Effects of sodium meclofenamate on postoperative pain following periodontal surgery.

Abstract:

:The analgesic activity of single doses of meclofenamate (100 mg) was compared to aspirin (500 mg) and to placebo on 99 outpatients with moderate to severe pain following periodontal surgery under double-blind conditions. Pain intensity differences scores (PID) at the first, second, and third hour after the ingestion of the first capsule of each medication were used to determine the analgesic efficacy of the studied drugs. Kruskal Wallis test followed by the Mann-Whitney rank sum test were used in the statistical analysis of results. Meclofenamate was statistically superior to placebo and superior to aspirin in the second hour of evaluation, while aspirin was not superior to placebo during the 3-hour period of pain evaluation. It is concluded that meclofenamate is a non-steroidal antiinflammatory drug with interesting analgesic properties which can be used as directed as an alternative to aspirin or acetaminophen for the control of postoperative pain following periodontal surgery.

journal_name

J Periodontol

authors

Gallardo F,Rossi E

doi

10.1902/jop.1992.63.3.166

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

166-8

issue

3

eissn

0022-3492

issn

1943-3670

journal_volume

63

pub_type

临床试验,杂志文章
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  • Absence of periodontitis in a population of insulin-dependent diabetes mellitus (IDDM) patients.

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  • Tongue-cleaning methods: a comparative clinical trial employing a toothbrush and a tongue scraper.

    abstract:BACKGROUND:It is estimated that approximately 85% of all halitosis cases have their origin within the mouth; of these, 50% are caused by tongue residues. Previous studies have established that hydrogen sulfide and mercaptans are the primary components of halitosis. Thus, tongue cleaning gains importance as a means of h...

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  • Serum, saliva, and gingival crevicular fluid osteocalcin: their relation to periodontal status and bone mineral density in postmenopausal women.

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    pub_type: 杂志文章

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  • The role of IgE in the release of histamine from human gingival mast cells.

    abstract::Twelve gingival samples removed from 6 human volunteers were sectioned in small pieces, parts of which served as uncultured pieces. The remaining pieces were organ cultured for 5 hours in control, compound 48/80, and antihuman IgE media. Uncultured tissues, cultured tissues, and cultured spent media were analyzed spec...

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  • A comparative study of root coverage obtained with guided tissue regeneration utilizing a bioabsorbable membrane versus the connective tissue with partial-thickness double pedicle graft.

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    pub_type: 杂志文章

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  • Early intervention of peri-implantitis and periodontitis using a mouse model.

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    pub_type: 杂志文章

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    doi:10.1902/jop.2008.070132

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  • Histologic evaluation of the effects of intrasulcular toothbrushing on human sulcular epithelium.

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    doi:10.1902/jop.1978.49.4.163

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  • Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis.

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    doi:10.1902/jop.2008.070309

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  • A multi-center study comparing dual acid-etched and machined-surfaced implants in various bone qualities.

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1902/jop.2001.72.10.1384

    authors: Khang W,Feldman S,Hawley CE,Gunsolley J

    更新日期:2001-10-01 00:00:00

  • Preemptive dexamethasone and etoricoxib for pain and discomfort prevention after periodontal surgery: a double-masked, crossover, controlled clinical trial.

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  • Parameter on chronic periodontitis with slight to moderate loss of periodontal support. American Academy of Periodontology.

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    pub_type: 指南,杂志文章,实务指引

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  • Effects of guided bone regeneration around commercially pure titanium and hydroxyapatite-coated dental implants. II. Histologic analysis.

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    pub_type: 杂志文章

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  • The Influence of Glycated Hemoglobin on the Cross Susceptibility Between Type 1 Diabetes Mellitus and Periodontal Disease.

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    pub_type: 杂志文章

    doi:10.1902/jop.2015.150149

    authors: Lappin DF,Robertson D,Hodge P,Treagus D,Awang RA,Ramage G,Nile CJ

    更新日期:2015-11-01 00:00:00

  • A comparison of the reactivity of Eubacterium species with localized and serum immunoglobulins from rapidly progressive and adult periodontitis patients.

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    更新日期:1988-01-01 00:00:00

  • Periodontal disease in Kuna albinism: a comparative study.

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    pub_type: 杂志文章

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    更新日期:2007-01-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2002-04-01 00:00:00

  • Underestimation of periodontitis in NHANES surveys.

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    更新日期:2011-03-01 00:00:00

  • Surgical versus non-surgical periodontal treatment: psychosocial factors and treatment outcomes.

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    更新日期:2006-07-01 00:00:00

  • The effects of incubation length and temperature on the specificity and sensitivity of the BANA (N-benzoyl-DL-arginine-naphthylamide) test.

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    更新日期:1993-09-01 00:00:00

  • Redefining the biologic width in severe, generalized, chronic periodontitis: implications for therapy.

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