin-positive inclusion in anterior horn cells in subgroups of motor neuron diseases: a comparative study of adult-onset amyotrophic lateral sclerosis, juvenile amyotrophic lateral sclerosis and Werdnig-Hoffmann disease.

    abstract：:This report concerns the expression of ubiquitin in anterior horn cells of various subgroups of adult and infantile motor neuron disease (MNDs); immunohistochemical techniques were employed. Ubiquitin-positive skein-like inclusions (SLIs) were found in all cases of adult-onset amyotrophic lateral sclerosis (ALS), incl...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(93)90226-o

    authors： Matsumoto S,Goto S,Kusaka H,Imai T,Murakami N,Hashizume Y,Okazaki H,Hirano A

    更新日期：1993-04-01 00:00:00

  • A census of movement disorders at a Thai university hospital.

    abstract：:There is little information available on the number of patients with movement disorders seen by physicians in Thailand. The authors reviewed the medical records of all movement disorders patients seen at the Chulalongkorn Comprehensive Movement Disorders Center (CUMDS) in Bangkok, Thailand over a 4.5-year period to de...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.11.010

    authors： Bhidayasiri R,Saksornchai K,Kaewwilai L,Phanthumchinda K

    更新日期：2011-02-15 00:00:00

  • Neurophysiological evidence of spared upper motor conduction fibers in clinically complete spinal cord injury: discomplete SCI in rats.

    abstract：:Motor evoked potentials (MEP) were recorded and characterized by epidural electrodes (scMEP) and extracellular microelectrodes (exMEP) on T(13) level from 10 normal rats and 40 rats with chronic spinal cord injury (SCI). The spinal cord of 40 anesthetized rats were injured with various severity (sham, 35, 70, and 100 ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(01)00545-7

    authors： Yu K,Rong W,Li J,Jia L,Yuan W,Yie X,Shi Z

    更新日期：2001-08-15 00:00:00

  • Clinical and laboratory findings with giant cell arteritis.

    abstract：:Out of 66 patients who were diagnosed as suffering from polymyalgia rheumatica (PMR; n = 40), temporal arteritis (AT; n = 14) or both (n = 12) in a 6.5 year period (incidence 3.4/100,000 per year), 9 died and 49 were followed up for an average period of 28 months. Exacerbations of the illness (n = 24) and complication...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/0022-510x(92)90105-t

    authors： Berlit P

    更新日期：1992-08-01 00:00:00

  • Cerebellar decompensation following a stroke in contralateral posterior parietal cortex.

    abstract：:We describe here a patient who exhibited cerebellar hypermetria on the left side following a cerebellar ischemia in left cerebellar hemisphere. She subsequently recovered clinically. However, twenty months after cerebellar ischemia, cerebellar symptoms reappeared suddenly. Moreover, kinematic and electromyographic (EM...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(99)00152-5

    authors： Manto M,Setta F,Jacquy J,Godaux E

    更新日期：1999-08-15 00:00:00

  • Gangliosides containing glucosamine and galactosamine in transformed Tay-Sachs disease and normal human brain cell lines.

    abstract：:Human SV-40 transformed brain cell lines derived from Tay-Sachs disease (TSD) and normal fetal cerebra were grown in culture and analyzed for their ganglioside content. Both the TSD and normal cells contained GM3, GM2, and a novel triheoxyl N-acetylglucosamine-containing ganglioside. In order to increase tumorigenicit...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(80)80013-x

    authors： Schneck L,Hoffman LM,Brooks SE,Amsterdam D

    更新日期：1980-02-01 00:00:00

  • No association between APOE ε 4 allele and multiple sclerosis susceptibility: a meta-analysis from 5472 cases and 4727 controls.

    abstract：BACKGROUND:Apolipoprotein E (APOE) gene ε4, 2 alleles have been reported to be associated with multiple sclerosis (MS), but results were conflicting. In order to derive a more precise estimation of the associations, a meta-analysis was performed. METHODS:The PubMed, EBSCO and BIOSIS databases were searched to identify...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jns.2011.05.040

    authors： Xuan C,Zhang BB,Li M,Deng KF,Yang T,Zhang XE

    更新日期：2011-09-15 00:00:00

  • The numbers of limb motor neurons in the human lumbosacral cord throughout life.

    abstract：:Forty-seven spinal cords from subjects between 13 and 95 years of age have been examined; in the majority death occurred suddenly or rapidly from a state of previous good health. The limb motor neurons in the lumbospinal segments have been estimated by counting nucleoli in characeteristic cells in every fifth group of...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(77)90069-7

    authors： Tomlinson BE,Irving D

    更新日期：1977-11-01 00:00:00

  • Prevalence of MR imaging abnormalities in vitamin B12 deficiency patients presenting with clinical features of subacute combined degeneration of the spinal cord.

