Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infection.

abstract：:Caprine arthritis encephalitis virus (CAEV) is a lentivirus closely related to visna virus and more distantly to other lentiviruses, such as human immunodeficiency virus. The genomes of visna virus and CAEV contain a tat gene encoding a protein able to weakly transactivate its own long terminal repeat, suggesting that...

journal_title：Journal of virology

authors： Harmache A,Vitu C,Russo P,Bouyac M,Hieblot C,Peveri P,Vigne R,Suzan M

更新日期：1995-09-01 00:00:00

abstract：UNLABELLED:The four serotypes of dengue virus (DENV) cause the most important and rapidly emerging arboviral diseases in humans. The recent phase 2b and 3 studies of a tetravalent dengue vaccine reported a moderate efficacy despite the presence of neutralizing antibodies, highlighting the need for a better understandin...

journal_title：Journal of virology

authors： Tsai WY,Durbin A,Tsai JJ,Hsieh SC,Whitehead S,Wang WK

更新日期：2015-07-01 00:00:00

abstract：:Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent involved in the disease HTLV-1-associated myelopathy, or tropical spastic paraparesis (HAM/TSP). The pathogenesis of HAM/TSP is poorly understood, but it is probable that viral infection has an indirect, deleterious effect on neural function. In ...

journal_title：Journal of virology

authors： Akaoka H,Hardin-Pouzet H,Bernard A,Verrier B,Belin MF,Giraudon P

更新日期：1996-12-01 00:00:00

abstract：:Using a DNA probe from an avian transforming virus, NK24, that contains the fos gene and that was newly isolated and characterized (M. Nishizawa, N. Goto, and S. Kawai, J. Virol. 61:3733-3740, 1987), we cloned and sequenced the chicken c-fos gene. Results showed that this gene, like the mouse or human c-fos gene, cont...

journal_title：Journal of virology

authors： Fujiwara KT,Ashida K,Nishina H,Iba H,Miyajima N,Nishizawa M,Kawai S

更新日期：1987-12-01 00:00:00

abstract：:Dengue virus (DENV) is an important human pathogen, especially in the tropical and subtropical parts of the world, causing considerable morbidity and mortality. DENV replication occurs in the cytoplasm; however, a high proportion of nonstructural protein 5 (NS5), containing methyltransferase (MTase) and RNA-dependent ...

journal_title：Journal of virology

authors： Kumar A,Bühler S,Selisko B,Davidson A,Mulder K,Canard B,Miller S,Bartenschlager R

更新日期：2013-04-01 00:00:00

abstract：:To determine the extent and structure of genetic variation in dengue viruses (DENV) on a restricted spatial and temporal scale, we sequenced the E (envelope) genes of DENV-1, -2, and -3 isolates collected in 2001 from children enrolled in a prospective school-based study in Kamphaeng Phet, Thailand, and diagnosed with...

journal_title：Journal of virology

authors： Jarman RG,Holmes EC,Rodpradit P,Klungthong C,Gibbons RV,Nisalak A,Rothman AL,Libraty DH,Ennis FA,Mammen MP Jr,Endy TP

更新日期：2008-06-01 00:00:00

abstract：:The RNA genome of human immunodeficiency virus type 1 (HIV-1) is converted into DNA after infection in order to integrate into the host cell DNA. However, a large number of these reverse-transcribed genomes remain unintegrated in the nucleus of infected cells. Currently, there are no data available about the intranucl...

journal_title：Journal of virology

authors： Bell P,Montaner LJ,Maul GG

更新日期：2001-08-01 00:00:00

abstract：:Autophagy and the effects of its inhibition or induction were investigated during the entire infectious cycle of varicella-zoster virus (VZV), a human herpesvirus. As a baseline, we first enumerated the number of autophagosomes per cell after VZV infection compared with the number after induction of autophagy followin...

journal_title：Journal of virology

authors： Buckingham EM,Carpenter JE,Jackson W,Grose C

更新日期：2014-01-01 00:00:00

abstract：:Viral infection induces production of type I interferons (IFNs), which stimulate the expression of a variety of antiviral factors to inhibit viral replication. To establish effective infection, viruses need to develop strategies to evade the immune responses. A neurovirulent Sindbis virus strain with neuroinvasive pro...

journal_title：Journal of virology

authors： Wang X,Li MMH,Zhao J,Li S,MacDonald MR,Rice CM,Gao X,Gao G

更新日期：2016-10-28 00:00:00

abstract：:We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses bear the C-terminal ligand sequence Glu-Ser-Glu-Val (ESEV) for PDZ domains present in multiple ...

