Abstract:
:Acromegaly, when left untreated, is associated with premature mortality which is chiefly related to cardiovascular complications. We report on a 50-year-old acromegalic woman, resistant to therapy, who died suddenly because of thoracic aortic rupture and massive bleeding into the left pleural space. The postmortem examination disclosed, nearby the point of rupture, a pulmonary abscess as well as extensive intrinsic alteration of arteries originating from the aortic arch and aorta itself, which featured microscopic cystic medial necrosis. We discussed how these aspects could be related to long-term exposition to growth hormone excess. In particular, this case gives further evidence of vascular system frailty in acromegaly.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Maffei P,Menegazzo C,Michelotto M,Salmaso R,Martini C,De Carlo E,Carli M,Barban M,Fassina A,Vettor R,Sicolo Ndoi
10.1007/s00380-007-1012-ysubject
Has Abstractpub_date
2008-01-01 00:00:00pages
71-4issue
1eissn
0910-8327issn
1615-2573journal_volume
23pub_type
杂志文章abstract::A growing body of evidence suggests that mitral regurgitation (MR) is associated with higher mortality in heart failure patients with reduced ejection fraction. However, prognostic impact of MR on heart failure patients with preserved ejection fraction (HFpEF) has not been fully examined. The Japanese Heart Failure Sy...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-020-01581-5
更新日期:2020-08-01 00:00:00
abstract::A 65-year-old man was referred to our hospital following repetitive chest pain. Invasive coronary angiography showed an intermediate stenosis of the proximal left anterior descending artery (LAD), and a coronary fistula originating distal to the stenosis draining into the main pulmonary artery. To evaluate the functio...
journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
abstract::Even though drug-coated balloon (DCB) angioplasty has emerged as a treatment option for drug-eluting stent in-stent restenosis (DES-ISR), the most effective treatment strategy for DES-ISR is still under debate. Therefore, we compared long-term clinical outcomes following DCB treatment of DES-ISR with those following 2...
journal_title:Heart and vessels
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abstract::The purpose of this study was to examine factors influencing readmission to hospital in patients with heart failure. This multicenter, retrospective cohort study analyzed 197 heart failure patients admitted to the research cooperation facilities between January 2017 and November 2017. We defined the readmission group ...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
doi:10.1007/s00380-019-01500-3
更新日期:2020-03-01 00:00:00
abstract::Predictors of outcomes in patients with heart failure with preserved left-ventricular ejection fraction (HFpEF) remain unclear. The ratio of early diastolic transmitral flow velocity to early diastolic myocardial velocity (E/e') has been proposed, but the predictive accuracy remains unsatisfactory. We hypothesized tha...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1211-8
更新日期:2018-12-01 00:00:00
abstract::Although the number of pregnancies in women with cardiac disease is increasing worldwide, there are few data concerning their clinical characteristics and peripartum outcomes. Using the Diagnosis Procedure Combination database between 2008 and 2014 in Japan, we retrospectively identified pregnant women who underwent h...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
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更新日期:2018-08-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-010-0029-9
更新日期:2011-01-01 00:00:00
abstract::Very late stent thrombosis (VLST) is a serious complication after percutaneous coronary intervention. However, the best therapy for VLST with late-acquired incomplete stent apposition and incomplete neointimal coverage remains unknown. In these cases, neointimal coverage was nearly complete and no late-acquired malapp...
journal_title:Heart and vessels
pub_type: 杂志文章
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2006-03-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058280
更新日期:1991-01-01 00:00:00
abstract::Regardless of a successful operation, patients with coarctation of aorta (CoAo) are exposed to the risk of hypertension and a propensity to vascular and end-organ damage. The aim of this study is to evaluate the influence of residual aorta stenosis as well as the age at the operation on the parameters of arterial func...
journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2011-07-01 00:00:00
abstract::Chronic kidney disease (CKD) is well known to be associated with an increased incidence of coronary artery disease (CAD). Diabetes mellitus (DM) and hypertension (HTN), both of which are traditional risk factors for CAD, are the two most common causes of CKD. However, the influence of CKD on coronary atherosclerosis i...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-01334-5
更新日期:2019-07-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01746067
更新日期:1994-01-01 00:00:00
abstract::We report the case of a newborn with an aneurysmal aorto-left ventricular tunnel causing significant paravalvular aortic regurgitation and obstruction of the right ventricular outflow tract (RVOT), coexisting with a bicuspid aortic valve. The coexistence of the two malformations together with the obstruction of the RV...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-013-0445-8
更新日期:2015-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0745-2
更新日期:2016-09-01 00:00:00
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journal_title:Heart and vessels
pub_type: 临床试验,杂志文章
doi:10.1007/BF02767127
更新日期:1997-01-01 00:00:00
abstract::T cells are involved in the pathogenesis of atherosclerosis. We aimed to search for any association between the peripheral T-cell activities and atherogenic risk factors in healthy subjects. Fifty male volunteers (age 22.0 +/- 2.4 years) were enrolled. No subject had any chronic disease or was under any drug treatment...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-005-0893-x
更新日期:2006-07-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-0952-0
更新日期:2017-08-01 00:00:00
abstract::Ischemic cardiomyopathy complicated by severe mitral regurgitation (MR) has a poor prognosis. In such cases, whether mitral valve repair for MR improves the prognosis of survival remains unclear. In this study, 50 patients diagnosed with ischemic cardiomyopathy at our hospital between August 1991 and August 1996 were ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-004-0763-y
更新日期:2004-07-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1985-05-01 00:00:00
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journal_title:Heart and vessels
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更新日期:2018-11-01 00:00:00
abstract::Electrocardiographic left ventricular hypertrophy (ECG-LVH) gradually regressed after aortic valve replacement (AVR) in patients with severe aortic stenosis. Sokolow-Lyon voltage (SV1 + RV5/6) is possibly the most widely used criterion for ECG-LVH. The aim of this study was to determine whether decrease in Sokolow-Lyo...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0761-2
更新日期:2016-09-01 00:00:00
abstract::Cerebral artery stenosis (CAS) has the same pathogenesis as coronary artery disease (CAD), but the coexistence of these two diseases has been rarely reported. To detect coexistent CAS in CAD patients, we conducted a study of simultaneous coronary and cerebral angiography. Of the 663 consecutive newly diagnosed CAD pat...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-006-0971-8
更新日期:2007-09-01 00:00:00
abstract::Morphological and functional changes of free arterial grafts in dogs were studied for 3 weeks after implantation and the changes were compared to those in implanted free vein grafts. In the arterial grafts, endothelial cells with abundant pinocytotic vesicles and some cytoplasmic folds were observed by transmission an...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01744868
更新日期:1992-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-008-1071-8
更新日期:2009-01-01 00:00:00
abstract::Activation of mineralocorticoid receptor antagonists (MRAs) is cardioprotective; however, this property is lost upon blockade or inactivation of adenosine (ADO) receptor A2b. In this study, we investigated whether the effects of MRAs are mediated by an interaction between cardioprotective ADO receptors A1 and A3. Spir...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01542-7
更新日期:2020-05-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0609-1
更新日期:2016-03-01 00:00:00
abstract::The clinical efficacy of glucagon-like peptide-1 (GLP-1) analogs in patients with acute myocardial infarction (AMI) is uncertain. The purpose of the present study was to evaluate the effects of the GLP-1 analog liraglutide on left ventricular (LV) remodeling in patients with AMI. We retrospectively evaluated the effec...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0734-5
更新日期:2016-08-01 00:00:00