Effects of a new thromboxane A2-antagonist (ONO-3708) and a new leukotriene-antagonist (ONO-1078) on thromboxane A2 analogue-, leukotriene C4-, and D4-induced regional myocardial blood flow reduction.

abstract：:The subendocardial side of myocardium makes a major contribution to left ventricular (LV) contraction and is very susceptible to ischemia. In this study we sought to quantify regional wall motion during low-dose dobutamine stress echocardiography (DSE) by using the myocardial velocity gradient (MVG) derived from tissu...

journal_title：Heart and vessels

authors： Tsutsui H,Uematsu M,Yamagishi M,Haruta S,Shimakura T,Miyatake K

更新日期：2000-01-01 00:00:00

abstract：:Myocardial fibrosis and microvascular dysfunction are key determinants of outcome in heart failure (HF); we examined their relationship in patients with HF. Our study included 61 consecutive patients with HF but without coronary stenosis. All underwent gadolinium-enhanced cardiac magnetic resonance to evaluate late ga...

journal_title：Heart and vessels

authors： Uemura T,Yamamuro M,Kaikita K,Takashio S,Utsunomiya D,Hirakawa K,Nakayama M,Sakamoto K,Yamamoto E,Tsujita K,Kojima S,Hokimoto S,Yamashita Y,Ogawa H

更新日期：2016-12-01 00:00:00

abstract：:Inflammatory markers are elevated in acute coronary syndromes, and are also known to play a crucial role in the pathogenesis of neointimal proliferation and stent restenosis. Drug-eluting stents (DESs) have been shown to decrease stent restenosis in different studies. In this study, we aimed to investigate the effect ...

journal_title：Heart and vessels

authors： Ozer N,Tangurek B,Firat F,Ozer S,Tartan Z,Ozturk R,Ozay B,Ciloglu F,Yilmaz H,Cam N

更新日期：2008-03-01 00:00:00

abstract：:It is well known that patients with gastroesophageal reflux disease (GERD) experience GERD-related chest pain, but little is known about the relationship between GERD and coronary artery disease (CAD). We evaluated medical history of GERD in patients with suspected CAD and its association with types of CAD. We enrolle...

journal_title：Heart and vessels

authors： Teragawa H,Oshita C,Ueda T

更新日期：2019-10-01 00:00:00

abstract：:Recently, the importance of central blood pressure for cardiovascular risk stratification has been emphasized. Accordingly, the differences in peak systolic and bottom diastolic pressures between the ascending aorta and the brachial artery should be clarified. Study subjects consisted of 82 consecutive patients with s...

journal_title：Heart and vessels

authors： Ohte N,Saeki T,Miyabe H,Sakata S,Mukai S,Hayano J,Niki K,Sugawara M,Kimura G

更新日期：2007-11-01 00:00:00

abstract：:An unusual case of total occlusion of aorta just distal to the left subclavian artery, bicuspid aortic valve, and occluded left external iliac artery in a 21-year-old man who was admitted with headache and severe hypertension is presented. We wish to report this case because so far there have been none reported with s...

journal_title：Heart and vessels

authors： Tanindi A,Tavil Y,Mutluay R,Taktak H,Cengel A

更新日期：2007-03-01 00:00:00

abstract：:Cerebral artery stenosis (CAS) has the same pathogenesis as coronary artery disease (CAD), but the coexistence of these two diseases has been rarely reported. To detect coexistent CAS in CAD patients, we conducted a study of simultaneous coronary and cerebral angiography. Of the 663 consecutive newly diagnosed CAD pat...

journal_title：Heart and vessels

authors： Li AH,Chu YT,Yang LH,Chen KC,Chu SH

更新日期：2007-09-01 00:00:00

abstract：:To define mechanisms that may influence collateral circulation and angiogenesis, we investigated vascular endothelial growth factor (VEGF) mRNA expression in human hearts. In non-ischemic human hearts, VEGF mRNA was not detected in vessels, but was found in cardiomyocytes. In hearts with myocardial infarction, the int...