journal_title：Journal of virology

authors： Zielecki F,Semmler I,Kalthoff D,Voss D,Mauel S,Gruber AD,Beer M,Wolff T

更新日期：2010-10-01 00:00:00

abstract：:Productive viral infection often depends on the manipulation of the cytoskeleton. Herpesviruses, including rhesus monkey rhadinovirus (RRV) and its close homolog, the oncogenic human gammaherpesvirus Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV8), exploit microtubule (MT)-based retrograde tran...

journal_title：Journal of virology

authors： Loftus MS,Verville N,Kedes DH

更新日期：2017-08-10 00:00:00

abstract：:Nucleocapsids were isolated from purified enveloped nucleocapsids of Plodia interpunctella granulosis virus by treatment with Nonidet P-40. When analyzed on sodium dodecyl sulfate-polyacrylamide gels, the nucleocapsids consisted of eight polypeptides. One of these, a major component with a molecular weight of 12,500 (...

journal_title：Journal of virology

authors： Tweeten KA,Bulla LA,Consigli RA

更新日期：1980-02-01 00:00:00

abstract：:The association of newly synthesized vesicular stomatitis virus proteins into nucleocapsid structures was examined in a cell-free system that supports concurrent viral protein synthesis, transcription, and RNA replication. The vesicular stomatitis virus proteins synthesized by this system associated with the newly rep...

journal_title：Journal of virology

authors： Patton JT,Davis NL,Wertz GW

更新日期：1983-01-01 00:00:00

abstract：:An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response. Remarkably, presentation of the naturally processed peptide of pp89, the nonapeptide YPHFMPTNL, is abolished during permis...

journal_title：Journal of virology

authors： Hengel H,Lucin P,Jonjić S,Ruppert T,Koszinowski UH

更新日期：1994-01-01 00:00:00

abstract：:Adenovirus gene therapy is a promising tool in the clinical treatment of many genetic and acquired diseases. However, it has also caused pathogenic effects in organs such as the liver. The redox-sensitive transcription factors AP-1 and NF-kappaB have been implicated in these effects. To study the mechanisms of adenovi...

journal_title：Journal of virology

authors： Zhang HJ,Drake VJ,Xu L,Hu J,Domann FE,Oberley LW,Kregel KC

更新日期：2002-01-01 00:00:00

abstract：:Nidoviruses (arteriviruses, coronaviruses, and roniviruses) are a phylogenetically compact but diverse group of positive-strand RNA viruses that includes important human and animal pathogens. Nidovirus RNA synthesis is mediated by a cytoplasmic membrane-associated replication/transcription complex that includes up to ...

journal_title：Journal of virology

authors： Nedialkova DD,Ulferts R,van den Born E,Lauber C,Gorbalenya AE,Ziebuhr J,Snijder EJ

更新日期：2009-06-01 00:00:00

abstract：:Recombinant poxvirus vectors are undergoing intensive evaluation as vaccine candidates for a variety of infectious pathogens. Avipoxviruses, such as canarypox virus, are replication deficient in mammalian cells by virtue of a poorly understood species-specific restriction. Highly attenuated vaccinia virus strains such...

journal_title：Journal of virology

authors： Zhang X,Cassis-Ghavami F,Eller M,Currier J,Slike BM,Chen X,Tartaglia J,Marovich M,Spearman P

更新日期：2007-07-01 00:00:00

abstract：:The viral early-to-late switch of papillomavirus infection is tightly linked to keratinocyte differentiation and is mediated in part by alternative mRNA splicing. Here, we report that SRp20, a cellular splicing factor, controls the early-to-late switch via interactions with A/C-rich RNA elements. An A/C-rich SE4 eleme...

journal_title：Journal of virology

authors： Jia R,Liu X,Tao M,Kruhlak M,Guo M,Meyers C,Baker CC,Zheng ZM

更新日期：2009-01-01 00:00:00

abstract：:After uptake into target cells, many nonenveloped viruses undergo conformational changes in the low-pH environment of the endocytic compartment. This results in exposure of amphipathic viral peptides and/or hydrophobic protein domains that are inserted into and either disrupt or perforate the vesicular membranes. The ...

journal_title：Journal of virology

authors： Bilek G,Matscheko NM,Pickl-Herk A,Weiss VU,Subirats X,Kenndler E,Blaas D

更新日期：2011-08-01 00:00:00

abstract：:Plasmacytoid dendritic cells (pDC) poorly replicate human immunodeficiency virus type 1 (HIV-1) but efficiently transfer HIV-1 to adjacent CD4 T lymphocytes. We found that coculture with T lymphocytes downregulates SAMHD1 expression, enhances HIV-1 replication, and increases pDC maturation and alpha interferon (IFN-α)...

