Abstract:
BACKGROUND:This prospective and controlled histologic study evaluates the impact of smoking on bone-to-implant contact, the bone density in the threaded area, and the bone density outside the threaded area around microimplants with anodized surface retrieved from human jaws. METHODS:A total of 24 subjects (mean age 51.32 + or - 7.5 years) were divided in two groups: smokers (n = 13 subjects) and non-smokers (n = 11 subjects). Each subject received one microimplant with oxidized surface during conventional mandible or maxilla implant surgery. After 8 weeks, the microimplants and the surrounding tissue were removed and prepared for histomorphometric analysis. RESULTS:Three microimplants placed in smokers showed no osseointegration. The newly formed bone showed early stages of maturation, mainly in the non-smokers. Marginal bone loss, gap, and fibrous tissue were present around implants retrieved from smokers. Histometric evaluation indicated that the mean bone-to-implant contact ranged between 25.97% + or - 9.02% and 40.01% + or - 12.98% for smokers and non-smokers, respectively (P <0.001). Smokers presented 28.17% + or - 10.32% of bone density in the threaded area, whereas non-smokers showed 46.34% + or - 19.12%. The mean of bone density outside the threaded area ranged between 18.76% and 25.11% for smokers and non-smokers, respectively (P >0.05). CONCLUSION:The present data obtained in human subjects confirm that smoking has a detrimental effect on early bone tissue response around oxidized implant surfaces.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Shibli JA,Piattelli A,Iezzi G,Cardoso LA,Onuma T,de Carvalho PS,Susana d,Ferrari DS,Mangano C,Zenóbio EGdoi
10.1902/jop.2010.090493subject
Has Abstractpub_date
2010-04-01 00:00:00pages
575-83issue
4eissn
0022-3492issn
1943-3670journal_volume
81pub_type
杂志文章abstract:BACKGROUND:Of the many forms of periodontal disease, refractory periodontal diseases are the least characterized. They are defined as the continued degeneration of the periodontium despite adequate management. This has led to the suggestion that there may be a systemic component that is a contributing factor to the dev...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050108
更新日期:2006-02-01 00:00:00
abstract::The purpose of this study was to evaluate interexaminer and intraexaminer probing force variations in various regions of the mouth and adjacent to different tooth surfaces. Fifty-eight dental clinicians composed of 13 periodontists, 15 general dentists, 15 hygienists and 15 senior dental students probed the facial sur...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.8.488
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:Periodontitis and osteoporosis are characterized by the loss of bone mass. Osteocalcin levels have been postulated as a marker of inhibition of bone formation. The aim of the present study was to assess plasma, saliva, and gingival crevicular fluid (GCF) levels of osteocalcin and correlate them with periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.4.513
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:In an attempt to evaluate the influence of cyclosporin A (CsA) on fibroblast metabolism, the phospholipase C beta1, (PLC beta1) nuclear expression was evaluated in fibroblasts from heart transplantation patients treated with CsA who exhibited gingival overgrowth (GO) and from controls. METHODS:PLC beta1 was...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.11.1722
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Heme oxygenase (HO)-1 is a stress-inducible protein that confers cytoprotection, but its role in gingiva during cyclosporin A (CsA) therapy is unknown. We used in vivo and in vitro models to investigate the expression of mRNA and protein for HO-1 in gingiva upon CsA treatment. METHODS:Twenty-six male Spragu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.080160
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Little is known regarding the interaction of dental implant surface nanotubes and oral soft and hard tissues. The purpose of this study was to evaluate both histologically and radiographically the qualitative and quantitative effects of dental implant surface nanotubes on hard and soft tissue in a canine mod...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.18-0205
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Bisphosphonates (BPs) are an important group of drugs used for the treatment of metabolic and oncologic pathologies involving the skeletal system. Osteonecrosis of the jaw (ONJ) is a complication observed in patients using oral or intravenous (IV) BPs. It was suggested that all patients undergoing BP therapy...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2009.090587
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Most studies comparing prevalence of periodontal disease and risk factors by using partial protocols were performed in adult populations, with several studies being conducted in clinical settings. The aim of this study is to assess the accuracy of partial protocols in estimating the prevalence of periodontal...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.110250
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:It has been shown that lowering the concentration of chlorhexidine (CHX) in mouthrinses from 0.2% to 0.12% does not adversely affect inhibition of plaque accumulation. The aim of this study was to evaluate the inhibition of plaque growth by 2 commercially available mouthrinses used according to the manufactu...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.2.214
更新日期:2003-02-01 00:00:00
abstract::Repeated measurements of attachment level appear to be important assessments in periodontal clinical trials, yet the lack of reliability for this assessment creates measurement error which in turn demands increased sample sizes or reduces the power of the test. A plastic occlusal stent has been developed as a fixed re...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.2.115
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:In Alabama, low birth weight (LBW) infants are about 20 times more likely to die before their first birthday compared to normal birth weight infants. While the rate of LBW has been consistently higher among African Americans compared to whites, there has been a gradual increase in LBW for both African Americ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.11.1491
更新日期:2001-11-01 00:00:00
abstract::The analgesic activity of single doses of meclofenamate (100 mg) was compared to aspirin (500 mg) and to placebo on 99 outpatients with moderate to severe pain following periodontal surgery under double-blind conditions. Pain intensity differences scores (PID) at the first, second, and third hour after the ingestion o...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1992.63.3.166
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:Fluoxetine, a selective serotonin reuptake inhibitor, has been reported to reduce periodontal disease severity in a rat ligature-induced periodontitis model. The objective of the present study is to investigate the influence of fluoxetine intake on periodontal parameters in patients with periodontitis with c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.140706
