The multiple roles of estrogens and the enzyme aromatase.

Abstract:

:Aromatase is the enzyme that catalyzes the last step of estrogen biosynthesis. It is expressed in many tissues such as the gonads, brain and adipose tissue. The regulation of the level and activity of aromatase determines the levels of estrogens that have endocrine, paracrine and autocrine effects on tissues. Estrogens play many roles in the body, regulating reproduction, metabolism and behavior. In the brain, cell survival and the activity of neurons are affected by estrogens and hence aromatase.

journal_name

Prog Brain Res

authors

Boon WC,Chow JD,Simpson ER

doi

10.1016/S0079-6123(08)81012-6

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

209-32

eissn

0079-6123

issn

1875-7855

pii

S0079-6123(08)81012-6

journal_volume

181

pub_type

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