journal_title：Journal of virology

authors： Su B,Lederle A,Laumond G,Ducloy C,Schmidt S,Decoville T,Moog C

更新日期：2014-09-01 00:00:00

abstract：:The recently developed subgenomic hepatitis C virus (HCV) replicons were limited by the fact that the sequence encoding the structural proteins was missing. Therefore, important information about a possible influence of these proteins on replication and pathogenesis and about the mechanism of virus formation could not...

journal_title：Journal of virology

authors： Pietschmann T,Lohmann V,Kaul A,Krieger N,Rinck G,Rutter G,Strand D,Bartenschlager R

更新日期：2002-04-01 00:00:00

abstract：:Primary infection of a plant with a pathogen that causes high accumulation of salicylic acid in the plant typically via a hypersensitive response confers enhanced resistance against secondary infection with a broad spectrum of pathogens, including viruses. This phenomenon is called systemic acquired resistance (SAR), ...

journal_title：Journal of virology

authors： Jeon EJ,Tadamura K,Murakami T,Inaba JI,Kim BM,Sato M,Atsumi G,Kuchitsu K,Masuta C,Nakahara KS

更新日期：2017-09-12 00:00:00

abstract：:We have investigated the species-specific replication of polyomavirus DNA in the cell-free system that was established previously (Y. Murakami, T. Eki, M. Yamada, C. Prives, and J. Hurwitz, Proc. Natl. Acad. Sci. USA 83:6347-6351, 1986). Extracts from various species of cells supported polyomavirus DNA replication in ...

journal_title：Journal of virology

authors： Eki T,Enomoto T,Masutani C,Miyajima A,Takada R,Murakami Y,Ohno T,Hanaoka F,Ui M

更新日期：1991-09-01 00:00:00

abstract：:The involvement of two bacteriophage T4 gene products in the initiation of T4 tail tube and sheath polymerization on mature baseplates has been studied by radioautography of acrylamide gels of various partially completed tail structures. The products of genes 48 and 54 (P48[the nomenclature P48 refers to the protein p...

journal_title：Journal of virology

authors： Berget PB,Warner HR

更新日期：1975-12-01 00:00:00

abstract：:We are using site-directed mutagenesis of single viral genes to identify and analyze the genetic determinants of human and simian immunodeficiency virus pathogenicity. In a first approach, we have constructed a series of simian immunodeficiency virus SIVmac nef mutants by partial deletion and insertions in the nef gen...

journal_title：Journal of virology

authors： Binninger D,Ennen J,Bonn D,Norley SG,Kurth R

更新日期：1991-10-01 00:00:00

abstract：:The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides. These si...

journal_title：Journal of virology

authors： St-Jean JR,Jacomy H,Desforges M,Vabret A,Freymuth F,Talbot PJ

更新日期：2004-08-01 00:00:00

abstract：:The human cytomegalovirus (HCMV) UL138 protein downregulates the cell surface expression of the multidrug resistance-associated protein 1 (MRP1) transporter. We examined the genetic requirements within UL138 for MRP1 downregulation. We determined that the acidic cluster dileucine motif is essential for UL138-mediated ...

journal_title：Journal of virology

authors： Gelbmann CB,Kalejta RF

更新日期：2019-05-15 00:00:00

abstract：:The locations of replication pause sites in the simian virus 40 minichromosome which were determined by sizing cloned fragments of nascent DNA (Zannis-Hadjopoulos et al., J. Mol. Biol. 165:599-607, 1983) were compared with the positions of simian virus 40 nucleosomes in the genome, as obtained by sequence-directed map...

journal_title：Journal of virology

authors： Trifonov EN,Mengeritsky G

更新日期：1984-12-01 00:00:00

abstract：:Analyses, by construction of phage growth curves, indicated that the polysaccharide depolymerase was synthesized by Pseudomonas aeruginosa strains B and BI after infection with phage 2. The kinetics of biosynthesis of the depolymerase were found to parallel closely the rate of formation of phage-directed virions, and ...

journal_title：Journal of virology

authors： Bartell PF,Orr TE

更新日期：1969-03-01 00:00:00

abstract：:All hepadnaviruses known so far have a very limited host range, restricted to their natural hosts and a few closely related species. This is thought to be due mainly to sequence divergence in the large envelope protein and species-specific differences in host components essential for virus propagation. Here we report ...

journal_title：Journal of virology

authors： Prassolov A,Hohenberg H,Kalinina T,Schneider C,Cova L,Krone O,Frölich K,Will H,Sirma H

更新日期：2003-02-01 00:00:00