journal_title：Heart and vessels

authors： Shinohara K,Shinohara T,Mochizuki N,Mochizuki Y,Sawa H,Kohya T,Fujita M,Fujioka Y,Kitabatake A,Nagashima K

更新日期：1996-01-01 00:00:00

abstract：:We assessed the plaque disruption in 245 consecutive patients with acute coronary syndrome undergoing percutaneous coronary intervention. The plaque fissure was diagnosed with optical coherence tomography, and intravascular ultrasound was used to determine arterial remodeling. Of them, 26 fissures were found in this s...

journal_title：Heart and vessels

authors： Goyal M,Kim SW,Mishra S,Sharmin S,Won H,Cho I,Jung MK,Shin SY,Lee KJ,Kim TH,Kim CJ,Lee WS

更新日期：2019-03-01 00:00:00

abstract：:This study is a prospective evaluation of the effectiveness of cardiac rehabilitation (CR) in terms of clinical outcomes for small abdominal aortic aneurysms (AAA) that were previously reported in a retrospective cohort study. We conducted a prospective non-randomized trial on patients with small AAA (N = 40; mean age...

journal_title：Heart and vessels

authors： Nakayama A,Amiya E,Morita H,Hyodo K,Takayama N,Konishi Y,Taya M,Fujiwara T,Hosoya Y,Hoshina K,Komuro I

更新日期：2019-12-01 00:00:00

abstract：:Intracoronary acetylcholine (ACh) provocation test is useful to diagnose vasospastic angina. Although outpatient coronary angiography has been widely performed in current clinical settings, the feasibility and safety of ACh provocation test in outpatient services are unclear. A total of 323 patients, who electively un...

journal_title：Heart and vessels

authors： Saito Y,Kitahara H,Shoji T,Tokimasa S,Nakayama T,Sugimoto K,Fujimoto Y,Kobayashi Y

更新日期：2018-08-01 00:00:00

abstract：:The progression of cardiac hypertrophy and failure is associated with marked changes in cardiac autonomic innervation, and there are sympathetic-parasympathetic interactions in the regulation of cardiac function. Although the indexes of sympathetic innervation have been found to be depressed with the development of he...

journal_title：Heart and vessels

authors： Yamada Y,Okumura K,Hashimoto H,Ito T,Satake T

更新日期：1991-01-01 00:00:00

abstract：:Although apical and midventricular Takotsubo cardiomyopathies (TTCs) share common triggers and pathophysiological features, little is known about the potential differences in left ventricular (LV) mechanistic properties between these TTC phenotypes. We sought to investigate whether LV systolic and/or diastolic functio...

journal_title：Heart and vessels

authors： Messas N,Trimaille A,Marchandot B,Matsushita K,Kibler M,Hess S,Marquis-Gravel G,Jolicoeur EM,Jesel L,Ohlmann P,Morel O

更新日期：2020-04-01 00:00:00

abstract：:We investigated the incidence of post-intubation hypotension (PIH) in hemodynamically stable patients with STEMI requiring rapid sequences intubation (RSI) and medicated with ketamine or midazolam as induction agent. STEMI patients admitted between 1st January 2009 and 1st January 2017 who did not receive any type of ...

journal_title：Heart and vessels

authors： Zuin M,Rigatelli G,Dell'Avvocata F,Faggian G,Conte L,Giatti S,Michielan F,Roncon L

更新日期：2018-03-01 00:00:00

abstract：:No studies have evaluated both the time-to-isolation (TTI) and the sequence of pulmonary vein (PV) potentials in cryoballoon ablation (CBA) for atrial fibrillation (AF). This study aimed to prospectively evaluate the acute results of pulmonary vein isolation (PVI) using a novel CBA technique-the earliest potential (EP...

journal_title：Heart and vessels

authors： Mizutani Y,Kanashiro M,Makino Y,Satake A,Suzuki W,Kurobe M,Mizutani K,Ichimiya H,Uchida Y,Watanabe J,Ichimiya S,Inden Y,Murohara T