    abstract：BACKGROUND AND AIMS:Subacute combined degeneration (SACD) of the spinal cord, characterized by degeneration of lateral and posterior columns, is often found in vitamin B12 deficiency. Our aim was to look for sensitivity of imaging in depicting the spinal cord abnormality in vitamin B12 deficient patients and to find an...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.05.020

    authors： Jain KK,Malhotra HS,Garg RK,Gupta PK,Roy B,Gupta RK

    更新日期：2014-07-15 00:00:00

  • Stroke admission and case-fatality in an urban medical unit in sub-Saharan Africa: a fourteen year trend study from 1999 to 2012.

    abstract：BACKGROUND:Data on recent stroke trends in the context of rapidly deteriorating risk profile of populations within Africa is very limited. We investigated the admission trend for stroke and related outcomes in a major referral hospital in Cameroon. METHODS:Admission and discharge registries, and patient files for the ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.02.002

    authors： Lekoubou A,Nkoke C,Dzudie A,Kengne AP

    更新日期：2015-03-15 00:00:00

  • Quality of life and non-motor symptoms in Parkinson's disease patients with subthreshold depression.

    abstract：BACKGROUND:The role of subthreshold depression (subD) in Parkinson's Disease (PD) is not clear. The present study aimed to compare the quality of life (QoL) in PD patients with subD vs patients with no depressive disorder (nonD). Factors related to subD were identified. MATERIAL AND METHODS:PD patients and controls re...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2020.117109

    authors： Santos-García D,de Deus Fonticoba T,Suárez Castro E,Aneiros Díaz A,Cores Bartolomé C,Feal Panceiras MJ,Paz González JM,Valdés Aymerich L,García Moreno JM,Blázquez Estrada M,Jesús S,Mir P,Aguilar M,Planellas LL,García Caldente

    更新日期：2020-11-15 00:00:00

  • A morphometric analysis of human muscle fibers with relation to fiber types and adaptations to exercise.

    abstract：:Muscle biopsies were obtained from the vastus lateralis of 14 male subjects: 3 long distance runners, 2 world class power lifters and 9 active, although not highly trained, individuals used as controls. The fibers were investigated by electron microscopy and the mitochondrial volume percent, lipid volume percent and Z...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(81)90076-9

    authors： Prince FP,Hikida RS,Hagerman FC,Staron RS,Allen WH

    更新日期：1981-02-01 00:00:00

  • PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden.

    abstract：BACKGROUND:Genetic variants in Phosphodiesterase 4D (PDE4D) and 5-lipoxygenase activating protein (ALOX5AP) have been shown to confer risk of Ischemic Cerebrovascular Disease (ICVD) in Iceland. We investigated whether these variants associate with ICVD in Sweden. METHODS:Previously published PDE4D and ALOX5AP gene var...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2007.06.042

    authors： Kostulas K,Gretarsdottir S,Kostulas V,Manolescu A,Helgadottir A,Thorleifsson G,Gudmundsson LJ,Thorsteinsdottir U,Gulcher JR,Stefansson K,Hillert J

    更新日期：2007-12-15 00:00:00

  • Delays in door-to-needle time for acute ischemic stroke in the emergency department: A comprehensive stroke center experience.

    abstract：BACKGROUND:Current American Stroke Association guidelines recommend initiating intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) within 60min of patient arrival, given the benefits of IVT for AIS are time dependent. This study aimed to identify the delaying factors in door-to-needle time (DTN) in the emerg...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.03.003

    authors： Mowla A,Doyle J,Lail NS,Rajabzadeh-Oghaz H,Deline C,Shirani P,Ching M,Crumlish A,Steck DA,Janicke D,Levy EI,Sawyer RN

    更新日期：2017-05-15 00:00:00

  • Successful intra-arterial thrombolysis beyond the accepted 6-hour time window in two young patients.

    abstract：:Two young women with ischemic stroke successfully underwent intra-arterial thrombolysis (IAT) 10 and 11h, respectively after stroke onset. A 23-year-old (case 1) and a 22-year-old woman (case 2) who developed severe neurological deficits (NIHSS 20 and 13, respectively) were presented to our hospital 9h after onset of ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2009.10.003

    authors： Coster S,van Dijk LC,Treurniet FE,van Overhagen H,van Woerkom TC

    更新日期：2010-01-15 00:00:00