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Microarray analysis of local and peripheral cells in subjects with immune-inflammatory diseases may identify candidate genes associated with these diseases. The present study identified differentially expressed genes in peripheral blood mononuclear cells (PBMCs) from subjects with untreated localized aggress...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070309
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Relative few reports exist concerning healing of laser created osteotomies over an extended period of time. The purpose of this study was to evaluate long-term healing, from 21 to 63 days, of osteotomy defects in the rat tibia created with the Nd:YAG and CO2 in the presence of a surface cooling spray of air/...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.2.174
更新日期:2001-02-01 00:00:00
abstract::Subtraction radiography requires radiographs made with identical projection geometry. Recently a new radiographic aiming device and an x-ray beam manipulator made it possible to repeat radiographic exposures in vivo with small angular errors and to measure the angular errors occurring. The purpose of the present inves...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.4.278
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:Periodontal disease results from the pathogenic interactions between the tissue, immune system, and microbiota; however, standard therapy fails to address the cellular mechanism underlying the chronic inflammation. Dendritic cells (DC) are key regulators of T cell fate, and biomaterials that recruit and prog...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0411
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:The aim of this study is to investigate effects of strontium ranelate (SR) on alveolar bone loss (ABL) in rats with experimental periodontitis. METHODS:Forty Wistar rats were randomly divided into five groups: 1) control (n = 8); 2) ligated (n = 8); 3) 300 mg/kg SR (SR300, n = 8); 4) 625 mg/kg SR (SR625, n ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160227
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:An immunohistochemical study was conducted to compare distributions of mast cell subpopulations in normal human gingiva and in gingival overgrowth induced by nifedipine and immunosuppressive medication. METHODS:Gingival samples were collected from 12 triple-medicated organ transplant recipients (immunosuppr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.7.933
更新日期:2004-07-01 00:00:00
abstract::Periodontal regeneration requires formation of periodontal tissues lost due to periodontal disease. To better understand the formation of new periodontal tissues during periodontal repair and regeneration, immunohistochemical expression of extracellular matrix components of normal as well as healing periodontal tissue...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.7.579
更新日期:1995-07-01 00:00:00
abstract::A new technique for the removal of phenytoin hyperplasia using the carbon dioxide (CO2) surgical laser is presented as well as a review of laser physics and the current uses of the CO2 laser in dentistry. Twelve cases of phenytoin hyperplasia removed surgically by the CO2 laser are presented; hence a laser gingivectom...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.8.492
更新日期:1985-08-01 00:00:00
abstract::This investigation studied the changes in probing depths and subgingival microbial flora of clinically healthy and diseased sites before and after scaling and root planing. Thirty-six sites in 18 individuals were studied in two groups of patients, Group I (9 patients) had received no periodontal surgery, while group I...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.7.391
更新日期:1984-07-01 00:00:00
abstract::Osseous grafting techniques represent one mode of therapy to manage combination pocket-osseous defects. They have their greatest applicability in the intrabony defect although encouraging results have been noted in furcation and suprabony sites. Like all treatment modalities, their usage is dictated by the therapeutic...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1977.48.9.570
更新日期:1977-09-01 00:00:00
abstract::A study of a consanguineous family with a high prevalence of localized juvenile periodontitis (LJP) and generalized prepubertal periodontitis (GPP) was done over a 7-and-a-half year period. The parents had adult periodontitis, while 2 daughters, aged 13 and 15, had LJP. Furthermore, 2 other daughters, ages 14 and 10, ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.5.457
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:The purpose of this single-masked, randomized, controlled clinical trial was to evaluate the effects of boric acid irrigation as an adjunct to scaling and root planing (SRP) on clinical and microbiologic parameters and compare this method with chlorhexidine irrigation and SRP alone in patients with chronic p...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2012.120467
更新日期:2013-09-01 00:00:00
abstract::The prevalence and features of 3 types of exostoses commonly encountered during periodontal surgery were studied in a sample of 328 modern American skulls drawn from the collection at the American Museum of Natural History. Measurements were made of the height, width, and breadth of exostoses. The relationship to teet...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.3.329
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:The long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. Periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. This study examined the im...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.2.131
更新日期:1999-02-01 00:00:00
abstract::The amounts of volatile sulfur compounds (VSC) and methyl mercaptan/hydrogen sulfide ratio in mouth air from patients with periodontal involvement were 8 times greater than those of control subjects. Our studies demonstrated that, in patients with periodontal disease: 1) the concentration of disulfide, which is conver...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1992.63.9.783
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Autoinducer (AI)-2 has an important role in biofilm formation in the oral environment. Mature biofilms formed as a result of the cell-to-cell communication make it difficult to overcome periodontitis with the use of antibiotics. Previous in vitro studies suggest that quorum-sensing inhibitors (QSIs) interfer...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160070
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Autologous bone grafts are usually well consolidated after 4 to 5 months but can be incompletely interlocked with the native bone. This study investigated the effect of acid demineralization of the graft-bed interface on graft consolidation. METHODS:Onlay bone grafts were performed on the calvaria of 36 gui...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130298
更新日期:2014-05-01 00:00:00