更新日期：2020-02-01 00:00:00

abstract：:Previous studies suggested that sleep-disordered breathing was associated with cardiovascular diseases such as heart failure (HF). Recently, algorithms of cardiac implantable electronic devices (CIEDs) have been developed to detect advanced sleep apnea (SA); the Apnea Scan (AP Scan) being an example. The purpose of th...

journal_title：Heart and vessels

authors： Wakabayashi Y,Koyama T,Kurihara K,Kobayashi M,Ichikawa T,Abe H

更新日期：2020-06-01 00:00:00

abstract：:This study evaluates the clinical significance of re-elevation of T-wave in patients with ST segment elevation acute myocardial infarction (STEMI) undergoing successful percutaneous coronary intervention (PCI). Resolution of ST elevation within 24 h after reperfusion is associated with better outcome. However, little ...

journal_title：Heart and vessels

authors： Nishizaki F,Tomita H,Yokoyama H,Higuma T,Abe N,Suzuki A,Endo T,Tateyama S,Ishida Y,Osanai T,Okumura K

更新日期：2013-11-01 00:00:00

abstract：:Acromegaly, when left untreated, is associated with premature mortality which is chiefly related to cardiovascular complications. We report on a 50-year-old acromegalic woman, resistant to therapy, who died suddenly because of thoracic aortic rupture and massive bleeding into the left pleural space. The postmortem exa...

journal_title：Heart and vessels

authors： Maffei P,Menegazzo C,Michelotto M,Salmaso R,Martini C,De Carlo E,Carli M,Barban M,Fassina A,Vettor R,Sicolo N

更新日期：2008-01-01 00:00:00

abstract：:The efficacy of second-generation drug-eluting stent (DES) for the treatment of left main disease (LM) and/or three vessel disease (3VD) remains unclear. We compared 2-year outcomes of second- versus first -generation DES implantation among patients with LM and/or 3VD and to assess the differential of risk by complexi...

journal_title：Heart and vessels

authors： Kobayashi N,Ito Y,Hirano K,Yamawaki M,Araki M,Sakai T,Takimura H,Sakamoto Y,Mori S,Tsutsumi M,Takama T,Takafuji H,Maruyama T,Honda Y,Tokuda T,Makino K,Shirai S,Muramatsu T

更新日期：2016-12-01 00:00:00

abstract：:We analyzed whether smoking was associated with major adverse cardiovascular events (MACE) and the progression of coronary atherosclerosis as assessed by coronary computed tomography angiography (CCTA) as screening for coronary artery disease (CAD). We enrolled 443 patients who had all undergone CCTA and either were c...

journal_title：Heart and vessels

authors： Higashi S,Shiga Y,Yano M,Imaizumi T,Tashiro K,Idemoto Y,Kato Y,Kuwano T,Sugihara M,Miura SI

更新日期：2020-11-27 00:00:00

abstract：:During left nephrectomy in a 35-year-old woman with a left renal cell carcinoma extending into the inferior vena cava (IVC) and right atrium, cardiac arrest occurred. Immediate transesophageal echocardiography demonstrated that the event was caused by a pulmonary tumor embolism. Emergent cardiopulmonary bypass (CPB) w...

journal_title：Heart and vessels

authors： Nagasaka S,Taniguchi S,Kobayashi S,Kawata T,Mizuguchi K,Hirao Y,Kitamura S

更新日期：1997-01-01 00:00:00

abstract：:We report herein an adult case of anomalous origin of the left coronary artery from the pulmonary artery (Bland-White-Garland syndrome; BWG syndrome). The patient had chest discomfort during exercise and signs of mitral regurgitation. We diagnosed him as having BWG syndrome by angiography, and performed surgical treat...

journal_title：Heart and vessels

authors： Ishihata T,Takeda H,Katohno E,Techigawara M,Owada K,Murata N,Ohta H,Maruyama Y

更新日期：1994-01-01 00:00:00

abstract：:The aim of this study was to evaluate the relation between aortic artery distensibility, expressed by pulse pressure (PP) and autonomic nervous system function expressed by heart rate variability (HRV), among elders. During 2009, 469 individuals (50 % males, mean age 75 ± 6 years old), permanent inhabitants of Ikaria ...

journal_title：Heart and vessels

authors： Chrysohoou C,Skoumas J,Oikonomou E,Tsiachris D,Metaxa V,Lagoudakou S,Felekos J,Masoura C,Athanassopoulou S,Kosyfa H,Pitsavos C,Stefanadis C

更新日期：2013-07-01 00:00:00

abstract：:Lamotrigine has been used for patients with epilepsy and/or bipolar disorder, overdose of which induced the hypotension, elevation of the atrial pacing threshold, cardiac conduction delay, wide complex tachycardia, cardiac arrest and Brugada-like electrocardiographic pattern. To clarify how lamotrigine induces those c...

journal_title：Heart and vessels

authors： Goto A,Hagiwara-Nagasawa M,Kambayashi R,Nunoi Y,Izumi-Nakaseko H,Kawai S,Takei Y,Matsumoto A,Sugiyama A

更新日期：2020-11-02 00:00:00

abstract：:Elastase (ELA) is an enzyme catalyzing the digestion of elastin, an essential constituent of elastic fibers. Using isolated guinea pig papillary muscles, we examined the effect of ELA (3 x 10(-7) -3 x 10(-4) g/ml) on resting tension (RT) and twitch tension (TT). The effects of ELA on elastic fibers located in the sube...

journal_title：Heart and vessels

authors： Sato T,Imanishi S,Arita M,Shimada T

更新日期：1993-01-01 00:00:00

abstract：:Gradient-echo T2-star (T2*)-weighted magnetic resonance imaging (MRI) is a sensitive method to detect cerebral microbleeds (CMBs). The presence of CMBs was reported to be a marker of future cardiovascular mortality and is associated with various cardiovascular risk factors, use of antithrombotic drugs, and cognitive d...

journal_title：Heart and vessels

authors： Watanabe T,Kanzaki Y,Yamauchi Y,Ito T,Nishida Y,Yamamura K,Komori T,Sohmiya K,Hoshiga M

更新日期：2020-03-01 00:00:00

abstract：:Although the ultimate cause for the myocardial dysfunction of hypertensive heart disease is still unclear, a crucial role of the myocardial energy metabolism has been suggested. Therefore, the aim of the present study was to investigate whether age-related myocardial dysfunction in hearts of spontaneously hypertensive...

journal_title：Heart and vessels

authors： Perings SM,Schulze K,Decking U,Kelm M,Strauer BE

更新日期：2000-01-01 00:00:00

abstract：:Heme oxygenase (HO)-1 is a rate-limiting enzyme for degrading heme into carbon monoxide. Longer (GT)n repeat of the HO-1 gene (HMOX1) promoter has a lower transcription rate. Subjects with longer GT repeats in the HMOX1 promoter are more likely to have coronary artery disease (CAD) and cardiovascular events. We retros...

journal_title：Heart and vessels

authors： Liang KW,Lee WJ,Lee WL,Wu JP,Lee IT,Wang JS,Sheu WH

更新日期：2021-01-03 00:00:00

abstract：:The role of inflammation in acute coronary syndrome (ACS) and the mechanism by which statin treats ACS is explored. Serum high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels were measured in 50 patients with ACS [including 30 cases with unstable angina (UA) and 20 patients with acute myocardia...

journal_title：Heart and vessels

authors： Luo Y,Jiang D,Wen D,Yang J,Li L

更新日期：2004-11-01 00:00:00

abstract：:The aim of our study was to assess the atherosclerotic burden in patients with the first symptoms of coronary artery disease (CAD). The study population consisted of 100 consecutive patients (new-onset severe angina or myocardial infarction) and 70 age- and sex-matched volunteers without symptoms of CAD. Functional an...

journal_title：Heart and vessels

authors： Cerne A,Kranjec I

更新日期：2002-09-01 00:00:00